Ionization methods in organic mass spectrometry. Medical search. Frequent questions

A flow-injection analysis tandem mass spectrometry (FIA MSMS) method was developed for rapid quantitative analysis of 10 different inorganic and organic explosives. (mit.edu)
The purposes of this study were to develop a sensitive, specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for detection of 25-hydroxyvitamin D(2) and D(3) and establish reference intervals for these analytes. (nih.gov)
Measurement of folic acid and 5-methyltetrahydrofolate (5-methylTHF) in a subset of stored serum samples from NHANES 2001-2002 to allow comparison of CDC liquid chromatography tandem mass spectrometry (LC-MS/MS) method to data generated previously by Tufts University HPLC method with electrochemical detection. (cdc.gov)
An isotope-dilution tandem mass spectrometry method coupled to liquid chromatography (LC-MS/MS) was used to measure folate forms in serum. (cdc.gov)
Surprisingly, bacteria in the stationary phase produced N-acyl-phosphatidylethanolamine (NAPE) and another rare lipid we tentatively name as 1-phosphatidyl-2-acyl-glycero-3-phosphoethanolamine (PAGPE) based on tandem mass spectrometry. (nature.com)
Using tandem mass spectrometry for metabolic disease screening among newborns: a report of a work group. (cdc.gov)
Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens. (cdc.gov)
METHODS: To characterize PFAS exposures in ACHS I and ACHS II, we measured eight environmentally significant PFAS in serum by UPLC coupled electrospray ionization tandem mass spectrometry. (cdc.gov)

A novel approach, which utilizes collision-induced dissociation of fragmentation pathway leading to a characteristic fragmentation pattern by coupling microflow liquid chromatography to atmospheric pressure chemical ionization of quadrupole time-of-flight mass spectrometry, was used to further clarify the trace amount of key components present in simulated road paving asphalt fumes. (cdc.gov)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used as a microbial identification technique for more than a decade , overcoming the limitations of classical biochemical methods that can take days for a result and often lack specificity. (technologynetworks.com)
Trapped ion mobility spectrometry (TIMS) combined with quadrupole time of flight mass spectrometry (Q-TOF). (lu.se)

Wang and colleagues (11) developed a nondestructive laser desorption ionization mass spectrometry method that successfully classified 38 red ink entries into seven groups. (spectroscopyonline.com)
Thus, Digital MicroFluidic (DMF) Lab-On-Chip devices have been coupled with off-line Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) analysis as an alternative to optical methods [3]. (science24.com)
In this presentation, I will discuss an original study consisting of coupling EWOD-DMF and matrix-free Laser Desorption/Ionization Mass Spectrometry (LDI-MS) analysis using superhydrophobic nanostructured silicon substrates. (science24.com)

The new extraction and detection method employs capillary electrophoresis with electrospray ionization mass spectrometry (CE-ESI MS) and was specifically developed to determine polar organic compounds in the ACI PM emissions. (sae.org)
We prior knowledge of nucleic acid sequence information is use broad-range PCR to generate amplification products required to develop these tests, they are not able to identi- from the broadest possible grouping of organisms, followed fy unanticipated, newly emergent, or previously unknown by electrospray ionization mass spectrometry and base infectious organisms. (cdc.gov)
Electrospray ionization mass spectrometry can test the molecular weight of the object. (pharmaceuticalsteroids.com)

Both liquid and gas chromatography coupled to mass spectrometry (LC-MS and GC-MS, respectively) have been used in targeted and untargeted experiments but require the use of isotopically labeled substrates to glean information on the dynamic processes of DCs. (chromatographyonline.com)

