Interact with other proteins function carrier proteins. Medical search. Frequent questions

G protein-coupled receptors (GPCRs) are, with approximately 800 members, among the most abundant membrane proteins in humans. (nih.gov)
Along their life cycle, GPCRs are accompanied by a range of specialized GPCR-interacting proteins (GIPs) to assist nascent receptors in proper folding, to target them to the appropriate subcellular compartments and to fulfill their signaling tasks. (nih.gov)
Watkins (2019) reported that CBD interacts with various chemicals, proteins, and receptors in the human brain. (boutiquetoyou.com)
In vitro and in vivo experiments will be conducted to investigate how recombinant transferrin interacts with cellular receptors, regulates iron uptake, and influences cellular proliferation. (prospecbio.com)
The coronavirus spike (S) glycoprotein is a class I viral fusion protein on the outer envelope of the virion that plays a critical role in viral infection by recognizing host cell receptors and mediating fusion of the viral and cellular membranes. (biolegend.com)
It is believed that FT4 could cross cell membranes and interacts with receptors [ 2 ], showing metabolically active and clinically relevant effect. (ijbs.com)
Membrane receptors are specialized protein molecules attached to or integrated into the cell membrane. (rhumbarlv.com)
Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal signaling pathways. (rhumbarlv.com)
Receptors are a special class of proteins that function by binding a specific ligand molecule. (rhumbarlv.com)
The LDL receptor and transferrin receptors are examples of receptors that function by receptor-mediated endocytosis. (rhumbarlv.com)
membrane receptors are specialized protein molecules in the membranes of cells, to which external molecules (hormones, neurotransmitters, drugs) attach, triggering changes in the function of the cell. (rhumbarlv.com)
Hundreds of different G-protein-linked receptors have been identified. (rhumbarlv.com)

Pigment cell-specific transmembrane proteins SLC45A2 and OCA2 are a transporter and channel, respectively, that modulate melanosome pH at different stages of melanosome maturation and that are targets of mutation in different forms of oculocutaneous albinism. (chop.edu)
Cells use special transmembrane proteins which carry small water-soluble organic molecules to navigate through the bilayer. (microbiologynotes.org)

Secretory carrier-associated membrane protein 1 is a protein that in humans is encoded by the SCAMP1 gene. (wikipedia.org)
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. (phys.org)
the team and its collaborators have shown that the products of HPS-associated genes in skin melanocytes regulate two pathways of membrane protein transport from endosomes to newly forming melanosomes and a retrograde pathway from melanosomes. (chop.edu)
To mediate transfer of polar molecules which includes ions, sugar, amino acids across the bilayer, perform by transporters, a specialized membrane protein. (microbiologynotes.org)
Which is not a function of a membrane protein? (rhumbarlv.com)
Four types of membrane proteins are Integral Membrane Protein, Peripheral Membrane Protein, Transmembrane Protein, and Integral Monotopic Proteins. (rhumbarlv.com)

Proteins in lipid membranes are one of the fundamental building blocks of biological functionality. (phys.org)
More than half of all proteins interact with membranes. (phys.org)
Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. (phys.org)
To do their work, APTs have to interact with the lipid membranes that their target proteins are bound to. (epfl.ch)
Finally, the scientists brought their data together to work out how APT2 actually binds lipid membranes, which is essential to its capacity to perform its function in the cell. (epfl.ch)
This study shows that APT2 is in fact a hybride between a lipid carrier protein, which can extract lipid from membranes, and a hydrolase, which can cut the lipid of a protein," says Gisou van der Goot. (epfl.ch)
The lab employs a variety of approaches to probe how BLOC-1 interacts with membranes and with other HPS-encoded protein complexes to better understand its mechanism of action. (chop.edu)
Cells have evolved the mechanisms to carry water-soluble molecules and ions across the membranes to perform essential functions like ingesting essential nutrients, excreting metabolic waste products, and regulating intracellular ion concentrations. (microbiologynotes.org)
Membrane proteins are common proteins that are part of, or interact with, biological membranes. (rhumbarlv.com)

