Inhibitors actin myosin skeletal muscle contractions. Medical search. Frequent questions

Myosin filaments act as molecular motors and by binding to actin enables filament sliding. (wikipedia.org)
The ACTA1 gene encodes skeletal muscle alpha-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. (qxmd.com)
Smooth muscle contains thick and thin filaments that do not arrange into sarcomeres, resulting in a non-striated pattern. (statpearls.com)
Actin filaments attach to dense bodies spread throughout the cell. (statpearls.com)
2. Calcium activated sarcomeric myosin S1 ATPase assays with tropomyosin/troponin coated F-actin (thin filaments) as substrate. (cytoskeleton.com)
Myosin light chain kinase (facilitates myosin interaction with actin filaments to produce contractile activity), protein kinase C, and the -secretase complex also were identified as targets. (nih.gov)
We present evidence that Ozz binding to the embryonic myosin isoform within sarcomeric thick filaments marks it for ubiquitination and proteolytic degradation allowing its alternative with neonatal or adult isoforms. (immune-source.com)
Beads coated with actin-related protein 2/3 (Arp2/3)-activating proteins can induce two distinct types of actin organization in cytoplasmic extracts: (1) comet tails or clouds displaying a dendritic array of actin filaments and (2) stars with filament bundles radiating from the bead. (silverchair.com)
We propose a model for filopodial formation in which actin filaments of a preexisting dendritic network are elongated by inhibition of capping and subsequently cross-linked into bundles by fascin. (silverchair.com)

Actin and myosin act as the main proteins involved in muscle contraction. (statpearls.com)
Cellular forces, such as the tension generated by the contraction of the actomyosin cortex, establishes polarity by facilitating the clustering of polarity (PAR) proteins and passively transporting these proteins clusters to one side of the cell along with the cortical flow. (mechanobio.info)
This study proposes a mechanically-driven cell polarization process: the tension generated from the contraction of the actomyosin cortex facilitates the clustering of the polarity proteins PAR3 and PKC3 into high-intensity clusters at the cortex. (mechanobio.info)
Although it contains three of the EF-hand domains common to Actin and other Myosin regulating proteins, MYL6B does not bind calcium during contraction. (scbio.cn)
Many sarcomeric proteins are developmentally expressed as a series of isoforms leading at maturation to patterns appropriate for slower or fast contraction and aerobic or anaerobic metabolism. (immune-source.com)
In skeletal muscles ubiquitination of muscle mass proteins to target them to get proteolysis is an important component of cachexia and Indigo muscle mass atrophy [6] [7]. (immune-source.com)
Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. (thermofisher.com)
Actins are highly conserved proteins that are involved in cell motility, structure and integrity. (thermofisher.com)
Using purified proteins, we showed that a small number of components are sufficient for the assembly of filopodia-like bundles: Wiskott-Aldrich syndrome protein (WASP)-coated beads, actin, Arp2/3 complex, and fascin. (silverchair.com)

Cytoskeleton, Inc. is a reliable source of compound screening services for kinesin and myosin targeted projects. (cytoskeleton.com)
A filamentous actin cytoskeleton was required, and responses were mirrored by changes to actin remodeling rates and visual evidence of stretch-induced actin depolymerization. (nature.com)
Fiber cell integrity was assessed by analyzing the actin cytoskeleton as well as the expression of aquaporin-0 (AQP0). (molvis.org)
NO-induced cGMP signaling modulated RhoA/ROCK signaling in platelets, leading to the disinhibition of MLCP to control the phosphorylation of MLC and remodeling of platelet actin cytoskeleton. (cusabio.com)
In group S14vsS20, we also found some BP terms associated with growth in the top 20 including actomyosin structure organization, actin cytoskeleton organization and myofibril assembly. (researchsquare.com)
Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton. (thermofisher.com)

Myosin light chain isoform expression among single mammalian skeletal muscle fibers: species variations. (scbio.cn)
However in a theoretical research Davis concluded that a model based on kinetic parameters could not take into account the quick replacement of 1 myosin isoform by an additional that is seen [2]. (immune-source.com)
The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. (thermofisher.com)

Although the cause of the former is unknown, it might result from the selective loss of the thin filament actin and an associated decline in the internal drag during cross-bridge cycling. (biologists.com)
In the kinesin assay microtubules are present to stimulate ATPase, whereas for myosin the S1 domain is generated by proteolytic cleavage and this domain is used either directly on F-actin, or using a reconstituted thin filament / sarcomere assay. (cytoskeleton.com)
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. (thermofisher.com)

The anti-striated muscle (anti-SM) Ab refers to a class of antibodies against components of skeletal muscle including titin, the ryanodine receptor, myosin, and alpha-actin. (medscape.com)
Mutations and polymorphisms of the skeletal muscle alpha-actin gene (ACTA1). (qxmd.com)

213. Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod. (wisc.edu)

About half of the patients with negative results for anti-AChR Ab (seronegative MG) may have positive test results for antibody to muscle-specific kinase (MuSK), a receptor tyrosine kinase that is essential for neuromuscular junction development. (medscape.com)
Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of myosin light chain by myosin light chain kinase. (scbio.cn)
Purification and properties of troponin T kinase from rabbit skeletal muscle. (scbio.cn)
Network pharmacological analysis using the identified specific chemical constituents of IO extracts predicted protein kinase B (AKT)-dependent mechanisms to promote myogenesis and muscle regeneration. (ijbs.com)

This unique function positions Ozz within a system that facilitates sarcomeric myosin remodeling during muscle mass maturation and regeneration. (immune-source.com)
We all report in this article that the sarcomeric embryonic myosin heavy cycle (MyHCemb/Myh3) may be a novel base of Ozz which especially recognizes the rod sector or butt region with this protein. (immune-source.com)

It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE . (nih.gov)

BLT2 ligation facilitates F-actin assembly with the upregulated phosphorylation of MYPT1. (cusabio.com)

In addition to the conventional complexes, as enzyme-inhibitor and antibody-antigen, interactions can also be established between domain-domain and domain-peptide. (wikipedia.org)
The following product was used in this experiment: beta Actin Loading Control Monoclonal Antibody (BA3R) from Thermo Fisher Scientific, catalog # MA5-15739, RRID AB_10979409. (thermofisher.com)
The blots were probed with Anti-beta Actin Mouse Monoclonal Antibody (Product # MA5-15739-1MG, 1:1000. (thermofisher.com)

For example, the maximal voluntary contraction of the human plantar flexor muscles declined by 20-48% following 6 months in space, while a 21% decline in the peak force of the soleus type I fibers was observed after a 17-day shuttle flight. (biologists.com)
This increase can be attributed both to an elevated maximal shortening velocity ( V 0 ) of the individual slow and fast fibers and to an increased expression of fibers containing fast myosin. (biologists.com)
The role of Dp71 in fiber cells was also suggested by the progressive disorganization of the lens fibers, which was observed in the absence of Dp71 and demonstrated by irregular staining of the actin network and the aqueous channel AQP0. (molvis.org)
The embryonic skeletal muscle development determines the number of muscle fibers and will affect the muscle production of chickens. (researchsquare.com)
Muscle spindle sensory signals are shaped not only by the movements and forces on the body, but also by motor commands to both the muscle (alpha drive) and to specialized muscle fibers in the muscle spindle mechanosensory region (gamma drive). (elifesciences.org)

Expression of the alpha 6A integrin splice variant in developing mouse embryonic stem cell aggregates and correlation with cardiac muscle differentiation. (scbio.cn)
In the study, we collected chicken leg muscles at 14 and 20-day embryonic ages both in the fast- and slow-growing groups for RNA-seq We identified 245 and 440 differentially expressed (DE) circRNAs in the comparison group F14vsF20 and S14vsS20 respectively. (researchsquare.com)
These findings would guide our next research and it would also lay a theoretical foundation for further improving the development mechanism of embryonic skeletal muscle. (researchsquare.com)

Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. (thermofisher.com)

HS has been shown to rapidly decrease muscle mass in plantar flexor muscles of rodents and this appears to have a mitochondrial role in muscle loss [ 36 ]. (hindawi.com)
We have studied unloading in plantar flexor muscles of aged rats or mice for many years [ 29 , 37 - 50 ]. (hindawi.com)

The reduced force can be attributed both to muscle atrophy and to a selective loss of contractile protein. (biologists.com)
Muscles contractile aminoacids are stated as a number of developmental isoforms that are in constant vibrant remodeling during embryogenesis although how outdated molecules will be recognized and removed can be not known. (immune-source.com)
Launch Striated muscle mass cells show the paradoxical association of a rigidly ordered fine structure with the ability to adjust their size and contractile properties during growth and development or in response to changes in their patterns of use. (immune-source.com)
Here, a biophysical model demonstrates that well-known firing characteristics of mammalian muscle spindle Ia afferents - including movement history dependence, and nonlinear scaling with muscle stretch velocity - emerge from first principles of muscle contractile mechanics. (elifesciences.org)

Neural crest cells play a vital role in the development of smooth muscle throughout the body, specifically in the regulation of blood vessels. (statpearls.com)
Interestingly ubiquitin-dependent degradation has also been indirectly implicated in the regulation of myosin folding and assembly [11]. (immune-source.com)

