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  • high
  • IP-6 Inositol Hexaphosphate by Source Naturals is a component of certain dietary fibers, particularly most cereal grains, legumes, and seeds high in oil. (evitamins.com)
  • take inositol
  • Some people take inositol by mouth for diabetes, nerve problems caused by diabetes, diabetes diagnosed during pregnancy (gestational diabetes), treating a disorder called metabolic syndrome and conditions associated with menopause and polycystic ovary syndrome (PCOS), including failure to ovulate, high blood pressure, high triglycerides, and high levels of testosterone. (webmd.com)
  • Pregnancy isn't the only health-related reason why people shouldn't take inositol. (livestrong.com)
  • If you have chronic kidney failure, do not take inositol unless otherwise instructed by a doctor. (livestrong.com)
  • In addition, people with bipolar disorder shouldn't take inositol without first talking with a doctor. (livestrong.com)
  • Lipids
  • Among different inositol lipids, the importance in transmembrane signaling and regulation of cell functions are best documented for PtdIns(4,5)P2 and PtdIns(3,4,5)P3. (springer.com)
  • There are several ways in which these low-abundance inositol lipids (less than 1 % of membrane phospholipids) could provide a signaling link or fulfill other roles in different cellular processes. (springer.com)
  • Katan M. (2015) Inositol Lipids. (springer.com)
  • Authoritative and cutting-edge, Inositol Phosphates and Lipids: Methods and Protocols compiles many of the techniques that underscore phosphorylated inositol cell biology in one convenient guide. (springer.com)
  • polycystic ovary sy
  • Taking particular forms of inositol (D-chiro-inositol or myo-inositol) by mouth seems to lower triglyceride and testosterone levels, modestly decrease blood pressure, and improve the function of the ovaries in overweight or obese women with polycystic ovary syndrome. (webmd.com)
  • According to double-blind studies enrolling over 400 people, inositol may help improve various symptoms of polycystic ovary syndrome (PCOS) , including infertility and weight gain. (portsmouthhospital.com)
  • symptoms
  • Inositol may also help reduce symptoms associated with nerve damage caused by diabetes. (livestrong.com)
  • Inositol nicotinate has been used in conventional medical practice in Great Britain for improving symptoms of poor circulation for many years, although it is usually not the preferred treatment choice. (medicinenet.com)
  • Some research suggests that taking a specific product of inositol nicotinate (Hexopal) by mouth for several weeks modestly improves symptoms of Raynaud's syndrome. (medicinenet.com)
  • While some research suggests that taking a specific inositol nicotinate product (Hexopal) by mouth for up to 3 months improves walking distance and reduces symptoms in people with this condition, other research shows conflicting results. (medicinenet.com)
  • Metabolism
  • Balla T, Guillemette G, Baukal AJ, Catt K. Metabolism of inositol 1,3,4-trisphosphate to a new tetrakisphosphate isomer in angiotensin-stimulated adrenal glomerulosa cells. (springer.com)
  • Inositol metabolism plays a role in the development of the neural tube. (nih.gov)
  • generates
  • Hydrolysis of PtdIns(4,5)P2 occurs in response to a large number of extracellular signals and generates two second messenger molecules, inositol (1,4,5) trisphosphate (Ins(1,4,5)P3) and diacylglycerol (DAG) molecules. (springer.com)
  • Obsessive-Compulsi
  • Inositol might balance certain chemicals in the body to possibly help with mental conditions such as panic disorder, depression, and obsessive-compulsive disorder. (webmd.com)
  • Inositol has also been studied for bipolar disorder , 5 panic disorder , 6,7 bulimia , 8 and obsessive-compulsive disorder , 9,10 but the evidence remains far from conclusive. (portsmouthhospital.com)
  • ITPK1
  • Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1. (nih.gov)
  • receptor
  • The inositol 1,4,5-trisphosphate (IP3)3 receptor (IP3R) are tetrameric intracellular Ca2+ release channels on the endoplasmic membrane that are activated by the ligand IP3 [ PMID: 20813840 ]. (ebi.ac.uk)
  • Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening. (ebi.ac.uk)
  • Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating. (ebi.ac.uk)
  • bipolar disorder
  • In a 6-week, double-blind study, 24 individuals with bipolar disorder received either placebo or inositol (2 g three times daily for a week, then increased to 4 g three times daily) in addition to their regular medical treatment. (portsmouthhospital.com)
  • Health professionals with the University of Pittsburgh Medical Center warn that inositol may induce manic episodes in people with bipolar disorder. (livestrong.com)
  • suggests
  • For these two reasons, inositol has been proposed as a treatment for depression, and preliminary evidence suggests that it may be helpful. (portsmouthhospital.com)
  • While some research suggests that inositol nicotinate taken by mouth may decrease cholesterol levels , others research shows that inositol nicotinate does not have an effect. (medicinenet.com)
  • Ovarian Function: Research suggests that myo-inositol may help to support healthy ovulatory activity, ovarian function, and reproductive system function. (purecapspro.com)
  • cell membranes
  • Inositol is an important part of phospholipids in cell membranes and is important for healthy cell growth and function. (vitaminworld.com)
  • Inositol is an essential component of cell membranes, and plays an important role in cell growth and function. (vitaminworld.com)
  • Inositol is a fundamental ingredient of cell membranes and is necessary for proper function of nerves brain and muscles in the body. (kogan.com)
  • Cells
  • Inositol, in its native or lipid derived forms, serves as a master building block which, when phosphorylated, leads to the construction of more than 30 unique isomeric forms that are employed in vital but diverse regulatory roles in cells. (springer.com)
  • decrease
  • Also, giving these babies inositol by mouth or intravenously (by IV) seems to decrease the risk of death, the risk of developing a condition that can cause blindness, or the risk of bleeding in the brain. (webmd.com)
  • help
  • Inositol has also been investigated for potential cancer-preventive properties, 15-22 and there is some evidence that it may help reduce the side effects of chemotherapy in women with breast cancer. (portsmouthhospital.com)
  • mood
  • As a result, inositol may support healthy mood, emotional wellness and behavior, and ease occasional nervous tension. (purecapspro.com)
  • treatment
  • Inositol is sometimes proposed as a treatment for diabetic neuropathy , but there have been no double-blind, placebo-controlled studies on this subject, and two uncontrolled studies had mixed results. (portsmouthhospital.com)
  • Levels
  • Also, the combination seems to improve blood pressure, blood sugar, and blood insulin levels better than taking myo-inositol alone. (webmd.com)
  • Inositol, unofficially referred to as "vitamin B 8 ," is present in all animal tissues, with the highest levels in the heart and brain. (portsmouthhospital.com)