• We extracted their altitude information from their residential addresses and determined if they had metabolic syndrome by the presence of three or more of the following components: abdominal obesity, reduced high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, elevated glucose, and high blood pressure at recruitment. (bvsalud.org)
  • According to the 2005 IDF criteria, subsequently revised in 2009, abdominal obesity is identified as the waist circumference of ≥80 cm in women and ≥94 cm in men. (hindawi.com)
  • Abdominal obesity is the major disorder constituting a base for the development of metabolic syndrome. (hindawi.com)
  • Evidence from the conducted studies has revealed that abdominal obesity (assessed based on the waist circumference) plays a very important role in the development of metabolic disorders and in the assessment of cardiovascular risk. (hindawi.com)
  • Due to the limitations of BMI methodology, current reports by the World Health Organization and other organizations suggest combining the measurements of BMI and abdominal obesity [ 11 ]. (hindawi.com)
  • This has led to an increasing evidence for abdominal obesity indices such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) as predictors of CVD [ 16 , 17 ]. (hindawi.com)
  • However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
  • This agglomeration of abnormalities has been referred to as the metabolic syndrome which can be identified by the presence of three of the five following variables: abdominal obesity, elevated triglyceride concentrations, low HDL-cholesterol levels, increased blood pressure and elevated fasting glucose. (researchgate.net)
  • Metabolic syndrome linked to abdominal obesity is also predictive of recurrent coronary events both in post-myocardial infarction patients and among coronary artery disease men who underwent a revascularization procedures. (researchgate.net)
  • The severity of the metabolic syndrome (MetS) is significantly associated with future coronary heart disease (CHD) among individuals without baseline Type 2 diabetes. (biomedcentral.com)
  • However, the validity of assessing MetS severity among individuals with diabetes is unknown. (biomedcentral.com)
  • To assess for differences in MetS severity by timing of Type 2 diabetes diagnosis and to assess for associations between MetS severity and future CHD among individuals with diabetes. (biomedcentral.com)
  • We used Cox-regression techniques to assess hazard ratios (HR) of CHD based on a sex- and race/ethnicity-specific MetS-severity Z-score (standard MetS score) and a similar MetS-severity score formulated without incorporating glucose as a component of MetS (no-glucose MetS score). (biomedcentral.com)
  • For both the standard- and no-glucose MetS-severity scores, scores were highest in the baseline-diabetes group, lowest in the never-diabetes group and intermediate in the incident-diabetes groups. (biomedcentral.com)
  • MetS severity appears to provide an estimate of metabolic disarray in the setting of diabetes and is predictive of future CHD events beyond HbA1c. (biomedcentral.com)
  • Identifying MetS severity among individuals with diabetes may help in identifying those at higher risk, who could then receive further preventative treatment. (biomedcentral.com)
  • These MetS-severity scores were derived and have been assessed only in populations without baseline diabetes. (biomedcentral.com)
  • As such, it is unclear among individuals with diabetes whether assessing MetS severity would be an accurate means of tracking metabolic abnormalities over time and predicting future CHD. (biomedcentral.com)
  • For the standard five-component MetS-severity score, it is possible that extreme fluctuations in fasting glucose may unduly influence the overall calculated score, lowering its predictive power. (biomedcentral.com)
  • For the no-glucose score, it is possible that any CHD risk related to abnormalities in the other four MetS components would be inconsequential relative to the risk conferred by the degree of diabetes control. (biomedcentral.com)
  • In this study, we investigated the additional effect of impaired glucose tolerance (IGT), an essential component of MetS, on retinal degeneration using the WNIN/GR-Ob rat model. (molvis.org)
  • The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
  • The aim of this study was to evaluate acylated ghrelin and obestatin levels and their ratio in obese and normal-weight children and adolescents, and their association with metabolic syndrome (MetS) parameters. (mdpi.com)
  • Each component of the MetS is an independent risk factor for cardiovascular disease and together enhances and compounds the atherosclerotic risk in the individual. (kauveryhospital.com)
