Invasive pneumococcal infection streptococcus pneumoniae. Medical search. Frequent questions

The impact PCV15 and PCV20 will have on drug-resistant pneumococcal serotypes is yet to be determined. (cdc.gov)
In particular, the recommendations provide guidance on the design of immunogenicity studies that should be performed in order to support the licensure of new pneumococcal conjugate vaccines (including those containing conjugated capsular polysaccharides of serotypes additional to or different from those in already licensed vaccines). (who.int)
The authors did this by analyzing information from case reports over time and by doing tests on the particular pneumococci causing these infections to see what serotypes they were. (cdc.gov)
At least 100 pneumococcal serotypes were documented as of 2020 ( 5 - 7 ). (cdc.gov)
During 2018-2019, approximately 60%-75% of all IPD in adults was caused by the 24 pneumococcal serotypes that were included in the formulations of commercially available polysaccharide conjugate vaccine (PCV) or pneumococcal polysaccharide vaccine (PPSV) vaccines (i.e. (cdc.gov)
VAXNEUVANCE is indicated in the U.S. for active immunization of adults 18 years of age and older for the prevention of invasive disease caused by the S. pneumoniae serotypes contained in the vaccine. (merck.com)
New data from Phase 3 European clinical trials reinforce that Wyeth's (NYSE: WYE) investigational pneumococcal vaccine, Prevenar 13* (Pneumococcal Polysaccharide Conjugate Vaccine, 13-valent [Adsorbed]), has the potential to provide coverage against the 13 most prevalent serotypes associated with pneumococcal disease (PD), the leading cause of vaccine-preventable death in children younger than five worldwide. (science20.com)
The serotypes of 225 S. pneumoniae strains isolated between 1997 and 2011 were identified with the Quellung reaction and serotype-specific PCR. (biomedcentral.com)
This study identified the serotypes/subtypes and CCs/STs of group 6 S. pneumoniae present in China. (biomedcentral.com)
So far, more than 90 pneumococcal serotypes, classified into 46 groups, have been identified. (biomedcentral.com)
We set out to identify any new serotypes (serotypes "6E", "6F", and "6G") in serogroup 6 S. pneumoniae in China and to report the population biology of this group. (biomedcentral.com)
To this end, they are including most common serotypes for preventing invasive pneumococcal diseases in paediatrics. (medgadget.com)
The six serotypes included in the new 13-valent pneumococcal conjugate vaccine, but not in the 7vPCV, accounted for 40.6% of IPD cases in the zero to four year age group during the period of 2008-2010. (who.int)
Some serotypes are carried in the upper respiratory tract and others are more associated with the invasive disease. (who.int)
Prior to the introduction of pneumococcal vaccines into the Australian immunization schedule, 83%-85% of IPD cases in children aged less than 14 years and 69% of IPD cases in adults aged more than 65 years in the state of New South Wales (NSW) could be attributed to the seven serotypes found in the 7-valent pneumococcal conjugate vaccine (7vPCV) ( Box 1 ). (who.int)
Introduction We performed a study to describe the clinical profile, antimicrobial susceptibility and prevalent serotypes of pneumococcal isolates from children with suspected invasive pneumococcal disease (IPD) admitted to a tertiary care hospital in South India. (johnshopkins.edu)
Invasive pneumococcal infection in children and adults: incidence, serotypes and genotypes. (biodonostia.org)
Each component of current protein-polysaccharide conjugate vaccines (PCVs) generally induces immunity specific to one of the approximately 100 pneumococcal serotypes, and typically eliminates it from carriage and IPD through herd immunity. (uit.no)
Although the pneumococcal conjugate vaccine (PCV) has led to reductions in IPD incidence, cases of IPD caused by serotypes not included in PCV are increasing. (elsevierpure.com)
Following the introduction of pediatric 13-valent pneumococcal conjugate vaccine (PCV13) programs, SPN3 declines are less than other vaccine serotypes and incidence has increased in some populations coincident with a shift in predominant circulating SPN3 clade, from I to II. (ox.ac.uk)
serotypes were 19F, 14, 23F, 6B and 19A and the theoretical coverage of the 7, 10 and 13-valent pneumococcal conjugate vaccines was 60%, 78% and 91% respectively. (who.int)
Before the 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the United States in 2000, the seven pneumococcal serotypes covered by the vaccine (4, 6B, 9V, 14, 18C, 19F, and 23F) caused 80% of invasive pneumococcal disease (IPD) cases among young children, and the incidence of IPD was relatively stable. (unboundmedicine.com)
OBJECTIVES: The objective of this study is to see the clinical profile of invasive pneumococcal disease, antibiotics sensitivity pattern and prevalent serotypes in children admitted at Patan Hospital. (ox.ac.uk)
The serotypes in this vaccine are 4, 23F, 6B, 19F, 18C, 14 and 9V, which have an average coverage of 62% for pneumococcal invasive disease in Colombia. (univalle.edu.co)
For Germany, we have described earlier the distribution of vaccine serotypes covered by the first but no longer available 7-valent pneumococcal conjugate vaccine (PCV7) and the 13-valent conjugate vaccine (PCV13) between 2002 and 2016 in adult patients with CAP enrolled into the prospective multicentre study CAPNETZ [ 8 , 9 ]. (ersjournals.com)

The development of pneumococcal conjugate vaccines, in which each of the selected bacterial capsular polysaccharides is coupled to a protein carrier molecule, has been a major advance in the prevention of invasive pneumococcal disease. (who.int)
Since 2006, WHO has recommended that all countries incorporate pneumococcal conjugate vaccines in routine immunization schedules for children aged less than two years with priority being given to their introduction in countries with high child mortality rates and/or high rates of HIV infection. (who.int)
First let me tell you a little about pneumococcal conjugate vaccines and pneumococcal disease. (cdc.gov)
Pneumococcal conjugate vaccines are relatively new type of vaccine that has been shown to be highly effective at preventing disease and in stopping people from acquiring the bacteria in their noses and throats. (cdc.gov)
Pneumococcal conjugate vaccines are now used in infant vaccination programs in most countries around the world. (cdc.gov)
Pneumococcal conjugate vaccines are very specific for preventing certain strains. (cdc.gov)
In 2021, two new pneumococcal conjugate vaccines (PCVs), a 15-valent and a 20-valent PCV (PCV15 and PCV20), were licensed for use in U.S. adults aged ≥18 years by the Food and Drug Administration. (cdc.gov)
Paolo Bonanni of the University of Florence (Italy) added, "Given the effectiveness of key pneumococcal conjugate vaccines, there is a need to enhance access to preventive medicine like these vaccines for all European citizens. (euractiv.com)
Whilst effective pneumococcal conjugate vaccines are not the only solution, when used in association with the judicious use of antibiotics, we have seen positive results. (euractiv.com)
Over the past few years, several pharmaceutical and biopharmaceuticals have enrolled themselves in evaluating candidates of developing pneumococcal conjugate vaccines. (medgadget.com)
Pneumococcal infections can be readily prevented with penicillin prophylaxis and the advent of pneumococcal conjugate vaccines has been a major breakthrough in disease prevention. (biomedcentral.com)
Pneumococcal conjugate vaccines (PCVs), which were primarily developed for vaccination of infants under 2 years of age, have significantly decreased invasive pneumococcal diseases worldwide in all age groups by herd protection effects [ 5 , 6 ]. (ersjournals.com)

