Involves human tissues fetal tissue research. Medical search. Frequent questions

The NIH is funding a $20 million program to "develop, demonstrate, and validate experimental models that do not rely on human fetal tissue from elective abortions. (chicagotribune.com)
NIH "has directed funding toward the development of alternative research methods that do not rely on human fetal tissue from elective abortions and I remain supportive of that effort. (chicagotribune.com)
In July, the Food and Drug Administration signed a $15,900 contract with Advanced Bioscience Resources, Inc. (ABR) to procure fetal tissues obtained from elective abortions. (catholicnewsagency.com)
The fetal tissues used in these experiments and research is obtained through abortions. (netrighttolife.org)
19] Under the Department's aegis, hospital ethics committees approved individual projects, but - contrary to the Polkinghorne Report (1989) - some members were involved in research and in providing abortions. (cmq.org.uk)
B19 has also been associated with fetal death (both spontaneous abortions and stillbirths), acute arthralgias and arthritis, and chronic anemia in immunodeficient patients (5-14). (cdc.gov)

[ 1 ] The human adult wound healing process can be divided into 3 or 4 distinct phases. (medscape.com)
These include 'adult' differentiated cells of the body (known as somatic cells, e.g. skin cells) and stem cells from a range of sources - embryonic, foetal, cord blood, and mature tissues. (eurostemcell.org)
My research interests focus mainly on stem cells (embryonic, 'adult' and fetal origins) and their applications in tissue engineering, particularly the osteoblast and bone tissue. (nottingham.ac.uk)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)

Organ trade (also known as the blood market) is the trading of human organs, tissues, or other body products, usually for transplantation. (wikipedia.org)
There is a worldwide shortage of organs available for transplantation, yet the commercial trade of human organs is illegal in all countries except Iran. (wikipedia.org)
Secretary Azar must put an immediate moratorium on funding for research using aborted baby organs and tissue purchased from the abortion industry," said Dannenfelser, who called for tax dollars to be diverted to "ethical alternatives" that have produced successful results in patients. (catholicnewsagency.com)
Cell therapies are treatments that use human cells, including stem cells, with the aim of restoring, maintaining, or improving the functioning of human tissues or organs. (eurostemcell.org)
My PhD focussed on investigating the distributions and possible functions of nitric oxide/nitric oxide synthases in the physiology and pathology of a variety of tissues and organs and I was fortunate enough to publish some of the first papers on the involvement of these molecules in human diseases, notably in the cardiovascular system. (nottingham.ac.uk)

The department also announced a "comprehensive review" of any research involving fetal tissue, and that it will be seeking "adequate alternatives" to avoid the use of human fetal tissue altogether. (catholicnewsagency.com)
At that time, the Department of Health and Human Services (HHS) said that it was seeking "adequate alternatives" to the use of fetal tissue altogether. (netrighttolife.org)
Altogether, these lesions resemble the 'cytopathic-inflammatory pathology pattern' proposed in the pathogenesis of Human polyomavirus-1-associated nephropathy in immunocompromised people and kidney allograft recipients. (cdc.gov)

In August of 2003, Australia passed legislation that ensures consumers have the right to know when human embryos, human embryonic stem cells or materials derived from embryos or stem cells are used in the manufacture or testing of pharmaceuticals. (consciencelaws.org)
b) Any new prescription or non-prescription drug or medical treatment that will use human fetal or embryonic tissue, cell lines, DNA or components from procured abortion or in-vitro fertilized embryos that have been donated or otherwise produced or reproduced in research. (consciencelaws.org)
e) Any person or patient who is the recipient of a prescription or non-prescription drug, vaccination or medical procedure that would involve the use of human fetal or embryonic tissue, cell lines, DNA or components from procured abortion or in-vitro fertilized embryos that have been donated or otherwise produced or reproduced sexually or asexually in research. (consciencelaws.org)
For example, certain research may require using embryonic/fetal tissue that must be fresh and not frozen or in any way not normal and tissues from miscarried embryos/fetuses do not meet these criteria. (ewtn.com)
The Instruction 'Donum Vitae' formulated the general principle which must be observed in these cases: 'The corpses of human embryos and fetuses, whether they have been deliberately aborted or not, must be respected just as the remains of other human beings. (ewtn.com)
According to this passage, the use of such "biological material" would be ethically permissible provided there is a clear separation between those who produce, freeze, and cause the death of embryos and researchers involved in scientific experimentation. (ewtn.com)
Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)

