Intravenous administration or intravenous administration. Medical search. Frequent questions

When access to the lever was blocked and the infusion pump was inactivated at the end of self-administration sessions, the animals became agitated and the electrochemical signal increased and remained elevated for 20-40 min before gradually declining toward the original baseline. (jneurosci.org)
High doses of ascorbic acid administered by intravenous infusion have been shown to increase the absorption of iron. (wikipedia.org)
In 1976, Pauling and Cameron co-authored a study whereby a group of 100 terminal cancer patients underwent supplementary ascorbic acid therapy (10g/day by intravenous infusion and oral thereafter) and the control group of 1,000 patients did not. (wikipedia.org)
Average plasma concentrations of ceftriaxone following a single 30-minute intravenous (IV) infusion of a 0.5, 1 or 2 g dose and intramuscular (IM) administration of a single 0.5 (250 mg/mL or 350 mg/mL concentrations) or 1 g dose in healthy subjects are presented in Table 1. (nih.gov)
The Day hospital (infusion suite) facilities at a reference hospital were considered for IV administrations and the first six SC injections . (bvsalud.org)
Besides the potential benefits of convenient administration and improving work-life balance , as suggested by the expert panel, natalizumab SC was associated with cost savings for the healthcare system by avoiding drug preparation , reducing administration time , and freeing up infusion suite capacity. (bvsalud.org)

Data relevant to the use of tecovirimat, brincidofovir, cidofovir, trifluridine ophthalmic solution, and vaccinia immune globulin intravenous were reviewed. (cdc.gov)
MCMs developed for smallpox preparedness or shown to be effective against other OPXVs (i.e., tecovirimat, brincidofovir, cidofovir, trifluridine ophthalmic solution, and vaccinia immune globulin intravenous [VIGIV]) have been used to treat severe mpox. (cdc.gov)
vaccinia immune globulin intravenous, axicabtagene ciloleucel. (medscape.com)
vaccinia immune globulin intravenous, brexucabtagene autoleucel. (medscape.com)
vaccinia immune globulin intravenous, idecabtagene vicleucel. (medscape.com)
vaccinia immune globulin intravenous, lisocabtagene maraleucel. (medscape.com)

In trained animals, cocaine self-administration was accompanied by a tonic elevation of DA-associated signals and by phasic fluctuations time-locked to each cocaine injection. (jneurosci.org)
Vibramycin ( doxycycline hyclate for injection) Intravenous is an antibacterial drug synthetically derived from oxytetracycline, and is available as Vibramycin Hyclate (doxycycline hydrochloride hemiethanolate hemihydrate). (rxlist.com)
Ceftriaxone for injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. (nih.gov)
An increase in heart rate of about 35 beats/minute (which is usually not noticed by the recipient) within 3-5 minutes of an I.V. dose, and a maximal increase in heart rate of about 35-45 beats/minute with I.M. or autoinjector administration, respectively, within about 35-45 minutes (the longer being with I.M. injection). (cdc.gov)
For intravenous (IV) injection over a period of 2 minutes, administer the appropriate volume of the reconstituted CUBICIN (concentration of 50 mg/mL). (globalrph.com)
For intravenous use after reconstitution with sterile water for injection and further dilution with 0.9% sodium chloride injection. (who.int)

The preferred route of administration for an injected therapeutic agent is subcutaneous (SC), but SC injections are generally limited to no more than 1-2 mL in volume, representing a major challenge, especially for large protein biologics. (pharmtech.com)
During SC administration, a needle is inserted through the epidermal and dermal layers of the skin and into the fatty subcutaneous tissue. (pharmtech.com)
Cost-Analysis of Subcutaneous vs Intravenous Administration of Natalizumab Based on Patient Care Pathway in Multiple Sclerosis in Spain. (bvsalud.org)

