Insulin, Long-ActingInsulinsInsulin AspartInsulinHypoglycemic AgentsReceptor, InsulinClinical Trials, Phase III as TopicHemoglobin A, GlycosylatedDrug Administration ScheduleDiabetes Mellitus, Type 2Insulin ResistanceInsulin Receptor Substrate ProteinsGlucoseTreatment OutcomeInsulin AntibodiesDiabetes Mellitus, Type 1Blood GlucoseInsulin AntagonistsIslets of LangerhansInsulin LisproGlucose Tolerance TestInsulin Infusion SystemsGlucose Clamp TechniqueInsulin, IsophaneInsulin, Regular, PorkHyperinsulinismAdipose TissueInsulin-Secreting CellsGlucagonObesityInsulin, Regular, HumanC-PeptideProinsulinFastingHyperglycemiaLiverMuscle, SkeletalSignal TransductionFatty Acids, NonesterifiedGlucose Transporter Type 4AdipocytesInsulin, Short-ActingHypoglycemiaPhosphorylationDiabetes Mellitus, ExperimentalDiabetes MellitusGlucose IntoleranceInsulin-Like Growth Factor ILeptinDeoxyglucoseBody WeightTriglyceridesPhosphoproteinsMonosaccharide Transport ProteinsPhosphatidylinositol 3-KinasesInsulinomaCells, CulturedBiphasic InsulinsKineticsProto-Oncogene Proteins c-aktGlycogenHomeostasisAdiponectinPostprandial PeriodRats, WistarLipidsTime FactorsPancreasGlucagon-Like Peptide 1Cell LineBody Mass IndexMetforminDietary FatsDose-Response Relationship, DrugMice, ObeseLipid MetabolismRNA, MessengerRats, Inbred StrainsThiazolidinediones3T3-L1 CellsLipolysisMuscle ProteinsRats, Sprague-DawleyReceptor, IGF Type 1Rats, ZuckerMice, Inbred C57BLMetabolic Syndrome XTolbutamideInfusions, SubcutaneousEatingDietary CarbohydratesGene Expression RegulationBody CompositionBiological TransportDiet, High-FatReference ValuesStreptozocinMice, KnockoutEnergy MetabolismGlycogen Synthase