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  • somatostatin
  • The Endocrine Society suggests use of a somatostatin analog in select patients preoperatively to reduce surgical risk from severe comorbidities and as initial adjuvant therapy in patients with persistent, significant disease (ie, moderate to severe signs/symptoms of growth hormone excess and without local mass effects) postoperatively. (drugs.com)
  • Glycemia
  • Reasons for the discrepancy between human and animal studies are unknown, but a major contributing factor may be the extent of glycemia control (including recurrent hypoglycemia) prior to the episode of severe hypoglycemia. (diabetesjournals.org)
  • Pancreas transplantation should be considered an acceptable therapeutic alternative to continued insulin therapy in diabetic patients with imminent or established end-stage renal disease who have had or plan to have a kidney transplant, because the successful addition of a pancreas does not jeopardize patient survival, may improve kidney survival, and will restore normal glycemia. (diabetesjournals.org)
  • hyperinsulinemia
  • Type A, which affects young women, is characterized by severe hyperinsulinemia, usually present with obesity and features of hyperandrogenism. (medscape.com)
  • prandial
  • ORLANDO - New research suggests it's feasible for hospitals to use an automated closed-loop insulin delivery system - free of prandial boluses and carbohydrate counts - to improve glucose control in noncritical patients with type 2 diabetes mellitus (T2DM). (the-hospitalist.org)
  • This was not a hybrid system, and it did not include prandial insulin boluses or input of the timing and carbohydrate content of meals. (the-hospitalist.org)
  • Neutral
  • Neutral insulin in a dosage of 2-4 units per hour is infused via a paediatric giving set to achieve a sustained physiological elevation of insulin levels. (garvan.org.au)
  • Study selection Randomized controlled trials or non-randomized studies of long acting (glargine, detemir) and intermediate acting (neutral protamine Hagedorn (NPH), lente) insulin for adults with type 1 diabetes were included. (bmj.com)
  • isophane insulin (neutral protamine Hagedorn (NPH)) and zinc insulin (lente) have been used commonly since the 1950s. (bmj.com)
  • adults
  • We previously reported that transgenic mice expressing a dominant-negative form (Kir6.2G132S) of Kir6.2, a subunit of the K ATP channel, specifically in β-cells develop severe hyperglycemia in adults (8 weeks of age). (diabetesjournals.org)
  • Although neonatal rats injected with streptozotocin later show an improvement of hyperglycemia ( 21 - 23 ), no good animal models have been reported showing spontaneous recovery from the diabetic state in adults. (diabetesjournals.org)
  • abnormalities
  • Originating from an absolute or relative lack of insulin, it gives way to abnormalities in the metabolism of carbohydrates, proteins and fat in the body. (allayurveda.com)
  • treatment
  • LAR depot suspension: Long-term treatment of severe diarrhea and flushing episodes associated with metastatic carcinoid tumors. (drugs.com)
  • At my center, Cedars-Sinai in Los Angeles, we have recently used an approach that blended standard insulin treatment with more aggressive treatment. (the-hospitalist.org)
  • Counsel patients on the proper prevention and treatment of hypoglycemia. (ihs.gov)
  • The treatment options are limited for this condition and controlling the hyperglycemia is a daunting task, hence multi-disciplinary approach is important when managing this challenging clinical condition. (springer.com)