Expanded use of recommended vaccines could also prevent more infections. (cdc.gov)
Sarah Gregory] I'm talking today with Dr. Cynthia Whitney, a medical epidemiologist at CDC, about pneumonia vaccines and Streptococcus pneumoniae serotype 12F. (cdc.gov)
This report compiles and summarizes all published recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of pneumococcal vaccines in adults aged ≥19 years in the United States. (cdc.gov)
Current pneumococcal vaccines use the pneumococcal capsular polysaccharides as antigens to generate serotype-specific antibodies, which facilitate serotype-specific clearance of pneumococci through opsonophagocytosis ( 4 ). (cdc.gov)
Our investigational vaccine, Prevenar 13, builds on the scientific foundation of Prevenar and is designed to provide more comprehensive protection against pneumococcal disease, says Emilio A. Emini, Ph.D., Executive Vice President, Vaccines Research and Development, Wyeth Pharmaceuticals. (science20.com)
Based on recent programs to control pneumococcal diseases, experts show that targeted action can assist in preventing ill health and in controlling antibiotic resistance at the same time, when associating the judicious use of antibiotics with prevention in the form of key vaccines. (euractiv.com)
There are more than 90 known strains of pneumococcal disease, and two different vaccines, often called "pneumonia shots," that help combat pneumococcal disease. (mn.us)
Unconjugated as well as conjugated pneumococcal polysaccharide vaccines have been used with success for reducing the rate of pneumococcal infections, especially in adults and children. (medgadget.com)
The high risk of mortality of invasive pneumococcal diseases has spurred research pertaining to this patient cohort, thereby unlocking new prospects in the pneumonia vaccines market. (medgadget.com)
This aside, increasing trend of antibiotic resistance has spurred research in pneumococcal vaccines that can cover against wide range of pneumococci antigens. (medgadget.com)
Particularly, progress made in development of vaccines for the development of invasive pneumococcal diseases has also reinforced lucrative avenues to vaccine manufacturers. (medgadget.com)
Furthermore, hepatitis B vaccines have resulted in a decline in the sequelae of chronic hepatitis B virus infection, and, despite the absence of a specific hepatitis D vaccine, a marked decrease in hepatitis D infections in the United States. (uptodatefree.ir)
Pneumococcal vaccines help protect against some of the more than 90 types of pneumococcal bacteria. (infectioncontroltoday.com)
yet, the number of people who plan on getting the vaccines for each of the infections remains low, according to the NFID announcement today. (infectioncontroltoday.com)
36% were covered by the 7-valent pneumococcal conjugate vaccine, 54% each by PCV-10 and PCV-13, and 72% by the e 23 valent vaccines. (ox.ac.uk)
It is estimated that around a million children less than 5 years old die annually due to invasive infections associated to Streptococcus pneumoniae, even when there are two polysaccharides vaccines in children under 2 years. (univalle.edu.co)
However, PCV10 held the smallest market share of only 8% of pneumococcal vaccines in Germany in 2018 [ 10 ]. (ersjournals.com)

