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  • Gene
  • GO annotations related to this gene include integrin binding . (genecards.org)
  • Integrins deliver signals through multiprotein complexes at the cell surface, which interact with cytoskeletal and signaling proteins to influence gene expression, cell proliferation, morphology, and migration ( Siegers 2018 ). (tcdb.org)
  • mice
  • 1. Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. (herokuapp.com)
  • HUMAN
  • Isolated cells were immunoreactive for cytokeratin-7 (CK-7), placental growth factor, placental alkaline phosphatase, human leukocyte antigen G1 (HLA-G1), and α1 and α5 integrins, similarly to the EVT markers from first trimester placental villi. (biomedcentral.com)
  • alterations
  • Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology. (genecards.org)
  • 2017). Inside the Cell: Integrins as New Governors of Nuclear Alterations? (tcdb.org)
  • beta
  • The alpha IIb beta 3 integrin on platelets, for example, is only able to bind fibrinogen, Von Willebrand factor and other blood components when the platelet itself is activated. (anaesthetist.com)
  • levels
  • It was found that the levels of integrin alpha1 and VE-cadherin mRNA increased during co-culturing of activated endothelium cells with mesenchymal stromal cells. (nih.gov)