Ending the use of fetal tissue by the National Institutes of Health has been a priority for anti-abortion activists, a core element of President Donald Trump's political base. (chicagotribune.com)
The Susan B. Anthony List, a group that works to elect lawmakers opposed to abortion, said in a statement that taxpayer funding ought to go to promoting alternatives to using fetal tissue in medical research. (chicagotribune.com)
The practice of conducting research using the body parts of children whose lives have been violently ended by abortion is abhorrent. (catholicnewsagency.com)
What should a conscientious pro-life person do if his research center agreed to use biological material obtained as a result of the intentional abortion of babies in their embryonic or fetal stages of life? (ewtn.com)
Following media scrutiny of the existing contract between the FDA and Advanced Bioscience Resources, which has admitted to the "upselling" of some fetal parts obtained through abortion, the contract was canceled and HHS announced that it would review all similar programs. (netrighttolife.org)
Francois Lafitte opened an abortion clinic in the 1960s,[8] becoming Chairman of BPAS (British Pregnancy Advisory Service) which supplied fetal material for research into pre-natal disability diagnosis. (cmq.org.uk)

It later emerged that human tissue, retained without consent in Medical Research Council banks since 1958, was used for experimentation, with fetal brain tissue grafted into the brains of adults with Parkinson's disease. (cmq.org.uk)

As a result, NIH froze procurement of new tissue. (chicagotribune.com)
After a recent review of a contract between Advanced Bioscience Resources, Inc. and the Food and Drug Administration to provide human fetal tissue to develop testing protocols, HHS was not sufficiently assured that the contract included the appropriate protections applicable to fetal tissue research or met all other procurement requirements," the statement read. (catholicnewsagency.com)
As a result, that contract has been terminated, and HHS is now conducting an audit of all acquisitions involving human fetal tissue to ensure conformity with procurement and human fetal tissue research laws and regulations. (catholicnewsagency.com)
In light of the serious unresolved questions uncovered by the investigative work of both the House and Senate panels, we are alarmed that the FDA has continued to award contracts to ABR for the procurement of human fetal tissue," the legislators wrote. (catholicnewsagency.com)

The government's own top medical scientist, NIH Director Francis Collins, said as recently as last December that he believes "there's strong evidence that scientific benefits come from fetal tissue research ," and that fetal tissue, rather than any alternatives, would "continue to be the mainstay" for certain types of research for the foreseeable future. (chicagotribune.com)

That test uses a sample of amniotic fluid (the liquid in the sac surrounding the baby) or tissue taken from the placenta (the organ that brings oxygen and nutrients to the baby). (medlineplus.gov)
Lead can cross the placenta and enter the developing fetal brain. (cdc.gov)

At this time I also began working with mouse and human embryonic stem cells resulting in the publication of some of the first papers describing the osteogenic differentiation of mouse ES and human cells in vitro and in vivo . (nottingham.ac.uk)
Noninvasive detection and imaging of molecular markers in live cardiomyocytes derived from human embryonic stem cells Biophysical Journal. (nottingham.ac.uk)

From 1999 onwards my research has been focused primarily on osteoblast biology and approaches to tissue engineer and model bone biology, pathology and repair. (nottingham.ac.uk)
Bone heats faster more than soft tissue, which in turn heats more than fluid. (thehealthyskeptic.org)
The risk of inducing thermal effects is greater in the second and third trimesters, when fetal bone is intercepted by the ultrasound beam and significant temperature increase can occur in the fetal brain. (thehealthyskeptic.org)
In the blood, absorbed lead is bound to erythrocytes and then is distributed initially to multiple soft tissues and eventually into bone. (cdc.gov)