Until 2000, pneumococcal infections caused 60,000 cases of invasive disease each year. (cdc.gov)
In 2019, ABCs estimated there were about 30,300 cases of invasive pneumococcal disease. (cdc.gov)
All types of invasive pneumococcal disease (including DRSP) are included in the national public health surveillance system, National Notifiable Diseases Surveillance System (NNDSS). (cdc.gov)
These surveillance data are used to estimate how many cases of invasive pneumococcal disease (including DRSP) occur each year in the United States. (cdc.gov)
Streptococcus pneumoniae is a leading cause of infectious disease globally. (lu.se)
We used whole-transcriptome shotgun sequencing (RNA-seq) to compare the S. pneumoniae transcriptome in biofilms, bacteria dispersed from biofilms after exposure to IAV, febrile-range temperature, or ATP, and planktonic cells grown at 37°C. Compared with biofilm bacteria, actively dispersed S. pneumoniae, which were more virulent in invasive disease, upregulated genes involved in carbohydrate metabolism. (lu.se)
Pneumococcal disease is an infection caused by a bacterium called Streptococcus pneumoniae (S. pneumoniae) or the pneumococcus. (who.int)
When you add up all these infections, pneumococcal disease is a leading cause of infections and deaths around the world, especially in infants and the elderly. (cdc.gov)
The manuscript we are discussing here talks about how surveillance for pneumococcal infections in Israel found that the new vaccine program was preventing a lot of disease, but they also detected an increase in one of the strains that the vaccine doesn't cover-- serotype 12F. (cdc.gov)
Cynthia Whitney] The surveillance system in Israel was set up by working with all the hospitals in the country--26 of them--to get them to report every time a patient was treated there who had invasive pneumococcal disease. (cdc.gov)
Let me explain what invasive disease is. (cdc.gov)
Invasive disease is a set of illnesses in which pneumococcus is grown from a specimen of blood or spinal fluid collected from a person who is ill. (cdc.gov)
The authors of this report were able to look at how the amount of invasive disease changed after a new pneumococcal conjugate vaccine program began in Israel. (cdc.gov)
The authors found that rates of pneumococcal disease did drop after the new vaccine program began. (cdc.gov)
Before 2021, ACIP recommended 23-valent pneumococcal polysaccharide vaccine (PPSV23) alone (up to 2 doses), or both a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) in combination with 1-3 doses of PPSV23 in series (PCV13 followed by PPSV23), for use in U.S. adults depending on age and underlying risk for pneumococcal disease. (cdc.gov)
Certain persons with pneumococcal colonization might develop invasive pneumococcal disease (IPD) ( 2 ). (cdc.gov)
In adults, pneumococcal pneumonia is the most common type of pneumococcal disease, and pneumococcus is the most common bacterial cause of pneumonia that results in hospitalization ( 3 ). (cdc.gov)
KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of VAXNEUVANCE™ (Pneumococcal 15-valent Conjugate Vaccine) for active immunization for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae in individuals 18 years of age and older. (merck.com)
The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. (merck.com)
and meningitis (infection of the coverings of the brain and spinal cord), as well as non-invasive pneumonia (when pneumococcal disease is confined to the lungs). (merck.com)
While healthy adults can suffer from pneumococcal disease, patient populations particularly vulnerable to infection include older adults such as those 65 years of age and older, people with HIV, and those with certain chronic health conditions. (merck.com)
She continued by outlining how infant vaccination can limit the spread of disease causing pneumococci within a community - particularly for the antibiotic-resistant pneumococci -- by reducing the likelihood of S. pneumoniae transmission between vaccinated children and other unvaccinated members of the community, such as elderly adults. (euractiv.com)
Invasive pneumococcal disease is serious at any age and the high prevalence of resistance to antibiotics in some countries means we need new solutions. (euractiv.com)
They offer real life health care solutions against pneumococcal disease that can save money and more importantly alleviate concerns of families across Europe. (euractiv.com)
According to the World Health Organization (WHO), pneumococcal disease is the leading cause of vaccine-preventable death worldwide in children younger than 5 years and is estimated to cause up to 1 million deaths worldwide in children each year. (euractiv.com)
Pneumococcal disease is complex and describes a group of illnesses, all caused by the bacterium Streptococcus pneumoniae. (euractiv.com)
Pneumococcal disease affects both children and adults, and includes invasive infections such as bacteremia/sepsis and meningitis, as well as pneumonia and acute otitis media. (euractiv.com)
Serogroup 6 is one of the most common causes of invasive pneumococcal disease in unvaccinated populations. (biomedcentral.com)
Treating pneumococcal infections with penicillin and other antibiotics used to be effective, but the disease is becoming more and more resistant to antibiotic treatment, making immunization increasingly important. (mn.us)
Researchers from Europe, Sth Africa and the US have found that exposure to metal fumes not only increases the risk of welders contracting pneumonia but also increases their risk of contracting invasive pneumococcal disease (IPD). (ohsrep.org.au)
The Contribution of Genetic Variation of Streptococcus Pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease. (cdc.gov)
Demand for prevention of invasive pneumococcal disease has helped shape the approaches for manufacturers. (medgadget.com)
For the purposes of national surveillance, "invasive" pneumococcal disease refers only to bacteremia and/or meningitis. (cdc.gov)
Invasive pneumococcal disease (IPD) is a serious bacterial disease. (who.int)
Invasive pneumococcal disease (IPD) is a serious bacterial infection caused by the bacteria Streptococcus pneumoniae and can result in bacteraemia, meningitis and pneumonia. (who.int)
A vaccine programme has been in place in Australia for pneumococcal disease since 1999 when the 23-valent polysaccharide pneumococcal vaccine (23vPPV) was introduced for Aboriginal and Torres Strait Islander adults aged 50 years and over ( Box 2 ). (who.int)
Direct and indirect effects of routine vaccination of children with 7-valent pneumococcal conjugate vaccine on incidence of invasive pneumococcal disease-United States, 1998-2003. (jamanetwork.com)
For the past 30 years, the PPSV23 vaccine (23-valent pneumococcal polysaccharide vaccine), known by the brand name Pneumovax 23, has been the standard protection from invasive pneumococcal disease in adults over 65 years of age. (nih.gov)
At least 90% of the strains that cause invasive disease are present in the 23-valent pneumococcal vaccine. (lookfordiagnosis.com)
Late last year, in response to concerns raised by child health experts, Pharmac amended the national childhood immunisation schedule to include a 13-valent pneumococcal vaccine (PVC-13) in response to rising case numbers of Invasive Pneumococcal Disease ( IPD ). (otago.ac.nz)
Pneumococcal disease is currently the world's number one vaccine-preventable cause of death among infants and children younger than five years of age. (otago.ac.nz)
Home » Infectious Diseases / Bacteria / Viruses » What is pneumococcal disease? (nccmed.com)
What is pneumococcal disease? (nccmed.com)
Pneumococcal disease is a common infection which is mostly mild, but it can also lead to serious health problems. (nccmed.com)
The pneumococcal disease causes the bacterium Streptococcus pneumoniae (S. pneumoniae), which is also known as pneumococcus. (nccmed.com)
Invasive pneumococcal disease in 10 percent of cases is a life-threatening infection that is fatal. (nccmed.com)
Regular vaccinations can prevent many pneumococcal disease types and potential complications. (nccmed.com)
There are two major types of pneumococcal disease: non-invasive and invasive with the less serious being the non-invasive. (nccmed.com)
Pneumococcal disease can cause a mild infection, bronchitis, or a more serious illness. (nccmed.com)
Anyone may develop pneumococcal disease but some people are at greater risk of infection or complications than others. (nccmed.com)
Streptococcus pneumoniae (the pneumococcus) is a common nasopharyngeal commensal that can cause invasive pneumococcal disease (IPD). (uit.no)
Streptococcus pneumoniae is a pathogenic bacterium responsible for invasive pneumococcal disease (IPD) such as meningitis and bacteremia. (elsevierpure.com)
Molecular epidemiology of paediatric invasive pneumococcal disease in southern Spain after the introduction of heptavalent pneumococcal conjugate vaccine. (ox.ac.uk)
The PCV13 vaccine has significantly reduced the incidence of invasive pneumococcal disease, such as pneumococcal pneumonia and meningitis, in children. (pediatric.me)
By using these systems, a model of pneumococcal disease has been assembled. (stjude.org)
Rationale: Streptococcus pneumoniae serotype 3 (SPN3) is a cause of invasive pneumococcal disease and associated with low carriage rates. (ox.ac.uk)
However, for some individuals with chronic liver disease due to the bloodborne pathogens, shared risk factors may result in dual infections with hepatitis B and C or exposure to hepatitis A. Data suggest that the prevalence of hepatitis A infection is higher in patients with chronic liver disease than in the general population [ 3 ]. (uptodatefree.ir)
Furthermore, in patients with chronic liver disease or in recipients of liver transplants, the superimposition of another acute disease (hepatitis virus superinfection, influenza, and pneumococcal infection) may result in higher morbidity and mortality than in individuals without pre-existing liver disease. (uptodatefree.ir)
The impact of hepatitis viruses, pneumococcal disease, and influenza infection in the patient with chronic liver disease will be discussed here. (uptodatefree.ir)
IMPACT OF VACCINE-PREVENTABLE INFECTIONS - Studies of the impact of vaccine-preventable infections (hepatitis A and B, influenza, and pneumococcal disease) in chronic liver disease have been largely restricted to patients with chronic hepatitis B and C, alcohol-associated liver disease, compensated and decompensated cirrhosis, and liver transplant recipients. (uptodatefree.ir)
We provide a systemic overview of genetic variants associated with susceptibility, phenotype and outcome of community acquired pneumococcal pneumonia (CAP) and invasive pneumococcal disease (IPD). (biomedcentral.com)
We identified five studies with a hypothesis free approach of which one resulted in one genome wide significant association in a gene coding for lincRNA with pneumococcal disease susceptibility. (biomedcentral.com)
Studies have identified several host genetics factors influencing risk of pneumococcal disease, but many result in non-reproducible findings due to methodological limitations. (biomedcentral.com)
Invasive pneumococcal disease (IPD) is an infection confirmed by the isolation of Streptococcus pneumoniae from a normally sterile site, while non-invasive pneumococcal disease includes sinusitis, mastoiditis, acute otitis media, and community-acquired pneumonia (CAP). (biomedcentral.com)
In the past 20 years several genetic association studies investigated host genetics in relation to susceptibility and outcome of pneumococcal disease, sometimes showing conflicting results. (biomedcentral.com)
Here we systematically review these studies, perform a meta-analysis and discuss the potential of these findings for understanding the pathophysiological mechanisms of pneumococcal disease. (biomedcentral.com)
Adults with asthma are at increased risk for pneumococcal disease, yet according to a new Centers for Disease Control and Prevention (CDC) study published today in the American Journal of Preventive Medicine , just 54 percent of adults with work-related asthma-asthma triggered by an exposure at work-have been vaccinated against the infection. (infectioncontroltoday.com)
People with work-related asthma are particularly vulnerable to pneumococcal pneumonia," said NIOSH director John Howard, MD. "Vaccination is the best way to prevent pneumococcal disease, including pneumonia, and CDC recommends that all adults with asthma, whether work-related or not, get the pneumococcal polysaccharide vaccine. (infectioncontroltoday.com)
Adults with asthma who get pneumococcal pneumonia are at risk for additional complications including asthma exacerbation and invasive pneumococcal disease. (infectioncontroltoday.com)
Our study found that the vaccination coverage for pneumococcal disease among adults who have ever worked and have asthma falls short of achieving the coverage public health experts recommend," said Katelynn Dodd, MPH, lead author and an epidemiologist in the Respiratory Health Division, NIOSH. (infectioncontroltoday.com)
To increase the number of adults with asthma who are vaccinated against pneumococcal disease, we recommend that healthcare providers verify if their patients who have asthma have received a pneumococcal vaccine and offer the vaccine to those not vaccinated. (infectioncontroltoday.com)
Pneumococcal disease is an infection caused by Streptococcus pneumoniae, which can cause many types of illnesses including ear infections, meningitis, and pneumonia. (infectioncontroltoday.com)
Vaccination is the safest, most effective way to protect yourself from getting pneumococcal disease. (infectioncontroltoday.com)
Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. (biomedcentral.com)
Invasive pneumococcal disease (IPD) and sepsis are responsible for substantial morbidity and mortality worldwide with about 2 million deaths each year [ 4 ]. (biomedcentral.com)
I have encountered patients who developed invasive pneumococcal disease and ended up staying in the ICU for up to two months. (breathinglabs.com)
Occupational exposures to metal fumes have been associated with increased pneumonia risk, but the risk of invasive pneumococcal disease (IPD) has not been characterized previously. (modernet.info)
TY - JOUR T1 - Invasive pneumococcal disease in children 5 years after conjugate vaccine introduction--eight states, 1998-2005. (unboundmedicine.com)
Respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD) (including chronic bronchitis and emphysema), pneumonia and invasive pneumococcal disease, are a major cause of poor health and death for Aboriginal and Torres Strait Islander people. (indigenoushpf.gov.au)
In 2018, respiratory diseases caused an estimated 17,920 years of healthy life lost due to illness and or death (17,920 Disability-Adjusted Life Years or DALY) (excludes acute infections such as influenza) - accounting for 7.5% of the total burden of disease for Indigenous Australians. (indigenoushpf.gov.au)
Invasive non-typhoidal Salmonella in sickle cell disease in Africa: is increased gut permeability the missing link? (biomedcentral.com)
However, in many parts of Africa, especially in individuals who are malnourished, infected with malaria, or have sickle cell disease, the organism causes serious and potentially fatal systemic infections. (biomedcentral.com)
Although a typhoid fever/invasive non-Typhoidal Salmonella (iNTS) disease conjugate vaccine targeting S. enteritidis, S. typhimurium, and S. typhi is currently in Phase 1 clinical trials, prevention of Salmonella infections, particularly those by NTS, remains a major challenge. (biomedcentral.com)
The clinical features of invasive NTS (iNTS) are distinct from those of gastroenteritis or typhoid disease. (biomedcentral.com)
Pneumococcal disease is an illness caused by infection with the bacterium ('germ') Streptococcus pneumoniae. (immunisationcoalition.org.au)
Pneumococcal disease is a leading cause of serious illness among Australian children under two years of age and persons over 70 years of age. (immunisationcoalition.org.au)
Pneumococcal meningitis and pneumococcal septicaemia are both forms of 'Invasive Pneumococcal Disease' (IPD). (immunisationcoalition.org.au)
Invasive pneumococcal disease - particularly septicaemia and meningitis - is a very serious illness. (immunisationcoalition.org.au)
In some people (particularly those at increased risk), the Pneumococcus bacteria invades the body or blood stream causing pneumococcal disease. (immunisationcoalition.org.au)
However, vulnerable people may develop pneumococcal disease. (immunisationcoalition.org.au)
Pneumococcal disease occurs most commonly in the colder months in Australia. (immunisationcoalition.org.au)
When people do get sick with pneumococcal disease, it is rarely possible to be sure where or how they caught their infection. (immunisationcoalition.org.au)
The World Health Organization (WHO) states that pneumococcal disease is the world's number 1 vaccine-preventable cause of death among infants and children younger than 5 years of age. (immunisationcoalition.org.au)
Pneumococcal disease is also an important cause of pneumonia in adults 70 years of age or over. (immunisationcoalition.org.au)
This is due to the lack of coverage of sero-types 1 and 5 that frequently cause invasive disease in our country and Latin America 2 . (univalle.edu.co)
One of the possible ways of action is to introduce the vaccine in high risk populations, low birth weight, that have a much higher incidence of pneumococcal disease compared with normal weight children 3 - 5 . (univalle.edu.co)
A Nationwide Outbreak of Invasive Pneumococcal Disease in Israel Caused by Streptococcus Pneumoniae Serotype 2. (cdc.gov)
Pneumococcal infections are globally the most frequent vaccine-preventable cause of death [ 1 ], and community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae is the main burden of pneumococcal disease in the elderly [ 2 ]. (ersjournals.com)
In adults, the German Standing Committee on Immunization (STIKO) recommends the 23-valent pneumococcal polysaccharide vaccine (PPV23) as routine pneumococcal vaccination for all adults of 60 years and above and for all patients with defined chronic comorbidities predisposing to pneumococcal disease, regardless of age. (ersjournals.com)

