InsulinReceptor, InsulinInsulin ResistanceInsulin Receptor Substrate ProteinsGlucoseInsulin, Long-ActingInsulin AntibodiesHypoglycemic AgentsInsulin AntagonistsIslets of LangerhansInsulin LisproGlucose Tolerance TestDiabetes Mellitus, Type 2Insulin Infusion SystemsGlucose Clamp TechniqueInsulin AspartInsulin, IsophaneInsulin, Regular, PorkHyperinsulinismAdipose TissueInsulin-Secreting CellsInsulinsGlucagonObesityInsulin, Regular, HumanC-PeptideProinsulinFastingBlood GlucoseHyperglycemiaLiverMuscle, SkeletalDiabetes Mellitus, Type 1Signal TransductionFatty Acids, NonesterifiedGlucose Transporter Type 4AdipocytesInsulin, Short-ActingHypoglycemiaPhosphorylationDiabetes Mellitus, ExperimentalDiabetes MellitusGlucose IntoleranceInsulin-Like Growth Factor ILeptinDeoxyglucoseBody WeightTriglyceridesPhosphoproteinsMonosaccharide Transport ProteinsPhosphatidylinositol 3-KinasesInsulinomaCells, CulturedBiphasic InsulinsKineticsProto-Oncogene Proteins c-aktHemoglobin A, GlycosylatedGlycogenHomeostasisAdiponectinPostprandial PeriodRats, WistarLipidsTime FactorsPancreasGlucagon-Like Peptide 1Cell LineBody Mass IndexMetforminDietary FatsDose-Response Relationship, DrugMice, ObeseLipid MetabolismRNA, MessengerRats, Inbred StrainsThiazolidinediones3T3-L1 CellsLipolysisMuscle ProteinsRats, Sprague-DawleyReceptor, IGF Type 1Rats, ZuckerMice, Inbred C57BLMetabolic Syndrome XTolbutamideInfusions, SubcutaneousEatingDietary CarbohydratesGene Expression RegulationBody CompositionBiological TransportDiet, High-FatReference ValuesStreptozocinMice, KnockoutEnergy MetabolismGlycogen SynthaseSomatostatinAdiposityGluconeogenesis