• In their efforts to find teachers for hard-to-staff schools by creating multiple pathways into teaching, districts from New York City to Los Angeles are in the midst of what amounts to a national experiment in how best to recruit, prepare, and retain teachers. (stanford.edu)
  • It can be concluded that the QZF in treatment of SS is the result of the combined action of multiple components, multiple targets, and multiple pathways. (hindawi.com)
  • Explore the multiple pathways you can take in medicine throughout your professional journey. (ama.com.au)
  • It mainly acts on biological processes such as inflammatory response, chemokine metabolic process, and immune response as well as pathways such as FoxO signaling pathway, Yersinia infection, HIF-1 signaling pathway, and TNF signaling pathway. (hindawi.com)
  • At Harvard University the chemical biologist looks for new metabolic pathways to investigate how gut bacteria interact with one another and their hosts. (the-scientist.com)
  • In this study, we altered these metabolic pathways pharmacologically in order to further delineate the role of specific antioxidants in the protection of the cochlea. (cdc.gov)
  • The aim of this study was to investigate if the metabolic regulators sirtuins are affected in HD. (lu.se)
  • We show that SIRT1 expression is increased in HD-affected brain regions and that metabolic pathways are altered in the HD hypothalamus. (lu.se)
  • ATSDR could not evaluate this pathway because it has not yet been investigated. (cdc.gov)
  • But Agency for Toxic Substances and Disease Registry (ATSDR) scientists can investigate whether the amounts of exposure in a particular area can harm the people who live or work there. (cdc.gov)
  • Stay tuned for future blog posts that describe exposure pathways investigated by ATSDR scientists. (cdc.gov)
  • He also investigated numerous pathways in the pathogenesis of retinal disease. (aao.org)
  • To investigate the mechanisms of CuO-induced pathogenesis, the effect of CuO on AP-1-MAPKs and ROS generation were investigated. (cdc.gov)
  • This prevents a full understanding of causal pathways towards the shared risk of these diseases and the development of coordinated preventive and therapeutic interventions. (plos.org)
  • The project takes advantage of human longitudinal birth cohort data, animal studies and cellular models to test the hypothesis of shared mechanisms and molecular pathways by which ELS shapes an individual's physical and mental health in adulthood. (plos.org)
  • Given the potential for advances in molecular profiling to help overcome methodological challenges in nutrition research and delineate the underlying biological pathways, emphasis is placed on conducting molecular epidemiological research that integrates metabolomics, hormone measurements, the microbiome, and genomics, within population-based cohorts and intervention studies. (who.int)
  • We seek to investigate the molecular mechanisms and pathways underlying neuroblastoma treatment relapse. (lu.se)
  • Vapor intrusion may be an exposure pathway for TCE. (cdc.gov)
  • Ever heard of an exposure pathway? (cdc.gov)
  • An exposure pathway is the route a substance takes from its source (where it began) to its end point (where it ends), and the ways people can come into contact with it (or be exposed to it). (cdc.gov)
  • We will investigate bacterial communication mechanisms involved in pathogen fitness and formation of complex communities in plants to identify factors critical for disease. (usda.gov)
  • The mechanisms underlying this effect have not been investigated. (lu.se)
  • Our overall goals are to investigate mechanisms of treatment resistance and to identify and test novel therapies against high-risk neuroblastoma. (lu.se)
  • After identifying these pathways, researchers conducted behavioral tests on the mice to assess fear and memory. (medicalnewstoday.com)
  • Accordingly, using the above proposed schemes, the researchers investigated the performance of all-optical exclusive-OR (XOR) logic gates at high operating temperatures. (phys.org)
  • Researchers from the Center for Cognition and Sociality within the Institute for Basic Science (IBS) identified the brain pathway where ABS works to induce a persistent fear reduction. (sciencedaily.com)
  • Using these experiments, the researchers identified the SC-MD pathway is essential for preventing the return of fear. (sciencedaily.com)
  • Using a yellow laser light, the researchers blocked the MD-BLA pathway. (sciencedaily.com)
  • Researchers investigate proteins to uncover new biological pathways and hunt for disease cures. (the-scientist.com)
  • A recent study from the Salk Institute for Biological Studies in La Jolla, California, may have uncovered one of those pathways. (medicalnewstoday.com)
