Interacts functional tyrosine kinase domain src homology 3 domain. Medical search. Frequent questions

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Anatomy17

Cell Line 3T3 Cells Cells, Cultured Tumor Cells, Cultured Cell Line, Tumor Cell Membrane COS Cells HeLa Cells Cytoplasm Jurkat Cells CHO Cells Cell Nucleus Fibroblasts Cell Line, Transformed NIH 3T3 Cells HEK293 Cells PC12 Cells

Organisms8

Escherichia coli Cercopithecus aethiops Cricetinae Saccharomyces cerevisiae Mice, Knockout Cattle Mice, Inbred C57BL Chickens

Diseases6

Pain Insensitivity, Congenital Cell Transformation, Neoplastic Hypohidrosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lung Neoplasms Carcinoma, Non-Small-Cell Lung

Chemicals and Drugs139

Tyrosine Protein-Tyrosine Kinases Receptor Protein-Tyrosine Kinases src-Family Kinases Phosphotyrosine Protein Kinase Inhibitors Receptor, Epidermal Growth Factor Proto-Oncogene Proteins Phosphatidylinositol 3-Kinases Recombinant Fusion Proteins Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-abl Protein Kinases Protein-Serine-Threonine Kinases Proto-Oncogene Proteins pp60(c-src)Adaptor Proteins, Signal Transducing Recombinant Proteins Phosphoproteins Pyrimidines Intracellular Signaling Peptides and Proteins fms-Like Tyrosine Kinase 3 Receptor, Insulin Protein Tyrosine Phosphatase, Non-Receptor Type 11 Calcium-Calmodulin-Dependent Protein Kinases Protein Tyrosine Phosphatase, Non-Receptor Type 6 Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)DNA, Complementary Benzamides DNA-Binding Proteins Proto-Oncogene Proteins c-kit Piperazines Enzyme Inhibitors DNA Primers Membrane Proteins RNA, Messenger GRB2 Adaptor Protein Carrier Proteins Janus Kinase 2 Proteins Quinazolines Proto-Oncogene Proteins c-ret Ligands Protein Kinase C DNA Receptor, trkA Receptors, Fibroblast Growth Factor Phospholipase C gamma Fusion Proteins, bcr-abl Proto-Oncogene Proteins c-met Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinases Epidermal Growth Factor Genistein Receptor, Fibroblast Growth Factor, Type 5 Focal Adhesion Protein-Tyrosine Kinases Antineoplastic Agents Focal Adhesion Kinase 2 Tyrosine 3-Monooxygenase Isoenzymes Transcription Factors SH2 Domain-Containing Protein Tyrosine Phosphatases Focal Adhesion Kinase 1 Mitogen-Activated Protein Kinase 3 Glutathione Transferase Receptors, Platelet-Derived Growth Factor Cyclic AMP-Dependent Protein Kinases Receptor, Fibroblast Growth Factor, Type 1 Drosophila Proteins Trans-Activators Peptide Fragments p38 Mitogen-Activated Protein Kinases Peptides Mitogen-Activated Protein Kinase Kinases Phosphotransferases (Alcohol Group Acceptor)Oncogene Protein pp60(v-src)Type C Phospholipases p21-Activated Kinases JNK Mitogen-Activated Protein Kinases Shc Signaling Adaptor Proteins Proto-Oncogene Proteins c-crk Nuclear Proteins Receptors, Cell Surface STAT5 Transcription Factor Milk Proteins Vanadates Serine Proto-Oncogene Proteins c-akt Calcium Phosphopeptides Proto-Oncogene Proteins c-hck Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase Kinases Receptors, Growth Factor Nerve Tissue Proteins Cytoskeletal Proteins Bacterial Proteins Receptors, Nerve Growth Factor Tyrphostins Enzyme Precursors Adaptor Proteins, Vesicular Transport Receptor, erbB-2 Proto-Oncogene Proteins c-cbl ZAP-70 Protein-Tyrosine Kinase Proline Protein Isoforms Phosphoric Monoester Hydrolases Ribosomal Protein S6 Kinases Quinones Cell Cycle Proteins Actins Oncogene Proteins Nerve Growth Factors Lactams, Macrocyclic Nucleoside-Phosphate Kinase Cyclin-Dependent Kinases Indoles Oncogene Proteins v-abl GTPase-Activating Proteins Benzoquinones CDC2 Protein Kinase Adenosine Triphosphate Guanylate Kinase Threonine Proto-Oncogene Proteins c-yes Macromolecular Substances MAP Kinase Kinase 1 Microfilament Proteins Receptor, IGF Type 1 RNA, Small Interfering eIF-2 Kinase Oncogene Proteins, Fusion Casein Kinase II Protein Tyrosine Phosphatase, Non-Receptor Type 1 Antibodies, Monoclonal Receptors, Antigen, B-Cell Cell Adhesion Molecules ras GTPase-Activating Proteins Receptors, Antigen, T-Cell