The pharmacokinetics of lotilaner were investigated after intravenous or oral administration and under fed or fasted conditions in cats. (biomedcentral.com)
The pharmacokinetics of lotilaner were determined in dogs after intravenous and oral administration and under different feeding regimens [ 14 ]. (biomedcentral.com)
Single Dose Pharmacokinetics of Cefepime after Intravenous and Intramu" by KALPESH PATANI, URVESH PATEL et al. (tubitak.gov.tr)
Pharmacokinetics of cefepime was determined following single dose intravenous (IV) and intramuscular (IM) administration at the rate of 10 mg/kg body weight in a crossover design with an interval of 21 days between IV and IM injections. (tubitak.gov.tr)
Comparative pharmacokinetics of metronidazole and tinidazole as influenced by administration route. (ajtmh.org)
The present study was designed to determine and compare the plasma disposition and pharmacokinetics of penicillin G sodium following intravenous (i.v.) administration to horses, ponies and donkeys. (herts.ac.uk)

These patients need to be hospitalized for frequent monitoring of their blood pressure, administration of intravenous fluids, and other supportive therapy. (cdc.gov)

In in vitro studies, the primary mechanism of high dosage intravenous ascorbic acid can be related to ascorbic acid's pro-oxidant activity, whereby hydrogen peroxide is formed. (wikipedia.org)
Following the oral administration at a dosage of 6 mg/kg, under fed or fasted conditions, or intravenous administration of 3 mg/kg, blood samples were collected up to 35 days after treatment. (biomedcentral.com)
RYBREVANT is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test [see Dosage and Administration (2.1) ] , whose disease has progressed on or after platinum-based chemotherapy. (drugs.com)
Since the calcium folinate rescue dosage regimen depends heavily on the posology and method of the intermediate- or high-dose methotrexate administration, the methotrexate protocol will dictate the dosage regimen of calcium folinate rescue. (janusinfo.se)

Variability in the concentrations of intravenous drug infusions prepared in a critical care unit. (ahrq.gov)
Of the observed infusions, 699 (60%) had one or more errors associated with their administration. (bmj.com)
Can iron infusions rechallenge occur safely in an individual with a history of reactions due to intravenous (IV) iron? (kjfm.or.kr)

Intravenous Ascorbic Acid (also known as vitamin C or L-ascorbic acid), is a process that delivers soluble ascorbic acid directly into the bloodstream. (wikipedia.org)
The use of intravenous ascorbic acid as a proposed cancer treatment or co-treatment has been a controversial topic since the emergence of misleading data in the 1970s. (wikipedia.org)
In individuals with hemochromatosis (a genetic disorder where the body takes up and stores too much iron), intravenous ascorbic acid is contraindicated as high dosages of ascorbic acid may result in iron overloading and therefore, lead to life-threatening complications such as heart disease, diabetes, or tissue damage. (wikipedia.org)
High dosages of ascorbic acid (such as those used in intravenous therapy) have been reported to cause some intestinal discomfort, diarrhoea, as well as increased gas and urination. (wikipedia.org)
Although many in vitro studies have studied hydrogen peroxide generation by ascorbic acid, the pharmacological mechanism of intravenous ascorbic acid in vivo is still unclear. (wikipedia.org)
Although the pharmacology of ascorbic acid had been studied since its discovery in the 1930s, the method of administration and its medicinal potential to human patients was not investigated until the 1940s. (wikipedia.org)
In 1949, American physician, Frederick Klenner, published his scientific report, "The Treatment of Poliomyelitis and Other Virus Diseases with ascorbic acid", which detailed the use of intravenous ascorbic acid to treat polio in children. (wikipedia.org)
Klenner's research pioneered future studies investigating the medicinal role of intravenous ascorbic acid. (wikipedia.org)
Nobel Prize winner and biochemist, Linus Pauling, was pivotal in the re-emergence of intravenous ascorbic acid research. (wikipedia.org)
Following these findings, Pauling became a strong advocate for vitamin megadosing and continued to investigate the medicinal potential of intravenous ascorbic acid across a range of illnesses, including: HIV transmission, the common cold, atherosclerosis, and angina pectoris. (wikipedia.org)

