PenicillinAntibioticsCleocinInjectionLincomycinIntramuscularVancomycinImmunoglobulinContinuous intravenous infusionInhibits bacterial protein synthesisResistance to clindamycinInfusionWeeks of intravenousCommonly used intravenousVaginalContains clindamycin phosphateInfectionsFluidsTopicalMeropenemMetronidazolePrescribe clindamycinBacteriaPlus clindamycinForm of clindamycinAntibiotic treatmentLinezolidGentamicinActive clindamycinTreatmentIsolatesCefazolinRifampinOrallyDoxycyclineMRSAOralVitroTherapyEquivalentErythromycinDrugContrastConcentrationsMalariaSolution
Penicillin13
- Doctors also use clindamycin to treat infections in people with penicillin allergies. (medicalnewstoday.com)
- Intravenous high dose penicillin treatment, for five weeks, was started in combination with gentamicin, for the first 10 days. (cdc.gov)
- and the third study compared tetracycline enzyme-based antibiotic with intravenous penicillin G. (cochrane.org)
- We found no strong evidence that clindamycin alone is better than penicillin plus chloramphenicol for treating women with septic abortion. (cochrane.org)
- The use of tetracycline-enzyme antibiotic brought women's fever down faster than intravenous penicillin G. (cochrane.org)
- In addition, two women in the clindamycin group had pelvic abscess compared to one in the penicillin plus chloramphenicol group, although the difference was not significant. (cochrane.org)
- Tetracyline enzyme antibiotic appeared to be more effective than intravenous penicillin G in reducing the time to fever defervescence, but this evidence was provided by only one study at low risk of bias. (cochrane.org)
- Although the patient responded to intravenous penicillin and clindamycin, operative débridement was necessary because of clinical suspicion of early necrotizing fasciitis. (medscape.com)
- Fluoroquinolones, carbapenems and clindamycin are usually employed as alternatives to penicillin and are associated with greater risk of Clostridium difficile colitis, 6 which may increase mortality, hospital stays and overall costs. (bmj.com)
- The drug of choice is penicillin, or, for those allergic to penicillin, clindamycin or any other strep-specific antibiotic. (pregnancycrawler.com)
- Treatment involves aggressive fluid replacement, high doses of intravenous penicillin, high concentration of oxygen, and surgical debridement, and/or amputation. (oaepublish.com)
- The patient was resuscitated with intravenous fluids and oxygen and was given intravenous penicillin, gentamicin, and clindamycin. (oaepublish.com)
- Penicillin + clindamycin, though not for empiric therapy. (medscape.com)
Antibiotics10
- For initial antimicrobial treatment of infected wounds, beta-lactam antibiotics with anti-staphylococcal activity (cephalexin, dicloxacillin, ampicillin/sulbactam etc.) and clindamycin are recommended options. (cdc.gov)
- In severe cases or in hospitalized patients, intravenous antibiotics may be used to treat cellulitis. (everydayhealth.com)
- But, she adds, the decision may be made to prescribe antibiotics that cover both Gram-positive and Gram-negative bacteria, such as clindamycin (Cleocin HCI) or doxycycline (Vibramycin) . (everydayhealth.com)
- Treatment of necrotizing fasciitis involves early recognition and surgical debridement of necrotic tissue, combined with high-dose broad-spectrum intravenous antibiotics. (aafp.org)
- P. acnes is highly susceptible to a wide range of antibiotics, including beta-lactams, quinolones, clindamycin, and rifampin, although resistance to clindamycin is increasing. (uzh.ch)
- Cellulitis is a serious infection requiring intravenous antibiotics. (skinsight.com)
- If you are very sick or have other chronic illnesses that may complicate your recovery, you may need to be hospitalized to receive intravenous antibiotics. (skinsight.com)
- If a pregnant woman is found to be a GBS carrier, the infection can easily be treated with intravenous antibiotics. (infectiontalk.net)
- Even worse, someone may be discharged from the hospital on intravenous antibiotics - risking all the problems of parenteral access (clots, infection, pain, and myriad catheter malfunctions which only happen in the middle of the night/weekends) - when there are multiple oral options that will do the job just as well. (jwatch.org)
