Insulin, Long-ActingInsulinReceptor, InsulinInsulin ResistanceInsulin Receptor Substrate ProteinsGlucoseInsulin AntibodiesHypoglycemic AgentsInsulin AntagonistsIslets of LangerhansInsulin LisproGlucose Tolerance TestDiabetes Mellitus, Type 2Insulin Infusion SystemsGlucose Clamp TechniqueInsulin AspartInsulin, IsophaneInsulin, Regular, PorkHyperinsulinismAdipose TissueInsulin-Secreting CellsInsulinsGlucagonObesityInsulin, Regular, HumanC-PeptideProinsulinSignal TransductionFastingBlood GlucoseLiverHyperglycemiaMuscle, SkeletalDiabetes Mellitus, Type 1PhosphorylationFatty Acids, NonesterifiedAdipocytesGlucose Transporter Type 4HypoglycemiaInsulin, Short-ActingDiabetes Mellitus, ExperimentalDiabetes MellitusCells, CulturedGlucose IntoleranceKineticsInsulin-Like Growth Factor ILeptinBody WeightPhosphoproteinsDeoxyglucosePhosphatidylinositol 3-KinasesTriglyceridesMonosaccharide Transport ProteinsTime FactorsRats, WistarCell LineDose-Response Relationship, DrugProto-Oncogene Proteins c-aktHomeostasisInsulinomaBiphasic InsulinsGlycogenHemoglobin A, GlycosylatedAdiponectinRNA, MessengerPostprandial PeriodLipidsRats, Sprague-DawleyPancreasGene Expression RegulationGlucagon-Like Peptide 1Mice, Inbred C57BLRats, Inbred StrainsBody Mass IndexDietary FatsLipid MetabolismMice, ObeseMetforminMolecular Sequence DataThiazolidinedionesMuscle ProteinsMice, KnockoutLipolysis3T3-L1 CellsBiological TransportReceptor, IGF Type 1EatingRats, ZuckerMetabolic Syndrome XTolbutamideInfusions, SubcutaneousModels, BiologicalReference ValuesDietary CarbohydratesEnzyme ActivationDiet, High-FatBody CompositionStreptozocinSomatostatinEnergy Metabolism