These polar compounds contribute to OC in the PM and are not typically measured using nonpolar solvent extraction methods such as the soluble organic fraction (SOF) method. (sae.org)
Detection of Polar Compounds Condensed on Particulate Matter Using Capillary Electrophoresis-Mass Spectrometry," SAE Technical Paper 2020-01-0395, 2020, https://doi.org/10.4271/2020-01-0395 . (sae.org)
As deviations between the molecular and the ionic composition can appear due to chemical influences on the ion fragmentation processes, the method was evaluated and calibrated using spectra from 20 compounds from the NIST database and from 35 laboratory standards sampled with the high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS). (nasa.gov)
We use gas chromatography (GC) to resolve complex mixtures of gases, and volatile and semi-volatile compounds, coupled with mass spectrometry (GC-MS) and other detectors such as flame ionisation (FID) and electron capture (ECD). (ncl.ac.uk)
Saturation vapor pressure ( p sat ) is an important thermodynamic property regulating the gas-to-particle partitioning of organic compounds in the atmosphere. (copernicus.org)
Low-volatility organic compounds (LVOCs), with sufficiently low p sat values, primarily stay in the particle phase and contribute to aerosol formation. (copernicus.org)
2009). Gas-phase oxidation of volatile organic compounds leads to a range of organic vapors with different functionalities and thus volatility. (copernicus.org)
2009). Particular attention has been paid to low-volatility organic compounds (LVOCs), which significantly contribute to SOA formation (Ehn et al. (copernicus.org)
NP-LC has been widely used to separate various compounds, from nonpolar to highly polar compounds (note that chromatography was first introduced as a method used in separation science). (springer.com)
A desirable mobile phase would contain high organic content for better sensitivity and also show good on-column retention for polar ionic compounds. (springer.com)
Organic compounds can stick to the walls of the sample introduction system causing drift and variability. (elgalabwater.com)
Nuclear magnetic resonance is the basic method for the identification of organic compounds. (pharmaceuticalsteroids.com)
the binders are polymers and the fillings and some pigments are inorganic compounds, which are difficult to analyze using the chromatographic methods. (spectroscopyonline.com)
It has been shown that the method can be used to obtain compounds with the aforementioned structural fragments separated by one or two methylene units. (edu.ua)
The book is aimed at undergraduates, graduate students and practitioners as they develop expertise in the structural elucidation of organic compounds. (chemistryworld.com)
SESI, a soft ionization method, is described by the researchers as being able to operate at ambient pressure and detect volatile organic compounds (VOCs) in the low parts per trillion range. (chromatographyonline.com)
The next focuses on using these three techniques together to determine the structures of organic compounds. (acadiasi.ro)
We develop and optimize analytical methods for organic and organometallic compounds, using either liquid chromatography (UHPLC) or supercritical fluid chromatography (SFC) with MS and MS/MS characterization or quantification. (lu.se)
Gas chromatography mass spectrometry is also available for the analysis of volatile compounds, as well as a state-of-the-art pipetting robot for automated sample preparation. (lu.se)
This sensitive and robust triple quadrupole mass spectrometer is used for analysis of low (ppb) levels of environmental compounds and biomarkers. (lu.se)
This instrument is used for the characterization of synthesized or isolated organic and organometallic compounds. (lu.se)
Routine work includes determination of molecular formula and accurate mass with an accuracy of ± 1 mDa of compounds with m/z up to 3000 mDa. (lu.se)

Following World War II the techniques of manipulating very short electrical pulses allowed the construction of the time-of-flight mass spectrometer , in which a short emission of ions is released from the source and their arrival times recorded after having traversed a distance sufficiently long to sort out the different speeds. (britannica.com)
In 1953 the West German physicists Wolfgang Paul and Helmut Steinwedel described the development of a quadrupole mass spectrometer . (britannica.com)
Throughout these projects, the mass spectrometer was transported to the sample rather than the sample to the instrument thus emphasizing the importance of a robust analytical instrument capable of qualitative and quantitative analysis. (purdue.edu)
To achieve these goals, the mass spectrometer was adapted to the problem by varying the ionization method, building new hardware, or even modifying the data analysis system. (purdue.edu)
The laboratory also has LC-MS systems and a thermogravimetric analyser interfaced to a mass spectrometer (TGA-MS). (ncl.ac.uk)
The Netzsch Jupiter STA 449C is a thermogravimetric analyser interfaced to an Aeolos QMS 403 quadrupole mass spectrometer. (ncl.ac.uk)
Alternatively, in ICP-MS, the ions can be extracted into a mass spectrometer and their charge ratio and abundance measured. (elgalabwater.com)
To paraphrase the poet Robert Browning, a mass spectrometer (MS)'s reach should exceed its grasp. (chromatographyonline.com)
Once separated by LC, the amino acids enter the mass spectrometer for detection and quantification. (pharmiweb.com)
The mass spectrometer ionizes the derivatized amino acids, generating charged ions that are subsequently analyzed based on their mass-to-charge ratio (m/z). (pharmiweb.com)
A small sample of the compound is vaporised in a mass spectrometer under high vacuum and then subjected to bombardment by a beam of high-energy electrons. (acadiasi.ro)
Rule 2, omit O, gives C7H14 The three essential functions of a mass spectrometer, and the associated components, are: Note: DOU = #Cs+1-0.5(#Hs-#Ns+#halogens). (acadiasi.ro)

Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in this website by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publications. (rush.edu)
Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles. (rush.edu)
Many objects and surfaces are simply too large (or have other complicating circumstances) to be positioned immediately adjacent to the MS, necessitating some form of transfer between the atmospheric pressure desorption/ionization site and the instrument inlet. (chromatographyonline.com)
At the cost of orders of magnitude in signal reduction, the tubing conducted desorption electrospray ionization (DESI) analytes from sample surfaces 3 m distant (2). (chromatographyonline.com)

Allows identification and quantification of amino acids by measuring their mass-to-charge ratio. (pharmiweb.com)

A specific liquid chromatography-mass spectrometry/mass spectrometry spectrometric procedure for the quantitation of amprenavir drug in biological matrices was developed and validated. (japsonline.com)
A mass spectrometric technique that is used for the analysis of large biomolecules. (rush.edu)
Consequently, a lot of effort is put into identifying the constituent proteins using mass spectrometric methods. (lu.se)
Mass [10] together with information on modifications induced by sample prepa- ration procedures for mass spectrometric analysis, but mass changes are only given as integer values. (lu.se)

The book fits very well the problem-solving workshop approach used to teach organic structure elucidation in undergraduate courses, certainly in UK universities. (chemistryworld.com)

The application of superimposed radio frequency and constant potentials between four parallel rods can be shown to act as a mass separator in which only ions within a particular mass range will perform oscillations of constant amplitude and be collected at the far end of the analyzer. (britannica.com)
New applications and new developments have gone hand in hand to create a complex array of instruments, but all may be understood by tracing the ions through three basic elements: an ion source, a method of analyzing the ion beams according to their mass-to-charge ratio, and detectors capable of measuring or recording the currents of the beams. (britannica.com)
the positive ions contribute in turn to further ionization by their collisions. (britannica.com)
One disadvantage of this kind of ionization is the wide band of energies attained by the ions, ranging from the maximum electrode potential to almost zero. (britannica.com)
A satisfactory electrode arrangement enables the production of a beam of ions much more nearly homogeneous in energy than with the arc, greatly simplifying the ensuing analyzing method. (britannica.com)
Mass spectrometry refers to the generation and analysis of ions according to their mass-to-charge. (purdue.edu)
The composition of the analyzed samples is approximated by the average elemental composition of the ions from high-resolution electron ionization (EI) mass spectra. (nasa.gov)
Solutions are atomised and ionised in a high energy plasma and the resulting ions measured by mass spectrometry. (elgalabwater.com)
They can also interfere by producing ions with masses close to the elements of interest and by affecting the ionisation efficiency of the plasma. (elgalabwater.com)
The ever-increasing sensitivity of commercial mass spectrometry (MS) instrumentation has enabled it to detect analyte ions generated at atmospheric pressure farther from the vacuum interface. (chromatographyonline.com)
Early successes in ambient ionization source design led the Cooks laboratory to test the limits of pulling ions through a stainless steel tube. (chromatographyonline.com)
The first non-proximate analysis method to examine organic molecules in complex samples, REIMS was originally conceived as generating ions from tissue vaporization in electrosurgery before transporting the ions through heated, flexible PTFE tubing to an MS instrument (6). (chromatographyonline.com)

Electron impact has remained the most widely used method of ionization in mass spectrometry. (britannica.com)
The impact of the electrons on the molecule (M) causes the ejection of an electron from the molecule to form a positively charged ion … Since the Alexander survey was published nearly 20 years ago,1 organic chemistry educators have continued to focus on this topic. (acadiasi.ro)
Gas Chromatography: for Mass Spectrometry, Flame Ionisation, Electron Capture and Thermal Conductivity. (1stdirectory.co.uk)
For the data sets used in this study, known mass differences are detected at electron mass ac- curacy or better. (lu.se)

