GliomaCell CycleBrain NeoplasmsCell Cycle ProteinsCell Line, TumorGlioblastomaTumor Cells, CulturedApoptosisCell Cycle CheckpointsCell DivisionCell ProliferationG1 PhaseSignal TransductionTransfectionGene Expression Regulation, NeoplasticRNA, MessengerMitosisCell LineBlotting, WesternAstrocytomaS PhaseCyclinsMolecular Sequence DataPhosphorylationTumor Suppressor Protein p53RNA, Small InterferingCell SurvivalG2 PhaseGene ExpressionMutationDNA-Binding ProteinsProtein-Serine-Threonine KinasesTranscription FactorsReverse Transcriptase Polymerase Chain ReactionCells, CulturedCyclin-Dependent Kinase Inhibitor p21Mice, NudeFlow CytometryDown-RegulationImmunohistochemistryBase SequenceNeoplasm InvasivenessUp-RegulationCyclin-Dependent Kinase Inhibitor p27Gene Expression RegulationNuclear ProteinsCyclin D1Retinoblastoma ProteinPromoter Regions, GeneticMenstrual CycleTumor Suppressor ProteinsG2 Phase Cell Cycle CheckpointsTime FactorsAntineoplastic AgentsRNA InterferenceAmino Acid SequenceTranscription, GeneticMice, TransgenicProto-Oncogene ProteinsCell NucleusCell MovementG1 Phase Cell Cycle CheckpointsCell DifferentiationG0 PhaseProtein BindingDNA DamageModels, BiologicalNeoplasm ProteinsCarrier ProteinsHeLa CellsEnzyme ActivationNeoplasm TransplantationPhenotypeAdenoviridaeGene Expression ProfilingCyclin EAntineoplastic Agents, AlkylatingEnzyme InhibitorsDacarbazineCyclin-Dependent Kinase 2CDC2 Protein KinaseGene Knockdown TechniquesProto-Oncogene Proteins c-bcl-2Cyclin-Dependent Kinase 4Cyclin BOptic Nerve GliomaRecombinant Fusion ProteinsAstrocytesCyclin ADNA ReplicationGenetic VectorsSaccharomyces cerevisiaeXenograft Model Antitumor AssaysMembrane ProteinsDNA PrimersMicrotubule-Associated ProteinsProto-Oncogene Proteins c-aktImmunoblottingGenes, cdcDNA