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PancreasGallbladderMalignant neoplasmBenignIPMNExtrahepatic bileTumorCarcinomaLesionsEpithelialIntrahepatic ductsDuodenalPancreatobiliary tractDuctalCholangiocarcinomaProximalStenosisFine-needle aspLiverStentDistalDiseasePathologyStricturesHepatocytesResectionAmpullaEtiologyComputed TomographyHistologicallyCommonOriginateExocrineCancers

Pancreas15

• Clinicopathological images of these tumours are distinctive and diverse, including histological images with a low to high grade dysplasia, infiltrating and noninfiltrating characteristics, excessive mucus production , and similarity to intraductal papillary mucinous neoplasm (IPMN) of the pancreas . (bvsalud.org)
• In a retrospective review (2010-2014) of 4 women with either type II cysts, equivocal for choledochal cyst on magnetic resonance imaging (MRI), or the possibility of branch-duct intraductal papillary mucinous neoplasm of the pancreas on computed tomography (CT) scan, EUS was able to demonstrate no communication in all cases between the choledochal structure and the common bile duct. (medscape.com)
• Surgeons at MountainView Regional Medical Center provide care to patients with diseases of the pancreas, liver, gallbladder and bile ducts. (mountainviewregional.com)
• however, it is not detected in the normal pancreas or in chronic pancreatitis.MUC4 is not expressed in normal bile ducts, but it can be overexpressed in intrahepatic cholangiocarcinoma and bile duct cholangiocarcinoma. (chemdict.com)
• A diagnostic procedure using a thin tube, called an endoscope, with an ultrasound tip to take images of the pancreas, bile duct and digestive tract. (uclahealth.org)
• Starts within the exocrine cells, which are in the ducts and exocrine glands of the pancreas. (uclahealth.org)
• This is a critical point in the differentiation of pancreatic pseudocysts from cystic neoplasms of the pancreas. (medscape.com)
• PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
• Yilmaz & Deshpande occasionally, they are cystic and thus can mimic primary cystic neoplasms of the pancreas. (coek.info)
• Recommendations are made for the appropriate use of bile duct brushing cytology obtained via endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS)-fine-needle aspiration (FNA) cytology of mass lesions in the pancreas. (cytojournal.com)
• Tumors of the pancreas that contain substantial cystic components include mainly mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, solid pseudopapillary tumor, and cystadenomas (which encompass microcystic, macrocystic/oligocystic, and rare solid serous adenomas). (hindawi.com)
• The normal anatomy allows the majority of the pancreas to be drained via a single duct, which opens at the ampulla of Vater. (practicalgastro.com)
• If the dorsal duct does not unite with the ventral duct in the pancreatic head, pancreas divisum results, where the majority of pancreatic secretions drain via the minor ampulla. (practicalgastro.com)
• Enzymes leave the pancreas via a system of tubes called 'ducts' that connect the pancreas to the intestines where the enzymes mix with ingested food. (medicinenet.com)
• The pancreas sits deep in the abdomen and is in close proximity to many important structures such as the small intestine (the duodenum) and the bile ducts, as well as important blood vessels and nerves. (medicinenet.com)

Gallbladder6

• [ 1 ] In contrast, bile duct tumors located outside of the liver had been classified with gallbladder cancer as extrahepatic biliary tract tumors. (tri-kobe.org)
• Upper abdominal ultrasound showed dilated intrahepatic and extrahepatic bile ducts and a distended gallbladder. (ispub.com)
• Upper abdominal ultrasound (US) showed dilated intrahepatic and extrahepatic bile ducts and a distended gallbladder. (ispub.com)
• The Clinical and Pathologic Features of Intracholecystic Papillary-Tubular Neoplasms of the Gallbladder. (nih.gov)
• Carcinoid tumors and small-cell carcinomas of the gallbladder and extrahepatic bile ducts: a comparative study based on 221 cases from the Surveillance, Epidemiology, and End Results Program. (cancercentrum.se)
• Should the extrahepatic bile duct be resected or preserved in R0 radical surgery for advanced gallbladder carcinoma? (cancercentrum.se)

Malignant neoplasm3

• A benign, intermediate, or malignant neoplasm characterized by the formation of papillary structures. (nih.gov)
• A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
• Villous or tubulovillous adenomas of the ampulla of Vater are particularly interesting since they may harbor an undetected malignant neoplasm that could become invasive if left untreated. (biomedres.us)

