• Vitamin A metabolism, adipose tissue as an actively secreting endocrine tissue and cerebral venous abnormalities are areas of active study regarding the pathophysiology of idiopathic intracranial hypertension. (bmj.com)
  • Herein, we describe observations of serum markers of glucose metabolism in a cohort of pediatric TBI patients and how these variables are related to parameters of intracranial pathophysiology. (frontiersin.org)
  • The pathophysiology of traumatic brain injury can be divided into primary and secondary injuries. (surgicalneurologyint.com)
  • Spinal CSF leaks cause spontaneous intracranial hypotension (SIH). (thejns.org)
  • While primary brain injury is unpredictable and irreversible, the sequelae of secondary brain injury may be modified by prevention or minimization of recognized exacerbating systemic insults, such as hypotension, hypoxia, and hyperglycemia ( 2 ). (frontiersin.org)
  • Mechanism by which transverse sinus stenosis leads to increase intracranial pressure. (bmj.com)
  • The preferred neuroimaging procedure is a combination of a magnetic resonance image (MRI) of the brain and magnetic resonance venography (MRV) to rule out both an intracranial mass lesion and a dural sinus thrombosis or stenosis. (medscape.com)
  • [ 6 ] Other studies indicated that increased ICP can cause a collapse of the walls of the transverse sinus, which suggests that venous sinus stenosis is a secondary phenomenon. (medscape.com)
  • A common underlying pathology to cases of empty sella both with and without intracranial hypertension may be hemodynamically significant transverse sinus stenosis, which results in altered CSF absorption and expansion of CSF spaces 13 . (radiopaedia.org)
  • Diagnosis of idiopathic intracranial hypertension is suspected clinically and established by brain imaging (preferably MRI with magnetic resonance venography) that has normal results (except for narrowing of the venous transverse sinus). (msdmanuals.com)
  • By definition, the term 'IIH' describes patients with isolated raised ICP-that is, not related to an intracranial disorder, a meningeal process or cerebral venous thrombosis. (bmj.com)
  • An alternative approach is to move these patients into a group termed secondary intracranial hypertension 15 . (radiopaedia.org)
  • There is a short-of-effective medical treatment for secondary inflammation and reducing brain edema in ICH patients. (karger.com)
  • Most patients could survive the initial injury of smaller hemorrhage, but the secondary injury may result in severe neurological deficits and even death [ 4 ]. (karger.com)
  • Idiopathic intracranial hypertension (IIH) is a disease typically manifesting in young female patients with obesity. (elsevier.es)
  • The rate of successful sealing during the primary closure attempt was 96.6% and 3.4% patients needed a secondary attempt. (thejns.org)
  • Clinical short-term outcome at discharge was unchanged in 14 patients and improved in 25 patients, and 19 patients had signs of rebound intracranial hypertension. (thejns.org)
  • 5-7 In a recent study 5 based on duplex sonographic and venographic assessment of extracranial and intracranial veins of 65 MS patients and 235 controls, Zamboni et al claimed a perfect coincidence of MS and venous stenoses in various locations. (bmj.com)
  • It is difficult to determine which patients, if any, would fit in the primary category, as it is increasingly believed that these patients represent either patients with elevated CSF pressures who are nonetheless asymptomatic or patients who have had a previously undiagnosed condition (e.g. idiopathic intracranial hypertension 3 , lymphocytic hypophysitis 6 , Sheehan syndrome 9 , etc. (radiopaedia.org)
  • It is now thought that many of these patients have idiopathic intracranial hypertension and that the empty sella is actually secondary to elevated CSF pressures. (radiopaedia.org)
  • As has been alluded to above, it is difficult to pin down the epidemiology for empty sella without contamination by patients with idiopathic intracranial hypertension . (radiopaedia.org)
  • Patients with idiopathic intracranial hypertension commonly present with a headache, transient visual obscurations, and intracranial noises with some cranial nerves occasionally involved, most commonly CN VI. (biomedcentral.com)
  • Patients affected by IIH commonly present with headache (92%), transient visual obscurations (72%), and intracranial noises (60%) [ 4 ]. (biomedcentral.com)
