Inhibits the phosphorylation aurora kinases. Medical search. Frequent questions

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Anatomy23

Cell Line, Tumor Spindle Apparatus Cell Line HeLa Cells Kinetochores Cells, Cultured Centrosome Microtubules Tumor Cells, Cultured Blastodisc 3T3 Cells Cell Nucleus Centromere Fibroblasts Microtubule-Organizing Center Cell Membrane HEK293 Cells Chromosomes Oocytes Cytoplasm COS Cells Cytosol CHO Cells

Organisms11

Potoroidae Rats, Sprague-Dawley Mice, Nude Cattle Cricetinae Mice, Knockout Mice, Inbred C57BL Rabbits Cercopithecus aethiops Saccharomyces cerevisiae Saccharomycetales

Diseases5

Polyploidy Chondroma Neoplasms Cell Transformation, Neoplastic Aneuploidy

Chemicals and Drugs144

Aurora Kinases Aurora Kinase A Aurora Kinase B Aurora Kinase C Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Protein Kinases Phosphatidylinositol 3-Kinases Serine Protein Kinase C Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Tyrosine Cyclic AMP-Dependent Protein Kinases Protein-Tyrosine Kinases Phosphoproteins Cell Cycle Proteins Mitogen-Activated Protein Kinase 1 Enzyme Inhibitors p38 Mitogen-Activated Protein Kinases Phosphoserine Threonine Piperazines Mitogen-Activated Protein Kinase 3 Casein Kinase II CDC2 Protein Kinase Azepines Mitogen-Activated Protein Kinases Organophosphates Benzamides Proto-Oncogene Proteins c-akt Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Histones Proto-Oncogene Proteins Extracellular Signal-Regulated MAP Kinases Glycogen Synthase Kinase 3 Cyclin-Dependent Kinases Microtubule-Associated Proteins RNA, Small Interfering Phosphotyrosine Intracellular Signaling Peptides and Proteins Pyrimidines p21-Activated Kinases Casein Kinases Ribosomal Protein S6 Kinases Nuclear Proteins Antineoplastic Agents Recombinant Proteins Phosphothreonine MAP Kinase Kinase Kinases Isoenzymes Phosphoprotein Phosphatases Aneugens eIF-2 Kinase Recombinant Fusion Proteins MAP Kinase Kinase 1 Pyrazoles Chromosomal Proteins, Non-Histone Tetradecanoylphorbol Acetate Calcium Quinazolines Phosphotransferases (Alcohol Group Acceptor)Phosphopeptides Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases DNA-Binding Proteins Ribosomal Protein S6 Kinases, 90-kDa Receptor Protein-Tyrosine Kinases Protein Kinase C-delta MAP Kinase Kinase 4 Adaptor Proteins, Signal Transducing rho-Associated Kinases Collagen Type XI I-kappa B Kinase RNA, Messenger Protein Kinase C-alpha Creatine Kinase AMP-Activated Protein Kinases Cyclic AMP Adenosine Triphosphate Carrier Proteins Pyruvate Kinase Proteins Myosin-Light-Chain Kinase TOR Serine-Threonine Kinases CDC2-CDC28 Kinases Pyridines Janus Kinase 2 Protein Phosphatase 1 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Imidazoles Cyclin-Dependent Kinase 5 Transcription Factors Androstadienes Okadaic Acid Membrane Proteins Casein Kinase I Thymidine Kinase 1-Phosphatidylinositol 4-Kinase Chromones Saccharomyces cerevisiae Proteins Flavonoids Indoles Morpholines Cyclin-Dependent Kinase 2 Cyclin B1 Insulin Tumor Suppressor Protein p53 Ribosomal Protein S6 Kinases, 70-kDa Myosin Light Chains Epidermal Growth Factor Protein Phosphatase 2 Protein Kinase C-epsilon 3-Phosphoinositide-Dependent Protein Kinases Cyclic GMP-Dependent Protein Kinases Receptor, Epidermal Growth Factor Staurosporine 14-3-3 Proteins Diacylglycerol Kinase Trans-Activators Protein Kinase C beta Proto-Oncogene Proteins pp60(c-src)Focal Adhesion Kinase 2 NF-kappa B Mitogen-Activated Protein Kinase 8 Vanadates MAP Kinase Kinase 2 Neoplasm Proteins Phosphoric Monoester Hydrolases Actins Phosphorus Radioisotopes Antibodies, Phospho-Specific MAP Kinase Kinase Kinase 1 Thiazoles DNA Primers Proto-Oncogene Proteins c-fyn Insulin Receptor Substrate Proteins Maleimides Tumor Suppressor Proteins Butadienes Xenopus Proteins Cytoskeletal Proteins Peptides