Benign3

• Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
• Colloid carcinoma begins as a benign cyst called an intraductal papillary mucinous neoplasm (IPMN). (uclahealth.org)
• The endoscopic papillectomy procedure is a curative treatment alternative for benign papillary adenomas, but a relatively high risk for procedure-related complications exists and needs more intervention treatment. (biomedres.us)

IPMN1

• Other types include islet cell tumors, pancreatic lymphoma, and cystic tumors, such as intraductal papillary mucinous neoplasms (IPMN or IPMT). (bidmc.org)

Extrahepatic bile6

• Bile duct epithelial tumours showing papillary neoplasm in the bile duct lumen are present in the intrahepatic and extrahepatic bile ducts . (bvsalud.org)
• The bile ducts located outside of the liver are called extrahepatic bile ducts. (tri-kobe.org)
• The extrahepatic bile ducts can be further divided into the perihilar (hilum) region and distal region. (tri-kobe.org)
• Anatomy of the extrahepatic bile duct. (tri-kobe.org)
• Computed Tomography (CT) revealed intrahepatic and extrahepatic bile duct dilation. (ispub.com)
• With the progress in research, scholars have found that besides hepatocytes, intrahepatic and extrahepatic bile ducts can also be attacked by the immune system, leading to the disease known as immune-related cholangitis. (bvsalud.org)

Tumor1

• It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)

Carcinoma3

• The World Health Organization Classification of Tumours of the Digestive System in 2010 named these features, intraductal papillary neoplasm of the bile duct (IPNB), as precancerous lesion of biliary carcinoma . (bvsalud.org)
• Traditionally, bile duct tumors located within the liver had been classified with hepatocellular carcinoma as primary liver tumors. (tri-kobe.org)
• Methods Retrospective single center cohort study of patients who underwent pancreaticoduodenectomy over the past 10 years for carcinoma obstructing the lower common bile duct. (thieme-connect.de)

Lesions1

• 2 Moreover, up to 10% of patients with intraductal papillary mucinous neoplasms (IPMNs), which are pre-malignant lesions, may be initially incorrectly diagnosed with CP. (practicalgastro.com)

Epithelial1

• Figure 2: (A) Papillary lesion with abnormally dispersed glandular structures (HEx50), (B) Dysplasia of the epithelium with extended, pseudostratified hyperchromatic nuclei of crowdy epithelial cells with mucin depletion (HEx200). (ispub.com)

Intrahepatic ducts2

• Tumors of the intrahepatic bile ducts originate in small intrahepatic ductules or large intrahepatic ducts that are proximal to the bifurcation of the right and left hepatic ducts. (tri-kobe.org)
• This causes strictures of the common hepatic duct and main ducts, but spares distal and proximal (i.e. common bile duct and intrahepatic ducts). (radiopaedia.org)

Duodenal3

• According to multiple modalities and lab examination, we made a definite diagnosis of duodenal neoplasm. (biomedres.us)
• A 73-year-old man was admitted into our hospital with the chief complaint that neoplasm of the duodenal papilla was discovered under screening endoscopy for four months. (biomedres.us)
• Endoscopic ultrasonography was then performed, showing a hypoechoic mass at the major duodenal papilla continuing to the lower common bile duct. (biomedres.us)

Pancreatobiliary tract1

• Intraductal neoplasms of the pancreatobiliary tract: navigating the alphabet. (nih.gov)

Ductal2

• In addition, pseudocysts are associated with pancreatic ductal obstruction and pancreatic neoplasms. (medscape.com)
• Location in either the dorsal or the ventral duct, in relationship to dorsal-ventral confluence, may influence the initial ductal access approach, via either the major or minor papilla. (practicalgastro.com)

Cholangiocarcinoma1

• Cancer of the bile duct (also called cholangiocarcinoma) is extremely rare. (tri-kobe.org)

Proximal2

• The hilum is the region where the right and left hepatic ducts exit the liver and join to form the common hepatic duct that is proximal to the origin of the cystic duct. (tri-kobe.org)
• The duct from the distal portion (body/tail) of the dorsal bud unites with the ventral bud duct to form the main PD (of Wirsung), and the residual proximal duct (head) of dorsal bud remains as the accessory PD (of Santorini). (practicalgastro.com)

Stenosis3

• We report a case of mucin-secreting biliary neoplasm of the ampulla of Vater diagnosed peroperatively because of unsuccessful endoscopy due to pyloric stenosis, and successfully treated with transduodenal local excision. (ispub.com)
• It is generally accepted that short-term difficulty consists of pancreatitis, bleeding, perforation, cholangitis, and long-term one is papillary stenosis. (biomedres.us)
• And the routine placement of a pancreatic duct stent to prevent the post-procedure papillary stenosis is recommended by investigators [7,8]. (biomedres.us)