Ultimately, we sought to identify the physiological function of the liver-specific mitochondrial carrier Slc25a47 in liver lipid metabolism and energy expenditure. (wur.nl)
Thus ANTs and the OXPHOS machinery physically interact and functionally cooperate to enhance ANT transport capacity and mitochondrial respiration. (elsevierpure.com)
TSPO is a ubiquitous mitochondrial protein and is involved in numerous biological functions. (uni-regensburg.de)
In the majority of cases, Rf genes produce proteins that act directly on the CMS conferring mitochondrial transcripts by binding them specifically and promoting processing events. (frontiersin.org)
These unusual ORFs are maternally inherited, and effectively translated into novel mitochondrial proteins, with the resulting failure to produce functional pollen as the sole observed phenotype ( Chen and Liu, 2014 ). (frontiersin.org)
In the majority of cases, Rf genes produce proteins that bind specifically to the CMS conferring transcripts in the mitochondria and promote processing events leading to a strong reduction in the production of mitochondrial CMS-inducing proteins (reviewed in Chen and Liu, 2014 ). (frontiersin.org)
Biological Function Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. (qedbio.com)

Because of their reactive nature, ionic gold species can interact with proteins, DNA and other biomolecules and disturb a series of cellular processes, leading to serious health problems. (iyte.edu.tr)
These vesicles are carriers of active or non-autonomous function biomolecules, such as proteins, lipids, DNA, mRNA and non-coding regulatory RNA. (spandidos-publications.com)

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. (wikipedia.org)
In humans, the CRYAA gene encodes a 173 amino acid residue protein by single copy genes located on chromosome 21. (molvis.org)
This includes gene, protein and metabolic networks, cellular architecture and intracellular dynamics, cell communication and motility, cell division and differentiation, tissue formation and organogenesis, tissue and organ functions, changes in population characteristics as a consequence of interaction of organisms with their physical environment, with individuals of their own species, and with organisms of other species. (nih.gov)
In addition, gold nanoparticles function as carriers for drugs and gene delivery systems. (iyte.edu.tr)
High density arrays of extraordinarily sensitive integrated microring resonators will allow many gene and protein signatures to be simultaneously quantitated from a single patient sample. (nih.gov)
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. (cancerindex.org)
What does this gene/protein do? (cancerindex.org)
After data processing and outlier removal, a total of 8,619 proteins were used to build a protein co-expression network using the weighted gene co-expression network analysis (WGCNA) algorithm 17 (Fig. 1b , Extended Data Fig. 1 and Supplementary Tables 2 - 4 ). (emtherapro.com)
These bioregulators act as mediators at the cellular level, orchestrating gene expression and protein synthesis. (peptidesforresearch.com)
This interaction governs the spatial conformation of DNA, regulates gene expression, and instigates protein synthesis. (peptidesforresearch.com)
In the years 2007 and 2008, when gene testing was restricted to BRCA1 and BRCA2 several studies have demonstrated that BRCA1 -mutation carriers are more likely to be diagnosed with TNBC than non-carriers [ 6 ]. (biomedcentral.com)
Overview of Genetics A gene, the basic unit of heredity, is a segment of DNA containing all the information necessary to synthesize a polypeptide (protein) or a functional RNA molecule. (msdmanuals.com)

CRYAA interacted with these proteins to maintain their solubility and decrease the accumulation of denatured target proteins. (molvis.org)

Membrane receptor proteins serve as connection between the cell's internal and external environments. (phys.org)
What is the function of receptor proteins in the cell membrane? (rhumbarlv.com)
What are receptor proteins simple definition? (rhumbarlv.com)
How are receptor proteins located in the cell membrane? (rhumbarlv.com)
What are receptor proteins examples? (rhumbarlv.com)

Combining structural biology, molecular simulations, mutagenesis, and in vivo assays, EPFL scientists have made the first extensive study of the mode of action of the enzyme acyl thioesterase, which regulates deacylation, one of the most critical functions of the cell. (epfl.ch)
It is an important process of the cell that regulates the localization and function of numerous proteins. (epfl.ch)

