Loading...
  • 1997
  • Behavioral studies show that block of endogenous opioid action using naltrexone, a nonselective opioid antagonist, diminishes ethanol consumption ( Herz, 1997 ), and this antagonist is currently used in the treatment of alcohol dependence in humans ( Froehlich, 1996 ). (aspetjournals.org)
  • absent
  • 4 These sympathoexcitatory effects of insulin are prevented by lesion of the anteroventral third ventricle region, 9 are attenuated by ICV administration of a phosphoinositol 3 kinase inhibitor 10 or angiotensin II type I (AT 1 ) receptor antagonist losartan, 11 and are absent in melanocortin-4 receptor deficient mice. (ahajournals.org)
  • synaptic
  • We aimed, therefore, to investigate the spinal synaptic mechanisms activated by lidocaine injections in the RVM. (readbyqxmd.com)
  • The changes in the activity of GAD were accompanied by alterations in [3H]GABA binding to synaptic membranes: GABA binding was significantly elevated in the olfactory bulbs and the substantia nigra, but it was markedly reduced in the pons. (muscimol.xyz)
  • recombinant
  • A single injection of recombinant IFN-γ into the cerebrospinal fluid of IFN-γ knockout mice, however, restored the animals' social preferences by 24 hours post-injection. (jax.org)
  • behavioral
  • Chorea and other behavioral abnormalities may be induced by local disruptions of γ-aminobutyric acid (GABA) transmission in the indirect pathway. (physiology.org)
  • amplitudes
  • Injection of 2-AEMP slightly attenuated b-wave amplitudes around -3.2 log sc td s, and the attenuation increased up to b-wave saturation (-0.9 log sc td s) with 31±9% reduction at 110 ms, and 25±9% for peak to trough. (arvojournals.org)
  • Pretreatment
  • Pretreatment with phaclofen and bicuculline 20 min before morphine administration had no effect on GABA and GLU release for 100 min. (ac.ir)
  • If this is the case, pretreatment with this drug should reduce the amount of swelling after injection of kaolin and carrageenan. (aspetjournals.org)
  • upon injection
  • Exosomes - Induction of a proliferative response upon injection of exosomes was cell-line dependent with some cells inducing a significant increase in PCNA positive cells and others showing no difference compared to PBS-injections. (arvojournals.org)
  • GABAergic
  • GABA plays a major role in information processing in the GPe since roughly 80% of all synapses within this nucleus are GABAergic ( Kita 2007 ). (physiology.org)
  • concentration
  • Our results showed that morphine increased the average concentration of GABA and decreased the concentration of GLU within mPFC. (ac.ir)