- Patients with CAP at risk of anaerobic infection should be initiated on antibiotics with anaerobic activity such as amoxicillin-clavulanate, clindamycin or moxifloxacin. (medicaldialogues.in)
Cleocin4
- CLEOCIN PHOSPHATE Sterile Solution in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. (nih.gov)
- CLEOCIN PHOSPHATE IV Solution in the GALAXY plastic container for intravenous use is composed of clindamycin phosphate equivalent to 300, 600 and 900 mg of clindamycin premixed with 5% dextrose as a sterile solution. (nih.gov)
- The mean C max of clindamycin for Clindesse was approximately 0.3%, 0.1%, and 7.6% of that observed after the administration of a 150 mg Cleocin® oral capsule (2.5 [micro ]g/mL), a 600 mg Cleocin® intravenous injection (10.9 [micro ]g/mL), and a single dose of 100 mg of Cleocin® Vaginal Cream (86.5 ng/mL), respectively. (theodora.com)
- Clindamycin (eg, Cleocin). (skinsight.com)
Injection5
- After intramuscular injection of clindamycin phosphate, peak concentrations of active clindamycin are reached within 3 hours in adults and 1 hour in pediatric patients. (nih.gov)
- And if you're receiving clindamycin as an intravenous (IV) infusion or injection into a muscle, you may have additional charges for its administration. (healthline.com)
- This product contains Clindamycin 150mg/ml in the form of INJECTION . (pharmfair.com)
- Linzac IV (Linezolid Intravenous Infusion 2mg/ml) Injection is administered intravenously (through a drip) or intramuscular injections (by an injection) under the guidance of a healthcare practitioner. (sriyalifescience.com)
- Linzac IV (Linezolid Intravenous Infusion 2mg/ml) Injection kills bacteria that are capable of causing severe diseases. (sriyalifescience.com)
Lincomycin6
- Clindamycin was first made in 1966 from lincomycin. (wikipedia.org)
- Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin. (nih.gov)
- Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. (theodora.com)
- Clindesse is contraindicated in individuals with a history of hypersensitivity to clindamycin, lincomycin, or any of the components of this vaginal cream. (theodora.com)
- Clindamycin is a semisynthetic lincosamide antibiotic that has largely replaced lincomycin due to an improved side effect profile. (pharmfair.com)
- 1. Usual care plus clindamycin (5 days) - Intravenous clindamycin (or lincomycin) 600 mg every 8 h for 5 days. (who.int)
Intramuscular3
- Comparative study of intravenous metronidazole and intramuscular dehydroemetine in amoebic liver abscess. (ajtmh.org)
- It is approved for INTRAVENOUS, INTRAMUSCULAR use. (pharmfair.com)
- The severe hypoglycaemia was resistant to general ward measures involving intramuscular glucagon and intravenous boluses of 50% dextrose. (technuc.com)
Vancomycin3
- Treatment options for these community MRSA infections include trimethoprim-sulfamethoxazole (oral) or vancomycin (intravenous). (cdc.gov)
- She was accepted to our medical center for failing of outpatient therapy and begun on intravenous vancomycin. (biomasswars.com)
- After 48 h of intravenous vancomycin there was a dramatic resolution of your skin lesions and she was turned to dental cotrimoxazole. (biomasswars.com)
Immunoglobulin5
- Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis. (bvsalud.org)
- We evaluated the effect of intravenous immunoglobulin ( IVIG ) on mortality in clindamycin -treated streptococcal toxic shock syndrome using a meta-analysis . (bvsalud.org)
- The debate for benefits of intravenous immunoglobulin continues to be waged in the recent literature. (medscape.com)
- On his initial admission, he was given intravenous immunoglobulin and steroids. (cdc.gov)
- During his second admission, new, moderate coronary dilation was noted, and he was treated with intravenous immunoglobulin and steroids. (cdc.gov)
Continuous intravenous infusion1
- Serum concentrations of clindamycin can be maintained above the in vitro minimum inhibitory concentrations for most indicated organisms by administration of clindamycin phosphate every 8 to 12 hours in adults and every 6 to 8 hours in pediatric patients, or by continuous intravenous infusion. (nih.gov)
Inhibits bacterial protein synthesis2
- Clindamycin inhibits bacterial protein synthesis at the level of the bacterial ribosome. (theodora.com)
- Clindamycin inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. (pharmfair.com)