  • It is the pathophysiologic aspects of obesity coupled with MetS that leads to changes in hemodynamics, atherosclerosis and calcification, myocardial metabolism, microvascular dysfunction that culminates in myocardial infarction and heart failure. (kauveryhospital.com)
  • To determine the prevalence of the metabolic syndrome (MetS) and its related risk factors in a group of healthy subjects. (org.sa)
  • M etabolic syndrome (MetS) prevalence has been rising steadily over the past few decades all over the world. (org.sa)
  • While in 2005 the International Diabetes Federation (IDF) added central obesity as a requirement for MetS diagnosis, focusing on waist circumference as a simple screening tool. (org.sa)
  • Metabolic syndrome (MetS) is a cluster of interrelated metabolic conditions which increase the risk of developing cardiovascular disease (Kaur, 2014). (ugr.es)
  • In addition, some research has supported the association of very low-, low- and high-density lipoprotein (VLDL HDL) particle diameters with components of the metabolic syndrome (MetS), although this has been the focus of less research. (biomedcentral.com)
  • While small LDL diameters remain associated with IR and the MetS, the occurrence of these in conjunction with a shift to overall larger VLDL diameter may identify those with the highest fasting glucose, TG and WC within the MetS. (biomedcentral.com)
  • RÉSUMÉ Dans une enquête transversale réalisée en 2005, nous avons déterminé la prévalence du syndrome métabolique (MetS) et d'autres facteurs de risque de maladie cardiovasculaire athérosclérotique dans un échantillon de 342 Palestiniens de Jérusalem-Est âgés de 20 ans ou plus et sélectionnés parmi les affiliés au système national d'assurance maladie. (who.int)
  • The metabolic syndrome (MetS) refers to up to 6 months post-delivery. (who.int)
  • The presence of MetS is associated with Palestinians in East Jerusalem are included increased risk for developing atherosclerotic in the national health insurance scheme, a cardiovascular disease (ASCVD) and type 2 target sample of 400 subjects was selected diabetes [ 2 ]. (who.int)
  • Metabolic syndrome (MetS) is a cluster of metabolic risk factors for cardiovascular disease and type 2 diabetes. (bvsalud.org)
  • According to the International Diabetes Federation, a quarter of the world's adult population has MetS, and more cases are diagnosed in males over 40 years of age 1 . (bvsalud.org)
  • We analyzed data from participants of the Atherosclerosis Risk in Communities study, including 1419 with- and 7241 without diabetes, followed during 4 visits and adjudicated CHD diagnoses over a 20-year period. (biomedcentral.com)
  • These health conditions are well known to develop along with, or be precursors to atherosclerosis, cardiovascular disease, and diabetes. (nih.gov)
  • All of the individual components of metabolic syndrome are risk factors for atherosclerosis (hardening and narrowing of the arteries). (mydr.com.au)
  • Post-mortem analyses of coronary arteries have indicated that obesity (associated with a high accumulation of abdominal fat measured at autopsy) was predictive of earlier and greater extent of large vessels atherosclerosis as well as increase of coronary fatty streaks. (researchgate.net)
  • GW-501516 SARM studies were famously pioneered by world-class biologist Ronald Evans at the Salk Institute in La Jolla, CA. He regarded GW-501516 as the long sought-after molecule to confer metabolic protection, calling it "a multifaceted therapeutic for metabolic syndrome with the potential to control weight gain, enhance physical endurance, improve insulin sensitivity, and ameliorate atherosclerosis" [1]. (umbrellalabs.is)
  • There are increased risk for: Atherosclerosis, Peripheral vascular disease, Coronary heart disease, Heart attack, Stroke and Type 2 diabetes. (bvsalud.org)
  • PURPOSE OF REVIEW: Polycystic ovarian syndrome (PCOS) is a common endocrine disease characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology and causing various reproductive, metabolic, cardiovascular, oncological, and psychological complications. (bvsalud.org)
  • Having three or more of these factors will result in a diagnosis of metabolic syndrome and will increase your risk of health complications including type 2 diabetes. (healthline.com)
  • What are the complications of metabolic syndrome? (healthline.com)
  • The complications that may result from metabolic syndrome are frequently serious and long-term (chronic). (healthline.com)
  • If you are diagnosed with metabolic syndrome, the goal of treatment will be to reduce your risk of developing further health complications. (healthline.com)
