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  • organ
  • As such, the development of effective strategies for preventing and treating circulatory collapse and organ injury after gut I/R is critical for the improvement of patient outcome under such conditions. (sbir.gov)
  • this may offer local and distant organ protection in hind limb IR injury. (nutritioncare.org)
  • kidney
  • Patients undergoing long-lasting, abdominal, and urogenital surgeries with risk factors such as advanced age, peripheral artery disease, diabetes mellitus, renovascular disease, and congestive heart failure are candidates for acute kidney injury (AKI) due to impaired renal perfusion and decreased functional renal reserve. (dovepress.com)
  • cytokines
  • Silver within lung tissue was persistent at 7 days post IT instillation and was associated with an elevation in cytokines: IL-2, IL-13, and TNFα and expansion of I/R injury. (rti.org)
  • Conclusions: Based on these data, IT instillation of AgNP increases circulating levels of several key cytokines, which may contribute to persistent expansion of I/R injury possibly through an impaired vascular responsiveness. (rti.org)
  • protective
  • Although we have shown that administration of rat AM plus human AMBP-1 at the beginning of reperfusion is protective, it remains unknown whether a combination of human AM and human AMBP-1 is also beneficial and, if so, whether delayed administration of AM/AMBP-1 (which is more clinically relevant) reduces gut I/R-induced mortality. (sbir.gov)
  • Puerarin has shown protective effect on injury of neural cell. (hindawi.com)
  • This study investigated the protective effects of sildenafil (SIL) and resveratrol (RSV) on ovarian ischemia-reperfusion (I/R) injury. (alliedacademies.org)
  • In addition, the protective effect of hypothermia on IR injury was investigated using a new method for in situ hypothermic perfusion (IHP). (uva.nl)
  • We aimed to investigate the protective effects of an intravenous anesthetic remifentanil in renal I/R injury in the rat in comparison with dex. (dovepress.com)
  • C57Bl
  • C) Isolated C57Bl/6 hearts were treated with A-769662 (100 μmol/L) or vehicle for 30 min prior to global no-flow ischemia (25 min) and reperfusion (30 min). (nih.gov)
  • livers
  • Liver grafts from suboptimal or extended-criteria donors are more susceptible to cold and warm I-R injury and develop more easily ITBLs than normal livers. (hindawi.com)
  • subsequent
  • Isolated AMPK inactivated kinase dead (KD) hearts were treated with A-769662 (100 μmol/L) or vehicle for 30 min during baseline aerobic perfusion, prior to global no-flow ischemia (25 min) and subsequent reperfusion (30 min) without compound. (nih.gov)
  • surgical
  • Blood samples were drawn from all animals to evaluate plasma neutrophil gelatinase-associated lipocalin (NGAL) at the beginning, 15 minutes after ischemia, 15 minutes after reperfusion, and 6 hours after the surgical procedure (T0, T1, T2, and T3, respectively). (dovepress.com)