Cell ProliferationApoptosisCells, CulturedSignal TransductionCell Line, TumorCell DivisionCell SurvivalCell CycleCaspasesApoptosis Regulatory ProteinsCaspase 3Cell DifferentiationProto-Oncogene Proteins c-bcl-2Cell LineInhibitor of Apoptosis ProteinsTumor Cells, CulturedBlotting, WesternIn Situ Nick-End LabelingRNA, MessengerFlow CytometryMice, Inbred C57BLImmunohistochemistryPhosphorylationEnzyme ActivationLymphocyte ActivationDNA FragmentationReverse Transcriptase Polymerase Chain ReactionRNA, Small InterferingCell MovementDown-RegulationBromodeoxyuridineTumor Suppressor Protein p53TransfectionDose-Response Relationship, Drugbcl-2-Associated X ProteinMice, KnockoutGene Expression Regulation, NeoplasticProto-Oncogene ProteinsT-LymphocytesGene Expression RegulationTime FactorsUp-RegulationKi-67 AntigenAntineoplastic AgentsEnzyme InhibitorsEpithelial CellsProliferating Cell Nuclear AntigenProto-Oncogene Proteins c-aktX-Linked Inhibitor of Apoptosis ProteinMice, TransgenicFibroblastsGene ExpressionStem CellsRNA InterferenceMice, NudeCell Growth ProcessesCaspase 9Transcription FactorsCaspase InhibitorsApoptosis Inducing FactorMitochondriaCASP8 and FADD-Like Apoptosis Regulating ProteinMice, Inbred BALB CMolecular Sequence DataFas Ligand ProteinDNA-Binding ProteinsCaspase 8Protein-Serine-Threonine KinasesCell Countbcl-X ProteinRats, Sprague-DawleyCyclin D1Muscle, Smooth, VascularCyclin-Dependent Kinase Inhibitor p21Models, BiologicalCell DeathDisease Models, AnimalCell Cycle ProteinsMitogen-Activated Protein KinasesMutationNeoplasm ProteinsDNACell Transformation, NeoplasticCytochromes cProto-Oncogene Proteins c-mycRecombinant ProteinsExtracellular Signal-Regulated MAP KinasesAnnexin A5Phosphatidylinositol 3-KinasesCyclin-Dependent Kinase Inhibitor p27MAP Kinase Signaling SystemThymidineBase SequenceReactive Oxygen SpeciesGene Knockdown TechniquesTumor Necrosis Factor-alphaNuclear ProteinsTumor Suppressor ProteinsNF-kappa BMyocytes, Smooth Muscle