  • By changing your lifestyle, you can help delay or even prevent the complications of metabolic syndrome (heart disease, stroke and diabetes) from developing. (mydr.com.au)
  • In the United States, obesity and its complications cause as many as 300,000 premature deaths each year, making it second only to cigarette smoking as a preventable cause of death. (msdmanuals.com)
  • It is also one of the most significant long-term complications in terms of morbidity and mortality for individual patients with diabetes. (medscape.com)
  • screening for comorbidities of obesity should be applied in a hierarchal, logical manner for early identification before more serious complications result. (medscape.com)
  • Introduction-Le diabète est un véritable problème de santé publique du fait de ses nombreuses complications potentielles, notamment cardiovasculaires. (bvsalud.org)
  • However, ART is restricted by adverse drug reactions, resulting in medication non-ad- treatment barriers such as complex dosing, drug-drug in- herence, treatment failure and poor response rate of pa- teractions, toxicities and metabolic complications. (bvsalud.org)
  • Metabolic syndrome can significantly increase your risk for developing cardiovascular disease, stroke, or type 2 diabetes. (integrative-medicine-clinics.com)
  • however, this may vary significantly by age, dietary habits, gender, and even among participants with morbid obesity [ 9 ]. (hindawi.com)
  • Also, the microvascular tone and microvascular density are significantly impacted by obesity. (kauveryhospital.com)
  • Short-term calorie restriction ( for about six months) has significantly improved multiple cardiovascular health, insulin sensitivity, and mitochondrial function. (healthifyme.com)
  • Metabolic syndrome prevalence and defining criteria are significantly high among Iraqi university students. (org.sa)
  • Nearly 35 percent of U.S. adults are estimated to have metabolic syndrome, which significantly increases the risk of cardiovascular disease and type 2 diabetes. (medindia.net)
  • The U.K. researchers found Montmorency tart cherry juice led to a significant, clinically-relevant reduction in systolic blood pressure when compared to the placebo 2 hours after consumption, and Montmorency tart cherry juice and Montmorency tart cherry capsules both lowered insulin levels significantly more than the placebo at 1 hour and 3 hours, respectively. (medindia.net)
  • The prevalence of metabolic syndrome was significantly lower in HAART and non-HAART users compared with NHANES participants unadjusted for body mass index (BMI). (natap.org)
  • HRV can be used to estimate autonomic nervous control of the cardiovascular system and reduced HRV significantly increases cardiovascular mortality 9 . (bvsalud.org)
  • We used stepwise regression analysis to determine whether anthropometric measurements significantly predicted metabolic syndrome. (cdc.gov)
  • Stepwise regression showed that only waist circumference significantly predicted metabolic syndrome. (cdc.gov)
  • ing of metabolic abnormalities which hospital in the capital city of Jordan, Am- Data collection includes hyperlipidaemia [elevated tri- man), and is the primary teaching clinic glycerides (TG), low serum high-den- for the family medicine programme. (who.int)
  • Abnormalities in myocardial fuel substrate selection in obesity have been noted. (kauveryhospital.com)
  • Good Metabolic Health is the absence of abnormalities in blood sugar levels, triglycerides, blood pressure levels and central obesity. (healthifyme.com)
  • Any abnormalities in metabolism can lead to metabolic syndrome. (healthifyme.com)
  • Most of the metabolic abnormalities defining metabolic syndrome are observed in HIV. (natap.org)
  • Studies showed that 65% of the world's population live in countries where overweight and obesity kills more people than underweight (World Health Organization, 2012). (directcurrentmusic.com)
  • Acai-rich smoothies may reduce cholesterol levels and improve metabolic syndrome risk factors in overweight subjects, suggest preliminary findings from a pilot study. (tamarindfruit.com)
  • 'In this uncontrolled pilot study, consumption of acai fruit pulp reduced levels of selected markers of metabolic disease risk in overweight adults, indicating that further studies are warranted,' concluded the researchers. (tamarindfruit.com)
  • If you suffer from metabolic syndrome, it could be due to the genetic makeup you inherited from your parents, problems associated with being overweight, or the result of leading an inactive lifestyle. (integrative-medicine-clinics.com)
  • Asked to comment, former Obesity Society President Steven B. Heymsfield, MD, told Medscape, "Metabolically healthy obesity is sort of like a warning light - you're overweight and very lucky. (medscape.com)