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Transfection Cloning, Molecular Sequence Alignment Mutagenesis, Site-Directed Models, Molecular Crystallography, X-Ray Blotting, Western DNA Mutational Analysis Precipitin Tests Immunoblotting Amino Acid Substitution Models, Biological Two-Hybrid System Techniques Polymerase Chain Reaction Electrophoresis, Polyacrylamide Gel Peptide Mapping Immunoprecipitation Microscopy, Fluorescence Immunohistochemistry

Phenomena and Processes63

src Homology Domains Phosphorylation Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid Mutation Protein Binding Base Sequence Protein Structure, Tertiary Binding Sites Enzyme Activation Transfection MAP Kinase Signaling System Protein Conformation Kinetics Structure-Activity Relationship Amino Acid Motifs Point Mutation Sequence Deletion Protein Interaction Domains and Motifs Dimerization Sequence Homology, Nucleic Acid Amino Acid Substitution Protein Structure, Secondary Cell Division Mutation, Missense Genes, erbB-1 Gene Expression Conserved Sequence Genes, src Protein Transport Substrate Specificity Exons Mutagenesis Transcription, Genetic Drug Resistance, Neoplasm Plasmids Apoptosis Gene Expression Regulation Phenotype Proto-Oncogenes Cell Adhesion Protein Processing, Post-Translational Time Factors Dose-Response Relationship, Drug Cell Movement Catalysis Molecular Weight Oncogenes Cell Proliferation Down-Regulation PDZ Domains Gene Expression Regulation, Enzymologic Structural Homology, Protein Protein Multimerization Catalytic Domain Cell Differentiation Transcriptional Activation Protein Structure, Quaternary Promoter Regions, Genetic Protein Folding Genes, abl Cell Survival

Disciplines and Occupations1

Immunohistochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Technology, Industry, Agriculture Information Science

src Homology Domains Tyrosine Protein-Tyrosine Kinases Phosphorylation Receptor Protein-Tyrosine Kinases Molecular Sequence Data Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid src-Family Kinases Mutation Phosphotyrosine Protein Kinase Inhibitors Protein Binding Receptor, Epidermal Growth Factor Base Sequence Proto-Oncogene Proteins Phosphatidylinositol 3-Kinases Protein Structure, Tertiary Recombinant Fusion Proteins Binding Sites Enzyme Activation Cell Line Transfection Cloning, Molecular Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-abl Protein Kinases Protein-Serine-Threonine Kinases Proto-Oncogene Proteins pp60(c-src)Adaptor Proteins, Signal Transducing Recombinant Proteins Phosphoproteins Sequence Alignment 3T3 Cells MAP Kinase Signaling System Mutagenesis, Site-Directed Pyrimidines Intracellular Signaling Peptides and Proteins Models, Molecular fms-Like Tyrosine Kinase 3 Receptor, Insulin Protein Conformation Protein Tyrosine Phosphatase, Non-Receptor Type 11 Kinetics Calcium-Calmodulin-Dependent Protein Kinases Crystallography, X-Ray Cells, Cultured Protein Tyrosine Phosphatase, Non-Receptor Type 6 Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Structure-Activity Relationship DNA, Complementary Benzamides DNA-Binding Proteins Amino Acid Motifs Point Mutation Sequence Deletion Proto-Oncogene Proteins c-kit Protein Interaction Domains and Motifs Piperazines Enzyme Inhibitors DNA Primers Membrane Proteins Dimerization Blotting, Western RNA, Messenger GRB2 Adaptor Protein DNA Mutational Analysis Pain Insensitivity, Congenital Carrier Proteins Precipitin Tests Janus Kinase 2 Proteins Sequence Homology, Nucleic Acid Quinazolines Proto-Oncogene Proteins c-ret Ligands Immunoblotting Tumor Cells, Cultured Cell Line, Tumor Protein Kinase C Amino Acid Substitution DNA Receptor, trkA Protein Structure, Secondary Receptors, Fibroblast Growth Factor Phospholipase C gamma Fusion Proteins, bcr-abl Cell Membrane Proto-Oncogene Proteins c-met Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinases Cell Division COS Cells Epidermal Growth Factor Cell Transformation, Neoplastic Genistein Receptor, Fibroblast Growth Factor, Type 5 Hypohidrosis

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