Some Streptococcus pneumoniae (pneumococcus) are resistant to one or more antibiotics. (cdc.gov)
DRSP is associated with increased costs compared to infections caused by non-resistant (susceptible) pneumococcus. (cdc.gov)
Streptococcus pneumoniae , or pneumococcus, is an encapsulated Gram-positive bacterium that is the major cause of bacteremia and upper respiratory infections (eg, otitis media and sinusitis) in children and a common cause of serious invasive infections. (medscape.com)
However, individuals that have a properdin deficiency do have a heightened susceptibility to bacterial infections, most notably caused by bacteria within the Neisseria genus, though there have also been studied cases of individuals with recurrent pneumococcus bacteremia as a result of Streptococcus pneumoniae, another species of bacteria from an entirely different phylum. (wikipedia.org)
Streptococcus pneumoniae is a bacteria that is also known as pneumococcus. (cdc.gov)
The main diseases pneumococcus causes are mild infections, like ear and sinus infections, but pneumococcus can also cause severe illnesses like pneumonia and meningitis. (cdc.gov)
Pneumococcal infections are caused by Streptococcus pneumoniae (pneumococcus), a gram-positive, facultative anaerobic bacterium. (cdc.gov)
Pneumococcus can colonize the upper respiratory tract, most commonly in young children, and is transmitted to others through contact with respiratory droplets from a person with pneumococcal colonization in the upper respiratory tract ( 1 ). (cdc.gov)
Human Infection Challenge with Serotype 3 Pneumococcus. (ox.ac.uk)
Streptococcus pneumoniae ) OR ( S. pneumoniae ) OR pneumococcal OR pneumococcus) AND (polymorphisms OR polymorphism OR (genetic variant) OR (genetic variants) OR (genetic association study) OR (single nucleotide polymorphism) OR (single nucleotide polymorphisms) OR SNP OR SNPs OR genotype OR genotypes) without language restrictions and with search date cut offs between Jan 1, 1983 and Jul 4, 2018. (biomedcentral.com)
Streptococcus pneumoniae , or pneumococcus, is a Gram-positive, spherical bacteria, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), facultative anaerobic member of the genus Streptococcus. (ntu.edu.sg)
Streptococcus pneumoniae (pneumococcus) is a major cause of meningitis, pneumonia, and bacteremia, especially among young children and older adults. (unboundmedicine.com)
Morbidity and mortality weekly report JO - MMWR Morb Mortal Wkly Rep VL - 57 IS - 6 N2 - Streptococcus pneumoniae (pneumococcus) is a major cause of meningitis, pneumonia, and bacteremia, especially among young children and older adults. (unboundmedicine.com)