Tradespace analysis is performed for two popular standoff detection methods: longwave infrared hyperspectral imaging and deep-UV Raman spectroscopy. (mit.edu)
More complex NMR methods: recording techniques, application of exchange phenomena, double resonance, spin-lattice relaxation, nuclear Overhauser effect, applications of experimental 2d and multipulse NMR spectroscopy, shift reagents. (ethz.ch)
In the present study, a method to discriminate red seal inks using Raman microscopy and Fourier transform infrared (FT-IR) spectroscopy was developed. (spectroscopyonline.com)
Spectral methods, especially infrared (IR) and Raman spectroscopy, can cover the shortages of the chromatographic and MS methods. (spectroscopyonline.com)
Recovered EPS was analyzed by Fourier-transform infrared spectroscopy and subjected to gas chromatography-mass spectrometry after cleavage and derivatization steps. (bvsalud.org)
The Seetohul group is involved in developing methods for the study of novel psychoactive substances, and the application of liquid phase broadband cavity enhanced absorption spectroscopy to analytical, biological and bio-analytical samples. (ntu.ac.uk)
The ion at m/z 28 corresponds to [M-16]+, and therefore indicates [M-O]+. Take a quick interactive quiz on the concepts in Identifying Organic Molecules Using Spectroscopy: Practice Problems or print the worksheet to practice offline. (acadiasi.ro)
The first three focus on infrared spectroscopy, mass spectrometry, and 1D NMR spectroscopy. (acadiasi.ro)
Isotope B is 35 amu and is 25% of X. The videos below will take you through the basic concepts, followed by a step-by-step breakdown of how to solve individual problems, with examples, for NMR, IR, and Mass Spectroscopy C7H14O Throughout these 50 years, this book has undergone many editions and remained one of the most popular textbooks on organic spectroscopy for chemistry undergraduates. (acadiasi.ro)
Inductively Coupled Plasma - Mass Spectroscopy (ICP-MS): this technique enables the analysis of more than 70 elements (metallic and non-metallic) from low ppt to high ppm in solution. (1stdirectory.co.uk)

Mass Spectrometry: A Textbook. (wikipedia.org)
J. H. Beynon in his textbook Mass Spectrometry and its Applications to Organic Chemistry writes "'resolution' and 'resolving power' have been used a great deal in the above discussion. (lsu.edu)
K. Biemann in his textbook Mass Spectrometry: Organic Chemical Applications , states that "the term resolution is used in different ways - Throughout this book resolution will be considered as M/ Δ M " (Biemann 1962). (lsu.edu)
Click on cover to order "Mass Spectrometry - A Textbook", 3rd edition. (acadiasi.ro)
Bezug Ã¼ber die Springer-Website, The problems and solutions websites supporting the 1st and 2nd editions of "Mass Spectrometry - A Textbook" have been conserved for the benefit of thousands of readers. (acadiasi.ro)

High resolution indicating better peak separation is also used in ion mobility spectrometry. (wikipedia.org)
There are several ways to define the minimum peak separation ΔM in mass spectrometry, therefore it is important to report the method used to determine mass resolution when reporting its value. (wikipedia.org)
Chromatographic separation of 25(OH)D(2) and 25(OH)D(3) was achieved after adding deuterated Delta(9)-tetrahydrocannabinol (D(9)-THC-D(3)) and organic extraction. (nih.gov)
The mass spectrometers used in ICP-MS range from relatively cheap quadrupoles with single mass number separation to high-resolution mass spectrometers capable of separating nearly identical masses. (elgalabwater.com)
This course is based on the knowledge from analytical chemistry I. Separation methods are included. (ethz.ch)
Separation methods: S. Ahuja (Ed.), Chromatography and Separation Science, Volume 4 of series 'Separation Science and Technology', Elsevier Academic Press, San Diego, 2003. (ethz.ch)
Combining mass spectrometry with separation techniques such as HPLC or CE can improve the accuracy and sensitivity of amino acid analysis. (pharmiweb.com)
The degree to which the peaks are resolved can be quantified using the peak width or the separation between two peaks and is represented by Δ(m/z) where m/z is the mass-to-charge ratio. (lsu.edu)
The Li group focuses on using microfluidics to develop separation methods, including those based on capillary electrophoresis. (ntu.ac.uk)

