Receptor, InsulinInsulin ResistanceInsulinInsulin Receptor Substrate ProteinsGlucoseGlucose Tolerance TestBlood GlucoseDiabetes Mellitus, Type 2ObesityAdipose TissueGlucose Clamp TechniqueHypoglycemic AgentsHyperinsulinismPhosphorylationPhosphoproteinsSignal TransductionMuscle, SkeletalLiverAdipocytesInsulin AntagonistsInsulin AntibodiesGlucose Transporter Type 4Insulin, Long-ActingIslets of LangerhansDrug ResistanceFastingPhosphatidylinositol 3-KinasesHyperglycemiaFatty Acids, NonesterifiedInsulin-Secreting CellsGlucose IntoleranceDeoxyglucoseAdiponectinDrug Resistance, MicrobialReceptor, IGF Type 1Drug Resistance, BacterialProto-Oncogene Proteins c-aktMetabolic Syndrome XTriglyceridesLeptinTyrosineInsulin-Like Growth Factor IHomeostasisInsulin LisproC-PeptideDietary FatsBody WeightFatty LiverMonosaccharide Transport ProteinsMice, ObeseKineticsProinsulinDiabetes MellitusDiet, High-FatBody Mass IndexCell LineProtein-Tyrosine KinasesInsulin Infusion SystemsLipidsGlucagonGlycogenLipid MetabolismCells, CulturedDrug Resistance, NeoplasmMice, Inbred C57BLMolecular Sequence Data3T3-L1 CellsThiazolidinedionesDiabetes Mellitus, ExperimentalRats, ZuckerInsulin, Regular, PorkInsulin AspartMice, KnockoutInsulin, IsophaneAdiposityTime FactorsRNA, MessengerPolycystic Ovary SyndromeRats, WistarPhosphotyrosineCricetinaeResistin3T3 CellsCHO CellsEnzyme ActivationInsulinsInsulin, Regular, HumanMutationBody CompositionDiabetes Mellitus, Type 1Drug Resistance, MultipleIntra-Abdominal FatMetforminMuscle ProteinsVascular ResistanceProtein Tyrosine Phosphatase, Non-Receptor Type 1Dose-Response Relationship, DrugIntracellular Signaling Peptides and ProteinsBiological TransportDisease Resistance