  • The source of primary intraparenchymal hemorrhage is incompletely understood but human patients often have systemic hypertension with concurrent fibrinoid degeneration of arteries in the brain. (vin.com)
  • All studied patients must be subjected to an emergency neurosurgical procedure of decompressive craniectomy and were monitored with intracranial pressure, brain oxygenation, and temperature. (surgicalneurologyint.com)
  • Is optic nerve sheath diameter a promising screening tool to predict neurological outcomes and the need for secondary decompressive craniectomy in moderate to severe head injury patients? (surgicalneurologyint.com)
  • It can reliably predict the need for secondary DC at an earlier stage before secondary brain damage ensues in these patients. (surgicalneurologyint.com)
  • We reviewed 11 pediatric patients with Lyme-associated secondary intracranial hypertension. (bvsalud.org)
  • Three patients were considered to have fulminant intracranial hypertension because of the severity in their presenting courses. (bvsalud.org)
  • Two of the fulminant intracranial hypertension patients were treated with a temporary lumbar drain in addition to medications, whereas 1 fulminant intracranial hypertension patient was treated exclusively with medical therapy alone. (bvsalud.org)
  • Patients with IH secondary to a determined disorder were excluded from the study. (tau.ac.il)
  • Patients at risk for secondary brain injury from cerebral edema and intracranial hypertension may benefit from sedation. (aitzol.com)
  • Our study suggests that FABP7 may not discriminate between patients with or without intracranial complications. (springeropen.com)
  • Given the challenges presented in managing critically ill ALF patients with potential CE/ICH including the consideration for liver transplant (LT), the development of a noninvasive biomarker with the potential to predict ICH would be of great value, especially given the significant bleeding risks of invasive intracranial pressure monitoring in these coagulopathic patients [ 8 ]. (springeropen.com)
  • Objective: the study sought to identify, in national and international publications, the principal Nursing interventions aimed at patients with intracranial hypertension. (bvsalud.org)
  • Two thematic categories were established for the Nursing interventions aimed at patients with intracranial hyperten- sion: cognitive skills and clinical reasoning, necessary to control neuro-physiological parameters and prevent intracranial hypertension, and evidence-based practices to improve care for neuro-critical patients. (bvsalud.org)
  • To reference this article / Para citar este artículo / Para citar este article de Almeida CM, Pollo CF, Meneguin S. Nursing Interventions for Patients with Intracranial Hypertension: Integrative Literature Review. (bvsalud.org)
  • For example, optic disk swelling might be seen in patients with syphilis as a result of cranial hypertension (papilloedema), inflammatory optic neuritis with papillitis, or optic perineuritis. (cdc.gov)
  • Bergqvist J, Iderberg H, Mesterton J, Bengtsson N, Wettermark B, Henriksson R. Healthcare resource use, comorbidity, treatment and clinical outcomes for patients with primary intracranial tumors: a Swedish population-based register study. (janusinfo.se)
  • The importance of venous sinus pressure is seen in children who develop increased ICP after thrombosis of 1 or more dural sinuses, usually secondary to otitis or mastoiditis . (medscape.com)
  • The brain MRI scan showed a dural ectasia of the optic nerves, a partially empty sella turcica, and a mild herniation of the cerebellar tonsils which we suspected was secondary to intracranial hypertension and not a type 1 Arnold-Chiari malformation ( Fig. 1 ). (elsevier.es)
  • these animals may be predisposed to intracranial hemorrhage. (vin.com)
  • A variety of secondary causes of hemorrhage exist in dogs. (vin.com)
  • Dogs with brain infarction can have associated hemorrhage, as can dogs with intracranial tumors, vasculitis or coagulopathies. (vin.com)
  • this is attributable to diminution of the mass effect secondary to hemorrhage and reorganization or edema resorption. (vin.com)
  • Idiopathic intracranial hypertension is a diagnosis of exclusion and imaging studies should always be performed to rule out other structural and obstructive lesions. (biomedcentral.com)
