• Infants with congenital Zika syndrome might have vision-threatening fundus abnormalities. (medscape.com)
  • the posterior ocular findings observed more frequently were focal pigment mottling and chorioretinal atrophy with a predilection for the macular area and optic disc abnormalities, and congenital glaucoma is rare but can occur. (medscape.com)
  • [2] In addition, up to 45% of astronauts flying missions greater than 30 days demonstrate ocular abnormalities through fundus examination and orbital and brain imaging [7] with or without the presence of subjective symptoms. (aao.org)
  • It can be due to refractive error, binocular fusion abnormalities, or neuromuscular anomalies of ocular movements. (nih.gov)
  • Emerging techniques in biochemistry now permit the examination of the tear film for inflammatory markers and electrolyte concentration: one of the core aims of the unit is to attempt to connect the biological and clinical findings in ocular and systemic abnormalities. (cardiff.ac.uk)
  • These images may occur in the normal eye or may reflect abnormalities of ocular structure. (medscape.com)
  • The project aim is to determine the molecular pathology of a set of three disorders exhibiting a similar congenital ocular phenotype in which the fovea and macular do not develop normally. (fightforsight.org.uk)
  • In most studies, the ZIKV seems related to congenital ocular lesions and most mothers reported mild symptoms during the first pregnancy trimester. (medscape.com)
  • The group also identified the key role of vascular endothelial growth factor (VEGF) in ocular neovascularization, leading to the development of anti-VEGF therapies now administered to millions of children and adults with sight-threatening retinal diseases annually around the world. (massgeneral.org)
  • Pterygium is one of the most common ocular surface diseases. (molvis.org)
  • Discoveries in ocular genomics will extend our understanding of eye diseases/traits by identifying relevant genetic variants, genes and pathways, thereby potentially leading to early detection and effective treatment of many eye disorders which can lead to blindness. (uic.edu)
  • Ocular diseases such as age-related macular degeneration and retinitis pigmentosa are characterized by progressive vision loss due to retinal neuron cell death. (rndsystems.com)
  • Automated detection of ocular diseases with Artificial Intelligence. (edu.au)
  • This range of research has been made possible through my collaborations with engineers, computer scientists, clinicians and health psychologists, and is linked by the aim to impact on the lives of those people living with ocular diseases. (aston.ac.uk)
  • Our basic science researchers are currently engaged in a variety of projects which seek to explain mechanisms of ocular diseases and may lead to possible therapies for blinding disorders. (uthscsa.edu)
  • Information collected included physical and ophthalmic examination findings, results of ocular ultrasound, electroretinogram, magnetic resonance imaging (MRI), and histopathology. (openveterinaryjournal.com)
  • Ophthalmic examination, ocular ultrasound and MRI revealed a complete retinal detachment (RD) in the left eye and vitreous synaeresis in both eyes of both horses. (openveterinaryjournal.com)
  • My research portfolio is broadly based around the role of nutrition in ocular disease, but has included the development and evaluation of ophthalmic instrumentation, clinical trials, the development of hand-held technologies for people with low vision, and investigations of the psychology of nutritional behaviour. (aston.ac.uk)
  • Summary Proper neuro-ophthalmic examination is instrumental in clinical decision-making for the diagnosis and management of concussion, as well as directing future investigations on preventing long-term complications. (researchgate.net)
  • All patients diagnosed with syphilis that exhibit ocular manifestations should immediately be treated for neurosyphilis and be referred for formal ophthalmologic examination. (cdc.gov)
  • Ocular examination revealed a sixth cranial nerve palsy in the left eye. (bvsalud.org)
  • Computed tomography (CT) is the primary imaging examination for the classification of the abscess, etiologic investigation, determining the severity of the process and the relationship with the central nervous system. (bvsalud.org)
  • On ocular examination, perception of light (PL) was present but projection of rays (PR) was absent. (pediatriconcall.com)
  • The Department of Ophthamology and Visual Sciences offers practical experience in examination, investigation and management of patients in the neuro-ophthalmology, retina, cornea, glaucoma, refraction and contact lens, oculo-plastics, genetic and low vision clinics under supervision in addition to general ophthalmology and pediatric ocular motility clinics throughout the week. (ubc.ca)
  • Among them, she is a member of the National Academy of Medicine and a co-recipient of the 2014 António Champalimaud Vision Award, the highest distinction in ophthalmology and visual science. (massgeneral.org)