Pneumococcal bacteremia was termed "pneumococcal fever" during the 1970s and 1980s, when S pneumoniae was recovered in approximately 5% of blood cultures from young febrile children with mild upper respiratory tract changes (see the table below). (medscape.com)
Severe infections, predominantly meningitis, occur in fewer than 6% of pneumococcal occult bacteremia cases-a figure that is much lower than the 50% reported with meningococcal bacteremia and the 20% reported with H influenza . (medscape.com)
Because of the extremely low yield, blood cultures are no longer routinely warranted in children aged 3-36 months who have no obvious source of infection, and empiric treatment of occult bacteremia is no longer appropriate. (medscape.com)
For patients with focal infection and pneumococcal bacteremia, treatment of the focal infection and monitoring for improvement are standard. (medscape.com)
For outpatients with proven pneumococcal bacteremia, reevaluation of their clinical status and identification of any new focus of infection is essential. (medscape.com)
Occult pneumococcal bacteremia is most common in children aged 3-36 months, an age at which children no longer have maternal IgG but have not yet developed their own protective antibodies. (medscape.com)
For this system, invasive pneumococcal infection refers only to meningitis and bacteremia identified by isolation of S. pneumoniae from cerebrospinal fluid (CSF) or blood, respectively. (cdc.gov)
A confirmed case of invasive DRSP is defined as either meningitis or bacteremia in which S. pneumoniae cultured from CSF or blood is identified as nonsusceptible (using National Committee for Clinical Laboratory Standards {NCCLS} methods and breakpoints) to antimicrobial drugs currently approved for treating pneumococcal infections. (cdc.gov)
A probable case of invasive DRSP is defined as either meningitis or bacteremia in which S. pneumoniae cultured from CSF or blood is identified as nonsusceptible by oxacillin screening (i.e., zone size less than or equal to 19 mm) and no further antimicrobial susceptibility testing has been performed. (cdc.gov)
Infection can be invasive and result in pneumococcal pneumonia, pneumococcal bacteremia (bacterial infection of the blood), or pneumococcal meningitis. (who.int)
The bacteria Streptococcus pneumoniae is responsible for pneumococcal infections causing otitis media, bacteremia, pneumonia, and meningitis. (medgadget.com)
Pneumococci may cause many clinical syndromes depending on the site of infection (e.g. otitis media, pneumonia, bacteremia, or meningitis). (cdc.gov)
RESULTS: Out of 42 cases of invasive pneumococcal diseases studied admitted diagnoses included pneumonia, febrile seizure, bacteremia or septicemia, meningitis, acute gastroenteritis and glomerulonephritis. (ox.ac.uk)

According to Active Bacterial Core surveillance (ABCs) data, up to 40% of these infections were caused by pneumococcal bacteria that were resistant to at least one antibiotic. (cdc.gov)
Available data show that pneumococcal bacteria are resistant to one or more antibiotics in more than 30% of cases. (cdc.gov)
We used whole-transcriptome shotgun sequencing (RNA-seq) to compare the S. pneumoniae transcriptome in biofilms, bacteria dispersed from biofilms after exposure to IAV, febrile-range temperature, or ATP, and planktonic cells grown at 37°C. Compared with biofilm. (lu.se)
In fact, this strategy brings at least a 2-fold decrease in antimicrobial resistance even to bacteria commonly responsible for widespread infections in children and adults," she explained. (euractiv.com)
In most instances, it is more common for these viruses or bacteria to cause some other illness, such as an ear infection, pneumonia or other illness. (mn.us)
The Streptococcus pneumoniae bacteria kills more people in the United States each year than all other vaccine-preventable diseases combined. (mn.us)
Recent estimates of the burden of antimicrobial resistance suggest that there are approximately 700,000 deaths worldwide every year due to infections with antimicrobial resistant bacteria, with nearly 50,000 of these deaths occurring in the United States and Europe (CDC. (pids.org)
Some of the most worrisome antibiotic-resistant bacteria are MDR Enterobacterales , which includes species like E. coli and Klebsiella pneumoniae . (pids.org)
Characteristics of mixed infections from two or more respiratory viruses or between viruses and bacteria in cases of pneumonia. (biodonostia.org)
S. The pneumoniae bacteria are normal in children's throats and noses. (nccmed.com)
For example , when a person with the infection coughs or sneezes, bacteria may spread through droplets in the air. (nccmed.com)
Patients who contract this bacteria can develop a severe infection as this bacteria may gain entry into the bloodstream. (breathinglabs.com)
In Europe and the US, Streptococcus pneumoniae is the leading cause but in Africa, enteric bacteria, such as Salmonella are most common. (biomedcentral.com)

