• In contrast, regions of striatum and ventromedial prefrontal cortex exhibit activity characteristic of an involvement in value-based exploitative decision making. (nih.gov)
  • Decision Making - Science Friday audio discussion of the involvement of social emotion and ventromedial prefrontal cortex in decision making, social featuring Daniel Tranel and Scott Plous. (iaswww.com)
  • 19 Moreover, the dorsal anterior cingulate cortex (ACC), rostral ACC and ventromedial prefrontal cortex, which are involved in the experience and regulation of emotion, have repeatedly been observed to be less activated in patients with PTSD than in controls who have a history of trauma but not PTSD. (psychiatrictimes.com)
  • For this purpose, male Wistar rats will submitted to a surgery for the implant of a radiotelemetric probe into the abdominal aorta for monitoring autonomic responses, and after, cannulae guide will be stereotaxically implanted bilaterally in in the infralimbic (IL) or prelimbic (PL) regions of the ventromedial prefrontal cortex (vmPFC) of rodents for drug administration. (fapesp.br)
  • RESSTEL, LEONARDO B. M. . Differential modulation of the contextual conditioned emotional response by CB1 and TRPV1 receptors in the ventromedial prefrontal cortex: Possible involvement of NMDA/nitric oxide-related mechanisms . (fapesp.br)
  • Historically, the DLPFC was defined by its connection to: the superior temporal cortex, the posterior parietal cortex, the anterior and posterior cingulate, the premotor cortex, the retrosplenial cortex, and the neocerebellum. (wikipedia.org)
  • Autobiographical planning was found to engage the default network, including medial-temporal lobe and midline structures, and executive control regions in lateral pFC and parietal cortex and caudate. (mit.edu)
  • Involvement of both prefrontal and inferior parietal cortex in dual-task performance. (bvsalud.org)
  • Studies using neuroimaging techniques also hint at the involvement of the parietal cortex and certain subcortical areas. (citi.io)
  • Cerebellar projections are directed into a variety of associative locations in the prefrontal and parietal cortex. (bloghalt.com)
  • Yet, high-anxious individuals fail to recruit FPl during emotional action control, relying instead on dorsolateral and medial prefrontal areas. (nature.com)
  • rTMS was delivered to the left ventrolateral (VLPFC) or dorsolateral prefrontal cortex (DLPFC). (essex.ac.uk)
  • The dorsolateral prefrontal cortex (DLPFC or DL-PFC) is an area in the prefrontal cortex of the primate brain. (wikipedia.org)
  • Thus, damage to the dorsolateral prefrontal cortex does not impair recognition memory. (wikipedia.org)
  • When HES were compared to 22 healthy young subjects, widespread decrease in metabolism was observed in bilateral medial prefrontal areas including anterior cingulate cortices, in dorsolateral prefrontal areas, in left lateral premotor area, in Broca's area, and in left insula. (nih.gov)
  • When comparing FTD to HS, glucose uptake was primarily reduced in dorsolateral and ventrolateral prefrontal cortices and in frontopolar and anterior cingulate regions. (nih.gov)
  • Additionally, the anterior cingulate cortex and dorsolateral prefrontal cortex were active. (bloghalt.com)
  • Volumetric magnetic resonance imaging studies have shown that children with TS have larger dorsolateral prefrontal regions as well as increased cortical white matter in the right frontal lobe. (medscape.com)
  • Although the origin of this failure is unclear, one candidate system involves control of emotional actions, coordinated through lateral frontopolar cortex (FPl) via amygdala and sensorimotor connections. (nature.com)
  • Whole-brain analyses showed post-treatment decreases in cerebral blood flow (CBF) in the temporal cortex, including the amygdala, which correlated with reduced depressive symptoms. (medscape.com)
  • The amygdala is connected with the prefrontal cortex, an area involved with our highest intellectual properties, and receives sensory inputs from it all the time. (typepad.com)
  • Deduction activated areas near right brain homologues of left language areas in middle temporal lobe, inferior frontal cortex and basal ganglia, as well as right amygdala, but not spatial visual areas. (neurotransmitter.net)
  • The DLPFC has connections with the orbitofrontal cortex, as well as the thalamus, parts of the basal ganglia (specifically, the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex (including posterior temporal, parietal, and occipital areas). (wikipedia.org)
  • Recent lesion-based research studies have defined the roles of two different parts of the primate PFC - the orbitofrontal cortex (OFC) and the ventral lateral frontal cortex (VLFC) - and their subdivisions in evaluating each of these factors and in mediating credit assignment during reward-based decision-making. (nature.com)
  • Meyer, H. C. & Bucci, D. J. Imbalanced activity in the orbitofrontal cortex and nucleus accumbens impairs behavioral inhibition. (nature.com)
  • Wallis, J. D. Cross-species studies of orbitofrontal cortex and value-based decision-making. (nature.com)
  • Furthermore, using this characterization to classify decisions as exploratory or exploitative, we employ functional magnetic resonance imaging to show that the frontopolar cortex and intraparietal sulcus are preferentially active during exploratory decisions. (nih.gov)
  • Braver TS, Bongiolatti SR (2002) The role of frontopolar cortex in subgoal processing during working memory. (springer.com)
  • Christoff K, Gabrieli JDE (2000) The frontopolar cortex and human cognition: evidence for a rostrocaudal hierarchical organization within the human prefrontal cortex. (springer.com)
  • Value, search, persistence and model updating in anterior cingulate cortex. (nature.com)
  • Learned predictions of error likelihood in the anterior cingulate cortex. (wustl.edu)
  • Brain imaging revealed that the rear (posterior) part of the lateral prefrontal cortex processes an individual's current situation, while the front (anterior) prepares for future situations. (elifesciences.org)