Research Conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. (uky.edu)
We tested various specimens (blood, cerebrospinal fluid, intraocular fluid, serum, and tissues) from the organ donor and recipients by serology, RT-PCR, immunohistochemistry, metagenomic next-generation sequencing, and host gene expression, and conducted a traceback of blood transfusions received by the organ donor. (cdc.gov)

Today, fetal tissue is still making an impact, with clinical trials underway using cells from fetal tissue to treat conditions including Parkinson's disease, ALS, and spinal cord injury," said Doug Melton, co-director of Harvard's Stem Cell Institute and president of the International Society for Stem Cell Research. (chicagotribune.com)
These are at all stages of development from early preclinical research, as with a neural stem cell therapy being developed for Parkinson's Disease by Axontherapix S.L of Spain, through to products that are available to treat patients now such as Chondroselect ® , a cell therapy for repairing damaged tissue in knee joints produced by Belgian cell therapy firm TiGenix. (eurostemcell.org)
The National Institutes of Health informed UCSF it will not renew a contract to conduct research into therapies for various ailments, including AIDS and Parkinson's disease, over concerns about the project's use of fetal tissue. (netrighttolife.org)

By the fourth day, phagocytosis of contaminated tissues is well underway, and the processes of epithelization, collagen deposition, and maturation are occurring. (medscape.com)

Scientists around the country denounced the decision, saying that fetal tissue was critically needed for research on HIV vaccines, treatments that harness the body's immune system to battle cancer, and other health threats, including some to fetuses themselves. (chicagotribune.com)
On Wednesday, the administration also said it is not renewing an expiring contract with the University of California, San Francisco, that used fetal tissue to create a human-like immune system in mice for HIV research. (chicagotribune.com)
The mice would be injected with the tissues, causing them to develop an immune system similar to that of a human for the purposes of clinical testing. (catholicnewsagency.com)

It blocks important future research vital to the development of new therapies. (chicagotribune.com)
Biotech products include protein drugs made by genetically-engineered cell cultures, monoclonal antibodies (laboratory-made copies of a single human antibody, often for use in cancer treatment ) and, most recently, human cell-based therapies. (eurostemcell.org)
Companies face a choice between a range of human cell types to work with when developing new therapies. (eurostemcell.org)
These new therapies involve taking some of your blood stem cells and either adding new DNA to them or changing their existing DNA. (medlineplus.gov)

March for Life President Jeanne Mancini said in a statement Tuesday that, while she is thankful that HHS had ended the "horrific" contract with ABR, the move was "just a first step" and that the federal government continued to use fetal remains in experiments. (catholicnewsagency.com)

Excluded from this definition are in vitro studies that utilize human tissues that cannot be linked to a living individual. (uky.edu)

One study found brain hemorrhages in mouse pups exposed in womb to pulsed ultrasound at doses similar to those used on human babies. (thehealthyskeptic.org)
However, HIV/AIDs antiretroviral drugs sanctioned for use on fetal brain tissue had already been approved by the US Food and Drug Administration. (cmq.org.uk)
Recent infection with yellow fever virus was confirmed in all four organ recipients by identification of yellow fever virus RNA consistent with the 17D vaccine strain in brain tissue from one recipient and seroconversion after transplantation in three recipients. (cdc.gov)
And my luck was that I entered brain research at the time, in the late 1960s, when modern neuroscience was born, and in the labora- tory where a new groundbreaking microscopic technique, the Falck-Hillarp monoamine histofluorescence method, had just been developed. (lu.se)

This discussion typically centers on the sale of kidneys by living donors, since human beings are born with two kidneys but need only one to survive. (wikipedia.org)
The sonar beam can cause heating in the tissues beings scanned. (thehealthyskeptic.org)

