Intramedullary neoplasms spinal cord neoplasms. Medical search. Frequent questions

In a multi-center retrospective review comparing surgical management of NF2-associated spinal ependymomas with bevacizumab, the researchers concluded that while resection may prevent neurologic deterioration, bevacizumab may be beneficial for patients with significant tumor burden that is not amenable to resection. (medscape.com)
In a meta-analysis by Rijs and Klimek regarding intraoperative neuromonitoring (IONM) for intramedullary spinal cord tumors, IONM had a high sensitivity and specificity, was found to prevent neurologic damage, but limited the extent of tumor resection. (medscape.com)
Scholars@Duke publication: The role of concurrent fusion to prevent spinal deformity after intramedullary spinal cord tumor excision in children. (duke.edu)
Of these, 52 patients with a biopsy-proven intramedullary spinal cord tumor had complete clinical records and radiographic data. (duke.edu)
CONCLUSIONS: In the surgical treatment of patients with intramedullary spinal cord tumors, those that undergo instrumentation or in situ fusion at the time of spinal cord tumor excision are significantly less likely to develop postresection spinal deformity. (duke.edu)
A spinal neoplasm is anyone of many tumor types that are similar to intracranial tumors and involve the spinal cord or its roots. (health-care-clinic.org)
If the tumor is slowly progressive, or If it's treated before the cord degenerates from compression, symptoms are likely to disappear, and complete restoration of function is possible. (health-care-clinic.org)
Total removal of an intramedullary tumor was done, using ultrasonography, operating microscope and ultrasonic aspiration. (unboundmedicine.com)
For the emergency physician, the cell origin of the tumor is less of a concern than the consequent syndromes of spinal cord dysfunction. (medscape.com)
The severity of spinal cord compromise secondary to a tumor spans a wide range. (medscape.com)
Incontinence and decreased sensitivity in the saddle area (buttocks) are generally considered warning signs of spinal cord compression by the tumor. (gloucestershirespinalsurgery.com)
This assesses not only the location of the tumor(s) but also their relationship with the spinal cord and the risk of cord compression. (gloucestershirespinalsurgery.com)
The goals of surgical treatment for spinal tumors can include histologic diagnosis, tumor local control or oncological cure, pain relief, spinal cord decompression and restoration of neurological function, restoration of spine stability, and deformity rectification. (gloucestershirespinalsurgery.com)
Shin, John H. / Intramedullary spinal metastasis of a carcinoid tumor . (elsevierpure.com)
Magnetic resonance imaging (MRI) revealed the tumor localized in the thoracic spinal cord. (unboundmedicine.com)
Intramedullary ependymoma (IE) is adults' mostcommon intramedullary spinal tumor. (magiran.com)
The patient's MRI demonstrated an intramedullary spinal cord tumor extending from the fourth ventricle to T4. (magiran.com)
massive spinal ependymoma is a rare, benign, slow-growing tumor, and patients present symptoms years before diagnosis. (magiran.com)
ACNU CED dramatically regressed enhanced mass lesions and provided local tumor controls in the spinal cord. (elsevierpure.com)
FIGURE 6-3 Epidural tumor in Hodgkin's disease, showing compression of the thoracic spinal cord (Weil stain). (neupsykey.com)
RESULTS: Microscopic and immunohistochemical findings confirmed the diagnosis as a primary intramedullary tumor of adrenal cortical origin. (lookfordiagnosis.com)
CONCLUSION: The occurrence of a primary adrenal tumor in the spinal cord is rare and difficult to explain based on our understanding of embryology . (lookfordiagnosis.com)

Back pain may prompt a bone scan to confirm or exclude spinal metastasis. (wikipedia.org)
Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
We report an intramedullary spinal cord metastasis from a bronchial carcinoid, and discuss its mechanisms and management. (elsevierpure.com)
To our knowledge, an intramedullary spinal cord metastasis from a bronchial carcinoid has been described only once previously. (elsevierpure.com)
Intramedullary spinal cord metastasis (ISCM) is a rarely seen complication of cancer. (unboundmedicine.com)
A 42-year-old male presented with a rare intramedullary spinal cord metastasis from gastric carcinoma manifesting as rapidly worsening motor and sphincter disturbances. (unboundmedicine.com)