  • According to the World Health Organization (WHO) report in February 16th2018, obesity has nearly tripled since 1975.According to WHO reports, in 2016, more than 1.9 billion adults, 18 years and older, were overweight, more than 650 million of which were affected by obesity. (heraldopenaccess.us)
  • It can be seen that abnormal lipid, cholesterol and glucose metabolism are consistently indicated as central in the pathophysiology, and possibly the pathogenesis of AD. (nih.gov)
  • Intermittent fasting is one of the ways to boost your metabolism and keep your metabolic health. (healthifyme.com)
  • They have almost the same efficiency for improving lipid and glucose metabolism. (healthifyme.com)
  • Saltiel, A. R. & Kahn, C. R. Insulin signalling and the regulation of glucose and lipid metabolism. (nature.com)
  • Petersen, M. C., Vatner, D. F. & Shulman, G. I. Regulation of hepatic glucose metabolism in health and disease. (nature.com)
  • The aim of this review was to summarize and discuss current knowledge on the impact of dietary fibre as modulator of the relationship between glucose metabolism and microbiota composition in humans. (springer.com)
  • More specifically, we analysed evidence from observational studies and randomized nutritional intervention investigating the relationship between gut microbiota, short-chain fatty acids and glucose metabolism. (springer.com)
  • Indeed, it may influence multiple physiological mechanisms related to human health, i.e. synthesis of micronutrients, defence against pathogens, regulation of glucose and lipid metabolism, and immune function [ 1 ]. (springer.com)
  • Therefore, in this review, we summarized current evidence from observational and intervention studies performed in humans investigating the relationship between the composition of the gut microbiota, concentration of SCFA and glucose metabolism. (springer.com)
  • This mineral might play a role in carbohydrate, lipid, and protein metabolism by potentiating insulin action. (healthiersteps.com)
  • Since its discovery, adiponectin has been identified as one of the key regulators involved in glucose and lipid metabolism. (encyclopedia.pub)
  • In addition to these, it was suggested that chronic low-grade inflammation and oxidative stress are the underlying mechanisms of PCOS-mediated metabolic consequences and might trigger cardio-metabolic risk in women with PCOS. (bvsalud.org)
  • At this point, there is substantial evidence to suggest that various non-nutrient food components modulate cardio-metabolic health together with inflammation and oxidative stress. (bvsalud.org)
  • RECENT FINDINGS: Increasing the intake of dietary polyphenols might reduce oxidative stress and inflammation and thus alleviate the risk of metabolic, endothelial, and cardiovascular disorders. (bvsalud.org)
  • Metabolic syndrome is a cluster of medical disorders that, when manifested altogether, increases the risk of developing cardiovascular disease and type 2 diabetes 6) . (e-apem.org)
  • These risk factors may lead to cardiovascular disease and type 2 diabetes. (nestle-family.com)
  • it is associated with increased risk of type-2 diabetes and cardiovascular disease. (worldhealth.net)
  • metabolic syndrome, type 2 diabetes, cardiovascular lesions and malignancies. (benthamscience.com)
  • This combination increases the risk of development of cardiovascular disease, fatty liver and type 2 diabetes. (edu.au)
  • Metabolic syndrome can increase the risk of type 2 DM and cardiovascular disease. (isainsmedis.id)
  • When you eat food, your digestive system breaks that food down into glucose which is a type of sugar. (integrative-medicine-clinics.com)
  • The levels of glucose and insulin in your blood will continue to rise, and could eventually lead to serious health problems such as type 2 diabetes. (integrative-medicine-clinics.com)
  • All of the above-mentioned disorders contribute to metabolic syndrome and are related to the development of type 2 diabetes and ischaemic heart disease. (hindawi.com)
  • If your blood sugar levels become too high, you can develop type 2 diabetes . (healthline.com)
  • Women with rosacea had a significant association with type 1 diabetes, celiac disease, multiple sclerosis and rheumatoid arthritis, when stratified by sex. (diabetestalk.net)
  • an increased blood sugar level after a period of fasting, or previously diagnosed type 2 diabetes. (mydr.com.au)
  • For some, even those with Type 2 Diabetes, intermittent fasting may not work. (healthifyme.com)
  • Cet article a pour objectif de mieux comprendre les mécanismes menant à l'insulinorésistance et au diabète de type 2, selon les plus récentes avancées dans la connaissance du rôle et des interactions d'hormones spécifiquement issues de l'adipocyte, récemment identifiées, et appelées adipocytokines ou adipokines. (erudit.org)