Acoustic streaming involves a jet of fluid created by the ultrasound wave, which causes a mechanical shearing force at the cell surface. (thehealthyskeptic.org)
Background Meconium-stained amniotic fluid (MSAF) is considered an alarming sign of possible fetal compromise and it has recently been reported that neonatal outcome correlates with the degree of meconium thickness. (bvsalud.org)

Clinical Research. (uky.edu)
NIH defines human clinical research as research with human subjects that is: (1) Patient-Oriented Research. (uky.edu)
Patient-oriented research includes (a) mechanisms of human disease, (b) therapeutic interventions, (c) clinical studies, or (d) development of new technologies. (uky.edu)
Note: Studies falling under Exemption 4 for human subjects research are not considered clinical research by this definition. (uky.edu)
The NIH defines a clinical trial as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes. (uky.edu)
The term "prospectively assigned" refers to a pre-defined process (e.g., randomization) specified in an approved protocol that stipulates the assignment of research subjects (individually or in clusters) to one or more arms (e.g., intervention, placebo or other control) of the clinical trial. (uky.edu)

Paired donations address the problem of tissue compatibility in organ transplants. (wikipedia.org)

Fascinatingly, the young whippersnappers from the Gladyshev lab now reveal some fascinating insights into the dynamics and the mechanisms involved in the rejuvenation of DNA methylation profiles during the very early stages of mammalian embryogenesis. (epigenie.com)

I was also affiliated with the Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), part of the Centre for Biomolecular Sciences, which is now the Biodiscovery Institute. (nottingham.ac.uk)
My research continues to focus on stem cells and osteoblasts and in particular 3D cell culture models and microenvironments. (nottingham.ac.uk)
This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)
The protein protects tissue from inflammation when cells rupture. (lu.se)
AcouSort - a biotech company providing solutions for automated sample preparations involving biological cells or other organelles, using the technology of acoustophoresis. (lu.se)
In the fifth week of fetal development, neuroblastic cells migrate from the thoracic neural crest to form the sympathetic chains and preaortic ganglia. (medscape.com)
2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)

But research using fetal tissue has led to lifesaving advances , including development of vaccines for rubella and rabies and drugs to treat HIV. (chicagotribune.com)
Research (DHHS): "A systematic investigation, including research development, testing, and evaluation, designed to develop or contribute to generalizable knowledge. (uky.edu)
Though both animal and human studies have shown that temperature elevations can cause abnormal development and birth defects, so far human studies have not shown a direct causal relationship between diagnostic ultrasound exposure during pregnancy and adverse effects to the developing baby. (thehealthyskeptic.org)
While the effect of this force is not fully understood, research suggests that it may change cell permeability and have adverse effects on both early and late prenatal and postnatal development. (thehealthyskeptic.org)
Dr. Gardner has worked in integrated pest management, researched the presence of toxicants in human breast milk, analyzed the environmental impact statements of energy transportation development, evaluated the use of hazardous waste in recycled glass products, and developed applications for air permits and economic development funds. (ucsb.edu)
FUNDING: US Centers for Disease Control and Prevention (CDC), the Biomedical Advanced Research and Development Authority, and the CDC Epidemiology and Laboratory Capacity Cooperative Agreement for Infectious Diseases. (cdc.gov)

These countries all have strong existing infrastructures, including regulations and facilities, for biomedical research and commercialisation and so it is not surprising that they have also become 'hubs' for cell therapy within Europe. (eurostemcell.org)

The tissue was to be used in the creation of "humanized mice. (catholicnewsagency.com)
The work in the UCSF lab involves testing on what are known as "humanized mice" that have been implanted with tissues from fetal remains. (netrighttolife.org)
The non-renewal of the UCSF contract comes just over two months after the government canceled a significantly smaller contract between the Food and Drug Administration and Advanced Bioscience Resources, Inc. that also involved the creation of humanized mice. (netrighttolife.org)

