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  • viral DNA replication
  • An in planta trans-replication system [ 5 ] was utilised to investigate the impact of Nicotiana benthamiana retinoblastoma-related (NbRBR1) and proliferating cell nuclear antigen (NbPCNA) genes, (which code for a repressor of cell cycle and the sliding clamp of host DNA replicase, respectively), on viral DNA replication. (springer.com)
  • The virus is often challenged with a quiescent cell environment, and since efficient viral DNA replication depends on S-phase factors, LT has evolved mitogenic properties. (asm.org)
  • coli
  • We have mobilized the 7.6 Kbp plasmid from P. oshimae in E. coli by introducing origin-containing transposons and described the plasmid in terms of its nucleotide sequence, copy number in the native host, mode of replication, and transcriptional start sites of the encoded ORFs. (hindawi.com)
  • vitro
  • A pattern of infection mainly observed in vitro refers to a chronic infection that is characterized by a permanent virus production in cells that are not harmed by virus replication. (biomedcentral.com)
  • novel
  • Thus, by using the novel approach for network analysis, ICF , we predict that in the T cell line chronically infected with SIV, cellular processes that are known to be crucial for early phases of HIV/SIV replication are altered and cellular responses that result in cell death are modulated. (biomedcentral.com)
  • cellular
  • They need to reprogramme host cellular machinery for DNA replication. (springer.com)
  • These results suggest that the cellular machinery for DNA replication in differentiated tissues of older leaves cannot be reprogrammed by Rep alone but may need other uncharacterised viral and plant factors. (springer.com)