  • Metabolic syndrome is a cluster of conditions that occur together, increasing the risk of heart disease, NASH, and type 2 diabetes, among others. (gertitashkomd.com)
  • Moreover, the syndrome is closely linked to the development of type 2 diabetes . (gertitashkomd.com)
  • In addition, there is evidence that fatty acids interfere with very early stages of Glucose Transporter Type 4 (GLUT4) and hexokinase II activity [8]. (heraldopenaccess.us)
  • Manufacturers market chromium supplements widely in the United States for people with type 2 diabetes, and many adults use them in the hope that the supplements will reduce their risk of diabetes or improve their glycemic control. (healthiersteps.com)
  • As a consequence, there has also been a marked increase in the prevalence of type 2 diabetes all over the world and this chronic metabolic disease is now considered as a coronary heart disease risk equivalent. (researchgate.net)
  • If replicated, the association of this phenotype with more severe IR-features indicated that it may contribute to identifying of those most at risk for incident type II diabetes and cardiometabolic disease. (biomedcentral.com)
  • Background: Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. (natap.org)
  • The metabolic syndrome classification is of interest in epidemiologic studies because of its ability to predict the development of cardiovascular disease (CVD) and type 2 diabetes in adults ( 2 ). (cdc.gov)
  • In January 2013, the American Academy of Pediatrics (AAP) issued clinical practice guidelines on the management of type 2 diabetes in children and adolescents. (medscape.com)
  • The guidelines recommend insulin treatment in all patients who present with ketosis or extremely high blood glucose levels because it may not be clear initially whether these patients have type 2 or type 1 diabetes. (medscape.com)
  • Once a diagnosis of type 2 diabetes is confirmed, lifestyle modification and metformin treatment should be initiated. (medscape.com)
  • Unless an acute complication (eg, recurrent hypoglycemia, persistent ketosis, hyperglycemic hyperosmolar state) occurs or there is poor patient compliance with treatment, type 2 diabetes is usually managed in an outpatient setting. (medscape.com)
  • A study by Loimaala et al study showed that long-term endurance and strength training resulted in improved metabolic control of type 2 diabetes compared with standard treatment. (medscape.com)
  • Because type 2 diabetes in children and adolescents is strongly associated with obesity and sedentary lifestyle, any intervention designed to increase physical activity and improve dietary habits should be encouraged. (medscape.com)
  • Liraglutide, a glucagonlike peptide-1 (GLP-1) agonist, is the first noninsulin drug approved to treat type 2 diabetes in pediatric patients since metformin was approved for pediatric use in 2000. (medscape.com)
  • Specific antiretroviral therapies are known to affect individual components of the metabolic syndrome adversely, such as increasing triglycerides (lopinavir/ritonavir,32 nevirapine,33 and nelfinavir33) and increasing fasting glucose (indinavir34 and lopinavir/ritonavir35). (natap.org)
  • Green coffee with or without caffeine attenuated body weight and reduced cardiovascular disorders such blood pressure and cardiac stiffness, and improved heart and liver structure without improving glucose homeostasis or plasma lipid concentrations. (edu.au)
  • My studies show the promising potential of functional foods against life-style associated metabolic disorders. (edu.au)
  • Metabolic syndrome is a term used to describe a number of disorders that happen all at the same time. (integrative-medicine-clinics.com)
  • Metabolically healthy obesity" was defined as a BMI of 30 kg/m 2 or higher without any metabolic disorders, such as high blood pressure, increase in fasting plasma glucose, or changes in lipids, based on established cutoffs. (medscape.com)
  • Acquired or inherited defects associated to environmental factors in any part of this system can lead to metabolic disorders such as the syndrome X which is presently a frequent syndrome in industrialized countries. (erudit.org)
  • In addition, if necessary, specific treatment of the metabolic disorders is required. (erudit.org)
  • Their prevalence is higher in patients presenting cardiovascular risk factors.This review takes stock of the frequency, the mechanisms, and the implications of major cardiovascular risk factors in patients with serious mental disorders. (bvsalud.org)
  • The purpose of our study was to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) concentration and factors that characterize metabolic syndrome in Korean children and adolescents. (e-apem.org)