EA of organic species can be performed on organic/inorganic mixtures. (nasa.gov)
The method can effectively identify the pigments used in the inks, but it cannot analyze the polymers, additives, and inorganic pigments. (spectroscopyonline.com)
They are fast, accurate, nondestructive, and suitable for both organic and inorganic substance analysis. (spectroscopyonline.com)
This technique is widely used for organic and inorganic materials. (1stdirectory.co.uk)

Mass spectrometers are at the forefront of chemical analysis for small and large molecules, oceanic and interplanetary studies, forensic analysis, and clinical investigations. (purdue.edu)
Commercial benchtop mass spectrometers are restricted to primary and satellite labs because they are heavy, expensive, consume significant amounts of power and are not [physically] robust. (purdue.edu)
Miniature mass spectrometers mitigate these concerns while sacrificing some analytical performance. (purdue.edu)
Notwithstanding, miniature ion trap mass spectrometers such as the Mini 12, excel in chemical analysis because it has the same scan functions as its full-size counterpart allowing for qualitative and quantitative analysis in the lab and in the field. (purdue.edu)
The development of minimalistic ionization techniques known as ambient ionization has helped to encourage the removal of miniature mass spectrometers from the typical lab confines, to the field. (purdue.edu)

Ionisation modes include electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI). (lu.se)

Computational methods for mass spectrometry proteomics. (wikipedia.org)
In proteomics, high throughput approaches using mass spectrometry have be- come widely used. (lu.se)

Mass spectrometry: principles and applications. (wikipedia.org)
Chapters on mass spectrometry outline the principles of MS and explain modern ionisation techniques, giving nice descriptions of, for example, quadrupole and linear ion trap analysers, time of flight detectors, ion cyclotron resonance, ion mobility mass analysers. (chemistryworld.com)
The course covers the basics, principles and limitations for the most common methods for multivariate statistics (analysis of variance, principal component analysis and partial least squares regression), experimental design (super-saturated and factorial designs) and method validation with a focus on practical use. (lu.se)

Interpretation of mass spectra. (wikipedia.org)
The subsequently acquired mass spectra are then matched against a library of reference spectra. (technologynetworks.com)
Some materials, such as plastic, are more susceptible to minor variations in the surface, which can cause mass shifts in the spectra and require additional calibration spots. (technologynetworks.com)
In his book Mass Spectra and Isotopes , Aston defines resolving power as M/ Δ M (Aston 1933). (lsu.edu)
The method's focus is to globally detect mass differences, not to assign peptide sequences or modifications to individual spectra. (lu.se)

An LC-MS/MS SCIEX API4000 instrument, furnished with a positive electrospray ionization source and HPLC of Shimadzu, consisted of an SIL-HTC autosampler, dual pump, and column oven, which were utilized in the present work. (japsonline.com)

HPLC-MS . High pressure liquid chromatography coupled with mass spectrometry is a powerful method which we also routinely use for identity and purity checking. (pharmaceuticalsteroids.com)
Learn to capitalize on the advantages of both core-shell and thermally modified fully porous stationary phase media to expand the options for HPLC and UHPLC method development. (phenomenex.blog)
High performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) method development options can be extended significantly by tapping into the distinct advantages of core-shell and fully porous particles. (phenomenex.blog)
HPLC can be combined with various detection methods, such as UV absorption or fluorescence, to improve the accuracy of the analysis. (pharmiweb.com)
IEC, HPLC or CE) and detection methods described above to identify and quantify amino acids in protein samples. (pharmiweb.com)