  • Two warmblood horses, with a common dam and sire, were presented to the ophthalmology department of Liège for investigation of impaired vision. (openveterinaryjournal.com)
  • Two warmblood horses, a 2-year-old, bay colored, Standardbred mare and a 3-year-old, bay colored, Standardbred gelding, were presented to the ophthalmology service of the equine clinic of the University of Liège, Belgium for investigation of decreased vision. (openveterinaryjournal.com)
  • The absence of microcephaly in infants exposed to the zika virus is not indicative of changes in ophthalmology, and it is essential that the ophthalmologist perform the investigations that are relevant to the clinical case. (bvsalud.org)
  • The course of the infection may worsen with extrinsic ocular motility dysfunction, loss of vision and cavernous sinus thrombosis. (bvsalud.org)
  • Pickwell s Binocular Vision Anomalies. (academy.org.uk)
  • Symptoms may be particularly associated with close work and may include frontal headache, ocular fatigue, blurred vision, inertia of accommodation (see notes on Anomalies of Accommodation). (academy.org.uk)
  • Recognition of these lesions by ophthalmologists can help ensure appropriate etiologic evaluation and clinical investigation to define the range of anomalies in an affected infant and determine essential follow-up and ongoing care. (medscape.com)
  • Ocular anomalies have been reported in infants with presumed and laboratory-confirmed prenatal Zika virus (ZIKV) infection. (medscape.com)
  • Describe presenting symptoms associated with ocular adiaspiromycosis. (cdc.gov)
  • Ocular syphilis, an infrequent manifestation of syphilis infection, can cause a variety of eye symptoms, including vision loss. (cdc.gov)
  • Eight jurisdictions that reviewed syphilis surveillance and case investigation data from 2014, 2015, or both found that in 0.6% of syphilis cases, the patient had symptoms consistent with ocular syphilis. (cdc.gov)
  • Ocular syphilis, a manifestation of Treponema pallidum infection, can cause a variety of ocular signs and symptoms, including eye redness, blurry vision, and vision loss. (cdc.gov)
  • Overall, among total syphilis surveillance cases in the jurisdictions evaluated, 0.53% in 2014 and 0.65% in 2015 indicated ocular symptoms. (cdc.gov)
  • Prompt identification of potential ocular syphilis, ophthalmologic evaluation, and appropriate treatment are critical to prevent or manage visual symptoms and sequelae of ocular syphilis. (cdc.gov)
  • A patient whose illness met the surveillance case definition of syphilis ( 3 ) was considered to have a suspected case of ocular syphilis if the patient had concurrent ocular signs or symptoms noted in the surveillance database from a local syphilis case investigation or reported by a local health care provider. (cdc.gov)
  • Children with transient vision loss are less likely to have an ischemic cause for their symptoms and are more likely to have a benign disorder. (medscape.com)
  • I will ask the patient about the onset, duration of the symptoms, associated ocular pain, deacreas in vision? (mrcophth.com)
  • No less important is the fact that more than 60% of wearers will also need a means of vision correction and will not wear AR glasses if they experience symptoms of eye-strain. (medgadget.com)
  • Spaceflight associated Neuro-Ocular Syndrome (SANS)-formerly called visual impairment and intracranial pressure (VIIP) syndrome [1] -is a constellation of findings and symptoms that have been found in astronauts who have undergone long duration space flight (LDSF) missions in microgravity environments (e.g. (aao.org)
  • Her ocular symptoms started on day 11 of DF when she was discharged from the hospital. (thepajo.org)
  • However, the severe symptoms include ocular disease (one would have, like, lesions and bleeding in their eye), and that can lead to vision loss or blindness. (cdc.gov)
  • Tissue-wise, these studies encompass differentiating ocular lens fiber cells, the retina, the brain and the heart. (uclahealth.org)
  • In addition to understanding neural differentiation in the inner retina, so indispensable to retinal function, these studies have a direct bearing on gaining insight into the molecular basis of Emmetropia (In-focus vision) and its dysfunction, Myopia (short sightedness). (uclahealth.org)
  • In astigmatism, the curvature of the cornea is irregular, causing light rays to focus in more than one place so that a single clear image cannot be formed on the retina, resulting in blurred vision. (emeraldparkeyecare.com)
  • Cones are principally found in the central retina and provide a detailed vision for such tasks as reading or distinguishing distant objects. (emeraldparkeyecare.com)
  • therefore, the optic nerve must cross through the retina en route to the brain. (wikipedia.org)
  • [9] Some vertebrates, including humans, have an area of the central retina adapted for high-acuity vision. (wikipedia.org)