Due to a heightened susceptibility to Neisseria bacterium, individuals with properdin deficiency are far more likely to succumb to bacterial infection such as meningitis, resulting in inflammation of the brain and spinal cord, which causes severe headaches, fevers, and neck stiffness, and may result in further development of other meningococcal diseases and extreme complications such as sepsis. (wikipedia.org)
Other common non invasive diseases are otitis media (middle-ear infection) and sinusitis. (who.int)
Evidence shows this strategy has worked in at least one risk group - young children - in preventing pneumococcal diseases like pneumococcal meningitis, pneumonia or middle ear infection1. (euractiv.com)
The company is developing its pneumococcal vaccine for treating invasive diseases and otitis media in healthy infant populations. (medgadget.com)
Researchers plan to see if a higher dose of a pneumococcal vaccine will create a stronger immune response in older adults who received an earlier generation vaccine against pneumonia and other pneumococcal diseases. (nih.gov)
Dr. Marimón has been Head of the Respiratory Infection and Antimicrobial Resistance Group of the Infection Diseases Area of the Biodonostia HRI since 2017. (biodonostia.org)
Invasive pneumococcal diseases (IPDs) are more severe than the non-invasive type and occur within a major organ, or in the blood of a person. (nccmed.com)
A doctor should ask about the signs while diagnosing pneumococcal diseases, and conduct a physical examination. (nccmed.com)
Secondary HLH can be triggered by infections, autoimmune diseases, and malignant diseases. (elsevierpure.com)
The Pneumococcal Conjugate Vaccine (PCV13) is a crucial vaccine for children designed to protect against infections caused by the Streptococcus pneumoniae bacterium, including pneumonia, meningitis, and other serious diseases. (pediatric.me)
PCV13 is a safe and effective vaccine that helps protect against diseases caused by certain strains of Streptococcus pneumoniae. (pediatric.me)
It's crucial for parents and caregivers to follow the recommended vaccination schedule for PCV13 to ensure that children receive the necessary doses to build immunity against invasive pneumococcal diseases. (pediatric.me)
Data on the impact of acute viral hepatitis A and B, influenza, and pneumococcal infection on other liver diseases are sparse. (uptodatefree.ir)
ABSTRACT The aim of this prospective study in Morocco was to investigate the causes of invasive bacterial diseases in children in order to inform antibiotic therapy and vaccine choices. (who.int)
Of 238 children aged 5 years admitted to the Children's Hospital of Casablanca for invasive diseases over a 12-month period, 185 were diagnosed with bacterial infection: 76 had chest-X-ray-confirmed pneumonia, 59 had meningitis and 50 had sepsis. (who.int)
Clinical profile of invasive pneumococcal diseases in Patan Hospital, Nepal. (ox.ac.uk)

Sarah Gregory] After the PCV vaccine was introduced in Israel in 2009, there was apparently an increase in Streptococcus pneumoniae serotype 12F. (cdc.gov)
In addition, they did special DNA fingerprinting of the pneumococcal serotype 12F strains to see if the strains were related to each other genetically or to other serotype 12F strains around the globe. (cdc.gov)
the S. pneumoniae isolates from these two patients belonged to the non-vaccine serotype 19B and serotype 19F and demonstrated in vitro resistance to penicillin and erythromycin. (johnshopkins.edu)
We herein report a rare case of a previously healthy boy with secondary HLH complicating IPD of serotype 23A, which is not included in the pneumococcal 13-valent conjugate vaccine (PCV-13). (elsevierpure.com)
The serotype of the isolated S. pneumoniae was 23A, which is not included in PCV-13. (elsevierpure.com)
As the PUAT does not allow serotype discrimination, data on serotype distribution in adult non-bacteraemic pneumococcal CAP patients are sparse [ 4 ]. (ersjournals.com)

The bacterium Streptococcus pneumoniae can cause a type of pneumonia called pneumococcal pneumonia. (nih.gov)

To determine the incidence and prevalence of DRSP, the total number of invasive site isolates tested (i.e., denominator data) must be determined. (cdc.gov)
Denominator data will be essential for providing relevant clinical information to physicians and other health-care providers (see Goal III, Objectives C and D). For laboratories with computerized data management, all invasive site isolates can be reported in the same manner as previously described. (cdc.gov)
data would include the total number of invasive site isolates tested by age group (less than 6 years of age, 6-17 years, and greater than or equal to 18 years of age) and anatomic collection site (i.e. (cdc.gov)
NCCLS recommends that all invasive S. pneumoniae isolates that are found to be "possibly resistant" to beta-lactams (i.e., an oxacillin zone size of less than 20mm) by oxacillin screening should undergo further susceptibility testing using a quantitative MIC method acceptable for penicillin, extended spectrum cephalosporins, and other drugs as clinically indicated. (cdc.gov)
Identification of pneumococcal isolates from blood or cerebrospinal fluid samples was done by routine culture methods. (johnshopkins.edu)
The nationwide Active Bacterial Core pneumococcal surveillance report from 2018 found that 4.7% of invasive pneumococcal isolates were resistant or intermediate to penicillin and 2.6% were resistant or intermediate to cefotaxime. (pids.org)

Economic evaluations of childhood pneumococcal conjugate vaccination - a review (2002-2006) Vaccine 25 (2007) 1355-1367. (euractiv.com)
National and state surveys show large disparities in pneumococcal vaccination status among Whites, Blacks and Latinos aged ≥ 65. (biomedcentral.com)
The purpose of this study is to determine whether there is any difference in the validity of self-report for pneumococcal vaccination by race/ethnicity that might contribute to the substantial disparities observed in population-level coverage estimates. (biomedcentral.com)
The results of this study suggest that differential self-report error, i.e., summative effect of over-reporting and under-reporting within a race-ethnic group, may contribute to the size and direction of race-ethnic disparities in pneumococcal vaccination observed in surveys. (biomedcentral.com)
Healthy People 2010 Objectives call for ≥ 90% of adults aged ≥ 65 to have had a pneumococcal vaccination [ 3 ], and pneumococcal vaccination of adults in this age group has been made a performance measure for the 2004 Health Plan Employer Data and Information Set (HEDIS) sponsored by the National Committee for Quality Assurance (NCQA). (biomedcentral.com)
National surveys have found that while pneumococcal vaccination coverage has significantly increased over the years, vaccination rates of Black and Hispanic/Latino seniors are 17 to 30 percentage points lower than for Whites [ 4 - 6 ]. (biomedcentral.com)
Estimates of pneumococcal vaccination coverage are based on self-reported information from state (e.g. (biomedcentral.com)
Influence of child vaccination with the new 13-valent vaccine on invasive infections and on the naso-pharyngeal carriage in the early years of life. (biodonostia.org)
Vaccination helps prevent serious illnesses, hospitalization, and death associated with Streptococcus pneumoniae infections. (pediatric.me)
PCV13 vaccination is primarily recommended for infants and children, as they are most at risk for severe pneumococcal infections. (pediatric.me)
Timely and complete vaccination is essential for protecting children and the community from these potentially severe infections. (pediatric.me)
See "Hepatitis A virus infection: Treatment and prevention" and "Hepatitis B virus immunization in adults" and "Seasonal influenza vaccination in adults" and "Pneumococcal vaccination in adults" and "Meningococcal vaccination in children and adults" . (uptodatefree.ir)
The Advisory Committee on Immunization Practices recommends a pneumococcal polysaccharide vaccination for all adults 19 through 64 years old with asthma. (infectioncontroltoday.com)
84% had complete Hib vaccination schedules, and 87% had complete pneumococcal under the age of 5 in a tertiary pediatric hospital in vaccination schedules for age. (bvsalud.org)