  • Intracranial pressure (ICP) rises in various neurological and nonneurological conditions and requires rapid diagnosis and treatment due to its fulminant nature. (surgicalneurologyint.com)
  • All those within England with a diagnosis of idiopathic intracranial hypertension were included. (stanford.edu)
  • The patient had remained drowsy and she was managed in the Intensive Care Unit with a presumptive diagnosis of acute meningoencephalitis with a secondary syndrome of inappropriate anti-diuretic hormone (SIADH). (biomedcentral.com)
  • They may also have transient obscuration of vision, diplopia (due to 6th cranial nerve dysfunction), and pulsatile intracranial tinnitus. (msdmanuals.com)
  • We report idiopathic intracranial hypertension presenting with isolated complete unilateral facial nerve palsy, as the sole cranial nerve involved, which is a presentation rarely reported in the literature. (biomedcentral.com)
  • A 40-year-old Hispanic woman with a history of obesity and hypertension presented to our emergency department complaining of bifrontal headache for 3 days associated with nausea, vomiting, transient visual disturbances, and a picture of right-sided cranial nerve VII palsy. (biomedcentral.com)
  • Idiopathic intracranial hypertension should be suspected in obese young women presenting with headache and transient visual complaints and some cranial nerve abnormalities. (biomedcentral.com)
  • In this case report, we aimed to draw attention to the possibility of idiopathic intracranial hypertension presenting with unilateral cranial nerve VII palsy as the only cranial nerve involved, which needs a high index of suspicion by clinicians. (biomedcentral.com)
  • The mechanisms of cranial nerve VII palsy in idiopathic intracranial hypertension are not well understood and prompt further investigation. (biomedcentral.com)
  • Discussions and voting were organised around six pre-specified themes: (1) primary DC for mass lesions, (2) secondary DC for intracranial hypertension, (3) peri-operative care, (4) surgical technique, (5) cranial reconstruction and (6) DC in low- and middle-income countries. (uib.no)
  • The headache can be made worse by any activity that further increases the intracranial pressure, such as coughing and sneezing. (wikipedia.org)
  • A 40-year-old Hispanic woman, with a history of obesity, a body mass index (BMI) of 32, and hypertension, presented to our emergency department (ED) complaining of squeezing bifrontal headache for 3 days. (biomedcentral.com)
  • A 55-year-old woman with a past medical history of hypertension, hyperlipidemia, and iron deficiency anemia presented to the emergency department with three days of headache, nausea, vomiting, and visual changes. (westjem.com)
  • Recognition, evaluation, and appropriate management of these dangerous secondary headaches are critical to preventing long-term disability or death. (nih.gov)
  • Headaches are broadly classified as primary or secondary. (nih.gov)
  • Secondary headaches are the result of other underlying pathology. (nih.gov)
  • Secondary brain injury persists for weeks and may contribute to a further loss of potentially viable cerebral tissue, ultimately worsening neurological outcome ( 1 ). (frontiersin.org)
  • Worsening of edema (associated with secondary injury phenomenon) can result in progression of neurological signs for a short period of 24-72 hours. (vin.com)
  • The secondary injuries are related to increased cell death and poor neurological outcomes. (surgicalneurologyint.com)
  • The primary outcome was successful sealing of the dura, and the secondary outcome was the occurrence of complications. (thejns.org)
  • Idiopathic intracranial hypertension can rarely be associated with an underlying endocrine disorder such as Cushing's syndrome, hyperthyroidism, or with administration of thyroxine or growth hormone. (biomedcentral.com)
  • A 72-year-old woman presented in the emergency unit of Saint-Joseph Hospital, Paris, France, with subacute intracranial hypertension syndrome evolving over the last 2 weeks. (medscape.com)
  • Unfortunately, the tumor progressed after radiotherapy, and the patient died 3 months later of intracranial hypertension syndrome. (medscape.com)
  • Some authors prefer the term 'Pseudo Tumor Cerebri Syndrome' (PTCS) which includes intracranial hypertension that is idiopathic and also secondary to precipitating factors like drugs and medical conditions. (jpgo.org)
