Erwinia chrysanthemiRylazeHypersensitivityNadir serum asparaginase activityAsparagineColiIntramuscularEnzymeElsparPancreatitis300MGVincristineRegimensLiposome for injectionSodium chloride injectionDose50mgAcute lymphoblSubcutaneous injectionBevacizumabSterileDosesMedication500mgTreatmentIndiaPACLITAXELPowder for InjectionErwinasePrescription
Erwinia chrysanthemi4
- The most common side effects of asparaginase erwinia chrysanthemi (recombinant) when given in combination with chemotherapy for the treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma are abnormal liver tests, nausea, muscle and bone pain, and fatigue. (wikipedia.org)
- Its marketed products include Xyrem (sodium oxybate) oral solution, Sunosi (solriamfetol), Erwinaze (asparaginase erwinia chrysanthemi), Defitelio (defibrotide sodium), Vyxeos (daunorubicin and cytarabine) liposome for injection, and others. (pharmaceutical-technology.com)
- Hypersensitivity reactions were higher in patients who received intravenous asparaginase erwinia chrysanthemi (recombinant)-rywn. (rylazepro.com)
- They evaluated the intramuscular administration of Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) in adult and pediatric patients with acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) who developed hypersensitivity to an E. coli-derived asparaginase. (biospace.com)
Rylaze5
- RYLAZE is indicated as a component of a multi-agent chemotherapeutic regimen given by intramuscular injection for the treatment of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients 1 month or older who have developed hypersensitivity to E. coli- derived asparaginase. (rylazepro.com)
- We are excited to share these results from the Phase II/III trial of Rylaze highlighting the clinically meaningful nadir serum asparaginase activity from the Monday/Wednesday/Friday dosing regimen, which supports a new dosing schedule that aligns with current clinical practice," Dr. Rob Iannone, M.D., M.S.C.E., executive vice president, global head of research and development of Jazz said. (biospace.com)
- Talk with the healthcare team about asparaginase therapy with RYLAZE. (rylaze.com)
- RYLAZE is a prescription medicine, given by intramuscular injection, that is part of a chemotherapy regimen used to treat adults and children 1 month or older who have acute lymphoblastic leukemia (ALL), a type of blood cancer that affects the white blood cells that help fight infection, and lymphoblastic lymphoma (LBL), a type of non-Hodgkin lymphoma that also affects white blood cells. (rylaze.com)
- RYLAZE is used in patients who have had an allergic reaction to E. coli asparaginase. (rylaze.com)
Hypersensitivity3
- It may also be used to treat patients who have developed hypersensitivity (but not anaphylaxis) to L-asparaginase derived from E. coli. (canada.ca)
- Part of combination chemotherapy in the treatment of ALL and lymphoblastic lymphoma in patients who developed hypersensitivity to E. coli -derived asparaginase. (unboundmedicine.com)
- Hypersensitivity to Erwinase Powder for Injection is a contraindication. (keehealthcare.com)
Nadir serum asparaginase activity2
- The main efficacy outcome measure was demonstration of the achievement and maintenance of nadir serum asparaginase activity (NSAA) above the level of 0.1 U/mL. (wikipedia.org)
- It demonstrated that greater than 90% of patients in Cohort 1c receiving the IM dose three days per week hit nadir serum asparaginase activity (NSAA) levels greater than or equal to 0.1 IU/mL at 48 and 72 hours. (biospace.com)
Asparagine5
- Asparaginase works by breaking down the amino acid known as asparagine without which the cancer cells cannot make protein. (wikipedia.org)
- L-asparaginase works by exploiting the unusually high requirement tumor cells have for the amino acid "asparagine. (marvistavet.com)
- The enzyme L-Asparaginase destroys asparagine outside the cells forcing the cells to rely completely on what they can produce on their own. (marvistavet.com)
- When L-asparaginase destroys asparagine, ammonia is a by-product. (marvistavet.com)
- Erwinase Powder for Injection works by decreasing the inability of leukemic cells to synthesize asparagine. (keehealthcare.com)
Coli1
- Asparaginase is normally derived from E. coli bacteria. (marvistavet.com)
Intramuscular1
- Unlike other chemotherapy agents, it may be given as an intramuscular or subcutaneous injection without fear of tissue irritation. (marvistavet.com)
Enzyme4