  • The ocular tissue where these tumors arise, the uvea, is a densely pigmented layer that lies for the most part between the sclera and the retina. (medscape.com)
  • Ocular exposure might result in blurred vision, and inhalational exposure might cause nasal irritation and cough. (cdc.gov)
  • Most of the patients (86.7%, n=13) presented with blurring of vision, with 3 of them reporting concomitant floaters (Table 1). (annals.edu.sg)
  • One patient reported having floaters without blurring of vision. (annals.edu.sg)
  • There was no history of floaters, photopsia, and pain on ocular movements. (thepajo.org)
  • An R&D Blueprint roadmap is a framework document laying down a vision, strategic product development and research goals and priority areas for accelerated R&D to prevent and control severe emerging pathogens with epidemic potential. (who.int)
  • [1] The most common ocular symptom reported by patients having dengue fever (DF) is blurring of vision. (thepajo.org)
  • This case report warrants the importance of ocular screening in a patient having systemic complications of DF. (thepajo.org)
  • Describe the frequency of ocular lesions associated with adiaspiromycosis. (cdc.gov)
  • The aim of this study was to review the ocular findings related to the Zika virus (ZIKV) based on the main studies published to date, describe the patterns of the lesions and risk factors, and identify the public health implications and scientific importance of this emerging disease. (medscape.com)
  • Although the full spectrum of ocular lesions caused by the ZIKV infection is not yet determined, a distinctive new disease has been observed. (medscape.com)
  • As well as Ocular Electrophysiology the department specialises in ocular ultrasound including ultrabiomicroscopy (UBM) and high frequency posterior segment ultrasound. (swbh.nhs.uk)
  • The Department also provides other imaging investigations included anterior and posterior segment OCT and corneal topography. (swbh.nhs.uk)
  • Transient vision loss may be related to local ocular conditions, such as ocular surface disorders (eg, dry eyes), intraocular foreign bodies or masses, central or branch retinal vein occlusion, central or branch retinal artery occlusion, arteritic anterior ischemic optic neuropathy, intermittent angle closure glaucoma, hyphema, and optic neuritis. (medscape.com)
  • This may open new avenues of investigation into human ocular traits and their relationship to the risk of vision disorders. (kaiserpermanente.org)
  • Due to the genetic heterogeneity, the fundal features are highly variable as well but patients usually have symmetrical ocular findings. (gene.vision)
  • The ACVO Vision for Animals Foundation funds research grants that further medical findings for animals (and humans). (visionforanimals.org)
  • Current investigations include the Mexican American Glaucoma Genetic Study (MAGGS), which aims at identifying genetic determinants related to open angle glaucoma in Mexican Americans, and investigations into the genetics of diabetic retinopathy and age-related macular degeneration in admixed and minority populations. (uic.edu)
  • Absolute glaucoma is defined as total loss of both peripheral and central vision and may be associated with reduced light perception. (pharmacology2000.com)
  • Studies in English conducted before February 2023 that reported the level of, and/or barriers to, non-adherence or non-persistence to intravitreal anti-VEGF ocular disease therapy were included. (bvsalud.org)
  • Education of both patients and providers is critical to identify ocular manifestations of syphilis and manage disease sequelae. (cdc.gov)
  • Over the last two decades, she and her colleagues at Mass Eye and Ear/Harvard Medical School pioneered the development of photodynamic therapy using verteporfin (Visudyne®), the first approved pharmacological therapy able to reduce and slow vision loss in patients with AMD. (massgeneral.org)
  • Some patients have had ocular examinations during the transient vision loss event that demonstrate the visible vasospasm on clinical exam, fundus photography, or fluorescein angiography. (medscape.com)
  • The system will be tailored to the needs of vision impaired patients who will benefit from both lens-based vision correction and from magnification and digital enhancement of the view of their surroundings. (medgadget.com)
  • The eMacula solution responds directly to the fact that the vision of these patients cannot be sufficiently improved by techniques based on the use of normal glasses lenses or contact lenses. (medgadget.com)
  • Presenting visual acuity (VA) ranged from 6/7.5 to perception of light with 7 patients (46.7%) having vision of hand movement only or worse. (annals.edu.sg)
  • Of these, 4 patients (26.7%) had culture-proven sources of extra-ocular infection (Patients 3, 6, 9 and 13). (annals.edu.sg)
  • We are committed to serve our patients and our community, to prepare physicians to care for their patients, and to the development and propagation of new concepts to preserve and enhance vision. (uthscsa.edu)