OBJECTIVES: Spinal deformity is a common development after laminectomy and resection of pediatric intramedullary spinal cord tumors. (duke.edu)
With modern surgical advances, radical resection of pediatric intramedullary spinal cord tumors (IMSCTs) can be expected to preserve long-term neurological function. (johnshopkins.edu)
Extramedullary tumours are more amenable to resection than intramedullary tumours. (gloucestershirespinalsurgery.com)
Minimally invasive resection of intramedullary ependymoma: Case report. (backbonejournal.com)
Minimally invasive resection of intradural-extramedullary spinal neoplasms. (backbonejournal.com)
Meningiomas are highly vascular brain neoplasms that are often associated with substantial blood loss during surgical resection. (drashokhande.com)

Metastatic lesions are featured in this discussion since they cause 85% of the cases of neoplastic spinal cord compression. (medscape.com)
Metastatic lesions that involve the spinal cord affect about 5-10% of patients with cancer. (medscape.com)
[ 3 ] Approximately 15% of all primary CNS lesions arise from the spinal cord, with an estimated incidence rate of 0.5-2.5 cases per 100,000 population. (medscape.com)
Extranodal Rosai-Dorfman disease with multiple spinal lesions: Arare presentation. (jbstjournal.com)
More than in any other part of the nervous system, pathologic lesions impinging on the spinal cord often originate in the membranes or vertebral column that surround it. (neupsykey.com)
Sagittal T1-weighted postcontrast (middle right) and T2-weighted (bottom) images demonstrate enhancing, expansile, centrally located intramedullary lesions within the spinal cord compatible with ependymomas in this patient with NF2. (neurosurgicalatlas.com)
CT and MRI best depict intracranial lesions, but MRI is more appropriate for examining spinal lesions. (medscape.com)

Metastases to the substance of the cord (intramedullary) are relatively rare. (medscape.com)
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Intramedullary spinal cord metastases from any cancer are rare, and bronchial carcinoids account for only a small fraction of lung cancers. (elsevierpure.com)
Disseminated via the cerebrospinal fluid or by direct parenchymal spread, metastases to the CNS typically invade the brain, spinal cord, and leptomeninges. (biomedcentral.com)

Because intramedullary tumors may extend over several spinal cord segments, their symptoms are more variable than those of extramedullary tumors. (health-care-clinic.org)

The management of spinal cord ependymomas in neurofibromatosis type 2 (NF2) has traditionally been conservative, in contrast to the management of sporadic cases. (medscape.com)
The most common type of intradural-intramedullary tumors are ependymomas and astrocytomas. (wikipedia.org)
Intradural-intramedullary tumors are located within the spinal cord itself, with the most common being ependymomas, astrocytomas, and hemangioblastomas. (wikipedia.org)
Intramedullary tumors, or gliomas (astrocytomas or ependymomas), are comparatively rare, accounting for only about 10% of tumors. (health-care-clinic.org)
Most primary intramedullary spinal cord tumors are astrocytomas or ependymomas . (medscape.com)
The most common intramedullary tumors are gliomas, particularly ependymomas and low-grade astrocytomas. (msdmanuals.com)

abstract = "BACKGROUND: Spinal cord high-grade glioma has poor prognosis. (elsevierpure.com)
Abstract Spinal cord infarction is an uncommon phenomenon, which can be caused by different etiologies, constituting a real diagnostic challenge which can lead to devastating consequences. (bvsalud.org)

Metastatic spinal cord compression usually follows hematogenous dissemination of malignant cells to the vertebral bodies, with subsequent expansion into the epidural space. (medscape.com)
Principles of treating intramedullary cancer are similar to those for epidural spinal cord compression. (medscape.com)
Metastatic tumors that cause epidural cord compression and dysfunction are the most common causes of oncologic CNS injury. (medscape.com)
Depending on the underlying malignancy, 2% to 5% of patients will develop clinical signs and symptoms of epidural spinal cord compression (ESCC) during the course of their disease. (mhmedical.com)
We present a case of a 42-year-old male, an old case of deep vein thrombosis on warfarin and other drugs like quetiapine, aspirin, diclofenac sodium, fenofibrate, atorvastatin, propanolol and citalopram for concurrent illnesses, who presented with widespread mucocutaneous bleeding and epidural spinal hematoma. (ruralneuropractice.com)
The incidence of spontaneous spinal epidural hematoma is about one in one million individuals per year with a male preponderance of 3:1, occurring most commonly between the ages of 42 to 52 years. (ruralneuropractice.com)
Spontaneous spinal epidural hematoma is extremely rare. (sch.ac.kr)
Detailed neurologic examination and spinal magnetic resonance imaging identified extensive, spontaneous spinal epidural hematoma. (sch.ac.kr)
A spinal subdural or epidural hematoma may result from back trauma, anticoagulation or thrombolytic therapy, or, in patients with bleeding diathesis, lumbar puncture [ 1 ]. (sch.ac.kr)
We report sudden hemiplegia by extensive, spontaneous spinal epidural hematoma in an anticoagulated patient with therapeutic range INR. (sch.ac.kr)