Our studies now show that the B-casein molecule has a specific shape and this shape determines its calcium carrying function and its ability to interact with other caseins in milk. (usda.gov)
Our results not only show clearly how B-casein molecule functions as an effective calcium carrier, but also suggest that portions of the molecule could be prepared and used as nutritional additives to transport other vital minerals. (usda.gov)
Area B will provide information on the structure and function of the TSPO molecule in response to TSPO ligands and within its multimeric complex by biophysical methods in order to unravel further molecular mechanisms of TSPO signaling and to give further input for TSPO ligand drug development. (uni-regensburg.de)
In this thesis, total internal fluorescence microscopy (TIRF) and single-molecule imaging were used to observe and characterize protein-functionalized supported lipid bilayers (SLBs) interacting with immune cells to obtain the binding kinetics of various protein-protein pairs. (lu.se)

Previous theories proposed that B-casein had a random or 'spaghetti'-like shape and as a result, interactions with other milk proteins were also nonspecific. (usda.gov)
To identify proteins interacting with alpha A-crystallin (CRYAA) and to investigate the potential role that these protein interactions play in the function of CRYAA using a human proteome (HuProt) microarray. (molvis.org)
A HuProt microarray composed of 17,225 human full-length proteins with N-terminal glutathione S-transferase (GST) tags was used to identify protein-protein interactions. (molvis.org)
The protein-protein interactions may help CRYAA carry out multifaceted functions. (molvis.org)
To understand the functions of CRYAA and how these are regulated, protein-protein interactions need to be investigated. (molvis.org)
These interactions may lead to changes in the bioavailability of proteins and other (phyto) nutrients. (fcshenxianhu.com)
It also refers as " Extrinsic proteins " that associates with the lipid bilayer by weak electrostatic and hydrogen bond interactions. (rhumbarlv.com)
Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. (lu.se)

Analogous to its yeast counterpart, human ANTs associate with heterologous partner proteins, including the respiratory supercomplex (RSC) and other solute carriers. (elsevierpure.com)
The barrier function of lipid bilayer permits maintenance of concentrations of solute in its cytosol which differ from the extracellular environment. (microbiologynotes.org)
The transporters are also named as carriers or permeases , it functions by interacting with specific solute, and experience chain of conformational changes for the transfer of bound solute to cross the bilayer. (microbiologynotes.org)

Furthermore, their biogenesis, composition and function have been associated with viruses, an entirely different domain of life. (spandidos-publications.com)

The devices and kits include one or more associators specific for molecular targets, such as microRNAs and proteins and peptide fragments thereof. (justia.com)
3. Chimerical peptides according to the claim 1, characterized by containing a segment inhibitor of the activation of the NS3pro protease, this segment is a peptide able to bind to NS3pro and contact at least one residue comprised in the region Gly21-Lys28 of the N-terminal domain of the NS3pro protein from DV2 or structurally equivalent residues of the NS3pro protein from other Flavivirus. (patentsencyclopedia.com)
Peptide bioregulators are remarkable information carriers characterized by their unique sequences of amino acids. (peptidesforresearch.com)
In theory, peptides may inhibit the function of DNA methyltransferases, thus offering a potential mechanism for peptide-mediated transcription regulation. (peptidesforresearch.com)

The unique biological functions of milk proteins arise directly from their three-dimensional shape, which in turn determines the properties of products made from them. (usda.gov)
It has a molecular mass of 777 Dalton and is involved in regulating many biological functions, such as oxygen consumption, growth, development and protein synthesis. (ijbs.com)

Exosomal markers include microRNAs like miR-21 and miR-141, plus various proteins that belong in functional groups such as tetraspanins (CD9, CD63 and CD81), heat shock proteins (Hsp70, Hsp73 and Hsp90) and membrane transporters (GTPases) ( 4 ). (spandidos-publications.com)
Membrane transport is carried out by two major classes of protein - Transporters and channels . (microbiologynotes.org)

Background HspA9, a memer of the Hsp70 family, encodes a heat-shock cognate protein that is involved in the control of cell proliferation and acts as a chaperone. (qedbio.com)

Lipid bilayer permits hydrophobic molecules to cross the membrane, which includes steroids hormones, gases only O 2 and CO 2 , small polar uncharged molecules like ethanol and H 2 O, by the means of passive diffusion, whereas charged molecules of any size which includes amino acids and small ions such as H + , Na + , K + , Ca + requires membrane proteins to perform the transport. (microbiologynotes.org)

