Intracellular tyrosine kinase domain. Medical search. Frequent questions

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Anatomy17

Cell Line 3T3 Cells Cells, Cultured Cell Line, Tumor Tumor Cells, Cultured COS Cells Cell Membrane HeLa Cells Cytoplasm CHO Cells Fibroblasts Cell Nucleus NIH 3T3 Cells Cell Line, Transformed Jurkat Cells PC12 Cells HEK293 Cells

Organisms6

Rats, Mutant Strains Cercopithecus aethiops Cricetinae Escherichia coli Mice, Knockout Saccharomyces cerevisiae

Diseases7

Pain Insensitivity, Congenital Hypohidrosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cell Transformation, Neoplastic Lung Neoplasms Carcinoma, Non-Small-Cell Lung Adenocarcinoma

Chemicals and Drugs143

Protein-Tyrosine Kinases Tyrosine Receptor Protein-Tyrosine Kinases Phosphotyrosine Receptor, Epidermal Growth Factor Protein Kinase Inhibitors Recombinant Proteins Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins Protein Kinases Protein-Serine-Threonine Kinases src-Family Kinases Proto-Oncogene Proteins c-abl fms-Like Tyrosine Kinase 3 Pyrimidines Recombinant Fusion Proteins Receptor, Insulin Protein Tyrosine Phosphatases Benzamides Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-kit Piperazines Quinazolines Proto-Oncogene Proteins pp60(c-src)Proto-Oncogene Proteins c-ret Enzyme Inhibitors Phosphoproteins Janus Kinase 2 Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptor, trkA Protein Kinase C Receptors, Fibroblast Growth Factor Proto-Oncogene Proteins c-met Receptor, Fibroblast Growth Factor, Type 5 Genistein Intracellular Signaling Peptides and Proteins Fusion Proteins, bcr-abl Tyrosine 3-Monooxygenase RNA, Messenger Mitogen-Activated Protein Kinase 1 Antineoplastic Agents DNA Primers Receptor, Fibroblast Growth Factor, Type 1 Adaptor Proteins, Signal Transducing DNA-Binding Proteins Cyclic AMP-Dependent Protein Kinases Proto-Oncogene Proteins c-fyn p38 Mitogen-Activated Protein Kinases Epidermal Growth Factor Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 DNA, Complementary Focal Adhesion Kinase 2 Mitogen-Activated Protein Kinase Kinases Ligands Membrane Proteins p21-Activated Kinases Focal Adhesion Protein-Tyrosine Kinases Receptors, Platelet-Derived Growth Factor JNK Mitogen-Activated Protein Kinases Isoenzymes Focal Adhesion Kinase 1 Proteins DNA Receptors, Cell Surface Receptors, Growth Factor Phosphotransferases (Alcohol Group Acceptor)STAT5 Transcription Factor Tyrphostins MAP Kinase Kinase Kinases Drosophila Proteins Milk Proteins Trans-Activators Receptor, erbB-2 Receptors, Nerve Growth Factor Carrier Proteins Ribosomal Protein S6 Kinases Vanadates Quinones Extracellular Signal-Regulated MAP Kinases Proto-Oncogene Proteins c-akt Phospholipase C gamma Cyclin-Dependent Kinases CDC2 Protein Kinase Serine Indoles Transcription Factors Lactams, Macrocyclic Protein Tyrosine Phosphatase, Non-Receptor Type 11 eIF-2 Kinase MAP Kinase Kinase 1 Calcium Benzoquinones Nerve Growth Factors Oncogene Proteins, Fusion Type C Phospholipases Receptor, Fibroblast Growth Factor, Type 3 Casein Kinase II Receptor, IGF Type 1 GRB2 Adaptor Protein Creatine Kinase 1-Phosphatidylinositol 4-Kinase MAP Kinase Kinase 4 Peptides Ribosomal Protein S6 Kinases, 90-kDa Casein Kinases Adenosine Triphosphate Nuclear Proteins Protein Tyrosine Phosphatase, Non-Receptor Type 6 Cell Cycle Proteins Threonine Staurosporine Janus Kinase 1 Janus Kinase 3 Protein Kinase C-delta Glutathione Transferase Pyruvate Kinase rho-Associated Kinases Enzyme Precursors Glycogen Synthase Kinase 3 Protein Tyrosine Phosphatase, Non-Receptor Type 1 Peptide Fragments ZAP-70 Protein-Tyrosine Kinase TYK2 Kinase Cytoskeletal Proteins I-kappa B Kinase Thymidine Kinase Protein Kinase C-alpha Pyridines Nerve Tissue Proteins 3-Phosphoinositide-Dependent Protein Kinases Isoflavones RNA, Small Interfering Proto-Oncogene Proteins c-hck Aurora Kinases Receptor, EphB2 Androstadienes Protein Isoforms Nitriles Pyrroles Phosphoserine Oncogene Proteins v-abl CDC2-CDC28 Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Transfection Cloning, Molecular Models, Molecular Mutagenesis, Site-Directed DNA Mutational Analysis Crystallography, X-Ray Sequence Alignment Blotting, Western Immunoblotting Precipitin Tests Amino Acid Substitution Polymerase Chain Reaction Models, Biological Two-Hybrid System Techniques Immunohistochemistry Electrophoresis, Polyacrylamide Gel Peptide Mapping Immunoprecipitation Microscopy, Fluorescence Reverse Transcriptase Polymerase Chain Reaction