Resistance to clindamycin3
- During a D-test, bacteria of the iMLSB phenotype demonstrate in vitro erythromycin-induced in vitro resistance to clindamycin. (wikipedia.org)
- Repeat cultures from the site grew MRSA with resistance to clindamycin. (biomasswars.com)
- The failures were due to inducible resistance to clindamycin (5 11 12 In a study by Hersh et al. (biomasswars.com)
Infusion1
- By the end of short-term intravenous infusion, peak serum concentrations of active clindamycin are reached. (nih.gov)
Weeks of intravenous2
- For non-MRSA disease, 4-6 weeks of intravenous (IV) therapy or therapy with drugs with high oral bioavailability is preferred. (medscape.com)
- Most authors suggest a course of 3 to 6 months of antibiotic treatment, including 2 to 6 weeks of intravenous treatment with a beta-lactam. (uzh.ch)
Commonly used intravenous1
- Stability of fluconazole in commonly used intravenous antibiotic solutions. (stabilis.org)
Vaginal4
- A doctor may prescribe clindamycin in the form of a transvaginal suppository to treat bacterial vaginal infections. (medicalnewstoday.com)
- Alternatively, they may prescribe a clindamycin lotion for vaginal infections. (medicalnewstoday.com)
- Does not comply with the pH test of the USP monograph for clindamycin phosphate vaginal cream. (theodora.com)
- Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosomal subunits of the bacteria. (pharmfair.com)
Contains clindamycin phosphate1
- Clindesse is a semi-solid, white cream, which contains clindamycin phosphate, USP, at a concentration equivalent to 20 mg clindamycin base per gram. (theodora.com)
Infections12
- A doctor may recommend clindamycin for certain respiratory infections, lung infections, blood poisoning, and more. (medicalnewstoday.com)
- Doctors prescribe clindamycin to treat bacterial infections in certain situations. (medicalnewstoday.com)
- Topical clindamycin is a common treatment option for acne and bacterial infections in the vagina. (medicalnewstoday.com)
- Doctors use clindamycin to treat a variety of bacterial infections. (medicalnewstoday.com)
- Before having surgery, some people receive clindamycin to prevent surgical site infections. (medicalnewstoday.com)
- Clindamycin is an antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. (wikipedia.org)
- Clindamycin is used primarily to treat anaerobic infections caused by susceptible anaerobic bacteria, including dental infections, and infections of the respiratory tract, skin, and soft tissue, and peritonitis. (wikipedia.org)
- In people with hypersensitivity to penicillins, clindamycin may be used to treat infections caused by susceptible aerobic bacteria, as well. (wikipedia.org)
- Clindamycin is a generic prescription drug that's used to treat certain bacterial infections. (healthline.com)
- Reports since 2000 document B. anthracis soft-tissue infections in intravenous heroin users in northern Europe. (unboundmedicine.com)
- Clindamycin is an attractive agent for empirical therapy for suspected infections because of its excellent pharmacokinetic and pharmacodynamic properties (1). (biomasswars.com)
- Clinical failures of clindamycin therapy for treatment of MRSA infections have been documented for strains that were clindamycin sensitive but erythromycin resistant. (biomasswars.com)
Fluids2
- Intravenous fluids are required if the patient is dehydrated because of fever and difficulty swallowing. (medscape.com)
- Treatment comprises bed rest, intravenous fluids, and symptomatic management with antipyretics and analgesics. (medscape.com)
Topical8
- Topical application of clindamycin phosphate can be used to treat mild to moderate acne. (wikipedia.org)
- For the treatment of acne, in the long term, the combined use of topical clindamycin and benzoyl peroxide was similar to salicylic acid plus benzoyl peroxide. (wikipedia.org)
- Topical clindamycin plus topical benzoyl peroxide is more effective than topical clindamycin alone. (wikipedia.org)
- Does clindamycin topical gel cost more than its 300-mg oral capsule? (healthline.com)
- To learn more about how the cost of clindamycin topical gel compares with the cost of the 300-mg capsules, talk with your doctor or pharmacist. (healthline.com)
- Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of orally and parenterally administered clindamycin, as well as with topical (dermal) formulations of clindamycin. (theodora.com)