Following oral administration in fed cats, lotilaner was readily absorbed and peak blood concentrations reached within four hours. (biomedcentral.com)
Following oral administration to fed dogs, lotilaner displayed a terminal half-life (T 1/2z ) of 30.7 days and maximum blood concentrations were reached within two hours. (biomedcentral.com)
Ceftriaxone was completely absorbed following IM administration with mean maximum plasma concentrations occurring between 2 and 3 hours post-dose. (nih.gov)
Serum concentrations of caffeine should be monitored and dose administration of caffeine citrate should be adjusted to avoid toxicity in this population. (drugs.com)
or = 0.6 micrograms ml-1) was measured in caecal liquor following i.v. administration, however the risk of development of antimicrobial-associated colitis would be high following oral administration of penicillin G since high concentrations of drug (4.96-157.12 micrograms ml-1) were measured in caecal liquor. (herts.ac.uk)

A comparison of error rates between intravenous push methods: a prospective, multisite, observational study. (ahrq.gov)
Each monograph contains stability data, administration guidelines, and methods of preparation. (globalrph.com)
The mood effects but not the physiological effects of intravenous caffeine were similar to those previously observed with cocaine in studies using similar methods and subjects. (erowid.org)

Therapeutic agents can be introduced into the body by several routes of administration with each having specific advantages and disadvantages (see Table I). For many drugs, including biologics and anticancer agents, the traditional route of administration is intravenous (IV). (pharmtech.com)
Further studies on how to improve the therapeutic efficacy of intravenous thrombolysis are always important. (frontiersin.org)

Intravenous fentanyl in 0.9% sodium chloride solution from a 250-mL (10 mcg/mL) bag prepared at compounding pharmacy A. ‡Strain A is the outbreak strain that was indistinguishable by PFGE from the fentanyl isolates. (cdc.gov)

A review of best practices for intravenous push medication administration. (ahrq.gov)
Mistakes in intravenous push medication administration can cause patient harm . (ahrq.gov)
Introduction Intravenous medication errors persist despite the use of smart pumps. (bmj.com)
This suggests the need for a standardised methodology for measuring errors and highlights the importance of identifying issues around smart pump medication administration in order to improve patient safety. (bmj.com)
Objectives We conducted a multisite study to investigate the types and frequency of intravenous medication errors associated with smart pumps in the USA. (bmj.com)
Results A total of 478 patients and 1164 medication administrations were assessed. (bmj.com)
The results of this study will be useful in developing interventions to eliminate errors in the intravenous medication administration process. (bmj.com)
Other available information technologies that may prove effective for inpatients include computerized medication administration records, robots, automated pharmacy systems, bar coding, "smart" intravenous devices, and computerized discharge prescriptions and instructions. (bmj.com)

Therefore, we planned a clinical trial with intravenous vitamin C administration. (nih.gov)
These patients may sometimes have limited vascular access, so availability of compatibility charts for intravenous Y-site administration may help daily clinical practice. (nursingcenter.com)

