Insulin ResistanceInsulinDiabetes Mellitus, Type 1Protein KinasesProtein Kinase CReceptor, InsulinPhosphorylationCyclic AMP-Dependent Protein KinasesSignal TransductionCalcium-Calmodulin-Dependent Protein KinasesPhosphatidylinositol 3-KinasesEnzyme ActivationProtein-Serine-Threonine KinasesProtein Kinase InhibitorsBlood GlucoseCalciumGlucoseCalcium-Calmodulin-Dependent Protein Kinase Type 2Insulin AntibodiesMolecular Sequence DataDiabetes Mellitus, Type 2Calcium-Calmodulin-Dependent Protein Kinase Type 1Insulin Receptor Substrate ProteinsCyclic AMPCyclic GMP-Dependent Protein KinasesCells, CulturedKineticsCell LineAmino Acid SequenceAlbuminuriaEnzyme InhibitorsMitogen-Activated Protein KinasesIsoenzymesGlucose Tolerance TestPhosphatidylinositolsObesityIslets of LangerhansMAP Kinase Signaling SystemTime FactorsProto-Oncogene Proteins c-aktCalmodulinGlucose Clamp TechniqueHypoglycemic AgentsDiabetic KetoacidosisMutationPhosphoproteinsp38 Mitogen-Activated Protein KinasesProtein BindingHemoglobin A, GlycosylatedAdipose TissueHyperinsulinismParamecium tetraureliaDiseases in TwinsTwins, MonozygoticBlotting, WesternMuscle, SkeletalTetradecanoylphorbol AcetateMitogen-Activated Protein Kinase 1C-PeptideeIF-2 KinaseLiverRNA, MessengerBase SequenceDiabetes MellitusHypoglycemiaProtein Kinase C-alphaSubstrate SpecificityRats, Sprague-DawleyTransfectionDose-Response Relationship, DrugInsulin Infusion SystemsModels, BiologicalMitogen-Activated Protein Kinase 3Drug ResistanceDiabetic NephropathiesGene Expression RegulationMitogen-Activated Protein Kinase KinasesMice, Inbred C57BLInsulin, Long-ActingJNK Mitogen-Activated Protein KinasesCyclic AMP-Dependent Protein Kinase Catalytic SubunitsBinding SitesAMP-Activated Protein KinasesCyclic GMPInsulin AntagonistsSerineComplement C4Adenosine TriphosphateCell MembraneCattleAdipocytesProtein Kinase C-deltaProtein-Tyrosine KinasesCarrier ProteinsRecombinant ProteinsAndrostadienesPregnancy in DiabeticsPhosphoprotein PhosphatasesCalcium-Binding ProteinsRats, Wistar