Vascular Endothelial Growth Factor ACell MovementNeovascularization, PhysiologicEndothelial CellsEndothelium, VascularCells, CulturedVascular Endothelial Growth Factor Receptor-2Signal TransductionEndothelial Growth FactorsVascular Endothelial Growth FactorsPhosphorylationLymphokinesCell ProliferationEnzyme InhibitorsNeovascularization, PathologicCattleCell LineTosylphenylalanyl Chloromethyl KetoneNerve BlockCell Line, TumorAnimal MigrationDose-Response Relationship, DrugEnzyme ActivationCell Migration InhibitionProtease InhibitorsForeign-Body MigrationCysteine Proteinase InhibitorsHeart BlockDipeptidesCysteine EndopeptidasesRNA, MessengerSulfonesApoptosisMolecular Sequence DataBlotting, WesternProtein BindingHIV Protease InhibitorsRats, Sprague-DawleyMitogen-Activated Protein KinasesMice, Inbred C57BLTransfectionCell DivisionProtein Kinase InhibitorsTime FactorsTumor Cells, CulturedIndolesProtein-Serine-Threonine KinasesProteasome Endopeptidase ComplexReceptors, Vascular Endothelial Growth FactorCell AdhesionNF-kappa BMembrane ProteinsAmino Acid SequenceKineticsProtein Kinase CMultienzyme ComplexesVascular Endothelial Growth Factor Receptor-1Protein-Tyrosine KinasesBiological TransportProto-Oncogene ProteinsCell Migration AssaysChemotaxisMacrophage Migration-Inhibitory FactorsDNA-Binding ProteinsHydrolysisTumor Necrosis Factor-alphaWound HealingHuman MigrationTransendothelial and Transepithelial MigrationReceptors, Growth FactorChemotaxis, LeukocyteNeoplasm InvasivenessImmunohistochemistryRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionAngiogenesis InhibitorsEmigration and ImmigrationNeuropilin-1Receptor Protein-Tyrosine KinasesBundle-Branch BlockChemokine CXCL12Mice, KnockoutCell DifferentiationModels, Biologicalrac1 GTP-Binding ProteinActinsUp-RegulationIntercellular Signaling Peptides and ProteinsCell Migration Assays, LeukocytePseudopodiaIntegrinsGene Expression RegulationUmbilical VeinsFibronectinsRNA InterferenceHypoxia-Inducible Factor 1, alpha SubunitMutationRecombinant ProteinsBase SequenceGene Expression Regulation, Neoplastic