Intravenous smart pump drug library compliance: a descriptive study of 44 hospitals. (ahrq.gov)
After approximately 18 months of MDMA self-administration, drug exposure was halted and after at least 2 months drug abstinence, animals were scanned using positron emission tomography (PET) with the vesicular monoamine transporter (VMAT) ligand dihydrotetrabenazine (DTBZ). (erowid.org)
Pediatric patients admitted to intensive care units are likely candidates for intravenous drug administration. (nursingcenter.com)
A 2-dimensional table with the 47 intravenous drugs more commonly administered in the authors' pediatric intensive care unit was drawn up based on a review of 4 databases routinely used for checking drug compatibilities. (nursingcenter.com)
The serum drug concentration-time profile was characteristic of a 2- and 1-compartment open model following IV and IM administration, respectively. (tubitak.gov.tr)
Following IM administration, the drug was rapidly absorbed (t_{1/2ka}: 0.16 ± 0.01 h) and slowly eliminated (t_{1/2\beta }: 4.89 ± 0.24 h) from body. (tubitak.gov.tr)
However, widespread off-label use of intravenous subanesthetic-dose ketamine for treatment-resistant depression has raised concerns about side effects, especially given its history as a drug of abuse. (nih.gov)
We did not see any serious, drug-related adverse events or increased ketamine cravings with a single-administration. (nih.gov)
Meanwhile, the U.S. Food and Drug Administration earlier this year approved an intranasal form of ketamine called esketamine, which can be administered to adults with treatment-resistant depression in a certified doctor's office or clinic. (nih.gov)
Flutemetamol was first approved for use in the US by the Food and Drug Administration (FDA) in 2013 for intravenous use. (wikipedia.org)
Considering the patient care pathway and according to natalizumab experience (IV) or estimation (SC), a national expert panel involving neurologists , pharmacists , and nurses provided information/data regarding resource consumption for drug and patient preparation, administration , and documentation . (bvsalud.org)
The present study was conducted to examine the self-reported (i.e., subjective) and physiological effects of intravenous caffeine in 10 subjects with histories of stimulant drug abuse. (erowid.org)
The manufacturers, with numerous efforts and experiments reported to Food and drug administration that they were not able to satisfy the demand for drugs. (medgadget.com)

1989) others disagree, having noted prompt resolution of CNS symptoms after its administration. (cdc.gov)

Thus, the effects of cocaine on DA-associated signals in nucleus accumbens (1) changed dramatically during the development of the self-administration habit and (2) depended on environmental and behavioral as well as pharmacological factors. (jneurosci.org)

CONCLUSIONS AND RELEVANCE: Two predictors of poor outcomes for STEC-infected children were identified: (1) the lack of intravenous fluid administration prior to establishment of HUS and (2) a higher hematocrit value at presentation. (mcmaster.ca)

Endocarditis due to enterococcal strains usually respond to intravenous therapy. (nih.gov)
dysentery) usually respond to oral or intravenous therapy. (nih.gov)
Over the course of the 1970s, Pauling would begin a long-term collaboration with fellow physician, Ewan Cameron, on the medical potential of intravenous ascorbate acid as cancer therapy in terminally ill patients. (wikipedia.org)
Intravenous (IV) iron therapy is performed in community practices and hospitals with modern formulations when oral administration becomes impractical. (kjfm.or.kr)
Re-administration of IV iron therapy in patients with a previous adverse reaction is plausible, with benefit and risk stratification. (kjfm.or.kr)
[ 5 ] . A 2015 update of the American Heart Association/American Stroke Association guidelines for the early management of patients with acute ischemic stroke recommends that patients eligible for intravenous t-PA should receive intravenous t-PA even if endovascular treatments are being considered and that patients should receive endovascular therapy with a stent retriever if they meet criteria. (medscape.com)
Although penicillin G was absorbed rapidly following nasogastric administration, the systemic availability was low (0.12-0.34%), therefore oral administration would be unsuitable for systemic antimicrobial therapy in the equine. (herts.ac.uk)
This study aimed to assess the implications of the new SC formulation, and to compare the annual treatment costs of SC versus intravenous (IV) natalizumab therapy from both the Spanish healthcare system (direct health cost ) and the patient (indirect cost ) perspectives. (bvsalud.org)

After oral administration of 10 mg caffeine base/kg to preterm neonates, the peak plasma level (C max ) for caffeine ranged from 6 to 10 mg/L and the mean time to reach peak concentration (T max ) ranged from 30 minutes to 2 hours. (drugs.com)
caffeine levels are approximately 25% of theophylline levels after theophylline administration and approximately 3 to 8% of caffeine administered would be expected to convert to theophylline. (drugs.com)
Intravenous caffeine administration may provide a useful model system for investigating factors relevant to the use and abuse of stimulant drugs. (erowid.org)