Fine-needle asp1

• Clinical evaluation, imaging studies, indications for cytologic study and preprocedural requirements for duct brushing studies and pancreatic fine-needle aspiration: The Papanicolaou Society of Cytopathology Guidelines. (cancercentrum.se)

Liver7

• The biliary system consists of a network of ducts that carry bile from the liver to the small bowel and is classified by its anatomic location (Figure 1 ). (tri-kobe.org)
• Bile is produced by the liver and is important for fat digestion. (tri-kobe.org)
• The bile ducts located within the liver are called intrahepatic bile ducts. (tri-kobe.org)
• They include part of the right and left hepatic ducts that are outside the liver, the common hepatic duct, and the common bile duct. (tri-kobe.org)
• Bile duct cancer may occur more frequently in patients with a history of primary sclerosing cholangitis, chronic ulcerative colitis, choledochal cysts, or infections with the liver fluke Clonorchis sinensis . (tri-kobe.org)
• Intrahepatic bile duct cancer may be relatively indolent and difficult to clinically differentiate from metastatic adenocarcinoma deposits in the liver. (tri-kobe.org)
• Liver neoplasms. (lookformedical.com)

Stent2

• Stent placement can not only induce pancreatic and bile duct wall inflammation but also introduce infection into the biliopancreatic system, and this may be responsible. (thieme-connect.de)
• Using ERCP, doctors can also place a stent in the bile duct to relieve jaundice (a yellowing of the skin and whites of the eyes). (bidmc.org)

Distal2

• [ 1 ] The classification of bile duct tumors has changed to include intrahepatic tumors of the bile ducts and extrahepatic tumors (perihilar and distal) of the bile ducts. (tri-kobe.org)
• Furthermore, anatomic location of the stricture in the main PD should be distinctly defined as in head, genu, body, or tail, with the knowledge that strictures more distal in the duct may be more challenging to manage endoscopically, via the traditional transpapillary approach. (practicalgastro.com)

Disease1

• Accurate classification, diagnosis and management of pancreatic duct (PD) strictures can pose significant challenges to the treating endoscopists for a variety of reasons, including previously limited diagnostic options, compounded by the underlying disease processes which led to the stricture. (practicalgastro.com)

Pathology1

• Pathology of intraductal papillary mucinous neoplasms. (nih.gov)

Strictures1

• PD strictures secondary to malignancy can either directly involve the duct or extrinsically compress the duct due to mass effect. (practicalgastro.com)

Hepatocytes1

• Hepatic iminodiacetic acid (HIDA) scintigraphy is a nuclear medicine examination that uses a radiolabeled bile salt (technetium-99m) that is given intravenously and is then taken up by the hepatocytes and excreted in the bile. (medscape.com)

Resection2

• The patient underwent surgery and local resection of ampullary neoplasm was performed. (ispub.com)
• After local resection, the bile and pancreatic ducts were reconstructed. (ispub.com)

Ampulla2

• The histopathological examination of the mass of the ampulla of Vater demonstrated intraductal papillary mucinous neoplasm. (ispub.com)
• After surgery, the histopathological examination of the mass of the ampulla of Vater demonstrated an intraductal papillary mucinous neoplasm (Figure 2). (ispub.com)

Etiology1

• Pathologists also struggle with formulating diagnoses, reporting terminology, and determining etiology, particularly on small biopsies, fine needle aspirations and bile duct brushings. (pbpath.org)

Computed Tomography2

• Computed tomography (CT) scan of a choledochal cyst demonstrating intrahepatic extension involving the main left hepatic duct. (medscape.com)
• Computed tomography (CT) scan of a choledochal cyst involving the common hepatic duct. (medscape.com)

Histologically1

• The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)

Common3

• Barteau JA, Castro D, Arregui ME et al (1995) A comparison of intraoperative ultrasound versus cholangiography in the evaluation of the common bile duct during laparoscopic cholecystectomy. (springer.com)
• This region includes the common bile duct and inserts into the small intestine. (tri-kobe.org)
• During surgery the common bile duct and choledochus were found to be dilated. (ispub.com)

Originate1

• A rare pancreatic cancer made up of squamous cells that originate in the pancreatic ducts. (uclahealth.org)

Exocrine1

• Adenocarcinoma usually starts in the exocrine ducts. (uclahealth.org)

Cancers2

• This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of bile duct cancers. (tri-kobe.org)
• Many bile duct cancers are multifocal. (tri-kobe.org)