3.0: hematopoietic cell-specific Lyn substrate 1 (HCLS1), Kelch domain-containing 6 (KLHDC6), sarcoglycan delta (SGCD), KIAA1706 protein (KIAA1706), RNA guanylyltransferase and 5′-phosphatase (RNGTT), chromosome 10 open reading frame 57 (C10orf57), chromosome 9 open reading frame 52 (C9orf52), and plasminogen activator, urokinase receptor (PLAUR). (molvis.org)

Exosomes are one of the most researched classes of extracellular vesicles because they are carriers of targeted protein and DNA/RNA loads. (spandidos-publications.com)
In the poster section, Joanna Shisler (University of Illinois at Urbana-Champaign [UIUC], Urbana) reported that the modified virus, Ankara, activates nuclear factor κB through the mitogen-activated protein kinase, extracellular signal-regulated kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway, possibly facilitating the host immune response. (cdc.gov)

It is likely that CORVET conducts a similar function at endosomes because Vps33 also has the ability to interact with the endosomal syntaxin-like Pep12 protein Subramanian et al. (tradegenix.net)
These short chains of amino acids, with their unique ability to interact with specific DNA segments, promise to unlock the secrets to cellular regeneration, optimal functioning, and even the quest for prolonged youthfulness. (peptidesforresearch.com)

They function as carriers to the cell surface in post-golgi recycling pathways. (wikipedia.org)
These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. (wikipedia.org)
However, the ultimate biological effectors of AD genetic and environmental risk are often the proteins and the metabolic pathways they modulate. (emtherapro.com)
In Plasmodium, the endoplasmic reticulum (ER) is a central hub for protein folding and trafficking as well as stress response pathways. (cdc.gov)

Protein synthesis, folding. (msdmanuals.com)

In most gram-positive bacteria, this operon consists of five genes dltXABCD but the involvement of the first ORF ( dltX ) encoding a small protein of unknown function, has never been investigated. (frontiersin.org)
A comprehensive understanding of the physiological and molecular function of PPARα target genes is needed for the accurate development of therapeutical strategies. (wur.nl)
Then, we pursued to expand our understanding on the physiological and molecular function of two PPARα target genes, Hilpda and Slc25a47. (wur.nl)
HPS types 7, 8 and 9 are due to mutations in genes encoding subunits of BLOC-1, a complex required for the generation of tubular cargo carriers destined for melanosomes. (chop.edu)
HPS types 3, 5 and 6 are due to mutations in genes encoding subunits of BLOC-2, a complex that directs BLOC-1-dependent cargo carriers with melanosomes. (chop.edu)
Recently, we elucidated the developmental role of tobacco ( Nicotiana tabacum L.) NtTTG2 in association with 12 genes that putatively encode AUXIN RESPONSIVE FACTOR (ARF) proteins, including NtARF8, NtARF17, and NtARF19. (biomedcentral.com)
One of their essential functions is their interaction with specific DNA regions, facilitating the transfer of genetic information encoded in amino acid sequences to regulate particular genes within specific tissues. (peptidesforresearch.com)
Here, the function of regulation is quite clear: expressing energy and carbon, that a number around 0.2% would be the right genes at the right time will enable the cell to make the expected, and that the difference is more or less specific to the lac most of the resources within its reach, by maximizing the uptake operon [7]. (lu.se)

Each of our cells is surrounded by a complex membrane that functions as a biological border, letting ions and nutrients such as salt, potassium and sugar in and out. (phys.org)
Cell recognition proteins allow cells to identify each other and interact. (phys.org)
SARS-CoV-2 B.1.1.7 Spike Protein S1, amino acid Val16-Arg685 (Accession # QHD43416.1), with (HV69-70del, Y144del, N501Y, A570D, P681H) and a C-terminal 8-His tag was expressed in CHO cells. (biolegend.com)
In plant cells, the NtTTG2 protein facilitated the nuclear import of NtARF8 as well as increased its function as a transcription activator. (biomedcentral.com)
LBP polysaccharides showed to have exceptional sources of the necessary cell sugars (glycoconjugates), rhamnose, xylose, sugar, mannose, arabinose and galactose- that are necessary for appropriate immune function and cells to interact. (slideshare.net)
Hemoglobin is present in our red blood cells where it acts as a carrier for oxygen. (mend.me)
2) T cell deficiencies affect the function in killing infected cells or helping other immune cells. (lu.se)
The actin cytoskeleton has several critical functions, including determining cell shape and allowing cells to move. (medlineplus.gov)
In the first part of this thesis, the interaction between the rat CD2 (rCD2) adhesion protein and its ligand rat CD48T92A (rCD48T92A), a high-affinity mutant of the wild type rat CD48, was used to establish a new method of obtaining single-cell binding affinities of T cells interacting with SLBs using imidazole titrations. (lu.se)