- Topical clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles. (pharmfair.com)
- Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. (pharmfair.com)
Meropenem2
- Evaluation of the efficacy and safety of intravenous ciprofloxacin versus meropenem in the treatment of postoperative infection. (druglib.com)
- Two sets of blood cultures were taken and she was loaded with intravenous meropenem and clindamycin. (ijmsweb.com)
Metronidazole4
- Intravenous metronidazole in amoebic liver abscess. (ajtmh.org)
- Treatment with metronidazole by the intravenous route. (ajtmh.org)
- Intravenous metronidazole in the treatment of ruptured amebic liver abscess. (ajtmh.org)
- Treatment of an amebic liver abscess with intravenous metronidazole. (ajtmh.org)
Prescribe clindamycin2
- A dermatologist may prescribe clindamycin in the form of a gel, solution, or lotion to treat acne. (medicalnewstoday.com)
- This skepticism may lead to reluctance to prescribe clindamycin for patients who may otherwise benefit from its unique properties. (biomasswars.com)
Bacteria5
- Depending on the type of infection and the dosage of clindamycin, the drug can either kill or stop the growth of bacteria . (medicalnewstoday.com)
- Most aerobic Gram-negative bacteria (such as Pseudomonas, Legionella, Haemophilus influenzae and Moraxella) are resistant to clindamycin, as are the facultative anaerobic Enterobacteriaceae. (wikipedia.org)
- 64 μg/ml When testing a gram-positive culture for sensitivity to clindamycin, it is common to perform a "D-test" to determine if there is a sub-population of bacteria present with the phenotype known as iMLSB. (wikipedia.org)
- To perform a D-test, an agar plate is inoculated with the bacteria in question and two drug-impregnated disks (one with erythromycin, one with clindamycin) are placed 15-20 mm apart on the plate. (wikipedia.org)
- Flesh-Eating Bacteria Treatment · Intravenous antibiotic therapy. (bye.fyi)
Plus clindamycin1
- artesunate as the fi rst-line treatment in sunate monotherapy (n = 1), or IV arte- cdc.gov/malaria/features/artesunate_ adults with severe malaria in such areas sunate plus clindamycin (n = 1). (cdc.gov)
Form of clindamycin2
- This is because the form of clindamycin the doctor prescribes depends on the kind of infection the person has. (medicalnewstoday.com)
- Your cost may depend on your treatment plan, your insurance coverage, the form of clindamycin you're prescribed, and the pharmacy you use. (healthline.com)
Antibiotic treatment1
- All patients received intravenous antibiotic treatment and recovered. (lu.se)
Linezolid1
- Use linezolid or add clindamycin if suspicion for TSS. (medscape.com)
Gentamicin1
- A typical empiric antibiotic regimen includes clindamycin 900 mg IV every 8 hours plus gentamicin 5 mg/kg IV once a day, with or without ampicillin 2 g IV every 4 hours. (msdmanuals.com)
Active clindamycin3
- Biologically inactive clindamycin phosphate is converted to active clindamycin. (nih.gov)
- however, the average serum elimination half-life of active clindamycin is about 3 hours in adults and 2½ hours in pediatric patients. (nih.gov)
- Although clindamycin phosphate is inactive in vitro , rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin. (theodora.com)
Treatment8
- Dentists also use clindamycin as a preventive treatment for endocarditis, which is an infection of the heart's lining that can occur after a dental procedure in people who are at risk. (medicalnewstoday.com)
- Only one study reported harm experienced by women: two women given clindamycin had treatment failure, and one woman had an adverse drug reaction. (cochrane.org)
- This means your insurer and your doctor will discuss clindamycin in regard to your treatment. (healthline.com)
- If clindamycin requires prior authorization and you don't receive it before you start treatment, you could pay the full cost of the drug. (healthline.com)
- Treatment for tendinitis was started in the form of diclofenac 50 mg × 3 orally, with intravenous clindamycin 300 mg × 4 to cover infection. (tidsskriftet.no)
- Treatment during labor usually consists of intravenous antibiotic therapy. (pregnancycrawler.com)
- Treatment of septic abortion includes intravenous broad-spectrum antibiotic therapy, which should be initiated immediately. (msdmanuals.com)