  • Causes of ischemic transient vision loss include giant cell arteritis, cerebrovascular ischemia, and retinal arteriolar emboli. (medscape.com)
  • The existence of mammalian retinal stem cells in vivo remains an active area of investigation. (rndsystems.com)
  • Endophthalmitis refers to the inflammation of the ocular cavities and their immediate adjacent structures without extension beyond the sclera, usually secondary to infection. (annals.edu.sg)
  • Erythema and conjunctivitis: investigation of an outbreak in a school gymnasium caused by unintentional exposure to ultraviolet radiation from metal halide lamps. (cdc.gov)
  • Postprandial visual loss is most common in individuals whose ocular perfusion is already compromised (eg, carotid disease). (medscape.com)
  • These studies entail attempts at relating gene activity to the functional phenotype of vision. (uclahealth.org)
  • We conducted an epidemiologic investigation of an outbreak of ocular disease among children to determine whether the disease was linked to Emmonsia sp. (cdc.gov)
  • Two interrelated paradigms currently under investigation are: 1) Molecular basis of the differential expression of the gene for the small heat shock protein Alpha B-crystallin, a protein associated with with vision (e.g. in the ocular lens), oncogenesis (e.g. in breast cancer) and neural degeneration (e.g. in Alzheimer's disease). (uclahealth.org)
  • Some authors refer to ischemic transient vision loss as amaurosis fugax syndrome, so transient vision loss can be a symptom of a serious vision or life-threatening condition, requiring urgent investigation and treatment, or it may have a more benign origin (eg, migraine, dry eye). (medscape.com)
  • Although syphilis is nationally notifiable, ocular manifestations are not reportable to CDC. (cdc.gov)
  • After this advisory, eight jurisdictions performed a review of syphilis surveillance and case investigation data to identify syphilis cases with ocular manifestations. (cdc.gov)
  • One (6.7%) patient (Patient 10) had septicaemia without any localising foci of infection despite extensive investigations. (annals.edu.sg)
  • The patient underwent complete clinical, neurological, and neuroimaging investigations, including cerebrospinal fluid sample analysis to rule out infectious causes. (bvsalud.org)
  • http://www.ncbi.nlm.nih.gov/pubmed/1841573?tool=bestpractice.com When in isolation, primary demyelinating ON is considered a forme fruste of MS. ON manifests as the subacute or acute onset of pain in the eye and pain with eye movements and loss of vision, typically with central or centrocecal scotoma that usually reaches a nadir at approximately 1 to 2 weeks. (bmj.com)
  • Objective To assess the performance of a deep learning system (DLS) to discriminate between optic disc drusen (ODD) and papilledema caused by intracranial hypertension, using standard color ocular fundus photographs collected in a large international multi-ethnic population. (medrxiv.org)
  • In adults, transient vision loss (TVL) is a frequently encountered complaint that, in most cases, has an identifiable cause. (medscape.com)
  • [ 1 ] Transient vision loss may be unilateral or bilateral and may last from seconds to hours. (medscape.com)
  • Transient vision loss in children is less common than in adults and is more likely to have a benign origin. (medscape.com)
  • Transient vision loss is a symptom rather than a diagnosis. (medscape.com)
  • Embolic occlusions of the arteries supplying the eye are a common cause of transient vision loss in adults. (medscape.com)
  • Arteritic anterior ischemic optic neuropathy (AAION) also may present with transient vision loss, but in general, transient vision loss does not occur prior to nonarteritic AAION. (medscape.com)
  • Vasospasm may cause a temporary reduction in blood flow to the visual system and transient vision loss. (medscape.com)
  • Causes of bilateral vision loss in children include migraine and, less commonly, epileptic seizure. (medscape.com)
  • Gaze-evoked amaurosis (compression) is transient vision loss occurring when looking in a particular direction. (medscape.com)
  • The National Ethical and Research Com- optic neuropathy, that result in vision loss mittee of Oman approved this community- and blindness. (who.int)
  • A 17-year-old female presented with sudden painless loss of vision in her both eyes for 2 days associated with redness of eyes. (thepajo.org)
  • The patient did not have any ocular complaints, and her vision was satisfactory before the development of loss of vision in her eyes. (thepajo.org)
  • moreover, central vision acuity is not affected even in cases of substantial overall visual field loss. (pharmacology2000.com)
  • Transient visual loss can therefore be a symptom of a serious vision or life-threatening condition, requiring urgent investigation and treatment, or it may have a more benign origin (eg, migraine). (medscape.com)
