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  • diffusion
  • The results show that the measuring range for protein sensing on nanopore electrodes is shifted to lower concentrations by more than 1 order of magnitude, which is explained with the reduction of surface area by the nanopore membrane and the related more effective hemispherical diffusion pattern. (edu.au)
  • sensors
  • The operation of ion channel sensors is mimicked with functionalized polymeric membrane electrodes, using a surface confined affinity reaction to impede the electrochemically imposed ion transfer kinetics of a marker ion. (edu.au)
  • We suggest a novel role for both NaKA and NHE3 that extends beyond ion translocation and conclude that they can act as directional sensors and V mem as a regulatory cue which maintain the persistent direction in electrotaxis. (biomedcentral.com)
  • hydrophilic
  • Because the sensitivity of protein sensing is dependent on the effective blocking of the active surface area, it can be improved with a hydrophilic nanopore membrane applied on top of the biotinylated ion-selective membrane surface. (edu.au)
  • structures
  • Knowledge of channel structures as well as dynamic changes in these structures is crucial to fully understand how an ion channel works under normal physiological conditions and how channel functions are affected under pathological conditions. (physiology.org)
  • aqueous
  • A macroporous amphoteric ion exchange membrane was prepared by blending chitosan (CS) and carboxymethylcellulose (CMC) in aqueous solution, with glutaraldehyde as a crosslinking agent and silica particles as porogens. (hindawi.com)
  • The results indicate that the protein accumulates on the ion-selective membrane surface, partially blocking the current-induced ion transfer across the membrane/aqueous sample interface, and subsequently decreases the potential jump in the so-called super-Nernstian step that is characteristic of a surface depletion of the marker ion. (edu.au)
  • targets
  • Other proteins are currently being produced and optimized in ours labs throught internal research efforts (see our Pipeline ) and we also have the capacity to work on any membrane protein targets through our fee-for-service model . (calixar.com)
  • Characterization
  • On the basis of cyclic voltammetry characterization, the nanoporous membrane electrodes can indeed be understood as a recessed nanoelectrode array. (edu.au)
  • sensitivities
  • In this work, differences between two varieties of rice with contrasting salt sensitivities were revealed by the imaging of photosynthetic parameters, ion content analysis and a transcriptomic approach. (frontiersin.org)
  • computational
  • Hi Maximilien, depending on what exactly the questions are that you like to address, the double-membrane setup as used in computational electrophysiology setups might be helpful for you. (kth.se)
  • Channel
  • Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein. (physiology.org)
  • In the past 5 years patch fluorometry ( 46 , 47 ) has emerged as a novel tool that sheds new light on ion channels by providing a direct link between the channel structure and its function. (physiology.org)
  • bilayer
  • 2016. Bilayer networks within a hydrogel shell: A robust chassis for artificial cells and a platform for membrane studies . (cardiff.ac.uk)
  • structure
  • A scanning electron microscope was used to observe the morphology of CS/CMC blend membranes, in which a three-dimensional opening structure was formed, and no phase separation was discovered. (hindawi.com)
  • This structure of the 434 Cro protein complexed with a 20 base pair piece of DNA containing its Operator OR1 was determined by A.Mondragon & S.C.Harrison (protein data bank accession code 3cro). (smu.edu)