• It is widely believed that extralobar pulmonary sequestrations are a result of prenatal pulmonary malformation while intralobar pulmonary sequestrations can develop due to recurrent pulmonary infections in adolescents and young adults. (wikipedia.org)
  • citation needed] Bronchopulmonary sequestration (BPS) is a rare congenital malformation of the lower respiratory tract. (wikipedia.org)
  • When this area fails to clear after a course of appropriate medical therapy, the presence of a malformation, such as sequestration, should be considered, particularly if the lesion is localized to the posterior basal segment of the left lower lobe. (medscape.com)
  • Therefore, this article discusses bronchogenic cyst, pulmonary agenesis and hypoplasia, polyalveolar lobe, alveolocapillary dysplasia, sequestration including arteriovenous malformation (AVM) and scimitar syndrome, pulmonary lymphangiectasis, congenital lobar emphysema (CLE), and cystic adenomatoid malformation (CAM) and other lung cysts. (medscape.com)
  • Pulmonary sequestration is a malformation comprised of dysplastic lung tissue without normal communication with the tracheobronchial tree and with an anomalous systemic arterial supply. (johnshopkins.edu)
  • Pulmonary sequestration is classified into two types, intralobar and extralobar based on the location of the malformation and the venous drainage. (johnshopkins.edu)
  • These attachments to the aorta remain to form the systemic arterial supply of the sequestration. (wikipedia.org)
  • Intralobar sequestration in which the lesion is located within a normal lobe and lacks its own visceral pleura. (wikipedia.org)
  • Two thirds of the time, the sequestration is located in the paravertebral gutter in the posterior segment of the left lower lobe. (wikipedia.org)
  • If no communication between sequestration and normal lung tissue is present, radiography usually reveals a dense opacity in the posterior basal segment of the lower lobe. (medscape.com)
  • Alivizatos P, Cheatle T, de Leval M, Stark J. Pulmonary sequestration complicated by anomalies of pulmonary venous return. (medscape.com)
  • Extralobar sequestration is less common than intralobar sequestration and usually has systemic venous drainage into the azygos system. (johnshopkins.edu)
  • Extrapulmonary sequestration is completely enclosed in its own pleural sac. (wikipedia.org)
  • Distinguishing an intrapulmonary sequestration from extrapulmonary sequestration is difficult using plain radiography. (medscape.com)
  • A pulmonary sequestration is a medical condition wherein a piece of tissue that ultimately develops into lung tissue is not attached to the pulmonary arterial blood supply, as is the case in normally developing lung. (wikipedia.org)
  • Early embryologic development of the accessory lung bud results in formation of the sequestration within normal lung tissue. (wikipedia.org)
  • Intrapulmonary sequestration occurs within the visceral pleura of normal lung tissue. (wikipedia.org)
  • When a fetus develops a cystic piece of nonfunctioning abnormal lung tissue either within a lung (intralobar sequestration) or next to it (extralobar- more common in boys) that is not connected to the body's airways, its known as bronchopulmonary sequestration. (nicklauschildrens.org)
  • Because no communication with the bronchial tree occurs, sequestration appears to have loose, spongy tissue with numerous small cystic spaces containing clear, mucoid fluid. (medscape.com)
  • These include: Potentially fatal hemorrhage The creation of a left-right shunt, where blood flows in a shortcut through the feed off the aorta Chronic infection with diseases such as Bronchiectasis Tuberculosis Aspergillosis Bronchial carcinoid Bronchogenic squamous cell carcinoma There is still much debate to whether pulmonary sequestration is a congenital problem or acquired through recurrent pulmonary infection. (wikipedia.org)
  • Bronchopulmonary sequestration may be diagnosed prenatally and have no symptoms during the neonatal period. (nicklauschildrens.org)
  • Clements BS, Warner JO: Pulmonary sequestration and related congenital bronchopulmonary-vascular malformations: nomenclature and classification based on anatomical and embryological considerations. (edu.pl)
  • The most frequently supported theory of sequestration formation involves an accessory lung bud that develops from the ventral aspect of the primitive foregut. (wikipedia.org)
  • BPS, pulmonary sequestration, accessory lung. (nicklauschildrens.org)
  • Both types of sequestration usually have arterial supply from the thoracic or abdominal aorta. (wikipedia.org)
  • Extralobar sequestration in which the mass is located outside the normal lung and has its own visceral pleuraThe blood supply of 75% of pulmonary sequestrations is derived from the thoracic or abdominal aorta. (wikipedia.org)
  • Extralobar sequestration may present with gastrointestinal symptoms i.e feeding difficulties. (nicklauschildrens.org)
  • The sequestration is encased within the same pleural covering. (wikipedia.org)
  • Failure to have a pulmonary sequestration removed can lead to a number of complications. (wikipedia.org)
  • The most common location is in the posterior basal segment, and nearly two thirds of pulmonary sequestrations appear in the left lung. (wikipedia.org)
  • 2. Intralobar sequestration is much more common (87%) than extralobar and is often situated in the basal segments with comparable incidence on the right and left sides. (edu.pl)
  • Unlike extralobar sequestration, it is rarely associated with other developmental abnormalities. (wikipedia.org)
  • Presence of systemic arteries revealed by chest imaging is the major diagnostic feature of pulmonary sequestration. (medscape.com)
  • The aim of the study was to review the clinical characteristics of operated patients with respect to pulmonary sequestration and analyze diagnostic and therapeutic problems connected with this anomaly.Material and methods. (edu.pl)
  • The sequestration (S) is linked by an aberrant vessel (arrows). (medscape.com)
  • We present an interesting and unusual case of extralobar sequestration which presented as a retroperitoneal mass in an asymptomatic adult. (johnshopkins.edu)
  • We performed a retrospective analysis of 23 patients operated on because of pulmonary sequestration between 1963 and 2004 in the Departments of Thoracic Surgery in Zakopane (10 patients) and Szczecin-Zdunowo (13 patients).Results. (edu.pl)
  • Preoperatively, pulmonary sequestration was suspected in 5 patients. (edu.pl)
  • In 5 patients, the pulmonary sequestration was supplied by more than one artery. (edu.pl)
  • Most patients with extralobar sequestration are diagnosed before the age of 10. (johnshopkins.edu)
  • We found 20 intralobar sequestrations and 3 extralobar sequestrations, which were situated above the diaphragm. (edu.pl)
  • There were 11 sequestrations on the right side and 12 on the left side. (edu.pl)