  • Studies of the relationship between serum vitamin D and metabolic syndrome in children are lack. (e-apem.org)
  • Thus, we investigated the association between serum 25(OH)D concentration and the components of metabolic syndrome and IR in Korean children and adolescents using data obtained from the Korean National Health and Nutrition Examination Survey (KNHANES) conducted from 2008 to 2010. (e-apem.org)
  • Here, we have reviewed recent studies concerning the role of the gut microbiota in metabolic syndrome and the effects of probiotic bacterial strains and prebiotics on the prevention or treatment of metabolic syndrome, such as their anti-obesity and anti-inflammatory effects and their ability to improve glycemic control and modulate serum lipids. (biomedcentral.com)
  • L-carnitine supplementation decreases serum glucose but has no effect on glucose oxidation [11]. (heraldopenaccess.us)
  • ABSTRACT This study assessed the prevalence of the metabolic syndrome, and its components, as defined by Adult Treatment Panel III criteria in Jordanian patients attending a family practice clinic for management of cardiovascular risk factors. (who.int)
  • "To our knowledge, this is the first clinical investigation of the effects of green tea supplementation in endogenous antioxidant markers in obese participants with the metabolic syndrome," ​wrote researchers from Oklahoma State University and the University of Oklahoma. (nutraingredients-usa.com)
  • "Significant effects were observed in both green tea beverage and extract supplementation, when compared with the control group, in elevating whole blood glutathione concentrations and plasma antioxidant capacity in obese participants with the metabolic syndrome," ​ wrote the researchers. (nutraingredients-usa.com)
  • The alarming figures on childhood obesity estimate that by 2010 almost 287 million kids will be obese, and the overall obese population could more than double to 700 million by 2015. (rejuvenation-science.com)
  • Despite a modest body weight change relative to placebo-treated mice, GW-501516 treatment also improved diabetes as revealed by the decrease in blood glucose and blood insulin levels in genetically obese animals. (umbrellalabs.is)
  • 1 Metabolic syndrome has been linked to an increased risk of diabetes as well as both atherosclerotic and non-atherosclerotic cardiovascular disease (CVDs). (org.sa)
  • Of total participants, 18% met the criteria for metabolic syndrome. (cdc.gov)
  • Even a modest increase in body weight may lead to a rather significant increase in the prevalence of cardiovascular morbidity and mortality. (kauveryhospital.com)
  • This study aimed to estimate the prevalence of cardiovascular risk factors including metabolic syndrome in adolescents aged 12 to 17 years in Brazilian cities with over 100,000 inhabitants. (bvsalud.org)
  • concurrently, these countries' populations often experience changes in diet and reductions in physical activity that lead to higher prevalence of cardiovascular disease (CVD) and CVD risk factors (3). (cdc.gov)
  • It must be noted that even a modest rise in body weight can cause a significant rise in the rate of cardiovascular morbidity and mortality. (kauveryhospital.com)
  • In this study we assessed the preva- having a first degree relative (parent, prevalence in various populations was lence of the metabolic syndrome and sibling or child) that has history of myo- hindered by lack of a uniform definition its individual components as defined cardial infarction or ischaemic stroke of the syndrome [1]. (who.int)
  • Metabolic syndrome is a group of five risk factors, that when left untreated, increase the likelihood of developing heart disease, diabetes, and stroke. (healthline.com)
  • People with MS are twice as likely to die and three times as likely to have a heart attack or stroke than people without the syndrome. (biomedcentral.com)
  • People with metabolic syndrome not only have an increased risk of heart disease, but their risk of stroke and diabetes is also higher than average. (mydr.com.au)
  • Having metabolic syndrome doubles your risk of having cardiovascular disease, such as heart attack or stroke, compared with people who don't have this syndrome. (mydr.com.au)
  • Leading to death from diabetes, heart disease, and stroke, the root cause of CMR is inadequate physical activity, a Western diet identified primarily by low intake of fruits, vegetables, and whole grains, and high in saturated fat, as well as a number of yet-to-be-identified genetic factors. (healthpartners.com)
  • The compensatory hyperinsulinemia associates with a set of metabolic features that characterize the metabolic syndrome. (biomedcentral.com)