Phenomena and Processes59

Phosphorylation Signal Transduction Amino Acid Sequence Enzyme Activation Transfection Base Sequence Mutation Protein Structure, Tertiary Kinetics src Homology Domains MAP Kinase Signaling System Protein Binding Sequence Homology, Amino Acid Binding Sites Point Mutation Genes, erbB-1 Protein Conformation Sequence Deletion Structure-Activity Relationship Dimerization Cell Division Mutation, Missense Drug Resistance, Neoplasm Amino Acid Substitution Protein Interaction Domains and Motifs Gene Expression Amino Acid Motifs Exons Substrate Specificity Proto-Oncogenes Apoptosis Oncogenes Protein Structure, Secondary Phenotype Protein Transport Dose-Response Relationship, Drug Time Factors Gene Expression Regulation Cell Proliferation Protein Processing, Post-Translational Transcription, Genetic Conserved Sequence Mutagenesis Cell Adhesion Cell Movement Gene Expression Regulation, Enzymologic Catalytic Domain Down-Regulation Tandem Repeat Sequences Cell Survival Plasmids Catalysis Genes, src Sequence Homology, Nucleic Acid Cell Differentiation Genes, abl Molecular Weight Protein Multimerization Cell Cycle

Disciplines and Occupations1

Immunohistochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science

Protein-Tyrosine Kinases Tyrosine Receptor Protein-Tyrosine Kinases Phosphorylation Signal Transduction Molecular Sequence Data Phosphotyrosine Amino Acid Sequence Receptor, Epidermal Growth Factor Cell Line Enzyme Activation Transfection Protein Kinase Inhibitors Base Sequence Recombinant Proteins Mutation Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins Protein Structure, Tertiary Protein Kinases Protein-Serine-Threonine Kinases Kinetics src-Family Kinases src Homology Domains Proto-Oncogene Proteins c-abl fms-Like Tyrosine Kinase 3 Pyrimidines MAP Kinase Signaling System Protein Binding Sequence Homology, Amino Acid Recombinant Fusion Proteins Binding Sites Receptor, Insulin Protein Tyrosine Phosphatases 3T3 Cells Benzamides Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-kit Piperazines Pain Insensitivity, Congenital Cloning, Molecular Quinazolines Proto-Oncogene Proteins pp60(c-src)Proto-Oncogene Proteins c-ret Models, Molecular Enzyme Inhibitors Mutagenesis, Site-Directed Phosphoproteins Cells, Cultured Janus Kinase 2 DNA Mutational Analysis Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptor, trkA Protein Kinase C Receptors, Fibroblast Growth Factor Point Mutation Crystallography, X-Ray Proto-Oncogene Proteins c-met Receptor, Fibroblast Growth Factor, Type 5 Hypohidrosis Genistein Sequence Alignment Intracellular Signaling Peptides and Proteins Fusion Proteins, bcr-abl Blotting, Western Genes, erbB-1 Tyrosine 3-Monooxygenase Cell Line, Tumor RNA, Messenger Mitogen-Activated Protein Kinase 1 Antineoplastic Agents Protein Conformation Sequence Deletion Structure-Activity Relationship Tumor Cells, Cultured DNA Primers Dimerization Receptor, Fibroblast Growth Factor, Type 1 Cell Division Adaptor Proteins, Signal Transducing DNA-Binding Proteins Immunoblotting Cyclic AMP-Dependent Protein Kinases Proto-Oncogene Proteins c-fyn Leukemia, Myelogenous, Chronic, BCR-ABL Positive Mutation, Missense p38 Mitogen-Activated Protein Kinases Cell Transformation, Neoplastic Epidermal Growth Factor Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 DNA, Complementary Focal Adhesion Kinase 2 Mitogen-Activated Protein Kinase Kinases Drug Resistance, Neoplasm Precipitin Tests Ligands Amino Acid Substitution Membrane Proteins p21-Activated Kinases

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