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  • patients
  • It is known that 30% of MS patients are non-responsive to Beta interferon. (wikipedia.org)
  • Moreover, a subset of RRMS patients with specially active MS, sometimes called "rapidly worsening MS" are normally non-responders to interferon beta 1a. (wikipedia.org)
  • Nevertheless, recommendation is that all patients should be monitored through laboratory blood analyses, including liver function tests, to ensure safe use of interferons. (wikipedia.org)
  • treatment
  • Also over time, a visible dent at the injection site due to the local destruction of fat tissue, known as lipoatrophy, may develop, however this rarely occurs with interferon treatment. (wikipedia.org)
  • cells
  • Interferon-beta can also reduce numbers of white blood cells (leukopenia), lymphocytes (lymphopenia) and neutrophils (neutropenia), as well as affect liver function. (wikipedia.org)