Intestinal pseudo obstruction. Medical search. Frequent questions

Clinical features mimic those seen with mechanical intestinal obstructions and can include abdominal pain, nausea, abdominal distension, vomiting, dysphagia and constipation depending upon the part of the gastrointestinal tract involved. (wikipedia.org)
A functional rather than mechanical obstruction of the intestines, associated with manifestations that resemble those caused by an intestinal obstruction, including distension, abdominal pain, nausea, vomiting, constipation or diarrhea, in an individual in whom a mechanical blockage has been excluded. (nih.gov)
Six children presented with constipation and/or obstruction between 1 and 6 months of age and in 6 other patients diagnosis was made between the ages of 1 and 12 years. (elsevierpure.com)
The test records and helps diagnose conditions including intestinal pseudo-obstruction, gastroparesis, colonic inertia, rapid gastric emptying and constipation. (ucsd.edu)
[ 6 ] idiopathic megacolon/chronic constipation, chronic long-standing constipation of any etiology, and intestinal pseudo-obstruction (Ogilvie syndrome). (medscape.com)
These disorders include esophageal achalasia, gastroparesis, intestinal pseudo-obstruction, Hirschsprung disease and slow transit constipation. (iffgd.org)
Affected individuals can develop constipation and partial or total obstruction of the bowels. (rarediseases.org)
05). While functional dyspepsia, IBS with diarrhea, diarrhea, and fecal incontinence were not specific to Parkinson's disease, IBS with constipation and intestinal pseudo-obstruction showed specificity to Parkinson's disease in the case-control (OR, 4.11) and cohort (RR, 1.84) analyses. (medscape.com)

We evaluated the myoelectrical and motor function of the esophagus, small intestine, colon and anal sphincter in four patients with chronic idiopathic intestinal pseudo-obstruction. (nih.gov)
Background and aim: Chronic idiopathic intestinal pseudo-obstruction (CUP) is characterised by severe impairment of intestinal propulsive motility that mimics bowel obstruction. (elsevierpure.com)

Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder characterized by an impairment of coordinated propulsive activity in the gastrointestinal (GI) tract, which clinically mimics mechanical intestinal obstruction. (nih.gov)
Because some patients have disorders of the nerves or muscles of the gastrointestinal tract, the movement of food down the gastrointestinal tract may be so disorganized that they develop intestinal failure needing intravenous nutrition. (cincinnatichildrens.org)
Though human biopsy samples of functional bowel disorders are difficult to obtain for obvious reasons, animal studies have provided ambiguous results regarding concentrations of nNOS in nerve terminals in pathological states ( 9 , 10 ), which phenotypically manifest as either failure of relaxation of intestinal smooth muscles or varying degrees of impairment of gastrointestinal transit ( 11 , 12 ). (frontiersin.org)
Бактеріальний ріст тонкої кишки (SIBO) Small intestinal bacterial overgrowth can result from alterations in intestinal anatomy or gastrointestinal motility, or lack of gastric acid secretion. (msdmanuals.com)
It plays a central role in controlling the regulation of gastrointestinal motility, absorption of nutrients, and control of the intestinal barrier that protects the body from external pathogens. (medscape.com)
The gastrointestinal signs, especially proventricular dilatation, are secondary to pseudo-obstruction brought about by damage to the enteric nervous system. (cdc.gov)

Intestinal pseudo-obstruction (IPO) is a clinical syndrome caused by severe impairment in the ability of the intestines to push food through. (wikipedia.org)
The intestines act like there is an obstruction even when there isn't one. (childrens.com)
This "imitation" obstruction can cause partially digested food to build up in the intestines, leading to vomiting, abdominal swelling and pain. (childrens.com)

A diagnostic work-up may include: Gastric motility studies Imaging studies: X-rays - may show intestinal air fluid levels (seen with true mechanical intestinal obstruction) CT scans Barium enema Blood tests Upper and lower endoscopies Manometry - used to measure pressure of esophagus and stomach Treatment for IPO (acute or chronic) is aimed at removing the disease process and/or managing the complications present. (wikipedia.org)

One retrospective study estimated mortality to be between 10 and 25% for chronic intestinal pseudo-obstruction (CIPO) and to vary greatly depending on the etiology of the condition. (wikipedia.org)
Despite careful histological study pointing to 2 main forms, myopathy and neuropathy, the etiology of primary intestinal pseudoobstruction syndromes remains unknown. (elsevierpure.com)