  • We anticipate conducting what I'll call 'more fundamental' studies of the response properties to graded illumination in the frontal cortex of humans so as to gain a fuller understanding of the range of frontal cortical responses to light," he commented. (medicalnewstoday.com)
  • Of particular interest is whether the lateral prefrontal cortex has a hierarchical organization wherein a region coordinates the roles of other regions, much like the chief executive of a company. (elifesciences.org)
  • Cognition and control in schizophrenia: A computational model of dopamine and prefrontal function. (wustl.edu)
  • Finally, studying how these interactions are altered in disorders such as schizophrenia, where the lateral prefrontal cortex shows abnormal activity, might pave the way for more effective treatments. (elifesciences.org)
  • Ehlis AC, Reif A, Herrmann MJ, Lesch KP, Fallgatter AJ (2007) Impact of catechol- O -methyltransferase on prefrontal brain functioning in schizophrenia spectrum disorders. (springer.com)
  • Here, we investigate these using a novel multiarea spiking neural network model of prefrontal cortex (PFC) and two parietotemporal cortical areas based on macaque data. (eneuro.org)
  • Our cortex model is constrained by relevant experimental data about cortical neurons, synapses, modularity, and connectivity. (eneuro.org)
  • D'Esposito and Postle, 2015 ), there is accumulated evidence for the involvement of other cortical regions, particularly parietotemporal networks associated with long-term memory (LTM) correlates. (eneuro.org)
  • Immunoblot analyses with anti-active mitogen-activated protein kinases (MAP-Ks) revealed that D1 receptors, D2 receptors, group I mGluRs, and group II mGluRs all contribute to MAP-K activation in prefrontal cortex, and that combined activation of dopamine receptors and mGluRs synergistically or additively activate MAP-Ks. (jneurosci.org)
  • Dopamine receptors in the prefrontal cortex may play a role, as they are involved in the processing of both fear- and reward-related memories. (sfn.org)
  • Steven Laviolette and colleagues examined the involvement of two dopamine receptors in the recall of a traumatic experience - a footshock - and subsequent preference for morphine. (sfn.org)
  • The role of medial prefrontal cortex mineralocorticoid and glucocorticoid receptors in the process of extinction of aversive memory in rats submitted to acute stress. (fapesp.br)
  • The aim of the present study is to investigate the role of acute stress and mineralocorticoid and glucocorticoid receptors present in the prefrontal cortex in the memory extinction learning. (fapesp.br)
  • Continuing, The Forebrain: Development, Physiology and Functions aims to show the existence of specific neuronal populations in basal forebrain linking with specific sensory, motor and prefrontal cortices. (novapublishers.com)
  • The DLPFC is known for its involvement in the executive functions, which is an umbrella term for the management of cognitive processes, including working memory, cognitive flexibility, and planning. (wikipedia.org)
  • Nevertheless, if two items must be compared from memory, the involvement of DLPFC is required. (wikipedia.org)
  • This widespread, abnormal activity of interrelated circuits shows extensive involvement of the sensorimotor, language, and paralimbic regions. (medscape.com)
  • Painful burning feet is caused by a sensory neuropathy with small fiber involvement in more than 90% of cases. (medscape.com)
  • Most of these diseases are accompanied by cognitive and executive-function deficits associated with prefrontal dysfunctions. (frontiersin.org)
  • Goldman-Rakic's recent research at Yale focused on the role of signaling molecules and their involvement in a number of brain disorders and cognitive deficits. (yale.edu)
  • In the 1970's, she found that the loss of dopamine in the prefrontal cortex produced profound working memory deficits. (yale.edu)
  • These data indicate that reelin is necessary for the correct maturation and refinement of GABAergic synaptic circuits in the postnatal PFC and therefore provide a mechanism for altered E/I balance of prefrontal circuits associated with psychiatric disorders. (frontiersin.org)
  • In closing, the authors discuss the putative involvement of Reelin signal in motor-related impairments observed in neurological diseases, including lissencephaly, psychiatric disorders and brain injuries. (novapublishers.com)
  • The Morris water maze is a well-accepted tool used to document the involvement of the hippocampus in a behavioral task. (jove.com)
  • In 75-80% of patients, symptoms begin with limb involvement. (medscape.com)
  • Some patients will show cognitive and behavioral changes due to involvement of the prefrontal cortex. (medscape.com)
  • Patients with pure small fiber involvement display normal large fiber function. (medscape.com)
  • In appetitive choice, substantial experimental evidence, underpinned by computational reinforcement learning (RL) theory, indicates that a dopaminergic, striatal and medial prefrontal network mediates learning to exploit. (nih.gov)
  • Recent behavioral studies indicate distinct patterns of performance and suggest differential hemispheric involvement for insight and noninsight solutions. (neurotransmitter.net)
  • Additionally, five regions that responded to light activation "have clear involvement in cognitive and emotional processes. (medicalnewstoday.com)
  • Therefore, Nee and D'Esposito set out to map how the lateral prefrontal cortex is organized, and how its different regions communicate with each other to support complex cognition. (elifesciences.org)
  • Future experiments should test whether the interactions observed between the different regions of the lateral prefrontal cortex are essential for complex planning and thinking. (elifesciences.org)
  • The results suggest that abnormal dopamine signals in the prefrontal cortex may underlie the ability of traumatic memories to predispose individuals to addiction by increasing their sensitivity to the rewarding effects of drugs such as opioids. (sfn.org)
  • Research has consistently shown significant prefrontal activation during tasks in typically developed children, but this activation may be abnormal in children with developmental disorders. (frontiersin.org)