  • Common causes of secondary intracranial hypertension include obstructive sleep apnea (a sleep-related breathing disorder), systemic lupus erythematosus (SLE), chronic kidney disease, and Behçet's disease. (wikipedia.org)
  • In recent years, many studies focus on the mechanism of secondary inflammation that can cause brain edema and this may provide new therapy targets for ICH [ 7 ]. (karger.com)
  • Primary brain injury then initiates a complex cascade of secondary molecular and vascular mechanisms culminating in inflammation, edema, impaired cerebral autoregulation, blood-brain barrier disruption, intracranial hypertension, reduced cerebral perfusion, and ultimately neuronal cell death. (frontiersin.org)
  • Idiopathic intracranial hypertension (IIH) is a health condition that results from pressure exerted on the intracranial region of the brain. (healthhearty.com)
  • The multicenter trial also examined a number of secondary outcomes. (elsevierpure.com)
  • Optic nerve sheath diameter (ONSD) has been shown to be a noninvasive and quick method to calculate intracranial pressure (ICP) and subsequent neurologic outcomes, although with variable cutoffs. (surgicalneurologyint.com)
  • Primary or idiopathic cases of intracranial hypertension are usually seen after age 11 years. (medscape.com)
  • Currently, treatments for ICH are focusing on the primary injury including reducing intracranial hypertension, blood pressure control, and rehabilitation. (karger.com)
  • Results: The PubMed search identified 14 articles with primary and/or secondary outcome data from the IIHTT. (elsevierpure.com)
  • Whole-body computed tomography scan and 18 F-fluorodeoxyglucose positron emission tomography/computed tomography scan excluded a secondary lesion from a cancer arising elsewhere in the body, suggesting a primary sellar or suprasellar lesion. (medscape.com)
  • Whether these conditions are secondary to the empty sella or, rather, both the empty sella and endocrinopathy represent the sequelae of previous disease, is unclear. (radiopaedia.org)
  • Herniations of suprasellar structures into the empty sella may occur, especially when the empty sella is secondary in origin, and most of these cases present with visual disturbances due to herniation of the optic chiasm 12 . (radiopaedia.org)
  • The Society of Obstetricians and Gynecologists of Canada (SOGC) released revised guidelines that simplified the classification of hypertension in pregnancy into four categories, pre-existing hypertension, gestational hypertension, preeclampsia, or "other hypertensive effects" on the basis of different diagnostic considerations. (medscape.com)
  • We report a case of severe preeclampsia that tested positive for antinuclear antibodies, and had idiopathic intracranial hypertension in the past. (jpgo.org)
  • Acute-onset, severe hypertension that is accurately measured using standard techniques and is persistent for 15 minutes or longer is considered a hypertensive emergency. (medscape.com)
  • Intravenous (IV) labetalol and hydralazine have long been considered first-line medications for the management of acute-onset, severe hypertension in pregnant women and women in the postpartum period. (medscape.com)
  • We describe a case of an acute adrenal insufficiency precipitated by idiopathic intracranial hypertension in a Caucasian female. (biomedcentral.com)
  • This case suggests that idiopathic intracranial hypertension can rarely be associated with Addison's disease and present as an acute illness. (biomedcentral.com)
  • Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with significant mortality due to intracranial hypertension (ICH), a result of cerebral edema (CE) and astrocyte swelling. (springeropen.com)
  • The secondary causes commonly observed are delayed treatment of sleep apnea, chronic kidney diseases, and systemic lupus erythematosus. (healthhearty.com)
  • Visual loss secondary to optic nerve drusen. (aetna.com)
  • It is essential to perform urgent neuroimaging studies on any patient presenting with bilateral optic nerve edema in order to rule out an intracranial mass. (medscape.com)
  • Intracranial pressure may be increased due to medications such as high-dose vitamin A derivatives (e.g., isotretinoin for acne), long-term tetracycline antibiotics (for a variety of skin conditions). (wikipedia.org)