Rather, the intention is to identify well-established methods that are used as the standard methods of analysis. (cdc.gov)
We present a new elemental analysis (EA) technique for organic species (CHNO) that allows fast on-line analysis (10 s) and reduces the required sample size to ∼1 ng, ∼6 orders of magnitude less than standard techniques. (nasa.gov)
This strategy has been successfully from large groupings of organisms, electrospray ionization used with consensus 16S ribosomal RNA primers for deter- mass spectrometry for accurate mass measurements of PCR products, and base composition signature analysis to mining bacterial diversity, both in environmental samples identify organisms in a sample. (cdc.gov)
Thereby, the method is applicable for the analysis of different types of bio-samples having amprenavir and can perform the bioavailability, bioequivalence, and forensic studies. (japsonline.com)
The environmental mass spectrometry laboratory has over 30 years of experience in the analysis of soil and sediments, and gas samples. (ncl.ac.uk)
The environmental mass spectrometry laboratory can perform both routine and bespoke GC and GC-MS analysis with integrated liquid and pyrolysis autosamplers, and gas sampling valves. (ncl.ac.uk)
This makes the method well suited for molecular weight determinations and mixture analysis. (rush.edu)
MALDI is a soft ionization approach used in mass spectrometry (MS) that allows the analysis of biomolecules (such as DNA, ribosomal proteins, peptides and sugars) and large organic molecules (such as polymers and other macromolecules). (technologynetworks.com)
Individual organic ligands, isolated from microbial cultures or biosynthesized through genomics, can be structurally characterized via NMR and tandem MS analysis, but this is tedious and time-consuming. (frontiersin.org)
In addition, attendance in the lecture 529-0289-00 'Instrumental analysis of organic compounts' (4th semester) is recommended. (ethz.ch)
Combined application of spectroscopic methods for structure determination, and practical application of element analysis. (ethz.ch)
This video clip demonstrates the collection of raw wastewater samples from the utility/maintenance hole using an auto/grab-sampler for the analysis of organics. (murraystate.edu)
thus, this method would be helpful for ink analysis in the forensic, drawing, and cultural heritage fields. (spectroscopyonline.com)
This practical limitation has caused method development to look toward onsite residual collection for later analysis (bringing vestiges of sample closer to the MS) or instrument miniaturization for portability (bringing the mass analyzer closer to sample). (chromatographyonline.com)
The research team, based mainly in Basel, Switzerland, said its novel secondary electrospray ionization-high resolution mass spectrometry (SESI-HRMS) platform allowed for headspace analysis of both immature and activated DCs in real time. (chromatographyonline.com)
This X-ray technique is a non-destructive method of analysis used to identify diverse crystalline phases in metallurgical coal, combustion residues, catalysts, etc. (canada.ca)
Analytical Chemistry at NTU includes both theoretical and applied research in areas such as Mass Spectrometry, the Analytical Toxicology of "new" psychoactive drugs, environmental analysis, and fundamental measurement science applied to chemistry. (ntu.ac.uk)
The Kilgour group focuses on developing advanced mass spectrometry solutions in areas such as biomedical research, environmental analysis and security applications. (ntu.ac.uk)
Compared to a classical hydrophobic surface, it leads to an improvement of the microfluidic actuation (both in terms of minimal applied voltage threshold and droplet speed) and it allows a matrix free LDI-MS analysis of very low concentration of peptides sample (down to fm/µL) through a rapid and simple protocol (without addition of any organic matrix) [3-6]. (science24.com)

Mass Spectrometry: Organic Chemical Applications. (wikipedia.org)

Some mass spectrometrists use the definition that is similar to definitions used in some other fields of physics and chemistry. (wikipedia.org)
Journal of Organic and Pharmaceutical Chemistry» was begun to publish in 2003 and is regarded as assignee of «Fìzìologìčno aktivnì rečovini» journal that was founded in 1966. (edu.ua)
The work of the group sits on the inter-disciplinary boundaries of chemistry , applied physics , applied mathematics , bio-analytical methods , and social science . (ntu.ac.uk)
Dr Warren Cross's research involves the modelling of chemical reactions, especially organic chemistry transformations involving transition metal catalysis. (ntu.ac.uk)
1st Edition in English The M + 1 peak has an intensity of 13.2, and the M + 2 peak has an intensity … Organic Chemistry Questions The Covalent Bond 1. (acadiasi.ro)
Institute of Organic Chemistry Use the IR Correlation Table. (acadiasi.ro)

In contrast to RP-LC, gradient elution HILIC begins with a low-polarity organic solvent and elutes polar analytes by increasing the polar aqueous content [ 13 ]. (springer.com)
Gilson Inc.). Samples were eluted from the SPE plate with an organic elution buffer containing ascorbic acid and analyzed overnight by LC-MS/MS in positive ion mode using electrospray ionization on an AB Sciex 5500 triple-quadrupole MS system (Applied Biosystems) coupled to a HP1200C LC system (Agilent Technologies). (cdc.gov)
The mobile phase, typically a gradient of water and organic solvent, facilitates the elution of amino acids from the column. (pharmiweb.com)