- Asparaginase is an enzyme that is used as a medication and in food manufacturing. (wikipedia.org)
- L-asparaginase is an enzyme produced by bacteria. (marvistavet.com)
- L-asparaginase may interfere with blood clotting, may raise blood sugar levels, may raise liver enzyme blood tests, and may cause liver disease in some patients. (marvistavet.com)
- Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells. (heethealthcare.com)
Elspar3
- Pegaspargase is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had some types of allergic reactions to medications similar to pegaspargase such as asparaginase (Elspar). (medlineplus.gov)
- tell your doctor and pharmacist if you are allergic to pegaspargase, asparaginase (Elspar), any other medications, or any of the ingredients in pegaspargase injection. (medlineplus.gov)
- tell your doctor if you have or ever had pancreatitis (swelling of the pancreas), blood clots, or severe bleeding, especially if these happened during an earlier treatment with asparaginase (Elspar). (medlineplus.gov)
Pancreatitis3
- Common side effects when used by injection include allergic reactions, pancreatitis, blood clotting problems, high blood sugar, kidney problems, and liver dysfunction. (wikipedia.org)
- The use of L-asparaginase has been associated with pancreatitis . (marvistavet.com)
- Hemorrhagic or necrotizing pancreatitis have been reported with L-asparaginase class products. (rylazepro.com)
300MG1
- Soliris 300mg Injection (Eculi. (magicinepharma.com)
Vincristine1
- Toxicity of vincristine another chemotherapy agent, may be more likely if vincristine and L-asparaginase are given at the same time. (marvistavet.com)
Regimens1
- Other results showed that pediatric-inspired regimens that include asparaginase have more than doubled the length of time teens and young adults with ALL stay cancer-free compared with patients who received non-pediatric regimens in earlier studies. (rylaze.com)
Liposome for injection1
- and Vyxeos liposome for injection, a product for the treatment of adults with newly-diagnosed therapy-related acute myeloid leukemia. (bamagazine.com)
Sodium chloride injection1
- Dissolve in 1 or 2 mL of Sodium chloride Injection, USP. (canada.ca)
Dose1
- Possible reasons for the plateau in event-free survival (including type and dose of induction steroid, dropping of induction anthracycline, type and dose of asparaginase, gaps early in therapy following intensification, and overall lack of compliance in maintenance) are being explored in the latest protocol ALL '97. (ox.ac.uk)
50mg1
- Manufacturer of a wide range of products which include gemcitabine 200 mg injection, mitomycin c injection, bleomycin injection, cisplatin injection ip 50mg/50ml, bortezomin for injection 3.5mg and methotrexate injection injection usp 50mg/2ml. (aarjeyhealthcare.net)
Acute lymphobl3
- As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). (wikipedia.org)
- One of the primary concerns in acute lymphoblastic leukemia treatment is the occurrence of adverse events (AEs) associated with asparaginase therapy. (wikipedia.org)
- Erwinase Powder for Injection is used for Acute lymphoblastic leukemia and other conditions. (keehealthcare.com)
Subcutaneous injection1
- It is given by subcutaneous injection every 2 weeks. (medscape.com)
Bevacizumab2
- Offering you a complete choice of products which include bevacizumab injection 100mg, paclitaxel 30 mg injection, paclitaxel 100 mg injection, paclitaxel 260mg injection, taxonab paclitaxel protein bound particles for injectable suspension 100mg and velcade bortezomib injection. (pharmatone.in)
- Bevacizumab (100mg/4ml) injection is an anticancer medicine that is used alone or in combination with other medicines for the treatment of various types of cancers such as colorectal cancer, glioblastoma multiforme, renal cell carcinoma, cervical cancer, ovarian cancer, etc. (pharmatone.in)
Sterile1
- These Pharmaceutical Injections are hygienic, safe and sterile. (tradeindia.com)
Doses1
- After an ALL or LBL diagnosis, scheduling all treatments and going to all appointments is important to help ensure asparaginase doses are not missed. (rylaze.com)
Medication2
- Paclitaxel 30 mg Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer. (pharmatone.in)
- Erwinase Powder for Injection may also be used for purposes not listed in this medication guide. (keehealthcare.com)
500mg1
- In addition of this, they are available in varied type that include Rotarix Oral, Influvac Suspension, Cyramza 500mg, Simponi 100 mg and Ixempra 45mg injections. (tradeindia.com)