In addition, ACIP recommends use of either a single dose of PCV20 or ≥1 dose of PPSV23 for adults who have started their pneumococcal vaccine series with PCV13 but have not received all recommended PPSV23 doses. (cdc.gov)
This objective tracks the incidence of pneumococcal infections among adults aged 65 years and older using ABCs. (cdc.gov)
A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) part II: immunization of adults. (jamanetwork.com)
The study supported by the National Institutes of Health will compare two dosages of a pneumococcal vaccine approved for children ages 6 weeks to 5 years, and adults 50 and older. (nih.gov)
Children younger than 5 and adults older than 65 are most susceptible to becoming ill from pneumococcal pneumonia. (nih.gov)
The newer PCV13 vaccine (13-valent pneumococcal conjugate vaccine), known by the brand name Prevnar 13, protects against bacterial pneumonia and other invasive pneumococcal illnesses in children, but the efficacy and most effective dosage in adults is unknown. (nih.gov)
CDC recommends all adults 19 through 64 years old with asthma get the pneumococcal polysaccharide vaccine. (infectioncontroltoday.com)
CDC's National Institute for Occupational Safety and Health (NIOSH) researchers found that adults with work-related asthma were more likely to have reported receiving a pneumococcal vaccine than adults with non-work-related asthma - 54 percent compared with 35 percent, respectively. (infectioncontroltoday.com)
Among adults with work-related asthma, pneumococcal vaccine coverage was lowest among Hispanics (36 percent), those without health insurance (39 percent), and adults ages 18 to 44 years (42 percent). (infectioncontroltoday.com)
The 23-valent pneumococcal polysaccharide vaccine (PPV23) has been recommended to risk-groups and adults aged ≥65 years since 1996. (biomedcentral.com)

Areas of medical therapeutics applicable to this work include pneumococcal vaccine design, intervention in gram-positive sepsis/meningitis, new antibiotic development strategies, and interruption of the spread of genetic elements responsible for antibiotic resistance. (stjude.org)
Pneumonia, sepsis, meningitis, and empyema due to Streptococcus pneumoniae is a major cause of morbidity and mortality. (biomedcentral.com)
Streptococcus pneumoniae is the main cause of community acquired pneumonia and meningitis in children and the elderly, and of sepsis in those infected with HIV. (ntu.edu.sg)

Hanna Nohynek of the University of Tampere (Finland) explained that there can be a synergy between national programmes to control unnecessary antibiotic use and immunization programs with an effective pneumococcal conjugate vaccine. (euractiv.com)
CDC's Advisory Committee on Immunization Practices (ACIP) recommends a single dose of pneumococcal polysaccharide vaccine for all people 65 years and older [ 2 ]. (biomedcentral.com)
There have been some reports of the impact of the pneumococcal vaccine since its introduction into the Australian immunization schedule and the potential benefits that may be offered by the 13vPVC. (who.int)
The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the childhood immunization program in July 2006, and was replaced by the 13-valent vaccine (PCV13) in 2011. (biomedcentral.com)

S. pneumoniae is a common cause of acute otitis media, community-acquired pneumonia, and sinusitis in children. (pids.org)
Non-invasive pneumococcal infection: otitis and conjunctivitis. (biodonostia.org)
Streptococcus pneumoniae can also cause ear infections, including otitis media. (pediatric.me)
Otitis media - middle ear infection. (immunisationcoalition.org.au)

CDC's Antibiotic Resistance Threats in the United States, 2019 includes the latest national death and infection estimates that underscore the continued threat of antimicrobial resistance. (cdc.gov)
In this study, we defined the population biology of serogroup 6 Streptococcus pneumoniae collected in China and their antibiotic resistance profiles. (biomedcentral.com)
In more than 30% of infections, the isolate will be resistant to one or more clinically useful antibiotics (CDC, Antibiotic Resistance Threat Report , 2019. (pids.org)

Invasive penicillin-resistant pneumococcal infections: a prevalence and historical cohort study. (cdc.gov)
In Belgium for example, the prevalence of antibiotic-resistant pathogens, in particular, penicillin-nonsusceptible S. pneumoniae, has decreased since the start of the national public campaigns. (euractiv.com)
While Streptococcus pyogenes remains highly susceptible to beta-lactam antibiotics, over the past decade increasing prevalence of clindamycin and macrolide resistance are being reported worldwide. (pids.org)
Concern about the rising prevalence of resistant pneumococcal strains is increasing, but the clinical relevance is uncertain. (lookfordiagnosis.com)
Conclusion: The overall prevalence of bacterial infections was high with many being resistant to commonly pre-scribed antimicrobial agents. (bvsalud.org)

The organism also causes many types of pneumococcal infections other than pneumonia. (ntu.edu.sg)

There are at least 90 different strains of Streptococcus pneumoniae. (immunisationcoalition.org.au)

Resistance of invasive pneumococcal strains to penicillin, cefotaxime, and ceftriaxone has increased over the past few years. (elsevierpure.com)
CONCLUSIONS: Penicillin is still the most effective antibiotic for streptococcal infection in our study. (ox.ac.uk)

Streptococcus pneumoniae can cause a range of illnesses, depending on which part of the body is infected. (immunisationcoalition.org.au)

Streptococcus pneumoniae grew in 38 blood samples, 5 cerebrospinal fluid and 3 pleural fluids. (ox.ac.uk)

Background: Bacterial infections are an important cause of maternal morbidity and mortality especially in re-source limited countries such as Ethiopia. (bvsalud.org)
The major bacterial infections include urinary tract infections, septice-mia and endometritis. (bvsalud.org)
Being in the first trimester of pregnancy and having a history of diabetes mellitus were strongly associated with the presence of bacterial infections. (bvsalud.org)

People with pneumococcal infections who recently used antibiotics are more likely to have a resistant infection than those who have not. (cdc.gov)
Providers must remember that every antibiotic course exposes each patient's entire microbiome to that drug and strive to use antibiotics only when needed and to use the narrowest spectrum and shortest duration needed for the patient's infection. (pids.org)
To establish the mechanisms of Streptococcus pyogenes resistance to macrolide, tetracycline and fluoroquinolone antibiotics. (biodonostia.org)
Unless the infection may be serious, physicians are likely to initiate treatment and recommend a course of antibiotics before the results of such tests are obtained. (nccmed.com)

To estimate the economic impact of the introduction of heptavalent pneumococcal conjugate vaccine (PCV-7) in high risk populations of Colombia. (univalle.edu.co)
The introduction of the Heptavalent Pneumococcal Conjugate Vaccine in populations of high risk is highly cost effective in Colombia. (univalle.edu.co)