We help treat symptoms commonly associated with intestinal motility disorders such as bloating, nausea, abdominal discomfort, weight loss, and diarrhea. (ucsd.edu)
Colonic pseudo-obstruction, also called Ogilvie's syndrome, occurs due to impaired intestinal propulsion, and may be caused by electrolyte imbalances such as hypokalemia and some endocrine disorders such as hyperparathyroidism. (bvsalud.org)
In the remainder of the small bowel (jejunum and ileum), diverticula occur in up to 5% of patients, occur most commonly in the jejunum, and are more common among patients with disorders of intestinal motility. (msdmanuals.com)

Neostigmine may be used to treat intestinal pseudo-obstruction that is only in the large bowel (Ogilvie syndrome). (medlineplus.gov)

Chronic colonic pseudo-obstruction (CCPO) also exists and should be distinguished from patients with ACPO. (medscape.com)
A 73-year-old female with a history of hypertension and parathyroid adenoma presented with recurrent colonic pseudo-obstruction and chronic hypokalemia. (bvsalud.org)

Criteria for CCPO include symptoms of recurrent bowel obstruction in the last 6 months, abdominal bloating and/or pain in the previous 3 months, evidence of bowel obstruction on radiographic imaging, and no evidence of anatomic/structural abnormality. (medscape.com)
The Intestinal Transplant Program at Cincinnati Children's provides comprehensive, innovative care for patients with short bowel syndrome , congenital enteropathies and pseudo-obstructions. (cincinnatichildrens.org)
Other patients have the option of undergoing autologous intestinal reconstructive surgery (e.g., bowel lengthening and tapering) in order to preserve bowel function and avoid transplant. (cincinnatichildrens.org)
When an isolated intestinal transplant is considered, the native stomach, small bowel, and liver are maintained and the only organ transplanted is the small intestine. (cincinnatichildrens.org)
New technology is changing the course of intestinal diagnoses, offering advanced measuring capability of the rate of gut transit time and muscle contractions through the small bowel. (ucsd.edu)
[ 9 ] The use of TAC as the primary immunosuppressant in small bowel transplantation as well as improved surgical techniques, the availability of an increased array of potent immunosuppressive medications, infection prophylaxis, and suitable patient selection have contributed to the reality of this procedure for a growing number of patients who are total parenteral nutrition (TPN)-dependent and have permanent intestinal failure. (medscape.com)

They should be educated regarding the signs and symptoms of recurrent pseudo-obstruction and should be informed that recurrent abdominal distention warrants prompt medical attention. (medscape.com)
Severe recurrent episodes of obstruction which required parenteral nutrition (PN) occurred in all patients. (elsevierpure.com)

Intestinal pseudo-obstruction is a condition in which there are symptoms of blockage of the intestine (bowels) without any physical blockage. (medlineplus.gov)
In intestinal pseudo-obstruction, the intestine is unable to contract and push food, stool, and air through the digestive tract. (medlineplus.gov)
The term intestinal pseudo-obstruction denotes a syndrome characterized by a clinical picture suggestive of mechanical obstruction in the absence of any demonstrable evidence of such an obstruction in the intestine. (medscape.com)
Some CIP researchers have performed full thickness biopsies of the small intestine and discovered an infiltration of lymphocytes in the tissues of some persons with pseudo-obstruction (PWP) that may suggest an autoimmune disease. (grimtrojan.com)
When liver failure complicates intestinal failure, we transplant the liver along with the intestine. (cincinnatichildrens.org)
Overgrowth of bacteria in the small intestine is known as small intestinal bacterial overgrowth (SIBO). (ucsd.edu)

Curry-Jones syndrome (CRJS) is a multisystem disorder characterized by patchy skin lesions, polysyndactyly, diverse cerebral malformations, unicoronal craniosynostosis, iris colobomas, microphthalmia, and intestinal malrotation with myofibromas or hamartomas (summary by Twigg et al. (nih.gov)
The aim of this study was to report the presentation and outcome of 22 consecutive children (13 female) who presented with a syndrome of chronic intestinal pseudo-obstruction with or without urinary tract involvement. (elsevierpure.com)

These studies suggest that in this disorder, physiologic neural responses to swallowing or intestinal distension are impaired but the intestinal smooth-muscle slow-wave activity and the spike and motor responses to exogenous neurohormonal stimulation are intact. (nih.gov)

