• BioGRID interactions are binary relationships between two proteins or genes. (google.com)
  • Physical interactions are defined as the direct physical binding of two proteins, or co-existence in a stable complex, whereas genetic interactions are interactions between two or more mutants. (google.com)
  • By bringing these together this session will provide a sound platform to define the parameters and complete 'interaction space' of how peptides (and proteins) interact with lipid bilayers. (rsc.org)
  • Such interactions play a vital role in cellular processes, therefore studying networks of interacting proteins can give fundamental biological insights. (news-medical.net)
  • Protein interaction networks can be created using protein interactions determined by any single or a combination of multiple experimental methods and data sets, where each protein is represented by a node, and two proteins are linked with each other if they have been shown to interact. (news-medical.net)
  • The yeast two-hybrid system (originally published in 1989) permits the profiling of protein interactions of any two proteins, which may be scaled up to cover the whole proteome of an organism. (news-medical.net)
  • New research from the Buck Institute in California offers insights into new treatments targeting the interaction between ApoE4 and SirT1 proteins, moving closer to developing preventative treatments for Alzheimer's among people genetically predisposed to the disease. (medicalnewstoday.com)
  • Serum binding proteins and steroid-immunoglobulin interaction are also discussed, along with the relationship of these binding processes to the biological action of the steroid. (worldcat.org)
  • Interactions between proteins modulate a large number of biological processes-from fleeting interactions during the transduction of a signaling pathway to the assembly of large multiprotein complexes. (promega.com)
  • The extreme brightness and small size of NanoLuc® Luciferase make it possible to label proteins with less risk of interfering with natural function, and allow detection of interactions in vivo under natural conditions. (promega.com)
  • Interaction of the target proteins facilitates subunit complementation to give a bright, luminescent enzyme. (promega.com)
  • Some experimental protocols, such as tandem affinity purification (TAP) , generate complex data sets, depicting interactions in which more than two proteins are involved at the same time (n-ary interactions). (ebi.ac.uk)
  • T.A. Schroer and S.R. Gill , Interactions between Microtubules and Intracellular Membranes: The Roles of Microtubule-Based Motors and Accessory Proteins. (elsevier.com)
  • A.S. Fanning, L.A. Lapierre, A.R. Brecher, and C.M. Van Italie , Protein Interactions in the Tight Junction: The Role of MAGUK Proteins in Regulating Tight Junction Organization and Function. (elsevier.com)
  • These proteins form oligomeric structures and share a conserved α -crystallin domain responsible for intersubunit β -strand- β -strand interactions in the basic dimer subunit. (hindawi.com)
  • However, the mechanism of the interaction between Hsp27 and actin is unclear and controversial and a binding study of the interaction between the two proteins in vitro has not been reported [ 3 ]. (hindawi.com)
  • Since that study it has generally been assumed that Hsp25 and Hsp27 are actin barbed-end-capping proteins, although there has been little further support for this interaction model. (hindawi.com)
  • Proteins matching this entry have been experimentally proven to be involved in Protein:Protein interactions. (ebi.ac.uk)
  • Many of these helicases are constituents of multicomponent assemblies, and their interactions with partner proteins within the complexes underpin their activities and biological function. (mendeley.com)
  • The Plant Biotic Interactions (PBI) program supports research on the processes that mediate beneficial and antagonistic interactions between plants and their viral, bacterial, oomycete, fungal, plant, and invertebrate symbionts, pathogens and pests. (nsf.gov)
  • The program's scope extends from fundamental mechanisms to translational efforts, with the latter seeking to put into agricultural practice insights gained from basic research on the mechanisms that govern plant biotic interactions. (nsf.gov)
  • This course will show you what kind of information you can find in IntAct (one of the EBI's molecular interactions databases), how to access it, the different tools that can be used to access data and some practical examples on how to search and. (ebi.ac.uk)
  • When beginning a new prescription to treat your arthritis or related condition, you should always discuss potential food and beverage interactions with your doctor or pharmacist. (arthritis.org)
  • Because of the amount of time a particular drug stays in your body and due to its interaction with another drug you are taking, a pharmacist may advise you to take each drug at different times of the day. (fda.gov)