  • However, a systems biological analysis of the lipidome, by incorporating pathway information remains challenging, leaving lipidomics behind compared to other omics disciplines. (mdpi.com)
  • and (iii) investigating multimorbidity and biological pathways common to cancer, diabetes, and cardiovascular disease. (who.int)
  • Tough H, Gross Hemmi M, Eriks Hoogland I, Fekete C. Pathways to loneliness: a mediation analysis investigating the social gradient of loneliness in persons with disabilities in Switzerland. (swisci.ch)
  • Genetic causes, like mutation or polymorphism of the genes specifically involved in this neuronal pathway, may intrinsically alter the signal transmission of this pathway," Dr. Han said. (medicalnewstoday.com)
  • Conversely, when blue laser light stimulated the neuronal activities in the SC-MD pathway, mice showed significantly reduced freezing without fear relapses. (sciencedaily.com)
  • Using differently colored fluorescent proteins, they were then able to track the pathways of signals leaving the thalamus - a brain region responsible for relaying sensory information - and brainstem. (medicalnewstoday.com)
  • Bioinformatic analysis of the proteomic phenotypes revealed shared Gene Ontology (GO) terms and signaling pathways within the clusters of co-expressed proteins (see Tables 1-2 ). (lu.se)
  • Signalling pathways and identified proteins involved. (lu.se)
  • In Kentucky's Teaching and Learning career pathway you can explore teaching and acquire skills that will be helpful as an educator and in other professions while earning credit toward your college degree. (eku.edu)
  • This report augments guidelines published in 1990 for investigating clusters of health events (CDC. (cdc.gov)
  • Guidelines for investigating clusters of health events. (cdc.gov)
  • In 1990, CDC published guidelines for investigating clusters of health events (the 1990 Guidelines) ( 1 ). (cdc.gov)
  • Many state, local, and tribal health departments have used the 1990 Guidelines as a basis for developing and implementing protocols to investigate suspected cancer clusters, employing the four-step approach (initial response, assessment, major feasibility study, and etiologic investigation) identified in the 1990 Guidelines. (cdc.gov)
  • Recognizing the potential for new pathways of transmission, the authors investigated other possible exposures to Nipah virus by applying epidemiologic and anthropological approaches in the study of these 3 Nipah virus disease clusters. (cdc.gov)
  • We postulate that specific immune response associated signalling, affecting gene transcription networks, may be associated with the activation of different oncogenic pathways in aggressive Non-Hodgkin lymphomas (NHL). (nih.gov)
  • We defined the extent to which different immune response associated pathways are responsible for differences in gene expression which distinguish individual DLBCL cases. (nih.gov)
  • When analyzing the data, the scientists discovered that two separate groups of CGRP neurons in the brainstem and the thalamus relay signals to the nonoverlapping area of the amygdala - forming two pathways. (medicalnewstoday.com)
  • The scientists also found that both pathways are involved in forming unpleasant memories, which may help an individual avoid the same threat in the future. (medicalnewstoday.com)
  • To determine toxic exposure, scientists must find the complete pathway a substance takes from its source to get into a human body. (cdc.gov)
  • A research consortium led by Ford Research and Innovation Center Aachen is currently investigating the technical conditions under which diesel vehicles can run on dimethyl ether (DME) as an alternative fuel. (greencarcongress.com)
  • A public-private partnership between Los Alamos National Laboratory and Southern California-based Oberon Fuels has secured funding from the US Department of Energy (DOE) to scale-up steam reforming technology to produce renewable hydrogen (rH2) from renewable dimethyl ether (rDME)-a novel pathway for reducing the carbon content of the global hydrogen supply. (greencarcongress.com)
  • Members of the marine Roseobacter clade can degrade dimethylsulfoniopropionate (DMSP) via competing pathways releasing either methanethiol (MeSH) or dimethyl sulfide (DMS). (beilstein-journals.org)
  • While these systems may harbor substantial levels of biodiversity, they remain inadequately investigated. (usgs.gov)
  • The study aims to investigate whether an inflammatory molecule called suPAR is elevated in diabetic kidney disease, and whether it can be used as a marker for early detection of atherosclerosis or cardiovascular disease in type II diabetic patients. (hmri.org.au)