  • Results showed that, compared to levels at the start of the study, açai ingestion was associated with significant reductions in glucose, insulin, and total cholesterol levels. (tamarindfruit.com)
  • To the best of our knowledge, short-chain fatty acids (SCFAs), bile salt hydrolase (BSH), metabolic endotoxemia and the endocannabinoid (eCB) system are essential in regulating the initiation and progression of MS through the normalization of adipogenesis and the regulation of insulin secretion, fat accumulation, energy homeostasis, and plasma cholesterol levels. (biomedcentral.com)
  • Other therapies have been associated with improvements in metabolic profiles, such as increases in HDL cholesterol (nevirapine and nelfinavir).33 In our cohort, lopinavir/ritonavir users had a higher risk of developing metabolic syndrome. (natap.org)
  • The National Cholesterol Education Program's Adult Treatment Panel III report (ATP III) identified the proinflammatory state with elevations of C-reactive protein and a prothrombotic state with increased plasma plasminogen activator inhibitor and fibrinogen as associated with the metabolic syndrome 4 . (bvsalud.org)
  • Obesity is a multifactorial disease that is currently developing a threatening tendency towards becoming the main cause of chronic disease in the world. (benthamscience.com)
  • This interconnection underscores the importance of managing metabolic syndrome to prevent the onset of this chronic metabolic disorder. (gertitashkomd.com)
  • Individuals with this syndrome face an increased likelihood of developing chronic kidney disease , emphasizing the pervasive nature of its consequences on various vital organs. (gertitashkomd.com)
  • Obesity is a chronic, multifactorial, relapsing disorder characterized by excess body weight and defined as a body mass index (BMI) of ≥ 30 kg/m2. (msdmanuals.com)
  • The ABOM stresses obesity be considered a chronic disorder that requires lifelong treatment and follow-up. (msdmanuals.com)
  • In contrast, the relation between increasing viral load and metabolic syndrome does not seem to be mediated by general inflammation caused by chronic infection for 2 reasons. (natap.org)
  • Although metabolic syndrome generally affects older people, it is possible, with increasing childhood obesity, for metabolic syndrome to affect young adults and even adolescents and children. (mydr.com.au)
  • Obesity in Adolescents Obesity is now twice as common among adolescents than it was 30 years ago and is one of the most common reasons for visits to adolescent clinics. (msdmanuals.com)
  • Pediatric obesity remains an ongoing serious international health concern affecting ~17% of US children and adolescents, threatening their adult health and longevity. (medscape.com)
  • Adolescents undergoing lifestyle therapy, medication regimens, or bariatric surgery for obesity will need cohesive planning to help them effectively transition to adult care, with continued necessary monitoring, support, and intervention. (medscape.com)
  • Metabolic syndrome is increasing among adolescents. (cdc.gov)
  • Interestingly, IFC-305 prevented alterations in glucose and insulin tolerance, enabling the regulation of glucose levels in the same way as in the control group. (bvsalud.org)
  • While awaiting the release of new drugs, topiramate, alone or combined with phentermine, has been proposed as a novel anti-obesity drug, showing relevant effects not only on weight loss but also on cardiometabolic alterations and biomarkers, even though new studies should clarify the mechanisms of these findings. (benthamscience.com)
  • However, there is a lack of knowledge in combining the probable mechanisms of dietary polyphenols on PCOS and related cardio-metabolic consequences. (bvsalud.org)
  • Thus, the effects of dietary polyphenols on PCOS and accompanying cardio-metabolic disturbances need to be discussed and evaluated with underlying mechanisms. (bvsalud.org)
  • The molecular mechanisms underlying this obesity-induced cardiac phenotype disorder are not well understood. (kauveryhospital.com)
  • Obesity is a multifactorial, highly complex medical condition involving abnormal or excessive body fat accumulation that can cause health impairment. (molvis.org)
  • Metabolic syndrome is a multifactorial disease with high prevalence worldwide. (bvsalud.org)
  • Causes of obesity are multifactorial and include genetic predisposition and behavioral, metabolic, and hormonal influences. (msdmanuals.com)
  • Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome. (worldhealth.net)
  • Moreover, the rise in "metabolically healthy" obesity occurred primarily among people aged 60 and older, men, and White adults, as well as those with higher income, private insurance, or class 1 obesity. (medscape.com)
