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  • Immunohistochemistry
  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. (lsbio.com)
  • peptide
  • Synthetic peptide (KLH-coupled) derived from the sequence of human insulin. (novusbio.com)
  • Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. (genetex.com)
  • After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. (genetex.com)
  • Her plasma glucose was 40 mg/dl, insulin 103.7 μU/ml, and C-peptide 4.1 ng/ml. (diabetesjournals.org)
  • The authors state, "Patients with this condition have low circulation insulin, C-peptide levels, and refractory hypoglycemia. (diabetesjournals.org)
  • Free insulin levels may be normal or high, and C-peptide levels are not suppressed ( 3 ). (diabetesjournals.org)
  • Detects a band of approximately 165 kDa (predicted molecular weight: 156 kDa).Can be blocked with Human Insulin Receptor peptide (ab197200) . (abcam.com)
  • A synthetic peptide corresponding to a sequence at the N-terminal of human Insulin Ra, identical to the related rat and mouse sequence. (novusbio.com)
  • A synthetic peptide corresponding to a sequence at the C-terminus of human Insulin Receptor(1353-1372aa RSYEEHIPYTHMNGGKKNGR), different from the related rat and mouse sequences by two amino acids. (bosterbio.com)
  • Localization
  • Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies. (lsbio.com)
  • diabetes
  • Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. (novusbio.com)
  • Deficiency of insulin results in diabetes mellitus. (genetex.com)
  • The factors leading to low secretion or absence of insulin cause the condition known as Diabetes. (lybrate.com)
  • This test is suggested to a person who is in the high risk zone for diabetes type 1 or is showing allergic reaction to insulin or if insulin therapy is proving ineffective to control blood sugar levels. (lybrate.com)
  • This test does not react, for instance, with several of the insulin analogs used to treat diabetes as indicated in Table 1 below. (lybrate.com)
  • In 1970 we reported the spontaneous remission of severe insulin-resistant diabetes mellitus in a patient with features of scleroderma (1). (annals.org)
  • BLACKARD WG, ANDERSON JH, MULLINAX F. Anti-Insulin Receptor Antibodies and Diabetes. (annals.org)