Membrane enzymes produce a variety of substances essential for cell function. (phys.org)
S-acylation is reversed by the enzymes acyl protein thioesterases (APTs). (epfl.ch)
Enzymes are the proteins our bodies use to produce chemical reactions. (mend.me)
Iron is required by many of those enzymes in order to function properly. (mend.me)
You will notice that in a large part, these enzymes interact with oxygen, and iron is necessary because of its ability to react with oxygen (which is also why iron rusts). (mend.me)

Functional annotation clustering showed that they belong to cell cycle, organelle or nuclear lumen, protein transport, and DNA binding and repair clusters. (molvis.org)
These findings suggest that TTGs regulate plant development or immunity by either directly or indirectly interacting with their functional partners. (biomedcentral.com)

The site allows the enzyme to be bound by ubiquitin, a protein that the cell uses to mark molecules for breakdown. (epfl.ch)
The two dominating classes of membrane proteins which are in charge of the movement of molecules across the bilayer- a transporter, serves as a vehicle to carry specific molecules crossing the bilayer and channels, which forms narrow pore exists as hydrophilic and favors the passage of water and small inorganic ions. (microbiologynotes.org)
Act as carrier molecules for various solutes is not a function of membrane proteins. (rhumbarlv.com)

The 332 amino acid recombinant protein has a predicted molecular mass of approximately 36.7 kD. (biolegend.com)
6. Chimerical peptides according to the claim 1, characterized by containing a segment inhibitor of the activation of the NS3pro protease which comprise the region Asp50-Glu62 of the NS2B protein from DV2 or the structurally equivalent segment of the protein NS2B from other Flavivirus, or an amino acid sequence showing a sequence similarity higher of equal to the 80% identity. (patentsencyclopedia.com)
8. Chimerical peptides according to the claim 1, characterized by containing a segment inhibitor of the activation of the NS3pro protease which comprise the region Thr20-Leu31 of the NS4A protein from HCV or the structurally equivalent segment of the protein NS4A from other Hepacivirus, or an amino acid sequence showing a sequence similarity higher of equal to the 80% identity. (patentsencyclopedia.com)
PPR proteins have in common a canonical P-type 35 amino acid domain repeated in tandem up to 30 times. (frontiersin.org)
Peptides, comprised of short amino acid chains, are fundamental building blocks of proteins within our bodies. (peptidesforresearch.com)

Finally, transport proteins play an important role in the maintenance of concentrations of ions. (phys.org)

Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. (phys.org)
Like most biochemical processes in the cell, protein S-acylation is reversible to regulate the functions of acylated proteins. (epfl.ch)
In hepatoma cell lines, fatty acids increase Hilpda expression and protein levels. (wur.nl)
The lab is using biochemical and cell biological approaches to dissect the mechanism by which it functions. (chop.edu)
The profound roles of exosomes in homeostasis, stress and several pathological conditions, in conjunction with their selective and cell‑specific composition/function, allude to their use as promising circulating clinical biomarkers of systemic stress and specific pathologic states, and as biocompatible vehicles of therapeutic cargo. (spandidos-publications.com)
Study strongly suggests that goji's distinct polysaccharides work in the body as directors and carriers of cell details and for that reason command and control numerous of the body's biochemical defense systems. (slideshare.net)
Integral membrane proteins are a permanent part of a cell membrane and can either penetrate the membrane (transmembrane) or associate with one or the other side of a membrane (integral monotopic). (rhumbarlv.com)
What are proteins in a cell membrane? (rhumbarlv.com)
Other mutations reduce or eliminate the activity of the enzyme or prevent it from interacting with other proteins within the cell. (medlineplus.gov)