  • Many drug interactions occur because of the way they are metabolized in the liver, said Lois Parker, senior pharmacist at Massachusetts General Hospital. (cnn.com)
  • Older adults can prevent adverse drug interactions by reducing the number of medications they take, communicating with their physician or pharmacist and making other lifestyle changes, advises Don Brindisi, pharmacy manager at Masonic Village. (prweb.com)
  • However, they should tell their primary care physician and pharmacist, since these can cause adverse drug interactions. (prweb.com)
  • If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. (rxlist.com)
  • Current human-computer interaction models assume there is a single user, engaging with full attention on a single computer system. (microsoft.com)
  • In addition, neutrinos may interact with hadrons as well, since hadrons participate in the weak interaction (e.g. beta decay is a weak interaction). (physicsforums.com)
  • All types of neutrinos may interact with electrons through weak interactions via the exchange of a Z boson. (physicsforums.com)
  • A clearer understanding of how chemical characteristics of woody plants interact with herbivores presents an opportunity (1) for improving herbivore productivity and (2) to guide future modeling of browse-browser interactions in rangelands dominated by chemically defended encroaching woody plants. (wur.nl)
  • At Cornell we study them all: designing ways people interact with computing systems, ways computers mediate communication and other interaction between people, things we can learn about people by looking at those interactions, and impacts of computing on society in a number of critical domains from education to health. (cornell.edu)
  • Interactions between herbivores (vertebrate and invertebrate) and plants drive energy/nutrient exchange and biodiversity. (edu.au)
  • Overall, the program seeks to support research that will deepen our understanding of the fundamental processes that mediate interactions between plants and the organisms with which they intimately associate and advance the application of that knowledge to benefit agriculture. (nsf.gov)
  • Steroid-Cell Interactions describes the processes involved in the intracellular binding of steroids (and related compounds) in mammalian cells. (worldcat.org)
  • More specifically, Dr. Carlyle-Moses' research aims to better understand the biotic and abiotic mechanisms that govern precipitation partitioning by vegetation canopies, to evaluate and improve upon models used to simulate these water stores and fluxes, and to determine the linkages between plant-water interactions and terrestrial hydrological processes. (springer.com)
  • We examine the ecological interactions between various life forms, from microorganisms in the soil to large mammals, and relate these to ecosystem processes and services. (wsl.ch)
  • Cholinergic-Monoaminergic Interactions in the Brain investigates dynamic synaptic mechanisms in the brain and their links to various behaviors and related functional processes. (elsevier.com)
  • Organized into six sections comprised of 18 chapters, this volume begins with an overview of various models of cholinergic-monoaminergic and other chemical interactions, based in part on interactive processes that are believed to operate in the peripheral nervous system. (elsevier.com)
  • Finally, the book assesses the significance of central cholinergic-monoaminergic interactions for functional processes, both normal and pathologic. (elsevier.com)
  • Hsp27 has been implicated in numerous physiological and pathological processes that involve its interaction with actin and its control of actin dynamics [ 11 - 25 ]. (hindawi.com)
  • Electrons accelerated onto a material result in a number of interactions with the atoms of the target sample. (carleton.edu)
  • In the context of binding protons and neutrons together to form atoms, the strong interaction is called the nuclear force (or residual strong force ). (wikiversity.org)
  • You can reduce the risk of harmful drug interactions and side effects by understanding the drugs that you take. (fda.gov)
  • Alcohol often has harmful interactions with prescription medications , over-the-counter drugs, and even some herbal remedies. (webmd.com)
  • In other cases, alcohol interactions may make drugs harmful or even toxic to the body. (webmd.com)
  • In recent years, an increased consumption of herbal medicines worldwide has increased the need to understand potential interactions between these compounds and traditional drugs, especially those with a narrow therapeutic window, such as CyA. (hindawi.com)
  • (CNN) -- As friends of pop star Michael Jackson discuss the role prescription drugs may have played in his Thursday death, the serious health problems that can be triggered by drug interactions are again in the spotlight. (cnn.com)
