• In this condition, the alpha intercalated cells of the cortical collecting duct of the distal nephron fail to secrete acid into the urine. (medscape.com)
  • Striated ducts are well developed in this salivary gland. (digitalhistology.org)
  • Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. (medtigo.com)
  • SOX10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: a clue to the histogenesis for tumor diagnosis. (peixesradamar.es)
  • The nephron cortical collecting duct (CCD) is composed of principal cells, which mediate Na, K, and water transport, and intercalated cells (ICs), which are specialized for acid-base transport. (jci.org)
  • SLC22A13 catalyzes unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in renal collecting duct. (uni-koeln.de)
  • More recent studies exhibited that adult acinar, islet, and centroacinar cells (intercalated duct cells located in the acinus) also have the potential to initiate invasive carcinoma, but each cellular context may require a different combination of genetic and/or environmental factors (3, 40, 41). (technuc.com)
  • A single lobule shows the relationship of the secretory acini and the draining duct system. (digitalhistology.org)
  • Intercalated ducts drain individual acini and then form intralobular, striated ducts. (digitalhistology.org)
  • It is composed of approximately one million 'berry-like' clusters of cells called acini, connected by short intercalated ducts. (teachmeanatomy.info)
  • The expression of EGF in striated tube, intercalated duct epithelial cells and serous acinus of Tibetan sheep were significantly lower than that of Big-tail sheep, and the positive expression of EGFR in submandibular gland of Tibetan sheep was higher than that of Big-tail sheep. (xml-data.org)
  • the eNOS was positive in serous acinus and striated duct in both of the two kinds of sheep. (xml-data.org)
  • Taken together, we suggest that the submandibular gland in Tibetan sheep mainly contain serous acinus and strongly positive expression of EGF in submandibular gland of both two kinds of sheep in striated duct basilar membrane, indicating that EGF is mainly secreted in striated duct and the binding sites of EGF and EGFR are mainly in striated duct basilar membrane. (xml-data.org)
  • The largest of all, the sublingual duct (of Bartholin) joins the submandibular duct to drain through the sublingual caruncle. (wikipedia.org)
  • Zenk, J., Hosemann, W. G. & Iro, H. Diameters of the main excretory ducts of the adult human submandibular and parotid gland: a histologic study. (nature.com)
  • intralobular duct of submandibular has striations at the basal surface of their cells. (brainscape.com)
  • clarification needed] The sublingual gland is constituted by 1 major duct and approximately 20 small excretory ducts, with the latter often being referred to as ducts of Rivinus. (wikipedia.org)
  • The excretory duct basal cells inevitably lead to the intercalated ducts, which subsequently give rise to the acinar units and striated ducts. (medtigo.com)
  • The excretory duct basal cells and intercalated duct progenitor cells are capable of tumor formation and cellular division. (medtigo.com)
  • This theory holds that tumors arise from 1 of 2 undifferentiated stem cells: the excretory duct reserve cell or the intercalated duct reserve cell. (medscape.com)
  • Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
  • Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
  • The intercalated ducts unite with those draining adjacent lobules and drain into a network of intralobular collecting ducts , which in turn drain into the main pancreatic duct. (teachmeanatomy.info)
  • Sarcomatoid differentiation also occurs in around 29% of carcinomas of the collecting duct of Bellini. (medscape.com)
  • Rhabdoid differentiation is found in 3-7.5% of RCCs, most commonly in CCRCC, although rare cases have been reported involving papillary RCC, chromophobe RCC, and collecting duct (Bellini duct) carcinoma. (medscape.com)
  • Conversation The 171099-57-3 ductal morphology of PDAC suggests that it derives from the ductal epithelium or from adult progenitor/stem cells capable of differentiating into duct-like cells. (technuc.com)
  • Dent's disease - is an X-linked defect in a Cl-/H+ exchanger expressed in the proximal tubules and collecting duct intercalated cells. (renalfellow.org)
  • Of main importance, a phenotypic switch transforming adult pancreatic acinar cells (the most numerous pancreatic cell type) to duct-like cells can lead to pancreatic intraepithelial neoplasia (PanIN) and eventually to PDAC, but only in conjunction with chemically induced pancreatitis (3, 4, 39, 42). (technuc.com)
  • Striated ducts converge at the center of the lobule eventually forming an interlobular duct that exists the lobule. (digitalhistology.org)
  • The cells of the inner medullary collecting duct (IMCD) are key elements of the nephron in the process of urinary concentration and dilution [ 1 ]. (biomedcentral.com)
  • Chromophobe renal cell carcinoma is a rare subtype of renal cell carcinoma, originating from the intercalating cells of the collecting ducts and macroscopically manifesting as a well-circumscribed, highly lobulated, solid tumor that is usually diagnosed at an early stage. (nih.gov)
  • Most of the remaining small sublingual ducts (of Rivinus) open separate into the mouth on an elevated crest of mucous membrane, the plica sublingualis (aka sublingual fold), formed by the gland and located on either side of the frenulum linguae. (wikipedia.org)
  • These buds branch and form into cords that canalize to form the sublingual ducts associated with the gland. (wikipedia.org)
  • Rana, R., Minhas, L.A. & Mubarik, A. Histological study of human sublingual gland with special emphasis on intercalated and striated ducts. (nature.com)
  • A simple gland has an unbranched duct (or no duct at all). (brainscape.com)
  • The cell of origin is believed to be the reserve cells in the intercalated duct system. (webpathology.com)
  • Recent work has detailed the anatomic and structural characteristics of the lacrimal duct system (Ding et al. (descarga.nu)
  • BACKGROUND: Distal renal tubular acidosis (dRTA) is a rare genetic disease caused by mutations in different genes involved in the secretion of H+ ions in the intercalated cells of the collecting duct. (ucy.ac.cy)
  • Striated and intercalated ducts are also present. (wikipedia.org)
  • SLC22A17 ) in inner medullary collecting duct (IMCD) cells, which are present in vivo in a hyperosmotic/-tonic environment that activates canonical Wnt/β-catenin signaling. (biomedcentral.com)
  • The duct passes close to the molar and incisor tooth roots and can therefore be affected by dental disease (Marini et al. (descarga.nu)
  • We found that β 3 is highly expressed in collecting duct of rodents, and that mineralocorticoids decreased the expression of β 3 . (pucv.cl)
  • A recent study has implicated Lcn2 secretion from collecting duct (CD) α-intercalated cells as a bacteriostatic defense mechanism against pathogenic bacteria in the urine [ 14 ]. (biomedcentral.com)