The epidemiology, clinical features, radiology, and surgical treatment of such rare intramedullary tumors are discussed. (unboundmedicine.com)

Intradural tumors are located inside the dura mater lining and are further subdivided into intramedullary and extramedullary tumors. (wikipedia.org)
Intradural-intramedullary tumors are located within the dura and spinal cord parenchyma, while intradural-extramedullary tumors are located within the dura but outside the spinal cord parenchyma. (wikipedia.org)
These are further broken down into intramedullary and extramedullary tumors. (wikipedia.org)
Intradural-extramedullary tumors are located within the dura but outside of the spinal cord parenchyma, with the most common being meningiomas and nerve sheath tumors (e.g. schwannomas, neurofibromas). (wikipedia.org)
Extramedullary tumors may be intradural (meningiomas and schwannomas), which account for 60% of all primary spinal cord neoplasms, or extradural (metastatic tumors from breasts, lungs, prostate, leukemia, or lymphomas), which account for 25% of these neoplasms. (health-care-clinic.org)
Spinal tumors are classically grouped into three categories: extradural tumors, intradural extramedullary tumors, and intradural intramedullary tumors ( Fig. 17-1 ). (mhmedical.com)

Three membranes surround the spinal cord: The outermost is the dura mater (dura), the next is the arachnoid, and the innermost is the pia mater (pia) ( Figs 6-1 and 6-2 ). (neupsykey.com)
FIGURE 6-1 Schematic illustration of the relationships between the spinal cord, spinal nerves, and vertebral column (lateral view), showing the termination of the dura (dura mater spinalis) and its continuation as the filum terminale externum. (neupsykey.com)

Other common symptoms of spinal cord compression include muscle weakness, sensory loss, numbness in hands and legs, and rapid onset paralysis. (wikipedia.org)

The diagnosis is challenging, primarily because symptoms often mimic more common and benign degenerative spinal diseases. (wikipedia.org)
The diagnosis of primary spinal cord tumors is very difficult, mainly due to its symptoms, which tend to be wrongly attributed to more common and benign degenerative spinal diseases. (gloucestershirespinalsurgery.com)
The diagnosis of primary spinal cord tumors is difficult, mainly due to their symptoms, which in early stages mimic more common and benign degenerative spinal diseases. (gloucestershirespinalsurgery.com)

The symptoms of spinal tumors are often non-specific, resulting in a delay in diagnosis. (wikipedia.org)
Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. (bvsalud.org)

The spinal cord is surrounded by three layers known as the spinal meninges. (wikipedia.org)
Primary spinal cord tumors arise from the different elements of the CNS, including neurons, supporting glial cells, and meninges. (medscape.com)
FIGURE 6-2 Drawing of a horizontal section through a vertebra and the spinal cord, meninges, and roots. (neupsykey.com)

Evidence of spinal compromise may include lower extremity weakness, paresthesias, reflex asymmetry, and spinal pain. (medscape.com)

Nerve tracts most vulnerable to mechanical pressure include the corticospinal and spinocerebellar tracts and the posterior spinal columns. (medscape.com)
It showed multiloculated cystic mass (11×1.5×1 cm) in spinal canal at posterior and right posterolateral region from C1 to T2 level with mass effect on spinal cord and compressive myelopathy at C6 to 7 at right side ( Fig. 1 ). (sch.ac.kr)

Partial removal of intramedullary gliomas, followed by radiation, may alleviate symptoms for a short time. (health-care-clinic.org)

To evaluate long-term outcomes after surgery and radiation therapy (RT) for spinal myxopapillary ependymoma (MPE). (drjack.world)

Lumbar spine X-rays and spinal cord angiogram were normal, but myelogram and myelo-scan revealed a fusiform enlargement of the conus medullaris. (unboundmedicine.com)
Neoplastic disease that involves the spine with spinal cord compression may be devastating. (medscape.com)
Consequent signs and symptoms may be referable to the spine or spinal cord. (medscape.com)
The future of spine surgery: New horizons in the treatment of spinal disorders. (backbonejournal.com)
Isolated extradural Rosai-Dorfman disease of the thoracic spine: A rare cause of spinal cord compression: Case report. (jbstjournal.com)