In addition to PCBs, these individuals were likely simultaneously exposed to other persistent organic pollutants including per and polyfluoroalkyl substances (PFAS), which are an emerging class of ubiquitous industrial chemicals that are measurable in the blood of most individuals and have themselves been linked increased risk of some non communicable diseases. (cdc.gov)
VARCLUS procedure was used to create hierarchical clusters between PFAS and other legacy persistent organic pollutants which may share similar exposure routes. (cdc.gov)
Zhao G, Xu Y, Han G, Ling B. Biotransfer of persistent organic pollutants from a large site in China used for the disassembly of electronic and electrical waste. (who.int)

Culturing methods enabled the determination of a number of viable microorganisms from different microbial groups and their isolation for potential future applications in specific cheese starter cultures. (who.int)

The literature on amprenavir unveiled that there are few analytical procedures available for the estimation of drug in API and dosage forms on liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) with more retention times. (japsonline.com)
Many techniques including thin-layer chromatography (TLC) (5), gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS) (6-10) have been used to classify the samples. (spectroscopyonline.com)

Ion mobility spectrometry. (wikipedia.org)

Please create your bookmark, if you are interested in learning about mass spectrometry, mass spectral interpretation, instrumentation, and the full range of ionization methods. (acadiasi.ro)

EA was applied to organic mixtures and ambient aerosols (sampled at 20 s from aircraft). (nasa.gov)

The major advantages of this method are its highly sensitivity, selectivity, and reliability for chemical hazard characterization in a complex mixture. (cdc.gov)
The prevalence of mass spectrometry in every corner of science is due to its high selectivity and sensitivity, wide chemical scope and to its adaptable nature. (purdue.edu)
Alkyl nitrates exhibit a moderate affinity towards NO + ionization leading to detection units of few hundreds of ppt and the highest sensitivity in H 3 O + mode was obtained for the water adducts signals. (copernicus.org)

Electrochemical techniques like adsorptive cathodic stripping voltammetry with competitive ligand equilibration (ACSV-CLE) can determine total concentrations of marine organic ligands and their conditional binding constants for specific metals, but cannot identify them. (frontiersin.org)
The Müller laboratory has more recently integrated spray-based and plasma-based ionization techniques into a handheld probe, using flexible 60 cm polyetheretherketone (PEEK) or fluorinated ethylene propylene (FEP) tubing (5). (chromatographyonline.com)
Along with in-house-developed test methods, the Characterization Laboratory offers a range of analytical techniques from the following standards committees: the American Society for Testing and Materials (ASTM) , the Canadian General Standards Board (CGSB) , and the International Organization for Standardization (ISO) . (canada.ca)
For the thermal decomposition of organic matter different pyrolysis techniques are applied. (geo-x.net)
To this end database search engines were rapidly developed after the introduction of ionization techniques for biological mass spectrometry [1-5]. (lu.se)

A highly sensitive, selective, and reliable analytical method has been developed and validated for characterization of asphalt fume generated under simulated road paving conditions. (cdc.gov)
The Characterization Laboratory supports Natural Resources Canada's energy policy through analytical method development for alternative fuels research and advanced fossil fuels. (canada.ca)

Common derivatization methods include using reagents like dansyl chloride, phenyl isothiocyanate (PITC), or 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC). (pharmiweb.com)

They are used in combination with different gas chromatographic methods such as gas chromatography, gas chromatography mass spectrometry and gas chromatography flame ionization detection. (geo-x.net)

A new analytical method to aid in the understanding of the organic carbon (OC) phase of particulate matter (PM) from advanced compression ignition (ACI) operating modes, is presented. (sae.org)
A NIOSH-certified CBRN PAPR with a loose-fitting face-piece, hood, or helmet and a filter or a combination organic vapor, acid gas, and particulate cartridge/filter combination or a continuous flow respirator for air levels greater than AEGL-1. (cdc.gov)

A study was conducted to investigate the effects of sludge stabilization methods on the production of priority pollutants and chlorinated organics. (epa.gov)

Direct-current sources were widely used during the first decades of mass spectrography. (britannica.com)

Overall this text is more comprehensive and more detailed in introductory descriptions than the classic text in the area - Spectroscopic methods in organic synthesis by Williams and Fleming. (chemistryworld.com)

