Islets of LangerhansInsulinCell LineReceptor, InsulinCell Line, TumorCell Line, TransformedInsulin ResistanceTumor Cells, CulturedInsulin Receptor Substrate ProteinsGlucoseInsulin, Long-ActingInsulin AntibodiesHypoglycemic AgentsRNA, MessengerInsulin AntagonistsSignal TransductionTransfectionInsulin LisproMolecular Sequence DataGlucose Tolerance TestBase SequenceDiabetes Mellitus, Type 2Insulin Infusion SystemsPhosphorylationGlucose Clamp TechniqueApoptosisCells, CulturedBlotting, WesternInsulin AspartInsulin, IsophaneAdipose TissueInsulin-Secreting CellsHyperinsulinismInsulin, Regular, PorkGene Expression Regulation, NeoplasticGene ExpressionReverse Transcriptase Polymerase Chain ReactionDose-Response Relationship, DrugCell SurvivalCell ProliferationGene Expression RegulationKineticsLiverGlucagonCell DivisionInsulinsObesityTime FactorsProinsulinAntineoplastic AgentsCricetinaeInsulin, Regular, HumanC-PeptidePromoter Regions, GeneticTranscription, GeneticFastingMice, NudeAmino Acid SequenceCell DifferentiationMuscle, SkeletalMutationBlood GlucoseHyperglycemiaPhosphoproteinsDrug Screening Assays, AntitumorProto-Oncogene Proteins c-aktAdipocytesDiabetes Mellitus, Type 1Phosphatidylinositol 3-KinasesNeoplasm ProteinsTranscription FactorsEnzyme ActivationFatty Acids, NonesterifiedGlucose Transporter Type 4Down-RegulationFlow CytometryRecombinant ProteinsPhenotypeProto-Oncogene ProteinsHypoglycemiaInsulin, Short-ActingDNA-Binding ProteinsDNADrug Resistance, NeoplasmInsulin-Like Growth Factor IEnzyme InhibitorsNeoplasm TransplantationMice, Inbred C57BLDrug ResistanceDiabetes Mellitus, ExperimentalRNA, Small InterferingBreast NeoplasmsL Cells (Cell Line)Clone CellsDNA PrimersBlotting, NorthernCell MembraneBiological TransportCHO CellsPolymerase Chain Reaction