Cyclic Nucleotide Phosphodiesterases, Type 13',5'-Cyclic-AMP PhosphodiesterasesCyclic Nucleotide Phosphodiesterases, Type 4Cyclic Nucleotide Phosphodiesterases, Type 3Cyclic Nucleotide Phosphodiesterases, Type 2Phosphoric Diester Hydrolases2',3'-Cyclic-Nucleotide PhosphodiesterasesNucleotides, CyclicPhosphodiesterase Inhibitors3',5'-Cyclic-GMP PhosphodiesterasesCyclic Nucleotide Phosphodiesterases, Type 5Cyclic GMPCyclic Nucleotide Phosphodiesterases, Type 7Cyclic AMPRolipram1-Methyl-3-isobutylxanthinePurinonesIsoenzymesMolecular Sequence DataInsulinCalmodulinAmino Acid SequenceKineticsCyclic Nucleotide Phosphodiesterases, Type 6Receptor, InsulinNucleotidesPhosphodiesterase 3 InhibitorsPhosphodiesterase 4 Inhibitors4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinoneInsulin ResistanceDibutyryl Cyclic GMPTheophyllinePhosphodiesterase IBucladesineCyclic Nucleotide-Gated Cation ChannelsPhosphorus-Oxygen LyasesMilrinonePyrrolidinonesAdenine NucleotidesCyclic AMP-Dependent Protein KinasesAdenylate CyclaseSecond Messenger SystemsCyclic GMP-Dependent Protein KinasesSignal TransductionGlucoseBase SequenceInsulin Receptor Substrate ProteinsColforsinPapaverineCyclic IMPCalciumGuanylate CyclaseInsulin, Long-ActingCloning, MolecularPolymorphism, Single NucleotideCattleEnzyme ActivationCells, Cultured8-Bromo Cyclic Adenosine MonophosphatePhosphodiesterase 5 InhibitorsInsulin AntibodiesBinding SitesHypoglycemic AgentsIsoproterenolGuanine NucleotidesRNA, MessengerHydrolysisXanthinesLiverPhosphorylationSubstrate SpecificityDose-Response Relationship, DrugCatalytic DomainInsulin AntagonistsCell LineVinca AlkaloidsCyclic P-OxidesIslets of LangerhansSequence Homology, Amino AcidMutationInsulin LisproPyrophosphatasesProtein Structure, TertiaryDNAGlucose Tolerance TestGene Expression Regulation, EnzymologicModels, MolecularSequence Alignment