  • The Food and Drug Administration highlights several interactions between drugs and various substances on its Web site . (cnn.com)
  • You can go to www.drugs.com and use their drug interactions checker. (dailystrength.org)
  • I don't know of drug interactions with over the counter drugs. (dailystrength.org)
  • The reader is also introduced to the effects of lesion in the globus pallidus, the electrophysiology of interactions, the effects of drugs thought to preferentially affect monoaminergic or related neurotransmission mechanisms on acetylcholine in the brain, and whether dopamine is excitatory or inhibitory upon neostriatal neurons. (elsevier.com)
  • Since seniors are often taking larger quantities of drugs, they have an increased risk of many CYP450 interactions, whether it's inhibiting or enhancing the enzyme's effects," Brindisi said. (prweb.com)
  • Older adults can reduce their risk of CYP450 interactions by cutting back the amount of drugs they take. (prweb.com)
  • Proteomics based on quantitative mass spectrometry combined with affinity purification protocols has become the method of choice to map and follow the dynamic changes in protein-protein interactions - including the ones occurring during cellular signaling events. (news-medical.net)
  • BioGRID is a repository of interaction data manually curated from scientific literature for Saccharomyces cerevisiae as well as other organisms. (google.com)
  • Her research is extremely complex, requiring knowledge of arthropods and plants and the interaction between the two groups of organisms. (amnh.org)
  • In ecology , a biological interaction is the effect that a pair of organisms living together in a community have on each other. (wikipedia.org)
  • A thorough analysis of such networks can also aid in assessing the drug ability of molecular targets from network topology, delineating frequent interaction network motifs, drawing comparisons between model organisms and human, and also estimating interactions reliability. (news-medical.net)
  • A greater understanding of such nutrient: gene interactions should lead to improved nutritional advice and pharmacological interventions to maintain lifelong health and prevent, or delay the onset of, chronic diseases commonly associated with the aging process. (nottingham.ac.uk)
  • We research the ecological interactions between various life forms, from microorganisms in the soil, to plants, insects and large mammals, and relate these to ecosystem services such as productivity, stability, nutrient cycles and nutrient storage. (wsl.ch)
  • With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts. (wiley-vch.de)
  • The situated interaction research effort aims to enable computers to reason more deeply about their surroundings, and engage in fluid interaction with humans in physically situated settings. (microsoft.com)
  • Our research aims to address these challenges and create the basis for a new generation of situated systems that are capable of fluid interactions and collaborations with people. (microsoft.com)
  • The project aims at understanding the milti-trophic interactions between different ash genotypes, ADB, EAB and its natural enemies under different climatic conditions. (wsl.ch)
  • The discussion then turns to the neurohistochemical and neurobiochemical aspects of cholinergic-monoaminergic interactions, the effects on neostriatal acetylcholine levels, and the synthesis of the cortico-neostriatal and thalamo-neostriatal pathways. (elsevier.com)
  • Demerol can have serious interactions with the class of antidepressants known as MAO inhibitors, with effects ranging from increased heart rate and higher blood pressure to cardiac arrest. (cnn.com)
  • The "Chemical Interactions" society provides all Departmental members (undergraduates, postgraduates and all staff) with opportunities to get to know other people working and studying in Chemistry at York through informal and social events. (york.ac.uk)
  • Chemical Interactions holds a range of events including quiz nights, careers talks, networking events, cake sales, picnics and Christmas parties. (york.ac.uk)
  • Email [email protected] for more information or if you would like to join Chemical Interactions. (york.ac.uk)
  • Recent advances in our understanding of light-matter interactions, often with patterned and resonant structures, reveal nascent concepts for new interactions that may impact many applications. (darpa.mil)
  • Insights regarding the origins of these interactions have the potential to transform our understanding of how to control electromagnetic waves and design for new light-matter interactions. (darpa.mil)
  • These models will provide design tools and delineate the performance limits of new engineered light-matter interactions. (darpa.mil)
  • In addition to providing new knowledge of nanoscale light-matter interactions, our studies will propel future reconfigurable and self-responsive material applications. (anl.gov)
