Cell CycleCell Line, TumorApoptosisCell Cycle ProteinsTumor Cells, CulturedCell DivisionCell ProliferationTumor Suppressor Protein p53Signal TransductionCell SurvivalCell Cycle CheckpointsCaspasesCell LineApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Cells, CulturedTumor Necrosis Factor-alphaAntineoplastic AgentsG1 PhaseFlow CytometryTumor Markers, BiologicalRNA, MessengerTumor Suppressor ProteinsBlotting, WesternInhibitor of Apoptosis ProteinsTransfectionGene Expression Regulation, NeoplasticNeoplasmsNeoplasms, ExperimentalTumor BurdenPhosphorylationMice, NudeMitosisMolecular Sequence DataTime FactorsCyclinsNeoplasm ProteinsS PhaseRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionDown-RegulationCyclin-Dependent Kinase Inhibitor p21MutationDNA FragmentationIn Situ Nick-End LabelingProtein-Serine-Threonine KinasesImmunohistochemistryProto-Oncogene ProteinsEnzyme ActivationXenograft Model Antitumor Assaysbcl-2-Associated X ProteinCell Growth ProcessesDNA-Binding ProteinsDose-Response Relationship, DrugGenes, Tumor SuppressorNeoplasm TransplantationBreast NeoplasmsG2 PhaseMice, Inbred BALB CMice, Inbred C57BLColonic NeoplasmsBase SequenceDNA DamageTranscription FactorsEnzyme InhibitorsCell Transformation, NeoplasticRetinoblastoma ProteinNeoplasm MetastasisModels, BiologicalAdenocarcinomaHeLa CellsTransplantation, HeterologousUp-RegulationGene ExpressionMammary Neoplasms, ExperimentalCyclin-Dependent Kinase Inhibitor p27Gene Expression RegulationNeovascularization, PathologicCell NucleusBrain NeoplasmsCell DifferentiationMitochondriaFibroblastsAmino Acid SequenceTranscription, GeneticX-Linked Inhibitor of Apoptosis ProteinRNA InterferenceCarcinoma, Ehrlich TumorDNA, NeoplasmCaspase 9Cell DeathCyclin D1G2 Phase Cell Cycle CheckpointsMice, SCIDNuclear ProteinsCarrier ProteinsAntigens, NeoplasmProtein BindingWilms Tumor