• This, in turn would increase the levels of osteocalcin which is responsible for bone formation. (umc.edu)
  • The osteogenic differentiation of PDLSCs were assessed by ALP staining and Alizarin Red staining as well as the mRNA and protein levels of osteogenic marker genes osterix, osteocalcin, and alkaline phosphatase through qRT-PCR and western blot. (biomedcentral.com)
  • Therefore, this study aims to investigate the remission effect of canagliflozin and metformin on participants with newly diagnosed T2DM and its possible underlying mechanism(s) through which these two medications elicit diabetes remission. (bvsalud.org)
  • Objective:To investigate the application effect of paper review combined with situational exercise in the standardized training and teaching of ophthalmology nurses.Methods:A total of 39 ophthalmology nurses who received standardized training from September 2019 to July 2020 were selected as control group, and 42 ophthalmology nurses who received standardized training from September 2020 to July 2021 were selected as study group. (bvsalud.org)
  • needed to investigate the effect of CH on Nrf2- AREsignaling. (researchgate.net)
  • In brief, lncRNA plays an important role in osteogenic differentiation of PDLSCs and our study will further investigate the effects of lncRNA SNHG1 in osteogenic differentiation of PDLSCs and explore the underlying mechanism. (biomedcentral.com)
  • The purpose of the current study was to investigate whether lncRNA SNHG1 was mechanistically involved in the osteogenic differentiation of PDLSCs. (biomedcentral.com)
  • Objective: To investigate current use of oral anticoagulant (OAC) therapy and influencing factors among coronary artery disease (CAD) patients with nonvalvular atrial fibrillation (NVAF) in China. (bvsalud.org)
  • In a nine-year, population-based study of 236 women, progression of atherosclerotic calcification was associated with increasing bone loss. (medscape.com)
  • [ 7 ] These women also had a 0.32-ng/mL higher adjusted undercarboxylated osteocalcin level (95% CI, 0.03-0.61 ng/mL) and lower hydroxyapetite-binding capacity than those women without aortic calcification. (medscape.com)
  • It is generally thought that calcifications are composed of hydroxyapatite in advanced atherosclerotic lesions and that atherosclerotic calcification occurs passively as the result of precipitation of calcified material in cores of dying cells. (tue.nl)
  • However, recent findings might indicate that atherosclerotic calcification is an actively regulated process involving, among others, bone matrix regulatory proteins. (tue.nl)
  • Data about the distribution and composition of the calcifications at a very early stage of the atherosclerotic process are scarce, as is information whether trace-elements could be involved in the calcification process. (tue.nl)
  • Chemical bulk analysis of the mineral part of human aortas, with advanced atherosclerotic lesions, showed that the average mass ratio of calcium to phosphorus is close to the ratio of hydroxyapatite, i.e. 2.16, which is the main constituent of bone tissue1. (tue.nl)
  • [ 6 ] However, only a few human studies investigating the connection between these two diseases have been published. (medscape.com)
  • In a pioneering study of by Pallon et al.4 the co-localization of iron and zinc with calcium granules, 10 to 20 µm in diameter, was observed in early atherosclerotic lesions in human coronary arteries. (tue.nl)
  • AB - A panel of monoclonal antibodies to monomorphic determinants of the MHC class II subregion locus products: DP, DR and DQ, was used to investigate the expression of these antigens on early lymphocytes and macrophages from human fetal liver (13 20 weeks), placenta (16 weeks and term) and cord blood, in relation to the class II phenotype of cells from adult tonsil and peripheral blood. (nih.gov)
  • To investigate the distribution, composition (calcium-to-phosphorus mass ratio) and trace-element contents of calcifications in early atherosclerotic lesions a technique was applied with high sensitivity, specificity and resolution, i.e., micro-Proton Induced X-ray Emission in combination with Backscattering and Forward Scattering Spectroscopy5, 6. (tue.nl)
  • Only a few studies have investigated the influence of physical function and activity on collapse in patients with osteoporotic vertebral fractures. (asianspinejournal.org)