The CusB protein is part of the CusCBA periplasmic Cu(I) efflux system in Gram-negative bacteria, and it was recently reported to play a key role in the functioning of the whole CusCBA system, in which conformational changes as well as the assembly/disassembly process control the opening of the transporter. (biorxiv.org)

Differential expression of GIPs and rapid alterations of GPCR/GIP interaction networks are efficient means to regulate GPCR function in a tissue-specific and spatiotemporal manner to trigger appropriate cellular responses. (nih.gov)
This multifaceted protein serves as an essential carrier of iron and is crucial for cellular growth, immunity, and various physiological processes. (prospecbio.com)

It promotes lipid membrane association of the protein, for instance to the plasma membrane, Golgi apparatus, or inner nuclear membrane. (epfl.ch)
Previous studies have shown that the enzyme is heavily accumulated in the cell's Golgi apparatus, which is the organelle that packages new protein into vesicles before sending them off to the cell's membrane. (epfl.ch)

The lab is using a number of approaches to define the SNAREs involved in fusion of BLOC-1-dependent carriers with maturing melanosomes and to understand how their localization and activity are regulated. (chop.edu)
The data further show that B9d1 is required for normal Hedgehog (Hh) signaling, ciliogenesis, and ciliary protein localization. (medscape.com)

The transport protein pumps certain solutes opposing their electrochemical gradient, it is carried out by process is termed as active transport, and it is usually coupled with metabolic energy like ATP hydrolysis. (microbiologynotes.org)

and lysosomal proteins, such as the transporter MFSD12, that impact melanogenesis indirectly. (chop.edu)

This leads to APT2 being stably bound to the membrane and ready to perform its deacetylating functions. (epfl.ch)
More than 99.9% of the T4 in blood is bound to carrier proteins, specially to thyroxine-binding globulin (TBG), and the free fraction of T4 (free T4, FT4) just accounts for ∼0.03% [ 1 ]. (ijbs.com)
are a household of complicated carbs that are bound to proteins. (slideshare.net)
What does membrane bound protein mean? (rhumbarlv.com)
Platelets play a primary role in this process, interacting with subendothelium-bound von Willebrand factor (vWf) via the membrane glycoprotein (GP) Ib complex. (medscape.com)

B-casein, one of the major calcium carrying proteins in milk, was studied to better understand its function in milk and products made from milk. (usda.gov)
It is among the major cannabis constituents that function throughout the human body, including brain parts. (boutiquetoyou.com)
CRYAA is one of the major lens proteins, accounting for 35% of all crystallins. (molvis.org)
What are the 6 major functions of proteins? (rhumbarlv.com)
The six major functions of membrane proteins are discussed. (rhumbarlv.com)

Research has shown that some of the polyphenols in milk can interact with other constituents of the food, especially proteins. (fcshenxianhu.com)

5. Chimerical peptides according to the claim 1, where the mentioned segment inhibitor of the activation of the NS3pro protease contact at least one residue comprised in the region Glu32-Thr38 of the N-terminal domain of the NS3pro protein from HCV or structurally equivalent residues of the NS3pro protein from other Hepacivirus. (patentsencyclopedia.com)
More knowledge of the underlying mechanism is needed to attain a full understanding of CusB functioning, which is associated with targeting specific and crucial residues in CusB. (biorxiv.org)
We targeted two methionine residues (M227 and M241) that are essential for the proper function of CusB. (biorxiv.org)

Professor Vladimir Khavinson , tasked with addressing this challenge, embarked on his research by delving into previous studies highlighting the role of regulatory peptides in genetic transmission leading to protein production. (peptidesforresearch.com)
Scientific evidence suggests that peptides can specifically interact with DNA, discerning its methylation status. (peptidesforresearch.com)

The S glycoprotein is synthesized as a precursor protein consisting of ~1,300 amino acids that is then cleaved into an amino (N)-terminal S1 subunit (~700 amino acids) and a carboxyl (C)-terminal S2 subunit (~600 amino acids). (biolegend.com)
The highest incidence is reported in the Gujarati Indians, with 1 affected birth per 1,300 (carrier rate, 1 in 18). (medscape.com)