  • This "in vivo biochemistry" approach has enabled us to demonstrate that there are in fact several independent, competing pathways of homologous recombination, each with its own genetic requirements. (brandeis.edu)
  • We here demonstrate for the first time that GDNF enhances GABAergic inhibitory drive onto mouse pyramidal neurons by modulating postsynaptic GABAA receptors, particularly in perisomatic inhibitory synapses, by GFRα1 mediated activation of the Ret receptor pathway. (lu.se)
  • We extend the Mendelian randomization paradigm to investigate more complex networks of relationships between variables, in particular where some of the effect of an exposure on the outcome may operate through an intermediate variable (a mediator). (nih.gov)
  • While the general sequence of SNARE complex formation is well-established, our knowledge on possible intermediates and stable off-pathway complexes is incomplete. (nature.com)
  • In summary, we unravel the stoichiometry of intermediates and off-pathway complexes and compile a road map of SNARE complex assembly including regulation by Complexin-1. (nature.com)
  • In this article, we will discuss what schizophrenia is and what its potential causes are, and then introduce some of our recent research to investigate the combined genetic and environmental influences that can lead to this devastating condition. (scienceinschool.org)
  • To investigate the genetic basis of the underlying regulatory pathways related to objective (i). (uu.nl)
  • While a certain amount of fear and anxiety are normal, an over-exposure to fearful or stressful events has the potential to result in causing the fear pathways to become "hyperactive. (medicalnewstoday.com)
  • The experimental model can now be applied to study the therapeutic potential of deregulated oncogenic pathways and to develop individual treatment strategies for lymphoma patients. (nih.gov)
  • It is clear to the former co-facilitators that Member States consider that any agreed process for handling and investigating potential allegations against WHO Directors-General should be squarely in their hands. (who.int)
  • DRYDEN - On March 2, 2020, at approximately 9:53 pm, members of the Dryden Detachment of the Ontario Provincial Police (OPP) were called to investigate a serious incident at the Arbour Jade trailer park located on McGogy Road in Dryden, Ontario. (netnewsledger.com)
  • In addition, Ingenuity Pathway Analysis (IPA) integrated with PCR array data showed that the JAK1/STAT3 pathway was significantly altered by cells overexpressing DEFB1 , suggesting that this may be one of the pathways by which defensin regulates IAV replication in HBEpCs. (cdc.gov)
  • The role of DMSP degradation pathways for MeSH and DMS formation was further investigated by using the synthetic analogue DMTeP as a probe in feeding experiments with the wild-type strain and knockout mutants. (beilstein-journals.org)
  • Investigating the role of vertebrate evolution in shaping the history of life on Earth. (nhm.ac.uk)
  • 3.A: Investigate the role of antimicrobials in tolerance to bacterial soft rot pathogens. (usda.gov)
  • This week examines the role of business models and role of financing is investigated and illustrated through examples and experiences with nature-based solutions. (lu.se)
  • This week discusses the role of visions and pathways is discussed with examples of nature-based solutions and different ways of working with nature, cities and innovation. (lu.se)
  • This article provides an overview of a research project that examines features of these different pathways into teaching in New York City schools and the impact of these features on where teachers teach, how long they remain in the classroom, and student achievement in reading and math as measured by value-added analyses. (stanford.edu)
  • Yet the brain pathways responsible for gathering threatening information from the body's sensory system and initiating the fear response are not fully understood, but new research offers some clues. (medicalnewstoday.com)
  • Using a community school in Marondera, Zimbabwe, as an example, this research explored four pathways: grid extension, solar with storage, wind energy, and biomass energy to provide electricity. (ed.ac.uk)
  • What will you investigate in your research? (lu.se)
  • Alternatively, acquired traumatic experiences may also alter the plasticity of this pathway. (medicalnewstoday.com)
  • Sub-objective 1.B: Investigate diversity of soft rot Pectobacteriaceae (SRP). (usda.gov)
  • Sub-objective 2.E: Characterize the signaling pathways that impact expression of HiVir gene cluster in Pantoea. (usda.gov)
  • Objective 3: Investigate sustainable strategies for control of bacterial plant diseases. (usda.gov)