No. 34 first identifies a common situation causing moral problems: "For scientific research and for the production of vaccines or other products, cell lines are at times used which are the result of an illicit intervention against the life or physical integrity of a human being. (ewtn.com)

WASHINGTON - The National Institutes of Health will not renew a contract with the University of California San Francisco (UCSF) over concerns about the project's use of fetal tissue. (netrighttolife.org)

The quandary is the following: Suppose that it is not possible to do the research proposed by using spontaneously aborted unborn babies who miscarry. (ewtn.com)

In order to encourage ethical research and protect the rights of all Americans as well as the citizens of foreign countries who use our products, the current method of labeling and informed consent must be amended. (consciencelaws.org)

The Health and Human Services Department said in a statement that government-funded research by universities that involves fetal tissue can continue for now, subject to additional scrutiny - although it also ended one major university project that used the tissue to test HIV treatments. (chicagotribune.com)
c) Any health care provider, researcher, technician or other person required to perform or assist in the administration or research of prescription or non-prescription drugs, vaccinations or medical treatments. (consciencelaws.org)
Part III of "Dignitas Personae" is called "New treatments which involve the manipulation of the embryo or human genetic patrimony. (ewtn.com)

However, it must be pointed out that all human epidemiologic studies were conducted with commercially available devices predating 1992 with acoustic outputs not exceeding an intensity of 94 mW/cm2. (thehealthyskeptic.org)

No. 35 points out a somewhat different situation - the precise one of concern to us - with its set of moral issues, stating: "A different situation is created when researchers use 'biological material' of illicit origin which has been produced apart from their research center or which has been obtained commercially. (ewtn.com)
The culmination of these biological processes results in the replacement of normal skin structures with fibroblastic mediated scar tissue. (medscape.com)
When modern sophisticated equipment is used at maximum operating settings for Doppler examinations, the acoustic outputs are sufficient to produce obvious biological effects, e.g. significant temperature increase in tissue or visible motion of particles due to radiation pressure streaming effects. (thehealthyskeptic.org)

Debricked - born out of a research project in 2018, Debricked wants to make it easier for companies to use open source securely. (lu.se)

2000). Children may also be exposed to lead brought into the home on the work clothes of adults whose work involves lead. (cdc.gov)

Early onset fetal growth restriction (FGR) is one of the main adverse pregnancy conditions, often associated with poor neonatal outcomes. (bvsalud.org)

One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)

g) Any Institutional Review Board (IRB), Hospital Ethics Committee (HEC) or other committee reviewing and/or recommending experimental or therapeutic research or medical provision of a prescription or non-prescription drug, vaccination, or medical procedure that would involve the use of aborted fetal or embryonic tissue, DNA, cell lines, components or parts. (consciencelaws.org)

Understanding the mechanisms involved in guiding at least under homeostatic or physiological conditions. (lu.se)

The letter raised concerns that ABR may have violated federal law concerning the sale of fetal remains. (catholicnewsagency.com)
The letter also called for an end to the use of fetal remains in scientific research. (catholicnewsagency.com)

ABR admitted to "upselling" certain fetal parts for a larger fee. (catholicnewsagency.com)

During normal pregnancy, increases in whole-body temperature of up to 4.5 degrees F (2.5 C) are presumed to be safe, and research suggests that elevations of tissue temperature up to 1.8 - 2.7 degrees F (1.0 to 1.5 C) caused by ultrasound are also safe. (thehealthyskeptic.org)
A recent study suggests that heating in late-pregnancy fetal tissues exposed to normal pulsed and continuous Doppler ultrasound may be higher than what is regarded as safe: 2.5 to 10.4 degrees F (1.4 - 5.8 C) respectively. (thehealthyskeptic.org)