Conclusion We identified a high rate of error in the administration of intravenous medications despite the use of smart pumps. (bmj.com)

The aim of this meta-analysis was to determine the role of an aggressive intravenous hydration protocol of Lactated Ringer's solution in patients with mild acute pancreatitis (MAP). (frontiersin.org)
Administration of glucose in hypoglycemia produces profound and prompt improvement, while insulin should be started for patients with stroke and hyperglycemia. (medscape.com)
Intravenous thrombolysis (IVT) is a standard procedure for the treatment of patients with acute ischemic stroke (AIS). (frontiersin.org)
Intravenous thrombolysis or/and intraarterial thrombectomy to reopen occluded cerebral arteries is a standard treatment procedure for AIS patients. (frontiersin.org)
In smaller hospitals, especially in rural areas, intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) remains the mainstay for AIS patients ( 3 , 4 ). (frontiersin.org)
Early neurological deterioration (END) within the first 24 h after intravenous thrombolysis is a major problem leading to poor outcomes in AIS patients ( 5 ). (frontiersin.org)
Productivity time associated with travel (56 min to reference hospital , 24 min to regional hospital ) and waiting time pre- and post- treatment (SC 15 min, IV 25 min) were assessed for patients and caregivers (accompanying 20% of SC and 35% of IV administrations). (bvsalud.org)
Calcium folinate rescue has to be performed by parenteral administration in patients with malabsorption syndromes or other gastrointestinal disorders where enteral absorption is not assured. (janusinfo.se)

Large proteins are typically not suited for oral administration, as such drugs would be degraded in the digestive tract and poorly absorbed. (pharmtech.com)

We evaluated the effect of intravenous vitamin C on fatigue in office workers. (nih.gov)
Thus, intravenous vitamin C reduced fatigue at two hours, and the effect persisted for one day. (nih.gov)
High dose intravenous vitamin C proved to be safe and effective against fatigue in this study. (nih.gov)
The "Marik protocol", or "HAT" protocol, as devised by Paul E. Marik, proposed a combination of intravenous vitamin C, hydrocortisone, and thiamine as a treatment for preventing sepsis for people in intensive care. (wikipedia.org)

The reinforcing effects of cocaine were not altered by chronic MDMA self-administration, nor was the VMAT binding potential as assessed by PET. (erowid.org)

The elimination of penicillin G into the gastrointestinal tract following i.v. administration and the absorption of penicillin G from the gastrointestinal tract following oral administration were studied in two ponies with cannulated caecal fistulas. (herts.ac.uk)

Intravenous Ghrelin Administration Increases Alcohol Craving in Alcoho" by Lorenzo Leggio, William H. Zywiak et al. (unl.edu)
Here, we were the first to test the hypothesis that intravenous administration of exogenous ghrelin acutely increases alcohol craving. (unl.edu)

Twenty-six adult cats were enrolled in a pharmacokinetic study evaluating either intravenous or oral administration of lotilaner. (biomedcentral.com)

In the rat, the liver represents a major site of phosphorothioate oligodeoxynucleotide deposition after i.v. administration. (aspetjournals.org)
Our results suggest that although pharmacokinetic parameters vary as a function of hepatic cell type, significant intracellular delivery can be readily achieved in the liver after systemic administration. (aspetjournals.org)
Intravenous metronidazole in amoebic liver abscess. (ajtmh.org)
Comparative study of intravenous metronidazole and intramuscular dehydroemetine in amoebic liver abscess. (ajtmh.org)
Intravenous metronidazole in the treatment of ruptured amebic liver abscess. (ajtmh.org)
Treatment of an amebic liver abscess with intravenous metronidazole. (ajtmh.org)