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Blotting, Western Transfection Models, Biological Immunoblotting Peptide Mapping Precipitin Tests Mutagenesis, Site-Directed Electrophoresis, Polyacrylamide Gel Microscopy, Fluorescence Xenograft Model Antitumor Assays Reverse Transcriptase Polymerase Chain Reaction Immunoprecipitation Sequence Alignment Amino Acid Substitution Immunohistochemistry Models, Molecular Molecular Targeted Therapy Drug Screening Assays, Antitumor Cloning, Molecular

Phenomena and Processes55

Phosphorylation Mitosis MAP Kinase Signaling System Enzyme Activation Amino Acid Sequence Protein Binding Mutation Chromosome Segregation Apoptosis Kinetochores Cell Cycle Signal Transduction Oxidative Phosphorylation Cell Proliferation Transfection Kinetics M Phase Cell Cycle Checkpoints Binding Sites Cytokinesis Protein Structure, Tertiary Polyploidy Cell Cycle Checkpoints Substrate Specificity Protein Processing, Post-Translational RNA Interference Anaphase Dose-Response Relationship, Drug Gene Expression Regulation, Enzymologic Cell Division Time Factors Base Sequence Cell Survival Protein Transport Down-Regulation Gene Expression Regulation Sequence Homology, Amino Acid Cell Physiological Processes G2 Phase Centromere Drug Synergism Transcription, Genetic Meiosis Gene Expression Regulation, Neoplastic Up-Regulation Ploidies Drug Resistance, Neoplasm Gene Expression Molecular Weight Amino Acid Substitution Amino Acid Motifs Catalytic Domain Chromosomes src Homology Domains Aneuploidy Cell Movement

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Amino Acid Sequence Molecular Sequence Data Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Aurora Kinases Aurora Kinase A Aurora Kinase B Aurora Kinase C Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Protein Kinases Phosphorylation Phosphatidylinositol 3-Kinases Mitosis Serine MAP Kinase Signaling System Protein Kinase C Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Tyrosine Cyclic AMP-Dependent Protein Kinases Cell Line, Tumor Protein-Tyrosine Kinases Enzyme Activation Phosphoproteins Amino Acid Sequence Molecular Sequence Data Spindle Apparatus Cell Line Cell Cycle Proteins Mitogen-Activated Protein Kinase 1 Enzyme Inhibitors Protein Binding Mutation p38 Mitogen-Activated Protein Kinases Chromosome Segregation Phosphoserine HeLa Cells Threonine Piperazines Blotting, Western Mitogen-Activated Protein Kinase 3 Apoptosis Casein Kinase II Kinetochores Cell Cycle CDC2 Protein Kinase Azepines Signal Transduction Mitogen-Activated Protein Kinases Organophosphates Benzamides Cells, Cultured Proto-Oncogene Proteins c-akt Oxidative Phosphorylation Mitogen-Activated Protein Kinase Kinases Cell Proliferation JNK Mitogen-Activated Protein Kinases Histones Transfection Kinetics Proto-Oncogene Proteins Extracellular Signal-Regulated MAP Kinases Glycogen Synthase Kinase 3 M Phase Cell Cycle Checkpoints Cyclin-Dependent Kinases Microtubule-Associated Proteins RNA, Small Interfering Phosphotyrosine Intracellular Signaling Peptides and Proteins Pyrimidines Binding Sites p21-Activated Kinases Centrosome Cytokinesis Casein Kinases Ribosomal Protein S6 Kinases Protein Structure, Tertiary Polyploidy Nuclear Proteins Models, Biological Microtubules Antineoplastic Agents Recombinant Proteins Phosphothreonine MAP Kinase Kinase Kinases Isoenzymes Phosphoprotein Phosphatases Chondroma Aneugens Cell Cycle Checkpoints Substrate Specificity eIF-2 Kinase Recombinant Fusion Proteins Protein Processing, Post-Translational MAP Kinase Kinase 1 Immunoblotting Pyrazoles Chromosomal Proteins, Non-Histone Peptide Mapping Tumor Cells, Cultured RNA Interference Tetradecanoylphorbol Acetate Anaphase

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