The Department of Health and Human Services has announced the termination of a contract between the Food and Drug Administration and Advanced Bioscience Resources, Inc. The news comes after members of Congress and pro-life advocates expressed concern about the research goals of the experiment. (catholicnewsagency.com)

I returned full time to Imperial College in 1999 to take up a lectureship in cell biology and tissue engineering and was also actively involved in establishing the Tissue Engineering Centre. (nottingham.ac.uk)

METHODS: From Nov 7, 2021, to Feb 24, 2022, we conducted a public health investigation involving 15 agencies and medical centres in the USA. (cdc.gov)

My research career has been unadventurous in the sense that I have remained at the same institution, Lund University in Sweden, where I started my medical studies in 1964. (lu.se)

Lead is cleared from the blood and soft tissues with a half-life of 1 to 2 months and more slowly from the skeleton, with a half-life of years to decades. (cdc.gov)
A1M Pharma - Professors of Medicine Bo Åkerström and Stefan Hansson discovered that free fetal hemoglobin is harmful if it leaks into the mother's blood circulation. (lu.se)

For a few years, I entertained the possibility to go abroad on a postdoc, but the support and the laboratory resources provided by my mentor Bengt Falck made it less attractive to leave Lund, particularly since Bengt generously gave me the freedom to develop my own ideas and pursue my own research. (lu.se)

Abdominal CT scan demonstrating left suprarenal mass of soft tissue attenuation representing a paraganglioma. (medscape.com)

But the scientific consensus is there is no adequate substitute for fetal tissues in some research areas. (chicagotribune.com)

The panel was strongly encouraged to avoid discussing the merits of hair analysis for drug testing or nutritional screening, unless such discussions involved a technical point that was directly applicable to environmental exposure assessment at hazardous waste sites. (cdc.gov)

The decision not to renew the contract follows what the federal government called in a September statement a "comprehensive review" over the funding of research involving the use of fetal tissue. (netrighttolife.org)

In this article I'm going to review evidence on the safety of routine ultrasound and Doppler scanning, and make recommendations based on that research. (thehealthyskeptic.org)
There is no consensus on the significance of cavitation effects in human fetal tissue, but some evidence suggests that mammalian tissue may contain microbubbles that are susceptible to cavitation effects. (thehealthyskeptic.org)
restorative research provides evidence for natural rejuvenation processes occurring at the epigenetic level during mammalian embryogenesis. (epigenie.com)

This 'material' is sometimes made available commercially or distributed freely to research centers by governmental agencies having this function under the law. (ewtn.com)

Last year, the administration announced a review of whether taxpayer dollars were being properly spent on fetal tissue research. (chicagotribune.com)

However, to date, BoPyV-1 has not been causally associated with pathology or disease in any animal species, including humans. (cdc.gov)

Priorities for future research are identified. (cdc.gov)

Anatomy38

Organisms12

Diseases15

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Psychiatry and Psychology7

Phenomena and Processes46

Disciplines and Occupations27

Anthropology, Education, Sociology and Social Phenomena16

Humanities13

Information Science17

Named Groups3

Health Care42

Geographicals2

Abortions6

Adult4

Organs5

Altogether3

Embryos7

Abortion6

Experimentation1

Procurement4

Alternatives1

Placenta2

Embryonic stem2

Bone4

Specimens2

Parkinson's3

Underway1

Immune system3

Therapies4

Experiments1

Vitro1

Brain4

Beings2

Fluid2

Clinical6

Organ1

Stages1

Cells7

Development6

Regulations1

Mice3

Vaccines1

National Instit1

Babies1

Ethical research1

Treatments3

Epidemiologic1

Biological3

20181

Adults1

Adverse1

Stem cell2

Therapeutic1

Mechanisms involved1

Remains2

Parts1

Normal2

Food and Drug Admin1

Biology1

Investigation1

Lund University1

Blood2

Develop1

Soft1

Scientific1

Applicable1

Comprehensive review1

Evidence3

Material1

Review1

Pathology1

Future1