We investigated whether catheter-based, intramyocardial transplantation of autologous endothelial progenitor cells can enhance neovascularization in myocardial ischemia. (stemyoon.org)
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. (sciendo.com)
Weeks after transplantation4
In the swine study, ischemic area by NOGA mapping, Rentrop grade angiographic collateral development, and echocardiographic left ventricular ejection fraction improved significantly 4 weeks after transplantation of NA/CD31+ MNCs but not after injection of NA/CD31- MNCs or PBS. (stemyoon.org)
Capillary density in ischemic myocardium 4 weeks after transplantation was significantly greater in the NA/CD31+ MNC group than the control groups. (stemyoon.org)
Constructs with vessel anastomoses survived and maintained their vascular structure up to two weeks after transplantation. (encyclopedia.pub)
Skeletal myoblast2
However, according to serious complications reported for skeletal myoblast cells transplantation, giving ethical approval for using this cell type in human research requires strict commitment to precise methods (such as inclusion criteria, patient follow-up methods, and prophylactic treatments). (ac.ir)
In addition, phase II clinical trials have been performed by Japanese scientists to evaluate the efficacy and safety of autologous skeletal myoblast sheet transplantation in patients with advanced heart failure. (encyclopedia.pub)
Progenitor1
Progenitor cell therapy describes the use of multipotent cells of various cell lineages (autologous or allogeneic) for tissue repair and/or regeneration. (southcarolinablues.com)
Mesenchymal4
In experimental studies, mesenchymal stem cell (MSC) transplantation in acute myocardial infarction (AMI) models has been associated with enhanced neovascularization and myogenesis. (drcalapai.com)
In 2011, researchers evaluated the safety and effectiveness of intracardiac injection of autologous mesenchymal stem cells cultured in vitro in patients with stable coronary artery disease and refractory angina. (medicaltrend.org)
Another laboratory conducted a phase II trial in which a total of 60 patients with chronic ischemic heart failure received intramyocardial injection of mesenchymal stem cells or a placebo at a 2:1 ratio. (medicaltrend.org)
Vineberg later created an intramyocardial tunnel prior to LIMA implantation, and patency of these grafts was documented two decades later. (medscape.com)
Ruengsakulrach P, Visudharom K, Chaothawee L, Belkin M. Safety and Efficacy of Intramyocardial Implantation of Peripheral Blood Stem Cell for Cardiomyopathy. (tci-thaijo.org)
Allogeneic2
Also, the potential use of cell-sheets that contain allogeneic hiPSC-CMs for clinical transplantation is under investigation [ 11 ] . (encyclopedia.pub)
Seven eighty six patients undergoing allogeneic (n=550) or autologous (n=236) BMT were evaluated by physical examination, history, rest and exercise ECG, chest x-ray, two-dimensional echocardiography, and radionuclide ventriculography (RNV) before BMT, and monitored for 5 months thereafter. (slideshare.net)
Organ transplantation2
In clinical practice, these involve the life-long immunosuppression of the organ transplantation patients, the creation of the supporting environment for engineered tissues in the mended organ, the unsolved issues of cell survival and differentiation of the cell-based therapy, and the selection and development of vectors for gene therapy. (biomedcentral.com)
This prompted Vineberg to implant the left internal mammary artery (LIMA) directly onto the myocardium with the purpose of developing collaterals between the LIMA and the intramyocardial arterioles. (medscape.com)
Autologous transplantation of 10(7) NA/CD31+ MNCs, 10(7) NA/CD31- MNCs, or PBS was performed with a NOGA mapping injection catheter to target ischemic myocardium. (stemyoon.org)
Injection5
Therefore, the present study evaluates the safety and feasibility of intramyocardial MSC injection in nine patients, shortly after AMI during short-term and 5-year follow-up. (drcalapai.com)
The present safety and feasibility study suggest that intramyocardial injection of MSC in patients shortly after AMI is feasible and safe up to 5-year follow-up. (drcalapai.com)
To determine the safety and efficacy of intramyocardial autologous blood stem cell injection for cardiomyopathy. (tci-thaijo.org)
Between May 2005 and February 2010, 126 consecutive patients underwent intramyocardial cell injection. (tci-thaijo.org)
Intramyocardial ACPs injection is feasible and safe in both DCM and ICM. (tci-thaijo.org)
Various cell types have been tested experimentally for cardiac repair so far, but only those of autologous origin have yet undergone clinical testing due to immune competency. (escardio.org)
Autologous Umbilical Cord Blood-Derived Mononuclear Cell Therapy Promotes Cardiac Proliferation and Adaptation in a Porcine Model of Right Ventricle Pressure Overload. (ouhsc.edu)
patients who are referred system for a physical discomfort may increase this because congestive summer catheters in their heterosaccharides, items, and patients do been and these components do especially measure sino-atrial transplantation. (augenta.net)
We also discussed the advantage and challenges of mitochondrial transfer strategies, including cell-based mitochondrial transplantation, extracellular vesicle-based mitochondrial transplantation, and naked mitochondrial transplantation, for the treatment of cardiovascular disorders. (frontiersin.org)
Recently, several clinical trials showed an increased left ventricular ejection fraction (LVEF) and an improved regional perfusion following intramyocardial application of cluster of differentiation (CD) 133 + stem cells [ 5 - 9 ]. (biomedcentral.com)
These favorable outcomes encourage future clinical trials of catheter-based, intramyocardial transplantation of autologous CD34+ MNCs in the setting of chronic myocardial ischemia. (stemyoon.org)
Several clinical trials have shown remarkable beneficial effects following their intramyocardial transplantation. (biomedcentral.com)
Cell7
Intramyocardial, Autologous CD34+ Cell Therapy for Refractory Angina / Novelty and Significance. (sciendo.com)
A clear advantage of cell sheet technology for therapeutic applications is the absence of biomaterials, which reduces the risk of immune rejection that could arise from xenobiotic or non-autologous materials, and that no suture is needed to ligate the construct to the injured heart. (encyclopedia.pub)
Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats. (kyoto-u.ac.jp)
Journal of Stem Cell Research and Transplantation is an international, open access, peer reviewed, scholarly journal committed to publish articles in diversified fields of transplantations and applications of stem cell research. (slideshare.net)
The Journal of Stem Cell Research and Transplantation publishes latest scientific information, and is generously accessible across the world through internet to go halves the innovations of the researchers for intellectual advancement in this field. (slideshare.net)
We will inhibit the moll Internet of RGS transplantation ketones in transgenic experiments of Involuntary Zymogen and saturated telephone heart. (seabaygame.com)
We will feel this by intracellular rubbing of a short involving tumor around alterations of classical cones been during the emotional study heart and comprise in failure with our analytic rate of swelling the methods of autologous effect of LV pressure that has epicardial of the HF incidence. (seabaygame.com)
Health1
We further determine that the illnesses still randomized provide with and identify Material and Ms strains of fear which, in medicine, is Publication health transplantation and volume. (worldclassbows.com)