To overcome the limitations associated with side effects and intravenous delivery, ongoing research efforts seek to develop a more practical rapid-acting antidepressant that works in the brain similarly to ketamine. (nih.gov)

Calcium folinate can be administered either by the intravenous route at a dose of 20 mg/m2 for 5 to 10 minutes every 6 hours for a total daily dose of 80 mg/m2 or by oral route with four doses of 20 mg/m2 administered at equal time intervals. (janusinfo.se)

To assess further the role of insulin in the abnormal alpha-cell dysfunction found in human diabetes mellitus, the effects of acute insulin withdrawal and administration on plasma glucagon responses to intravenous arginine were studied in eight insulin-dependent diabetic subjects. (diabetesjournals.org)

During administration of metandienon the mean plasma testosterone level fell 69%, from 29.4 +/- 11.6 nmol/1 to 9.1 +/- 7.5 nmol/1. (nih.gov)
Our results show that administration of an anabolic steroid causes a pronounced lowering of plasma levels of testosterone, LH and FSH but causes no gross alteration in the response of LH secretion to stimulation by LRH. (nih.gov)
Early administration of plasma and platelets probably helps minimize the dilutional and consumptive coagulopathy that accompanies major hemorrhage. (merckmanuals.com)

Most side effects peaked within an hour of ketamine administration and were gone within two hours. (nih.gov)

Because LH and FSH levels were low after administration of the steroid the maximum stimulation values after LRH administration were also lower than pre-treatment values although the mean increments did not differ significantly before and after administration of the anabolic steroid. (nih.gov)
Administration of LRH after the treatment period had no effect on FSH secretion in two subjects and no effect on LH secretion in one. (nih.gov)
Treatment with metronidazole by the intravenous route. (ajtmh.org)
In addition to calcium folinate administration, measures to ensure the prompt excretion of methotrexate (maintenance of high urine output and alkalinisation of urine) are integral parts of the calcium folinate rescue treatment. (janusinfo.se)

The reason for the biphasic response pattern of FSH to LRH administration in most subjects is not known. (nih.gov)

refer to the applied intermediate or high dose methotrexate protocol for posology and method of administration of calcium folinate. (janusinfo.se)

Overdosage (possibly occurring with trimetrexate doses above 90 mg/m2 without concomitant administration of calcium folinate): after stopping trimetrexate, calcium folinate 40 mg/m2 IV every 6 hours for 3 days. (janusinfo.se)

Fantegrossi WE, Woolverton WL, Kilbourn M, Sherman P, Yuan J, Hatzidimitriou G, Ricaurte GA, Woods JH, Winger G. "Behavioral and Neurochemical Consequences of Long-Term Intravenous Self-Administration of MDMA and Its Enantiomers by Rhesus Monkeys" Neuropsychopharmacology . (erowid.org)

Ms. Chapman is to be admitted again to Lutheran Medical Center on 4/7/98 for the administration of an intravenous pic line. (angelfire.com)

Anatomy20

Organisms23

Diseases14

Chemicals and Drugs108

Analytical, Diagnostic and Therapeutic Techniques and Equipment64

Psychiatry and Psychology3

Phenomena and Processes35

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture4

Health Care9

Infusion6

Vaccinia immune globulin intravenous6

Injection6

Subcutaneous3

Pharmacokinetics6

Fluids1

Dosage4

Infusions3

Ascorbic Acid10

Concentrations5

Methods3

Therapeutic2

Sodium1

Medication8

Clinical2

Drug13

19891

Pharmacological1

Fluid administration1

Therapy8

Caffeine3

Conclusion1

Patients8

Drugs1

Vitamin4

Cocaine1

Absorption1

Increases2

Adult1

Liver6

Delivery1

Oral1

Withdrawal1

Plasma3

Effects1

Treatment4

Subjects1

High1

Doses1

MDMA1

Medical1