Total organic matter of the asphalt fume was quantified over the 5 exposure days. (cdc.gov)
Elemental ratios for the total organic mass, such as oxygen/carbon (O/C), hydrogen/carbon (H/C), and nitrogen/carbon (N/C), in addition to the organic mass to organic carbon ratio (OM/OC), can be determined. (nasa.gov)
Results showed that sludge processed by the Purifax process at chlorine dosages normally used in processing wastewater sludges contains 2 to>14 times the total organic chlorine in raw sludge. (epa.gov)
More than 94 percent of the total organic chlorine is insoluble, and about 97 percent of that is associated with the cake. (epa.gov)

This use is also implied by the term "high-resolution mass spectrometry. (wikipedia.org)
It has been shown that hydroxyl and ketonitrates have a high affinity towards NO + , leading to the formation of an adduct that allows the easy identification of the organic nitrate (R) from the R-NO + ion signal. (copernicus.org)
Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. (rush.edu)
High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures. (rush.edu)
Fruit residues are attractive substrates for the production of bacterial polyhydroxyalkanoates due to the high contents of fermentable sugars and the fast, simple, and efficient pretreatment methods required. (bvsalud.org)
Researchers said they have devised a novel setup using a secondary electrospray ionization-high resolution mass spectrometry (SESI-HRMS) platform to detect bacterial cultures in cells that are vital to immune and memory functions. (chromatographyonline.com)
The Mass Distance Fin- gerprint is calculated from high accuracy measured peptide masses. (lu.se)
These extracts showed a high antioxidant capacity by the method of DPPH, -carotene, and nitric oxide. (bvsalud.org)

2019). Under gas-particle equilibrium, nearly all ( ≈ 100 %) LVOCs partition into the particle phase in the presence of ambient aerosol mass loadings. (copernicus.org)
Although ambient sampling and ionization methods continue to diversify, most systems position the ion source, analyte, and MS inlet within centimeters or less of one another. (chromatographyonline.com)

With the evolution of toxic chemicals continuing to progress, developing methods for the destruction of chemical warfare agents (CWAs) has become an increasingly important research topic. (preprints.org)

Performance is optimized by tailoring the ionization method (APCI/ESI), de-clustering potentials, and collision energies for each specific analyte. (mit.edu)
La méthode est basée sur la technique d'échantillonnage direct de l'air couplée avec la spectrométrie de masse en tandem utilisant une source d'ionisation chimique à pression atmosphérique (APCI-MS/MS directe). (umontreal.ca)

Metal-organic frameworks (MOFs) are a class of porous crystalline solids that have sparked interest in this area. (preprints.org)
Metal-organic frameworks (MOFs) have raised a few eyebrows for their permanent 14 porosity, precise tunability, and lasting stability. (preprints.org)
Dr Addicoat's research is in the development and application of computational approaches to determine the structure and properties of combinatorially complex materials, in particular molecular framework materials (such as Metal Organic Frameworks and Covalent Organic Frameworks) and ionic liquids. (ntu.ac.uk)

Organic vapors with sufficiently low volatility can condense onto existing particles or form new particles (Hallquist et al. (copernicus.org)

Both insoluble and soluble forms of organic chlorine increase with chlorine dosage. (epa.gov)

Anatomy5

Organisms5

Chemicals and Drugs78

Analytical, Diagnostic and Therapeutic Techniques and Equipment72

Phenomena and Processes43

Disciplines and Occupations10

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture3

Information Science8

Health Care9

Tandem mass spectro8

Time-of-flight ma3

Laser desorption ionization mass spectrometry3

Electrospray ionization m3

Chromatography coupled to mass spectrometry1

Compounds22

Spectrometer12

Desorption5

Quantification1

Spectrometric4

Structure elucidation1

Ions12

Electron4

Spectroscopy10

Textbook5

Separation9

Inorganic4

Spectrometers5

Atmospheric1

Proteomics2

Principles3

Spectra5

Positive electrospray ionization1

HPLC5

Analysis19

Chemical Applications1

Chemistry6

Elution3

Persistent organic po3

Microbial1

Liquid2

Mobility1

Spectral1

Aerosols1

Sensitivity3

Techniques5

Characterization2

Derivatization1

Flame1

Particulate2

Pollutants1

Widely1

Synthesis1

Total organic4

High8

Ambient2

Increasingly1

APCI2

Frameworks3

Existing particles1

Soluble1