  • The NHS will talk to family members of people who have died on the pathway, investigate complaints and speak with clinicians. (lifeissues.net)
  • Study authors suggest that identifying these pathways may offer insights into treating fear-based mental health conditions. (medicalnewstoday.com)
  • MNT also spoke with Sung Han , PhD, senior author of the study and assistant professor at the Salk Institute, about factors that may cause these pathways to become overactive in some people but not others. (medicalnewstoday.com)
  • Investigating oral and systemic pathways between unhealthy and healthy dietary patterns to periodontitis in adolescents: A population-based study. (bvsalud.org)
  • The study aims to contribute to academic debates on alternative agricultural food pathways that address social, economic, and environmental sustainability challenges engendered in the conventional industrial model. (lu.se)
  • Does your high school have a Career and Technical Education Teaching and Learning Career Pathway? (eku.edu)
  • Exploring your job options investigating a new career? (google.com)
  • The expression of top 100 genes which had a change in gene expression following stimulation was investigated in gene expression profiles of patients with Aggressive non-Hodgkin Lymphoma (NHL). (nih.gov)
  • Our results support the view that tonic or constitutively active MAPK/ERK pathways are an important part of oncogenic signalling in NHL. (nih.gov)
  • Aggressive Non-Hodgkin lymphomas (NHL) are a group of lymphomas derived from germinal centre B cells which display a heterogeneous pattern of oncogenic pathway activation. (nih.gov)
  • We provide an in vitro model system to investigate pathway activation in lymphomas. (nih.gov)
  • The signal transduction pathways for AP-1 activation were also investigated. (cdc.gov)
  • Both homologous recombination, in which the ends of the broken DNA seek out intact templates with the same sequence, and nonhomologous end-joining pathways are found in Saccharomyces as they are in humans. (brandeis.edu)
  • Pathways to Ancient Britain (PAB) focuses on three chronological periods of human presence in the British Isles, from the earliest occupation through to extinction of the Neanderthals and the emergence of modern humans. (nhm.ac.uk)
  • This article outlines the CLIL educational pathway that has been developed by a teacher community in Jyväskylä in recent years. (jyu.fi)
  • Pressure from the British media has forced an investigation into the controversial Liverpool Care Pathway by National Health Service and the Association of Palliative Medicine. (lifeissues.net)
  • Learn about a variety of pathways from the people who do those jobs. (google.com)
  • During the next two weeks, the blog will feature a series of six posts explaining exposure pathways or the ways in which people can come into contact with toxic substances. (cdc.gov)
  • We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. (lu.se)
  • It is self-evident that stopping fluids whilst giving narcotics and sedatives hastens death… The median time to death on the Liverpool Care Pathway is now 29 hours. (lifeissues.net)
  • The Liverpool Care Pathway has sometimes been accused of being a way of withholding treatment, including hydration and nutrition. (lifeissues.net)
  • 11 Investigate Aboriginal and Torres Strait Islander employment pathways. (fedcourt.gov.au)
  • After detecting the trajectories, the effects of independent variables (individual employment, education, physical activity, and paternal smoking, employment and education) on the trajectories were investigated. (who.int)
  • Knockout of relevant genes from the known DMSP demethylation pathway to MeSH showed in both species a residual production of [ 2 H 3 ]MeSH, suggesting that a second demethylation pathway is active. (beilstein-journals.org)
  • When well over 100,000 are dying on the LCP each year, the suspicion inevitably arises that the pathway is being used to hasten death and free up beds," said the Daily Mail in an editorial . (lifeissues.net)
  • To investigate pathways between unhealthy and healthy dietary patterns and periodontitis in adolescents (18-19 years of age). (bvsalud.org)
  • They wondered if this SC-MD pathway might be the route where ABS travels, thereby resulting in the reduction of fear. (sciencedaily.com)
  • We investigated the effects of sodium thiosulfate (STS), a CN inhibitor, 4-methylpyrazole (4MP), a drug that blocks CN generation by competing with CYP2E1, and l-N-acetylcysteine (l-NAC), a pro-GSH drug, in order to distinguish between GSH depletion and CN production as the mechanism responsible for potentiation of NIHL by ACN. (cdc.gov)