Treatment2
- Cizumab 100 mg/4ml Injection is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer and cervical cancer. (pharmatone.in)
- Treatment of CSVT resulting from L-asparaginase-induced antithrombin deficiency includes general supportive measures, anticonvulsants for seizures, and anticoagulation. (africadelight.com)
India1
- Pioneers in the industry, we offer artesunate injection ip 60 mg from India. (fourwaypharmallp.com)
PACLITAXEL14
- TMR's report on the global Paclitaxel Injection Market studies the past as well as the current growth trends and opportunities to gain valuable insights of the indicators of the market during the forecast period from 2023 to 2031. (giiresearch.com)
- The report provides revenue of the global Paclitaxel Injection Market for the period 2017-2031, considering 2023 as the base year and 2031 as the forecast year. (giiresearch.com)
- The report also provides the compound annual growth rate (CAGR %) of the global Paclitaxel Injection Market from 2023 to 2031. (giiresearch.com)
- Secondary research involved referring to key players' product literature, annual reports, press releases, and relevant documents to understand the Paclitaxel Injection Market. (giiresearch.com)
- Analysts employed a combination of top-down and bottom-up approaches to study various attributes of the global Paclitaxel Injection Market. (giiresearch.com)
- Moreover, the report throws light on the changing competitive dynamics in the global Paclitaxel Injection Market. (giiresearch.com)
- These serve as valuable tools for existing market players as well as for entities interested in participating in the global Paclitaxel Injection Market. (giiresearch.com)
- The report delves into the competitive landscape of the global Paclitaxel Injection Market. (giiresearch.com)
- Key players operating in the global Paclitaxel Injection Market have been identified and each one of these has been profiled in terms of various attributes. (giiresearch.com)
- Company overview, financial standings, recent developments, and SWOT are the attributes of players in the global Paclitaxel Injection Market profiled in this report. (giiresearch.com)
- What are the opportunities in the global Paclitaxel Injection Market? (giiresearch.com)
- The comprehensive report on the global Paclitaxel Injection Market begins with an overview, followed by the scope and objectives of the study. (giiresearch.com)
- The report analyzes the global Paclitaxel Injection Market in terms of product, end-user, and region. (giiresearch.com)
- Such valuable insights enable market stakeholders in making informed business decisions for investment in the global Paclitaxel Injection. (giiresearch.com)
Powder for Injection9
- Erwinase Powder for Injection contains Asparaginase as an active ingredient. (keehealthcare.com)
- The following is a list of possible side-effects that may occur from all constituting ingredients of Erwinase Powder for Injection. (keehealthcare.com)
- Erwinase Powder for Injection may also cause side-effects not listed here. (keehealthcare.com)
- Before using Erwinase Powder for Injection, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc. (keehealthcare.com)
- If you use other drugs or over the counter products at the same time, the effects of Erwinase Powder for Injection may change. (keehealthcare.com)
- Is Erwinase Powder for Injection safe to use when pregnant? (keehealthcare.com)
- Is Erwinase Powder for Injection safe while breastfeeding? (keehealthcare.com)
- If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Erwinase Powder for Injection medicine then it may not be safe to drive a vehicle or operate heavy machinery. (keehealthcare.com)
- Please check for these effects on your body when using Erwinase Powder for Injection. (keehealthcare.com)
Erwinase3
- ERWINASE (Erwinia L-asparaginase) Batch CAMR-180G. (canada.ca)
- ERWINASE (Erwinia L-asparaginase) for Injection is indicated in the therapy of patients with acute lymphocytic leukemia (ALL) where it is used primarily in combination with other antineoplastic agents to induce remission in children and adults with this disease. (canada.ca)
- ERWINASE for Injection should not be used as the sole agent for induction unless combination therapy is considered inappropriate. (canada.ca)
Prescription1
- Hamsyl 3750 IU (Peg L Asparaginase) is a prescription drug used to treat blood cancer (Acute lymphocytic leukemia) and Hodgkin's disease. (mbapharmaceuticals.com)