Haemophilus influenzae type b (Hib) was once the most common cause of bacterial infection in children. (mn.us)
Streptococcus pneumoniae was the most common pathogen identified ( n = 24), followed by Neisseria meningitidis ( n = 18, all group B) and Haemophilus influenzae ( n = 11). (who.int)
Streptococcus pneumoniae était l'agent pathogène le plus fréquemment identifié ( n = 24), suivi par Neisseria meningitidis ( n = 18, ensemble du groupe B) puis par Haemophilus influenzae ( n = 11). (who.int)
Streptococcus pneumoniae , Haemophilus The study was conducted between Sep- performed with nitrocefin-impregnated influenzae and Neisseria meningitidis infec- tember 2007 and August 2008 at the disks (Cefinase, Becton-Dickinson). (who.int)

The proposed surveillance system is intended to monitor only invasive pneumococcal infections and their antimicrobial susceptibility patterns. (cdc.gov)
Cynthia Whitney] Overall, the surveillance program identified over 4500 episodes of invasive pneumococcal infections in Israel between the middle of 2009 and the middle of 2016. (cdc.gov)
Although S. pneumoniae infections involving other normally sterile sites such as joint, pleural, or peritoneal fluid are sometimes considered invasive, these infections are not intended for inclusion under this surveillance system. (cdc.gov)
increased respiratory rate or neurological symptoms were recruited, (as part of the Alliance for Surveillance of Invasive Pneumococci - ASIP - project) from January 2011 to March 2013. (johnshopkins.edu)
2018. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae , 2018. (pids.org)

Sinusitis - infection of the sinuses (air-filled cavities in the face). (immunisationcoalition.org.au)

Streptococcus pneumoniae resides asymptomatically in healthy carriers typically colonizing the respiratory tract, sinuses, and nasal cavity. (ntu.edu.sg)
Streptococcus pneumoniae commonly resides asymptomatically in the nasopharyngeal (NP) cavity of healthy individuals but can cause life-threatening pulmonary and systemic infections, particularly in the elderly. (umassmed.edu)

abstract = "This statement provides guidelines for therapy of children with serious infections possibly caused by Streptococcus pneumoniae. (elsevierpure.com)

Nasopharyngeal colonization occurs in biofilms and precedes infection. (lu.se)
NP colonization results in a robust immune response that protects against invasive infections. (umassmed.edu)

As a significant human pathogenic bacterium S. pneumoniae was recognized as a major cause of pneumonia in the late 19th century, and is the subject of many humoral immunity studies. (ntu.edu.sg)

S. pneumoniae can infect the upper respiratory tract and spread to the lungs, blood, middle ear or nervous system. (nih.gov)

Emergence of drug resistant Streptococcus pneumoniae may by associated with severe clinical outcomes. (johnshopkins.edu)
The clinical presentation of the joint infection is often atypical, leading to diagnostic wanderings. (lookfordiagnosis.com)

Main objective: to study the epidemiology of respiratory infection. (biodonostia.org)
The aim of our study is to describe the epidemiology, the treatment and the evolution of HUS after invasive pneumococcal infections in Tunisia. (iomcworld.com)

Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)

How common drug-resistant Streptococcus pneumoniae (DRSP) is varies throughout the United States. (cdc.gov)
People who attend or work at childcare centers are at increased risk for infection with DRSP. (cdc.gov)

The major focus of this research is the molecular pathogenesis of invasion and inflammation induced by Streptococcus pneumoniae, the leading invasive bacterial pathogen of children. (stjude.org)

These findings suggest that NP exposure elicits extended protection against pneumococcal lung infection by generating long-lived CD138(+) ASC and that the protective efficacy of these responses declines with age. (umassmed.edu)

The report identifies drug-resistant S. pneumoniae as a serious threat. (cdc.gov)
Drug resistant S. pneumoniae is considered a serious by the CDC, with an estimated 2 million infections each year. (pids.org)

There are 90 known capsular antigenic types of Streptococcus pneumoniae . (who.int)

Twelve patients with pneumococcal arthritis are described. (lookfordiagnosis.com)

However, influenza A virus (IAV) infection releases virulent pneumococci from biofilms in vitro and in vivo. (lu.se)
Infections caused by the influenza virus. (biodonostia.org)
For example, patients who are vaccinated against pneumococcal pneumonia as well as against seasonal influenza. (breathinglabs.com)

It often causes meningitis but it can also cause bloodstream infections, pneumonia, joint infections, and other illness. (mn.us)
While this vaccine protects against pneumococcal meningitis and bloodstream infections, it is unclear how well it protects against bacterial pneumococcal pneumonia. (nih.gov)

No salient antibiotic-resistant clones were isolated among the serogroup 6 S. pneumoniae . (biomedcentral.com)
Since the 1980s, antibiotic-resistant infections have become increasingly common. (pids.org)
Reports of failures of cefotaxime or ceftriaxone in the treatment of children with meningitis caused by resistant S pneumoniae necessitates a revision of Academy recommendations. (elsevierpure.com)
For nonmeningeal infections, modifications of the initial therapy need to be considered only for patients who are critically ill and those who have a severe underlying or potentially immunocompromising condition or patients from whom a highly resistant strain is isolated. (elsevierpure.com)
Because vancomycin is the only antibiotic to which all S pneumoniae strains are susceptible, its use should be restricted to minimize the emergence of vancomycin-resistant organisms. (elsevierpure.com)
The emergence of antibiotic resistant pathogens has caused a serious world-wide problem in infection treatments in recent years. (uit.no)
One of these pathogens is the methicillin-resistant Staphylococcus aureus (MRSA) which is a major cause of skin and soft tissue infections. (uit.no)
Abs were necessary and sufficient for protection because Ab-deficient muMT mice did not develop postexposure protection, only becoming resistant to lung infection after transfer of immune sera from NP-exposed mice. (umassmed.edu)

Anatomy7

Organisms25

Diseases22

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes18

Anthropology, Education, Sociology and Social Phenomena1

Information Science3

Named Groups1

Health Care4

Serotypes25

Conjugate vaccines12

Vaccines17

Disease99

Pneumococcus13

Bacteremia13

Bacteria13

Diseases16

Serotype6

Bacterium Streptococcus pneumoniae1

Isolates6

Vaccination14

Adults10

Sepsis3

Immunization4

Otitis4

Antibiotic resistance3

Prevalence5

Types of pneumococcal1

Strains of Streptococcus pneumoniae1

Penicillin2

Illnesses1

Cerebrospinal fluid1

Bacterial infections3

Antibiotics4

Heptavalent Pneumococcal Conjuga2

Haemophilus4

Surveillance5

Sinusitis1

Resides asymptomatically2

Abstract1

Colonization2

Pathogenic bacterium1

Upper respi1

Clinical2

Epidemiology2

Prevention1

DRSP2

Pathogen1

Protection against pneumococcal1

Drug-resistant2

Capsular1

Patients with pneumococcal1

Influenza3

Bloodstream2

Resistant8