- Trimethoprim-sulfamethoxazole (TMP-SMX) has been shown to be as effective as intravenous pentamidine and more effective than other alternative treatment regimens. (medscape.com)
Isolates5
- Patient-derived isolates of Plasmodium falciparum from the Peruvian Amazon have been reported to be resistant to clindamycin as evidenced by in vitro drug susceptibility testing. (wikipedia.org)
- Clindamycin is also a potential option, but not all isolates are susceptible. (cdc.gov)
- Since 2004 CLSI offers recommended that laboratories record D test-positive isolates as resistant to clindamycin (8). (biomasswars.com)
- Clindamycin level of resistance is common amongst isolates as well as the prices of level of resistance vary by area. (biomasswars.com)
- In 2008 the Louisiana Condition Antibiotic Sensitivity Monitoring Program reported that 27% of MRSA isolates had been resistant to clindamycin (7). (biomasswars.com)
Cefazolin1
- 1. Cefazolin - Intravenous cefazolin 2 g every 6 or 8 h. (who.int)
Rifampin1
- You can pretty much guarantee that if a patient needs intravenous rifampin, he/she also needs an ID consult. (jwatch.org)
Orally1
- Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally. (theodora.com)
Doxycycline1
- Combination of doxycycline and clindamycin has not been recommended. (vin.com)
MRSA1
- Testing of the prior MRSA isolate verified the current presence of inducible clindamycin level of resistance. (biomasswars.com)
Oral2
- More recent data have suggested that oral therapy is equivalent to IV therapy (see Intravenous vs Oral Antimicrobial Agents, below), but this has yet to be incorporated into guidelines. (medscape.com)
- Her maintainence oral steroid was switched to intravenous hydrocortisone 50?mg four times a day. (technuc.com)
Vitro1
- In vitro studies in human liver and intestinal microsomes indicated that clindamycin is predominantly metabolized by Cytochrome P450 3A4 (CYP3A4), with minor contribution from CYP3A5, to form clindamycin sulfoxide and a minor metabolite, N-desmethylclindamycin. (nih.gov)
Therapy5
- Samples for blood and synovial fluid cultures were obtained and anti-microbial therapy with intravenous cefuroxime was started. (cdc.gov)
- Eradication antibiotic therapy with clindamycin and rifampicin was given to the carrier. (lu.se)
- Fluid therapy and intravenous ranitidine was administered until the dog was able to drink and eat. (vin.com)
- Bacterial strains with an inducible genotype possess a high prospect of spontaneous mutation to a constitutive Zanamivir genotype during clindamycin therapy (3). (biomasswars.com)
- Co-trimoxazole was switched to second-line PCP Cinnamyl alcohol manufacture therapy, which consisted of clindamycin and primaquine. (technuc.com)
Equivalent1
- Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each mL. (nih.gov)
Erythromycin1
- Despite the apparent susceptibility to clindamycin in the absence of erythromycin, a positive D-test precludes therapeutic use of clindamycin. (wikipedia.org)
Drug7
- Clindamycin is an antibiotic drug. (medicalnewstoday.com)
- Some people can also take clindamycin for uses that the Food and Drug Administration (FDA) has not formally approved. (medicalnewstoday.com)
- A notable exception is Capnocytophaga canimorsus, for which clindamycin is a first-line drug of choice. (wikipedia.org)
- Is clindamycin available as a brand-name drug? (healthline.com)
- Clindamycin is a generic drug. (healthline.com)
- If you've been prescribed clindamycin and you're interested in a brand-name drug instead, talk with your doctor. (healthline.com)
- Intravenous drug abuse. (skinsight.com)
Contrast1
- A retropharyngeal abscess was suspected, and the patient was referred for a cervical CT with intravenous contrast. (tidsskriftet.no)
Concentrations1
- No significant concentrations of clindamycin are attained in the cerebrospinal fluid even in the presence of inflamed meninges. (nih.gov)
Malaria2
- Sometimes, for example, doctors use clindamycin to treat anthrax and malaria. (medicalnewstoday.com)
- One patient was a cline or clindamycin to all but 1 of our ing malaria parasites only a few hours pregnant (third trimester) immigrant. (cdc.gov)
Solution1
- Does Clindamycin PHOSPHATE-D5W Solution, Intravenous Piggyback Interact with other Medications? (webmd.com)