Intrinsic and extrinsic apoptosis pathways of apoptosis. Medical search. Frequent questions

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Anatomy29

Cell Line, Tumor Mitochondria Tumor Cells, Cultured Cells, Cultured Cell Line Jurkat Cells HeLa Cells HL-60 Cells Epithelial Cells Endoplasmic Reticulum Cell Nucleus U937 Cells Fibroblasts Neurons T-Lymphocytes Mitochondrial Membranes Cell Line, Transformed K562 Cells HCT116 Cells Hepatocytes HT29 Cells Macrophages Lymphocytes Cytosol Myocytes, Cardiac Endothelial Cells Thymus Gland Intracellular Membranes Neutrophils

Organisms10

Mice, Inbred C57BL Mice, Knockout Mice, Nude Mice, Transgenic Thalictrum Rats, Sprague-Dawley Mice, Inbred BALB C Adenoviridae Rats, Wistar Mice, SCID

Diseases12

Necrosis Neoplasms Colonic Neoplasms Disease Models, Animal Prostatic Neoplasms Lung Neoplasms Adenocarcinoma Breast Neoplasms Carcinoma, Hepatocellular Neuroblastoma Cell Transformation, Neoplastic Melanoma

Chemicals and Drugs129

Caspase 8 Receptors, Death Domain Caspases Caspase 3 Death Domain Receptor Signaling Adaptor Proteins Proto-Oncogene Proteins c-bcl-2 TNF-Related Apoptosis-Inducing Ligand Apoptosis Regulatory Proteins Antigens, CD95 Caspase 9 bcl-2-Associated X Protein Inhibitor of Apoptosis Proteins Cytochromes c X-Linked Inhibitor of Apoptosis Protein Caspase Inhibitors CASP8 and FADD-Like Apoptosis Regulating Protein bcl-X Protein Tumor Suppressor Protein p53 Fas Ligand Protein BH3 Interacting Domain Death Agonist Protein Apoptosis Inducing Factor Caspase 7 Apoptotic Protease-Activating Factor 1 Amino Acid Chloromethyl Ketones Annexin A5 Antineoplastic Agents Cysteine Proteinase Inhibitors Proto-Oncogene Proteins Poly(ADP-ribose) Polymerases bcl-2 Homologous Antagonist-Killer Protein Reactive Oxygen Species RNA, Small Interfering Fas-Associated Death Domain Protein Myeloid Cell Leukemia Sequence 1 Protein Enzyme Inhibitors Cytochrome c Group Tumor Necrosis Factor-alpha Caspase 2 Staurosporine Receptors, TNF-Related Apoptosis-Inducing Ligand bcl-Associated Death Protein RNA, Messenger Carrier Proteins Membrane Glycoproteins NF-kappa B Antineoplastic Agents, Phytogenic Proto-Oncogene Proteins c-akt Receptors, Tumor Necrosis Factor Neoplasm Proteins Caspase 1 Protein-Serine-Threonine Kinases Membrane Proteins Cysteine Endopeptidases Nitrophenols Etoposide Intracellular Signaling Peptides and Proteins Tumor Suppressor Proteins DNA-Binding Proteins Proteins Cyclin-Dependent Kinase Inhibitor p21 Sesquiterpenes, Eudesmane Ceramides Oligopeptides Transcription Factors Sulfonamides Mitochondrial Proteins Adaptor Proteins, Signal Transducing Doxorubicin Caspase 12 Cell Cycle Proteins Luteolin Mitogen-Activated Protein Kinases Biphenyl Compounds Plant Extracts p38 Mitogen-Activated Protein Kinases MAP Kinase Kinase Kinase 5 Hydrogen Peroxide Phosphatidylinositol 3-Kinases Nuclear Proteins Propidium Culture Media, Serum-Free Recombinant Proteins Transcription Factor CHOP Phosphatidylserines Cycloheximide Caspase 6 Microtubule-Associated Proteins Protein Synthesis Inhibitors Proto-Oncogene Proteins c-myc MAP Kinase Kinase 4 Acetylcysteine Oligonucleotides, Antisense Antioxidants Tetrazolium Salts DNA Antibiotics, Antineoplastic DNA Primers Cyclins Flavonoids Glutathione Mitogen-Activated Protein Kinase 8 Receptors, Tumor Necrosis Factor, Type I Extracellular Signal-Regulated MAP Kinases Nucleic Acid Synthesis Inhibitors Recombinant Fusion Proteins Cisplatin Caspase 10 Oxides Chromones Morpholines Proteasome Endopeptidase Complex E2F1 Transcription Factor Sphingomyelin Phosphodiesterase Oxidants Pyrazines Arsenicals Protein Kinase Inhibitors Indoles Imidazoles Tumor Necrosis Factors Boronic Acids Proto-Oncogene Proteins c-mdm2 Mitogen-Activated Protein Kinase Kinases Thiazoles Curcumin Nitric Oxide Histone Deacetylase Inhibitors Hydroxamic Acids Piperazines