  • Montmorency tart cherries can offer amazing health-promoting benefits for adults with metabolic syndrome, reports a new study. (medindia.net)
  • Global rates of metabolic syndrome are on the rise, and the results of the present study suggest Montmorency tart cherries, in juice or capsule form, could exert beneficial effects for adults with this condition when incorporated into an overall healthy diet," said Desai. (medindia.net)
  • Objective: To determine the incidence and risk factors for metabolic syndrome in HIV-infected adults in the Nutrition for Healthy Living (NFHL) study (2000-2003) and prevalence relative to the findings of the National Health and Nutrition Examination Survey (NHANES) (1999-2002). (natap.org)
  • Among our cohort of HIV-infected adults, the risk of developing metabolic syndrome was higher in those with a clinically relevant increase in viral load (≥0.5 log) in the previous 6 months. (natap.org)
  • Age-adjusted prevalence of diagnosed diabetes by race andethnicity, education level, family income level, metropolitan residence, and sex among adults aged 18 years or older, United States, 2019-2021. (cdc.gov)
  • Age-adjusted incidence of diagnosed diabetes among adults aged 18 years or older, United States, 2018-2019. (cdc.gov)
  • There is strong evidence that obesity leads to increased sympathetic modulation and a decreased vagal tone leading to a lack of autonomic control (characterized by reduction of heart rate variability) that can bring about changes in the renin-angiotensin-aldosterone system in alpha agonists and central alpha 2-1 and beta-adrenergic receptors. (bvsalud.org)
  • The predominance of central, viscerally deposited fat may alter the immunological, metabolic and endocrine milieu. (benthamscience.com)
  • However, many other factors appear to increase a person's predisposition to obesity, including endocrine disruptors (eg, bisphenol A [BPA]), gut microbiome, sleep/wake cycles, and environmental factors. (msdmanuals.com)
  • Endocrine etiologies for obesity are rare and usually are accompanied by attenuated growth patterns. (medscape.com)
  • The first step in the therapeutic strategy against obesity should be the correct diagnosis of its causes and the promotion of lifestyle changes including physical exercise and a healthy diet. (benthamscience.com)
  • Plant-based diets provide potential therapeutic approaches to metabolic syndrome. (edu.au)
  • Frequently, my patients inquire about the definition, significance, and available therapeutic options for metabolic syndrome. (gertitashkomd.com)
  • Despite a significant increase in research on pediatric obesity since the initial publication of these guidelines 8 years ago, further study is needed of the genetic and biological factors that increase the risk of weight gain and influence the response to therapeutic interventions. (medscape.com)
  • With these information, the researchers hope that snow peas would prove to have significant anti-obesity effects. (directcurrentmusic.com)
  • Saccharin's pod extract as an anti-obesity agent on male albino mice. (directcurrentmusic.com)
  • 2. Determine the percent anti- obesity activity of the test plant extract based on weight loss. (directcurrentmusic.com)
  • Significance of the Study If proven effective, the research study can serve as one of the basis for future searches, since not much anti-obesity agents were studied by the students of the Department of Pharmacy of the University of San Carols, Zebu City. (directcurrentmusic.com)
  • Atta-ur-Rahman, M. Iqbal Choudhary , " Anti-Obesity Drug Discovery and Development ", Bentham Science Publishers (2014). (benthamscience.com)
  • This underscores the multisystem impact of metabolic syndrome, affecting not only the cardiovascular and metabolic systems but also the liver. (gertitashkomd.com)
  • This underscores the broad impact of metabolic syndrome on different physiological functions, including those related to sleep and respiratory health. (gertitashkomd.com)
  • Coffee pulp and spent coffee considered as waste products of coffee manufacturing industries attenuated cardiovascular remodelling and non-alcoholic fatty liver disease. (edu.au)
  • Intervention with chlorogenic acid decreased body weight and visceral fat accumulation, improved heart and liver structure and function but did not improve glucose tolerance. (edu.au)
  • Fig. 4: Transfer of steatotic and metabolic phenotypes to mice through FMT of material from patients with liver steatosis grade 3. (nature.com)
  • A number of potential implications for clinical practice are derived from the cardiometabolic state underlying obesity and its comorbidities. (benthamscience.com)