Spinal tumors are neoplasms located in either the vertebral column or the spinal cord. (wikipedia.org)

3 Çukurova University Medical Faculty Department of Pathology, Adana Haemangioblastomas are true vascular neoplasms which progress inexorably to a atastrophic clinical situation if left untreated. (turkishneurosurgery.org.tr)
We analyzed the demographic/clinical features of all primary intraspinal tumors (with a specific focus on primary intradural spinal cord tumors) identified between 1992 and 2004 in three of the major related hospitals in Isfahan, Iran. (ac.ir)
Spinal hematoma has been described as a clinical entity since 1850 by Tellegen and in autopsy studies as early as 1682. (ruralneuropractice.com)
The aim of this study was to characterize the radiologic presentation of patients with neurofibromatosis type 1 with widespread spinal disease and to correlate it to clinical presentation and outcome. (ajnr.org)

Most symptoms from spinal tumors occur due to compression of the spinal cord as it plays a primary role in motor and sensory function. (wikipedia.org)
Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from secondary conditions, which result in extrinsic compression of the spinal cord. (bvsalud.org)

Steroids may also be given before surgery in cases of significant cord compression. (wikipedia.org)
Our objective is to compare the occurrence of postlaminectomy spinal deformity in children with intramedullary spinal cord tumors that underwent decompression with fusion at the time of surgery to those that did not undergo fusion. (duke.edu)
Steroid therapy minimizes cord edema until surgery can be performed. (health-care-clinic.org)
The combination of minimally invasive surgery and radiation or chemotherapy is a new technique for treating spinal tumors. (gloucestershirespinalsurgery.com)
Some suggest that direct decompressive surgery combined with postoperative radiotherapy, provide better outcomes than treatment with radiotherapy alone for patients with spinal cord compression due to metastatic cancer. (gloucestershirespinalsurgery.com)
We present a case of spinal cord ischemia in the context of shoulder surgery in a beach chair position. (bvsalud.org)

Spinal cord tumors usually require decompression or radiation. (health-care-clinic.org)
If the patient has incomplete paraplegia of rapid onset, emergency surgical decompression may save cord function. (health-care-clinic.org)

intramedullary tumors, by destroying the parenchyma and compressing adjacent areas. (health-care-clinic.org)

The cauda equina is made up of dorsal and ventral roots that arise from lumbar and sacral segments of the cord. (neupsykey.com)

Primary spinal neoplasms originate in the meningeal coverings, the parenchyma of the cord or its roots, the intraspinal vasculature, or the vertebrae. (health-care-clinic.org)
Spinal tumors may develop within the spinal cord parenchyma, directly destroying tissue, or outside the cord parenchyma, often compressing the cord or nerve roots. (msdmanuals.com)
Intramedullary tumors infiltrate the parenchyma and expand rather than displace the spinal cord. (msdmanuals.com)
Both intradural and extradural tumors exert their effects by compressing the spinal cord and its roots, rather than by invading the parenchyma. (msdmanuals.com)

They are mostly intramedullary tumours rarely seen in the extramedullary space. (turkishneurosurgery.org.tr)

Back pain is a primary symptom of spinal cord compression in patients with known malignancy. (wikipedia.org)
Primary spinal tumors are associated with a few genetic syndromes. (wikipedia.org)
Common primary cancers in metastatic spinal tumors includes breast, prostate, lung, and kidney cancer. (wikipedia.org)
Primary spinal cord tumors may be extramedullary (occurring outside the spinal cord) or intramedullary (occurring within the cord itself). (health-care-clinic.org)
Most primary spinal cord cancers do not disseminate widely through the CNS or body. (medscape.com)
Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
Although primary spinal cord tumors (PSCTs) comprise a minority of primary central nervous system tumors, they often impose a great deal of morbidity on their victims. (ac.ir)

A novel minimally invasive technique for spinal cord untethering. (backbonejournal.com)
BACKGROUND: One of the new treatment options for proximal humeral fractures is the minimally invasive intramedullary nail. (keyopinionleaders.com)

Children may present with spinal deformities such as scoliosis. (wikipedia.org)

Spinal cord tumors are rare compared with intracranial tumors (ratio of 1:4). (health-care-clinic.org)