  • See The Case of the Middle-Aged Woman with Sudden Unilateral Vision Loss , a Critical Images slideshow, to help identify and treat malignant intraocular tumors. (medscape.com)
  • Microphthalmia may or may not result in significant vision loss. (medlineplus.gov)
  • In early 2015, clusters of ocular syphilis cases were reported in Washington and California. (cdc.gov)
  • Medical, UK) was focused on the embolus, using a Mainster Standard fundus contact lens (Ocular, California, USA). (who.int)
  • The aim of this systematic review was to demonstrate the need for further investigation into the prevalence of, and factors contributing to, patient-led non-adherence and non-persistence, thus facilitating improved clinical outcomes. (bvsalud.org)
  • The personalized contact lens component of the eMacula system incorporates the wearer's usual vision prescription, but also a small lens at its center which enables the user to focus on digital content provided by near-eye microdisplays mounted within the glasses. (medgadget.com)
  • Innovega has also designed an intra-ocular lens that could be surgically implanted during cataract surgery inside the eye, which can provide the user with an improved view of their surrounding, plus an ability to view near-eye, high performance displays mounted in smart glasses. (medgadget.com)
  • This new generation of "smart" contact lens incorporates the wearer's vision prescription (if required) to ensure a clear, real-world view as well as a lens that delivers in-focus clarity of over-laid media. (medgadget.com)
  • The Contact Lens and Anterior Eye Research Unit (CLAER) was established within the Clinical Investigation and Vision Sciences Research Group in September 2001, and continues to expand. (cardiff.ac.uk)
  • The ocular antiaggregation therapy, transluminal laser motilities were unlimited and there was no embolysis and selective intra-arterial lysis significant pathology in the anterior seg- of the clot [ 3 ]. (who.int)
  • A standard form was used to abstract de-identified information on each case, including demographic information, syphilis stage and treatment, and any information on extent of ocular involvement. (cdc.gov)
  • Studies have shown that the involvement of ocular structures indicates the correction of thrombocytopenia. (thepajo.org)
  • Since the introduction of this technology, there have been few investigations comprehensively reporting outcomes, particularly for hyperopic treatments. (uwaterloo.ca)
  • Her ocular history was most physicians tend to use a combina- unremarkable, except for a dacryocystorhi- tion of treatments with low potential side- nostomy procedure performed 5 months effects. (who.int)
  • Transient hypoxia of any part of the visual system can result in a temporary disturbance of vision. (medscape.com)
  • There was no history of trauma or previous ocular problems reported but poor vision was suspected due to their abnormal behavior. (openveterinaryjournal.com)
  • Identify the age group most susceptible to ocular adiaspiromycosis. (cdc.gov)
  • Identify risk factors for ocular adiaspiromycosis. (cdc.gov)
  • The medical practitioner needs to be able to identify when an ocular pathology requires intervention immediately or within 24 hours, or can be referred to outpatients. (500mgmetronidazole-flagyl.com)
  • Clusters of ocular syphilis were reported from late 2014 to 2015. (cdc.gov)
  • In the United States, syphilis rates have increased since 2000, but little is known about ocular syphilis cases. (cdc.gov)
  • After ocular syphilis clusters were reported in early 2015, CDC issued a clinical advisory ( 1 ) in April 2015 and published a description of the cases in October 2015 ( 2 ). (cdc.gov)
  • A total of 388 suspected ocular syphilis cases were identified, 157 in 2014 and 231 in 2015. (cdc.gov)
  • Five jurisdictions described an increase in suspected ocular syphilis cases in 2014 and 2015. (cdc.gov)
  • CDC issued a clinical advisory, notifying clinical providers and health departments of a potential increase in suspected ocular syphilis cases. (cdc.gov)
  • Cones function in well-lit conditions and are responsible for the perception of colour through the use of a range of opsins , as well as high-acuity vision used for tasks such as reading. (wikipedia.org)
  • Investigation into the Genetics of Snow Leopard (Panthera uncia) Multiple Ocular Coloboma, Dr. Tim Georoff, Philadelphia Zoo ($29,150). (visionforanimals.org)
  • Ocular Health study" - Actually, seeing that astronauts often experience "flashes" from the interaction of hard cosmic radiation with the material in their eyeballs, I would have expected both eyesight and the immune system (q.v. the other study mentioned) to be affected more by radiation than gravity. (nasa.gov)
  • Conclusions: This project has established a data repository that provides an analytic foundation for the study of DFE follow-up as well as the basis for future investigations of other aspects of patient care. (confex.com)