  • Every time you use a drug, take the time to learn about possible drug interactions and read the drug label. (fda.gov)
  • Possible drug interactions can include serotonin syndrome, a potentially fatal condition that causes high levels of the chemical serotonin to accumulate in your body, heart disease due to impaired efficacy of blood pressure medications, or unplanned pregnancy due to contraceptive failure," Taylor said. (psychcentral.com)
  • Healthy Interactions' patient-centric, high-tech platform (the MyHealthMap™ platform) links with 93 devices (i.e., weigh scales, blood glucose monitors and blood pressure monitors) and connects patients with licensed healthcare professionals for ongoing support. (prweb.com)
  • The high-touch solution is enabled by Healthy Interactions' nationwide-network of over 10,000 licensed healthcare professional educators. (prweb.com)
  • Our digital tools empower healthcare consumers to move toward their goals by providing information, tracking, and ongoing interactions with peers and health educators. (prweb.com)
  • Being prescribed medications from multiple healthcare providers - especially those working independently of each other - is likely to lead to drug interactions," Brindisi said. (prweb.com)
  • In order to address some of these issues we have investigated the interaction between Hsp27 and actin, in vitro , using fluorescence probes attached to Hsp27. (hindawi.com)
  • The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. (webmd.com)
  • X. Yao and J.G. Forte , Membrane-Cytoskeleton Interaction in Regulated Exocytosis and Apical Insertion of Vesicles in Epithelial Cells. (elsevier.com)
  • Taylor-Smith, L.M. Cryptococcus -Epithelial Interactions. (mdpi.com)
  • A global leader in health education, Healthy Interactions, creates powerful educational approaches that inspire valuable insights and change personal health behaviors. (prweb.com)
  • Because oseltamivir and oseltamivir carboxylate are excreted in the urine by glomerular filtration and tubular secretion via the anionic pathway, a potential exists for interaction with other agents excreted by this pathway. (cdc.gov)
  • The low potential for drug interactions with zanamivir. (cdc.gov)
  • The energy of the incident beam (accelerating potential) increases the interaction volume, but decreases the elastic scattering (e.g. backscattering). (carleton.edu)
  • Using its collective voice and convening power, InterAction seeks to shape important policy decisions and actions across a wide range of issues - including foreign assistance, humanitarian relief, development, economic equity, food security, and climate change - that advance human dignity, human potential, and self-determination. (idealist.org)
  • The package insert provides more information about potential OTC and prescription drug interactions. (fda.gov)
  • An overview of current approaches, their advantages and disadvantages, is given and the promising potential of pharmacologically interfering with protein-glycan interactions is highlighted here. (nih.gov)
  • Accessibility measures the potential of opportunities for interaction. (repec.org)
  • Potential regulatory interactions. (mendeley.com)
  • Earlier studies have identified the regulator of ribonuclease activity A (RraA) as a potential interaction partner of both RNase E and RhlB. (mendeley.com)
  • Similarly, there are many experimental tools to measure the interactions of macromolecules with membranes to a high degree of accuracy. (rsc.org)
  • A paramount challenge in analyzing the large data sets is in the distinction of true protein interactions from the experimental noise that exists in the raw data obtained by a large-scale screening method. (news-medical.net)
  • The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. (wiley-vch.de)
  • The next chapters focus on experimental observations on electrophysiologic and neurochemical interactions in the brain and the functional correlates of such interactions. (elsevier.com)
  • Some dietary supplements can cause interactions with prescription and over-the-counter medicines. (familydoctor.org)
  • The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (drugs.com)
  • Does Pradaxa have food interactions like coumadin, & any effects on phosphorous or creatinine? (drugs.com)
  • With recent advances in computational modelling, it is now feasible to model membranes that can deliver realistic representations of multi-lipid assemblies and the interactions of peptides with these structures with atomistic detail seems also within reach. (rsc.org)
  • Regulation food intake and energy expendiuture (funded by BBSRC )- Interaction between nutrients and specific peptides in hypothalamic regulation of food intake and energy expenditure. (nottingham.ac.uk)
  • In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. (biomedcentral.com)