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

In Situ Nick-End Labeling Blotting, Western Flow Cytometry Transfection Reverse Transcriptase Polymerase Chain Reaction Models, Biological Immunohistochemistry Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays Immunoblotting Gene Expression Profiling Microscopy, Fluorescence Disease Models, Animal Culture Media, Serum-Free Gene Knockdown Techniques Immunoprecipitation Microscopy, Confocal Cell Count

Phenomena and Processes49

Apoptosis Signal Transduction DNA Fragmentation Cell Survival Enzyme Activation Membrane Potential, Mitochondrial Cell Proliferation Cell Cycle Genes, bcl-2 Cell Death Transfection Down-Regulation Dose-Response Relationship, Drug Cell Division Time Factors Gene Expression Regulation, Neoplastic Up-Regulation Phosphorylation DNA Damage Drug Synergism Drug Resistance, Neoplasm Oxidative Stress RNA Interference Gene Expression Regulation Necrosis Gene Expression Mutation Protein Binding Protein Transport Protein Structure, Tertiary Base Sequence Amino Acid Sequence Cell Differentiation Membrane Potentials Cytoprotection Genes, p53 Autophagy MAP Kinase Signaling System Gamma Rays Cell Cycle Checkpoints Endoplasmic Reticulum Stress G1 Phase Transcription, Genetic G2 Phase Gene Silencing Cell Growth Processes Radiation Tolerance Cell Count Mitosis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Caspase 8 Apoptosis Cell Line, Tumor Receptors, Death Domain Caspases Caspase 3 Death Domain Receptor Signaling Adaptor Proteins Proto-Oncogene Proteins c-bcl-2 TNF-Related Apoptosis-Inducing Ligand Apoptosis Regulatory Proteins Signal Transduction Antigens, CD95 Caspase 9 bcl-2-Associated X Protein Inhibitor of Apoptosis Proteins Cytochromes c Mitochondria DNA Fragmentation X-Linked Inhibitor of Apoptosis Protein In Situ Nick-End Labeling Caspase Inhibitors Cell Survival CASP8 and FADD-Like Apoptosis Regulating Protein bcl-X Protein Tumor Suppressor Protein p53 Fas Ligand Protein Enzyme Activation BH3 Interacting Domain Death Agonist Protein Apoptosis Inducing Factor Membrane Potential, Mitochondrial Tumor Cells, Cultured Cells, Cultured Caspase 7 Apoptotic Protease-Activating Factor 1 Amino Acid Chloromethyl Ketones Annexin A5 Blotting, Western Antineoplastic Agents Cysteine Proteinase Inhibitors Proto-Oncogene Proteins Poly(ADP-ribose) Polymerases Cell Proliferation Cell Line bcl-2 Homologous Antagonist-Killer Protein Flow Cytometry Cell Cycle Reactive Oxygen Species Jurkat Cells Genes, bcl-2 RNA, Small Interfering Cell Death Fas-Associated Death Domain Protein Myeloid Cell Leukemia Sequence 1 Protein Transfection Down-Regulation Enzyme Inhibitors Cytochrome c Group Tumor Necrosis Factor-alpha Caspase 2 Staurosporine Dose-Response Relationship, Drug Receptors, TNF-Related Apoptosis-Inducing Ligand bcl-Associated Death Protein Cell Division Mice, Inbred C57BL Time Factors Reverse Transcriptase Polymerase Chain Reaction Gene Expression Regulation, Neoplastic RNA, Messenger Up-Regulation Phosphorylation Carrier Proteins Membrane Glycoproteins DNA Damage NF-kappa B Antineoplastic Agents, Phytogenic Drug Synergism Proto-Oncogene Proteins c-akt Drug Resistance, Neoplasm Receptors, Tumor Necrosis Factor HeLa Cells HL-60 Cells Mice, Knockout Models, Biological Neoplasm Proteins Oxidative Stress Caspase 1 RNA Interference Gene Expression Regulation Protein-Serine-Threonine Kinases Membrane Proteins Cysteine Endopeptidases Necrosis Nitrophenols Etoposide Intracellular Signaling Peptides and Proteins Epithelial Cells Immunohistochemistry Gene Expression Tumor Suppressor Proteins

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