• The most frequent forms are metastatic malignant neoplasm of liver) liver cell carcinoma hepatocellular carcinoma hepatoma cholangiocarcinoma hepatoblastoma angiosarcoma of liver Kupffer cell sarcoma other sarcomas of liver Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas, and focal nodular hyperplasia (FNH). (wikipedia.org)
  • In the absence of any other clinically detectable primary tumor, the lesion was diagnosed as a peripheral intrahepatic cholangiocarcinoma. (nih.gov)
  • Our study investigates CAF functions in intrahepatic cholangiocarcinoma (ICC), a highly desmoplastic liver tumor. (nih.gov)
  • 3. [Evaluation of immunohistochemical markers for differential diagnosis of hepatocellular carcinoma from intrahepatic cholangiocarcinoma]. (nih.gov)
  • The purpose of this study was to prove the safety and efficacy of PHP in patients with unresectable intrahepatic cholangiocarcinoma (iCCA).Patients and methodsWe retrospectively reviewed data from 15 patients with unresectable iCCA treated with PHP in nine different hospitals throughout Europe. (uni-regensburg.de)
  • Pathological examination found chronic bile duct injury with DNA damage, precancerous/preinvasive lesions such as biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct in various sites of the large bile ducts, and invasive cholangiocarcinoma such as mass-forming type and intraductal growth-type intrahepatic cholangiocarcinoma and mainly papillary-type extrahepatic cholangiocarcinoma. (nih.gov)
  • Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. (cdc.gov)
  • Intrahepatic cholangiocarcinoma (ICC) is a malignant epithelial neoplasm composed of cells resembling cholangiocytes that line the intrahepatic bile ducts in portal areas of the hepatic lobule. (elsevierpure.com)
  • The goal of this clinical trial is to test feasibility and safety of the combination of tremelimumab and durvalumab plus gemcitabine and cisplatin as a neoadjuvant treatment bridge patients to a curative resection in treatment naïve borderline resectable, or resectable with high risk for recurrence intrahepatic cholangiocarcinoma patients. (clinicaltrials.gov)
  • Phase II Study of Neoadjuvant Durvalumab (MEDI4736) and Tremelimumab in Combination With Gemcitabine and Cisplatin in Patients With Intrahepatic Cholangiocarcinoma That is Borderline Resectable/Resectable But With High Risk for Recurrence. (clinicaltrials.gov)
  • Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. (biomedcentral.com)
  • LYTGOBI is indicated for the treatment of adult patients with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions or other rearrangements. (lytgobi.com)
  • Studies investigating the association between hepatitis C virus (HCV) infections and the occurrence of cholangiocarcinoma (CCA), especially intrahepatic cholangiocarcinoma (ICC), have shown inconsistent findings. (biomedcentral.com)
  • Cholangiocarcinoma (CCA) is a malignant neoplasm arising from the epithelial cells of the intrahepatic or extrahepatic bile ducts. (biomedcentral.com)
  • Therefore, CCA can be classified as intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC). (biomedcentral.com)
  • The MeSH (Medical Subject Heading) search included headings that were all combinations of the hepatitis C virus such as: HCV, cholangiocarcinoma, intrahepatic, extrahepatic, bile duct cancer, and bile duct neoplasm. (biomedcentral.com)
  • Cholangiocarcinoma (CC) is a fatal neoplasm that arises from cholangiocytes, the epithelial cells lining the bile duct liver. (gastrores.org)
  • Cholangiocarcinoma is the malignant neoplasm of the primary biliary tract, being the intrahepatic type localized in the biliary duct ramifications inside the liver. (resourcenews.com)
  • The FDA approval in the USA is based on a multicenter, open-label, single-arm, multicohort, phase 2 study (FIGHT-202), that evaluated the safety and antitumor activity of pemigatinib in patients with previously treated, locally advanced or metastatic intrahepatic cholangiocarcinoma with and without FGFR2 fusions or rearrangements, in patients aged 18 years or older with disease progression following at least one previous treatment. (resourcenews.com)
  • ALPPS for Locally Advanced Intrahepatic Cholangiocarcinoma: Did Aggressive Surgery Lead to the Oncological Benefit? (ooir.org)
  • Transjugular intrahepatic portosystemic shunt ( TIPS or TIPSS ) is a treatment for portal hypertension in which direct communication is formed between a hepatic vein and a branch of the portal vein , thus allowing some proportion of portal flow to bypass the liver . (radiopaedia.org)
  • Recurrence or metastasis of HCC is mainly intrahepatic, which shows that peritumoral liver tissue may be a favorable soil for spreading hepatoma cells [ 4 ]. (hindawi.com)
  • Here we report a rare case of Caroli's disease limited to one liver segment, which was initially misdiagnosed as an intraductal papillary neoplasm of the bile duct. (e-cmh.org)
  • A 19-year-old captive ovariohysterectomized female African lion from a zoological park in Brazil was presented at the Veterinary Hospital of the São Paulo State University, Botucatu, Brazil, with the suspicion of an intraocular neoplasm with liver metastasis. (biomedcentral.com)
  • Intraductal papillary neoplasm of bile duct (IPNB) is characterized by a spectrum of diseases ranging from low-grade intraepithelial neoplasia to invasive carcinoma. (nih.gov)
  • A carcinoma that originates in the intrahepatic bile duct epithelium of the intrahepatic biliary tree. (nih.gov)
  • Pemigatinib is also the first targeted treatment approved for use in the United States for treatment of adults with relapsed or refractory myeloid/lymphoid neoplasms (MLNs) with FGFR1 rearrangement. (resourcenews.com)
  • intraductal papillary neoplasm of the bile duct. (nih.gov)
  • In this report, we present a case of Caroli's disease that was misdiagnosed as an intraductal papillary neoplasm of the bile duct (IPNB) and was treated with segmentectomy. (e-cmh.org)
  • The data presented for Malignant neoplasm of the colon, sigmoid, rectum and anus (C18-C21) includes deaths due to Malignant neoplasm of the intestinal tract, part unspecified (C26.0). (crsociety.org)
  • Radiology plays an important role in the diagnosis of intrahepatic cystic lesions. (medscape.com)
  • 16. [Immunohistochemical spectrum in the detection and differentiation of intrahepatic neoplasms]. (nih.gov)
  • There was not any finding of duodenal obstruction or pancreatic head neoplasm. (ispub.com)
  • Regional dilatation of intrahepatic bile ducts without tumor-induced obstruction was characteristic in diagnostic imaging. (nih.gov)