It is a difficult condition to diagnose, requiring exclusion of any other mechanical cause of obstruction. (wikipedia.org)
Mechanical causes of intestinal obstruction must be excluded to reach a diagnosis of pseudo-obstruction. (wikipedia.org)
The diagnostic approach includes the need for investigations to exclude mechanical GI obstruction, screening for causes of secondary CIPO and the identification of the disease phenotype as well as the prompt recognition and treatment of complications such as malnutrition and small intestinal bacterial overgrowth. (nih.gov)

Housed in a nationally ranked center for Pediatric Intestinal Rehabilitation , Pediatric Gastroenterology and Pediatric Neurogastroenterology and Motility , our team includes a wide range of specialists including gastroenterologists, pediatric surgeons, dieticians and psychologists. (childrens.com)

This animated video explains what is pediatric Chronic Intestinal Pseudo-Obstruction (Cipo), what causes it, how it is diagnosed and what are the management therapies. (poic-e-dintorni.org)

Elevated levels are associated with acute and chronic renal insufficiency and urinary tract obstruction. (cdc.gov)

Symptoms indicative of advanced disease and possible intestinal failure include diarrhea, loss of appetite, sepsis, bloating, fatigue, signs of low volume status, and malabsorption including nutritional deficiencies and foul-smelling stools. (wikipedia.org)
Secretory diarrhea due to intestinal pseudo-obstruction can cause hypokalemia. (bvsalud.org)

If your child's digestive system doesn't work properly because of pediatric megacystic microcolon intestinal hypoperistalsis (MMIHS), specialists at Children's Health℠ provide the diligent, long-term care they need. (childrens.com)
What is Pediatric Megacystic Microcolon Intestinal Hypoperistalsis? (childrens.com)
What are the signs and symptoms of Pediatric Megacystic Microcolon Intestinal Hypoperistalsis? (childrens.com)
How is Pediatric Megacystic Microcolon Intestinal Hypoperistalsis diagnosed? (childrens.com)
How is Pediatric Megacystic Microcolon Intestinal Hypoperistalsis treated? (childrens.com)

Definitive diagnosis of PDD requires demonstration of lymphoplasmacytic ganglioneuritis in the intestinal tract. (cdc.gov)

The exact pathophysiology of intestinal pseudo-obstruction remains to be elucidated. (medscape.com)

It is characterized by the signs and symptoms of intestinal obstruction without any lesion in the intestinal lumen. (wikipedia.org)

Most cases of acute pseudo-obstruction get better in a few days with treatment. (medlineplus.gov)
[ 1 ] On the basis of the clinical presentation, pseudo-obstruction syndromes can be divided into acute and chronic forms. (medscape.com)

Chronic Intestinal Pseudo-Obstruction (CIP) is a neuromuscular disease of the intestinal tract affecting gut motility, the pathogenesis of which is unclear. (grimtrojan.com)

After potassium replacement therapy, the patient's pseudo-obstruction completely resolved. (medscape.com)

Intestinal malrotation. (childrens.com)

The patients did not have a normal increase in duodenal spike or motor activity after intestinal distension, but duodenal activity increased after stimulation with intravenous secretin. (nih.gov)
Ten patients had signs of intestinal obstruction at birth, in which 6 presented antenatally with megacystis on ultrasound. (elsevierpure.com)
Some patients are able to avoid it by participating in our Intestinal Rehabilitation Program, which offers extensive treatment options and training to help patients manage their long-term medical needs. (cincinnatichildrens.org)

They are at such risk that they need small intestinal transplantation as well. (cincinnatichildrens.org)

Small intestinal motor and sensory function and dysfunction. (medlineplus.gov)

Anatomy37

Diseases118

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment75

Psychiatry and Psychology1

Phenomena and Processes18

Technology, Industry, Agriculture1

Information Science1

Named Groups1

Health Care9

Constipation8

Idiopathic2

Gastrointestinal6

Intestines3

Gastric1

Etiology2

Disorders3

Ogilvie1

Colonic pseudo-obst2

Bowel6

Recurrent2

Intestine6

Syndrome2

Disorder1

Mechanical3

Neurogastroenterology1

CIPO1

Urinary1

Diarrhea2

Pediatric5

Diagnosis1

Pathophysiology1

Signs and symptoms1

Acute2

Tract1

Patient's1

Malrotation1

Patients3

Transplantation1

Dysfunction1