Polysaccharide, Carrier (e.g. (justia.com)
Justia Patents Chemistry: Analytical And Immunological Testing Patents Involving An Insoluble Carrier For Immobilizing Immunochemicals Patents Carrier Is Organic Patents Polysaccharide, Carrier (e.g. (justia.com)
Conjugation with a protein carrier improves the effectiveness of polysaccharide vaccines by inducing T-lymphocyte-dependent immunologic function ( 2 ). (cdc.gov)

Such proteins are involved in immune response, for example. (phys.org)
Understanding how proteins interact entails studying the binding affinity (strength) and the lifetime (duration) of the protein-protein interaction to better decompose how an immune response is initiated and how we can explore this knowledge to treat diseases. (lu.se)

He also showed that double-stranded (ds)RNA- and ZDNA binding proteins had a role in poxvirus pathogenesis. (cdc.gov)
In this study, we tested the role of an uncharacterized ER protein, PfGRP170, in regulating these key functions by generating conditional mutants. (cdc.gov)

1. Dilute the recombinant mouse Cathepsin B to 10 μg/ml in activation buffer (25 mM MES, 1 mM DTT, pH 5.0) and incubate the protein at 25°C for 3 min. (biolegend.com)
By delving into the diverse functions of human recombinant transferrin, this research aims to expand our understanding of its physiological roles and clinical applications. (prospecbio.com)
The HuProt microarray results showed that the signals of 343 proteins were higher in the recombinant CRYAA group than in the control group. (molvis.org)
When recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 is immobilized at 2 μg/mL, recombinant human ACE2-Fc Chimera (Cat. (biolegend.com)
Recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 was aliquoted in PBS at 0.2 mg/mL. (biolegend.com)

HspA9 suppresses nuclear translocation, transcriptional activation, and control centrosome-duplication functions of p53. (qedbio.com)

The LDL receptor is a transmembrane protein of the plasma membrane. (rhumbarlv.com)

Intrinsic fluorescence of single Trp (position 143) was monitored as a function of temperature and denaturant concentration to gain better insight on the molecular response on a tertiary level. (usda.gov)
The advent of microarray analysis enables a better understanding of the functions of CRYAA as a molecular chaperone. (molvis.org)
In the second part of this thesis, we characterized the physiological and molecular function of HILDPA in ATM in the context of obesity-induced inflammation and in hepatocytes during NASH. (wur.nl)

In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers. (phys.org)
S.A.D., the researchers pointed out, can also strike in summer and interact with substance use disorders, but fortunately there are a number of promising therapies for the condition. (inverse.com)

Intrinsic membrane proteins are tightly embedded in the hydrophobic core, whereas extrinsic membrane proteins associate with their required leaflet. (rhumbarlv.com)

Within this cohort we compared the number of mutation carriers fulfilling clinical selection criteria with the total number of carriers identified. (biomedcentral.com)
Remarkably, neither of the ATM , RAD51D , CHEK2 and PALB2 mutation carriers had a family history. (biomedcentral.com)
Most importantly, among the 57 mutation carriers, ten (17.5%) would be missed using current clinical testing criteria including five (8%) with BRCA1/2 mutations. (biomedcentral.com)
the p.Ser101Arg mutation abrogates the ability of B9d2 to interact with Mks1, which suggests that this mutation compromised B9d2 function. (medscape.com)

For digital modulation systems, for example binary frequency shift keying BFSK, where a binary signal modulates the carrier, the modulation index is given by. (tradegenix.net)

Anatomy13

Organisms14

Chemicals and Drugs111

Analytical, Diagnostic and Therapeutic Techniques and Equipment39

Phenomena and Processes74

Disciplines and Occupations2

Technology, Industry, Agriculture2

Information Science9

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Receptors12

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Membrane protein6

Membranes9

Mitochondrial7

Biomolecules2

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Regulates2

Molecule4

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Hsp701

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Extracellular2

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Pathways4

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Concentrations1

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Metabolic1

Indirectly1

Bound5

Major5

Constituents1

Residues3

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1,3002

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Role2

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Molecular3

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Associate1

Mutation4

Modulates1