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  • pore
  • The phenomenon of inward rectification of K ir channels is the result of high-affinity block by endogenous polyamines , namely spermine , as well as magnesium ions, that plug the channel pore at positive potentials, resulting in a decrease in outward currents. (wikipedia.org)
  • neuronal
  • Despite their potential importance in neuronal function, direct experimental evidence on electrical signaling in dendritic spines is lacking as their small size makes them inaccessible to standard electrophysiological techniques. (jneurosci.org)
  • molecular
  • From the interplay of high-resolution scanning tunneling microscopy (STM) imaging/manipulation and density functional theory (DFT) calculations, we have shown that the spontaneous formation of an organometallic complex by copper-alkene interactions can be successfully achieved, where the specific molecular adsorption geometry is revealed to be the key for facilitating such interaction. (jove.com)
  • First, we show that the continuum method accurately reproduces energy profiles and membrane shapes generated from molecular simulations of bare ion permeation at a fraction of the computational cost. (springer.com)
  • conclude
  • We conclude that plants with a wide array of pollinator interactions tend to be those that are more strongly dependent upon them for seed production and thus might be those more functionally vulnerable to the loss of network interaction, although these outcomes might be context-dependent. (jove.com)
  • Biology
  • Choice of cooperative agreement is based on the need for NIH staff involvement in interactions among the many components of the PSI:Biology network to be established. (nih.gov)
  • viral
  • This work strongly argues for a conserved mechanism of exocytosis for both particles and sets the stage for examining the role of glycosylation in trafficking of proteins to the sites of microvesicular and viral budding. (utexas.edu)
  • nonlinear
  • chess downloads Membrane has thought to the Paleopathology of nonlinear experiments request for the magnetic singularity of fibrous Positive waves rhetorical as various plays and more 27(2 remains and arts. (chessaid.com)
  • limits
  • Venovenous extracorporeal membrane oxygenation is an effective adjunctive therapy and can be used as a life-saving procedure for carefully selected patients with severe acute respiratory distress syndrome when the limits of standard therapy have been reached. (hkmj.org)
  • depend
  • Information on the extent to which plants depend on such interactions will help to make more realistic predictions of the potential impacts of disturbances on plant-pollinator networks. (jove.com)
  • evaluate
  • Aim: To evaluate the potential of newly-developed, biocompatible iron oxide magnetic nanoparticles (MNPs) conjugated with J591, an antibody to an extracellular epitope of PSMA, to enhance MRI of prostate cancer. (jove.com)
  • test your chess skills It affects In Communicative to obtain and be Traditions in important acoustic parabolic dynamics to evaluate an distal Membrane for a very produced gravity of the propagation. (chessaid.com)
  • mechanism
  • Campelo F, McMahon HT, Kozlov MM (2008) The hydrophobic insertion mechanism of membrane curvature generation by proteins. (springer.com)
  • frequency
  • Studies on pollination networks have provided valuable information on the number, frequency, distribution and identity of interactions between plants and pollinators. (jove.com)
  • conventional
  • Venovenous extracorporeal membrane oxygenation (ECMO) has become a reliable respiratory support for patients with severe respiratory failure due to acute respiratory distress syndrome and severe hypoxaemia despite the use of conventional therapy. (hkmj.org)
  • In 2009, the conventional ventilatory support versus extracorporeal membrane oxygenation (ECMO) for severe adult respiratory failure (CESAR) trial, conducted by Peek et al 3 in the UK, showed a significant survival advantage with the use of ECMO for patients with severe ARDS. (hkmj.org)
  • genetic
  • We have tested for genetic interactions between mutant alleles causing deficiency in OCA2 (pink-eyed dilution unstable), AP-3 (pearl), BLOC-1 (pallid), and BLOC-2 (cocoa) in C57BL/6J mice. (wiley.com)
  • functional
  • However, little is still known on the functional effect of these interactions on plant reproductive success. (jove.com)
  • Plant functional dependence on pollinators (all interactions pooled) can be estimated by comparing seed set with and without pollinators (i.e. bagging flowers to exclude them). (jove.com)
  • The mountain community, by contrast, did not show such functional relationship, what might be attributable to their lower flower-resource heterogeneity and diversity of interactions. (jove.com)
  • experiments
  • We studied the effects of changing the pyloric cycle period on this reciprocally inhibitory subnetwork in three sets of experiments. (jneurosci.org)
  • network
  • Phylogenetically controlled regression analyses revealed that, for the largest and most diverse coastal community, plants highly dependent on pollinators were the most generalists showing the highest number and diversity of interactions as well as occupying central positions in the network. (jove.com)
  • differ
  • Although they do not differ between outpatient and inpatient settings, new hazardous coprescriptions are more frequently generated in hospital. (springeropen.com)
  • action
  • Backpropagating action potentials were found to fully invade dendritic spines without voltage loss. (jneurosci.org)
  • The higher potency of R (+)-bupivacaine to block the inactivated state of the cardiac Na + channel may explain its higher toxicity because of the large contribution of the inactivated-state block during the plateau phase of the cardiac action potential. (ahajournals.org)
  • immune
  • hence the incorporation of microvesicular proteins could influence interactions of HIV with the immune system. (utexas.edu)
  • Exosomes are a potential source of self-antigen for modulating the immune response against self-tissues, including tumors. (bloodjournal.org)
  • although
  • Both enantiomers also bind with high affinity to the activated or open state of the channel, but this interaction did not display stereoselectivity, although the binding to the activated or open state was faster for S (−)- than for R (+)-bupivacaine. (ahajournals.org)
  • similar
  • The exposure to all potential statin-drug interactions was similar at hospital admission (26.1%) and discharge (24.4%), as was the exposure to statin combinations with CYP inhibitors, 6.4% and 4%, correspondingly. (springeropen.com)