Oxidative StressCell DeathApoptosisAntineoplastic Combined Chemotherapy ProtocolsCaspasesProto-Oncogene Proteins c-bcl-2bcl-2 Homologous Antagonist-Killer ProteinMitochondriaChemotherapy, Adjuvantbcl-2-Associated X ProteinApoptosis Regulatory Proteinsbcl-X ProteinSignal TransductionCell LineReactive Oxygen SpeciesCause of DeathAntioxidantsAntineoplastic AgentsProto-Oncogene ProteinsHydrogen PeroxideCisplatinCombined Modality TherapyCell SurvivalDoxorubicinTime FactorsTreatment OutcomeCyclophosphamideGlutathioneLipid PeroxidationSuperoxide DismutaseOxidantsCell Line, TumorCells, CulturedDeathEtoposideBreast NeoplasmsCaspase 3Dose-Response Relationship, DrugNeoadjuvant TherapySurvival AnalysisMalondialdehydePrognosisNecrosisDisease-Free SurvivalNeuronsSurvival RateCatalaseLung NeoplasmsNeoplasm StagingNeoplasmsDrug Administration ScheduleOxidation-ReductionDNA FragmentationPhotic StimulationThiobarbituric Acid Reactive SubstancesAutophagyPaclitaxelRats, Sprague-DawleyMice, Inbred C57BLProtein CarbonylationDrug Resistance, NeoplasmMethotrexateIn Situ Nick-End LabelingBlotting, WesternEnzyme ActivationGlutathione PeroxidaseDisease Models, AnimalDNA DamageAcetylcysteineCarboplatinVinblastineFollow-Up StudiesModels, BiologicalParaquatInduction ChemotherapyTaxoidsNeoplasm Recurrence, LocalRNA, MessengerImmunohistochemistryMutationEnzyme InhibitorsBleomycinAntineoplastic Agents, PhytogenicCaspase InhibitorsMice, KnockoutMembrane Potential, MitochondrialCytoprotectionAntimetabolites, AntineoplasticAnalysis of Variancetert-ButylhydroperoxideIfosfamideTumor Cells, CulturedF2-IsoprostanesRats, WistarDeoxyguanosineBiological MarkersDeoxycytidineFree Radical ScavengersOrganoplatinum CompoundsAntineoplastic Agents, Alkylating