Cytoplasmic GranulesSecretory VesiclesInsulinExocytosisInsulin-Secreting CellsIslets of LangerhansInsulinomaReceptor, InsulinMicroscopy, ElectronGlucoseChromograninsProinsulinChromaffin GranulesChromogranin BSecretory Pathwayrab3A GTP-Binding ProteinReceptor-Like Protein Tyrosine Phosphatases, Class 8Microscopy, FluorescenceAdenoma, Islet CellChromogranin AMicroscopy, ImmunoelectronCell MembraneVesicular Transport ProteinsHistocytochemistrySyntaxin 1Golgi ApparatusInsulin ResistanceCell LineMembrane Fusionrab GTP-Binding ProteinsCells, CulturedGreen Fluorescent ProteinsCalciumQa-SNARE ProteinsHydroxybutyratesPancreasMunc18 ProteinsVesicle-Associated Membrane Protein 2Synaptosomal-Associated Protein 25Rats, Mutant StrainsMicroscopy, ConfocalAcid PhosphataseMast CellsLysosomesSecretogranin IIInsulin Receptor Substrate ProteinsNerve Tissue ProteinsOrganellesParotid GlandProtein TransportMice, KnockoutGerm CellsMicroscopy, Electron, TransmissionInsulin, Long-ActingRats, WistarCerebellumPC12 CellsPolyestersPituitary Gland, AnteriorLuminescent ProteinsCytoplasmStarchInclusion BodiesMolecular Sequence DataInsulin AntibodiesHypoglycemic AgentsThiamine PyrophosphatasePancreatic NeoplasmsBiological TransportRNA, MessengerExocrine GlandsGlyburidePigments, BiologicalChromaffin SystemInsulin AntagonistsFluorescent Antibody TechniqueCaenorhabditis elegansCarboxypeptidase HRecombinant Fusion ProteinsMice, Inbred C57BLCell DegranulationCell FractionationAdrenal MedullaNeurosecretory SystemsPituitary GlandChromaffin CellsCarrier ProteinsInsulin LisproChymasesrab3 GTP-Binding ProteinsCaenorhabditis elegans ProteinsRibonucleoproteinsGlucagonDentate GyrusGlucose Tolerance TestKineticsSubcellular FractionsImmunohistochemistryMicroscopy, Electron, ScanningProprotein Convertase 2