Spinal cord tumors are classified based on their location within the spinal cord: intradural (intradmedullary and extramedullary) and extradural tumors. (wikipedia.org)
Extradural tumors are more common than intradural neoplasms. (gloucestershirespinalsurgery.com)
Most extradural tumors invade and destroy bone before compressing the spinal cord. (msdmanuals.com)

Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)

Multiple Sclerosis (MS) is a CNS disorder that is characterized by both inflammatory and neurodegenerative mechanisms of brain and spinal cord injury. (medscape.com)
A meningioma is a tumour that forms on membranes that cover the brain and spinal cord just inside the skull . (drashokhande.com)

Rapid identification and intervention of malignant spinal tumors, often causing spinal cord compression, is key to maintaining quality of life in patients. (gloucestershirespinalsurgery.com)

Multiple spinal levels are affected in about 30% of patients. (medscape.com)

Additionally, neoplasms may compromise the vascular supply, causing edema or ischemia. (medscape.com)

Symptoms can include progressive back pain and neurologic deficits referable to the spinal cord or spinal nerve roots. (msdmanuals.com)

1 ] Most spinal hematomas are located dorsally to the spinal cord in the cervicothoracic and thoracolumbar regions. (ruralneuropractice.com)
MRI demonstrated an unenhanced intramedullary mass of the cervicothoracic spinal cord measuring approximately 1.5 cm in greatest axial diameter. (lookfordiagnosis.com)

The cause of spinal tumors is unknown. (wikipedia.org)

Chemotherapy is considered experimental in the treatment of spinal cord tumors. (medscape.com)

Загальні відомості про захворювання спинного мозку Spinal cord disorders can cause permanent severe neurologic disability. (msdmanuals.com)

Spinal cord compression is commonly found in patients with metastatic malignancy. (wikipedia.org)
Intramedullary hemangioblastomas can be seen in patients with von Hippel-Lindau disease. (wikipedia.org)
Spinal cord lymphomas are commonly seen in patients with suppressed immune systems. (wikipedia.org)
METHODS: Two patients developed high-grade glioma in the thoracic spinal cord. (elsevierpure.com)
Indwelling urethral catheter is often used in male spinal cord injury patients to provide drainage to neuropathic bladder. (biomedcentral.com)
We conducted a historical cohort study of adult patients with neurofibromatosis type 1 with spinal involvement. (ajnr.org)

Additionally, cancers that metastasize to the vertebrae or surrounding tissues frequently cause spinal cord compression. (medscape.com)

Preoperative spinal alignment, surgical treatment, postoperative deformity, and risk factors for deformity were evaluated. (duke.edu)

It must be suspected in any patient on anticoagulant agents who complains of local or referred spinal pain associated with neurological deficits. (ruralneuropractice.com)

During the procedure, the infusion cannula was inserted into the spinal cord lesion under intraoperative computed tomography scan. (elsevierpure.com)

in contrast, spinal tumors secondary to metastatic disease tend to be extradural. (mhmedical.com)
The CNS may be primarily afflicted by the virus or by opportunistic infections and neoplasms secondary to the immune suppression caused by the virus. (neurologyindia.com)

There is paucity of data to estimate the incidence of spinal hematoma, perhaps due to the rarity of this disorder. (ruralneuropractice.com)

Anatomy38

Organisms4

Diseases118

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment53

Psychiatry and Psychology3

Phenomena and Processes13

Disciplines and Occupations1

Information Science2

Health Care6

Tumor22

Metastasis6

Resection6

Lesions7

Metastases4

Tumors may extend1

Ependymomas6

Abstract2

Epidural10

Epidemiology1

Extramedullary tumors6

Dura mater2

Symptoms of spinal cord compression in1

Benign3

Diagnosis2

Meninges3

Include lower extremity1

Posterior2

Gliomas1

Ependymoma1

Spine5

Vertebral column1

Clinical4

Compression of the spinal cord2

Surgery6

Decompression2

Destroying the parenchyma1

Cauda equina1

Parenchyma4

Tumours1

Primary7

Minimally2

Scoliosis1

Intracranial1

Extradural tumors3

Infiltrate1

Brain and spinal2

Malignant1

Multiple spinal1

Vascular1

Neurologic deficits1

Cervicothoracic2

Cause of spinal1

Treatment of spinal1

Disorders1

Patients6

Cancers1

Surgical treatment1

Deficits1

Intraoperative1

Secondary2

Incidence1