Myosin heavy chains are encoded by the MYH gene family and have Actin-activated ATPase activity which generates the motor function of Myosin. (scbio.cn)

The authors call the mutual sequestration mechanism through which pCPI-17 and myosin light-chain phosphatase interact inhibition by unfair competition: myosin light-chain phosphatase protects pCPI-17 from other phosphatases, while pCPI-17 blocks other substrates from the active site of myosin light-chain phosphatase. (cusabio.com)
Myosin light chain phosphatase (MLCP) is a master regulator of smooth muscle responsiveness to stimuli. (cusabio.com)
Purification and characterization of smooth muscle myosin-associated phosphatase from chicken gizzards. (scbio.cn)

as opposed to the soluble pool of myosin. (immune-source.com)
The classic suggestion of how such mechanisms may operate is founded on experiments where myosin monomers spontaneously polymerize to reach a dynamic equilibrium between fully polymerized myosin and a small pool of soluble monomers [1]. (immune-source.com)
Evidence to get ubiquitin-mediated degradation of myosin is mostly indirect but the E3 ubiquitin ligases MuRF1 which is induced during muscle atrophy and MuRF3 mediate the ubiquitination of soluble myosin [8] [9] binding to Indigo multiple sites near the head region of MyHC molecules. (immune-source.com)
water-soluble Resonance Spectroscopy: suitable signal of Vessel-carrying the new collagen of female individuals Skeletal as double frequencies, types or viscus. (augenta.net)

Three types of troponins exist-troponin I, troponin T, and troponin C. Each subunit has a unique function: Troponin T binds the troponin components to tropomyosin, troponin I inhibits the interaction of myosin with actin, and troponin C contains the binding sites for Ca 2+ that helps initiate contraction. (medscape.com)

It most commonly interacts with Myosin Va, an Actin based motor that can move in large steps. (scbio.cn)
Our findings identify Ozz-E3 because the ubiquitin ligase complex that interacts with and regulates myosin within its fully assembled cytoskeletal structure. (immune-source.com)

Another important structure is the calcium-containing sarcoplasmic reticulum, which aids in sustaining contraction. (statpearls.com)
In this study, we tested if calcium HMB (Ca-HMB) would improve muscle function and alter apoptotic signaling in the extensor digitorum longus (EDL) of aged animals that were unloaded but did not undergo atrophy. (hindawi.com)

citation needed] Physiology of muscle contraction involves several interactions. (wikipedia.org)

These data indicate that (i) increased apoptotic signaling preceded muscle atrophy or occurred without significant EDL atrophy and (ii) that Ca-HMB treatment did not improve EDL signaling, muscle mass, or muscle function in aged rats, when HS and R did not impact mass or function. (hindawi.com)

In addition to fiber atrophy and the loss of force and power, weightlessness reduces the ability of the slow soleus to oxidize fats and increases the utilization of muscle glycogen, at least in rats. (biologists.com)
Finally, with return to the 1 g environment of earth, rat studies have shown an increased occurrence of eccentric contraction-induced fiber damage. (biologists.com)
Ozz manifestation is muscle-specific and upregulated during muscle fiber differentiation but we demonstrate here that must be downregulated in muscle atrophy. (immune-source.com)

They are also less likely to respond to acetylcholine esterase (AChE) inhibitors, and their symptoms may actually worsen with these medications. (medscape.com)
Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. (lookformedical.com)

Hindlimb suspension (HS) has been used widely as a preclinical model of atrophy to study a variety of skeletal muscle adaptations including reduced gravity, disuse, and reloading (R) following disuse [ 30 - 35 ]. (hindawi.com)

and downregulation of ribosomes, oxidative metabolism, and mitochondrial gene transcripts in the vastus lateralis muscles of human [ 21 ]. (hindawi.com)
ebook military rule in chest: A subsequent gene in which the resembling hypertrophy natriuretic disease has less than 140 protein per blood and the 30-, 60-, or animal loss muscle dairy comprising a fibrinogen care literature is 200 failure per atherogenesis. (augenta.net)

Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. (thermofisher.com)

An initial small elevation occurs when troponins are released from the cytosolic pool, when troponin molecules in the cytosol of cardiac muscle diffuse across the sarcolemma into the surrounding lymphatics and blood vessels, becoming detectable in blood. (medscape.com)

A highly sensitive technique to measure myosin regulatory light chain phosphorylation: the first quantification in renal arterioles. (scbio.cn)

The primary deleterious changes are muscle atrophy and the associated decline in peak force and power. (biologists.com)
For both species, the antigravity soleus muscle showed greater atrophy than the fast-twitch gastrocnemius. (biologists.com)
However, it was less clear if HMB would alter dorsiflexor muscle response to unloading or reloading when there was no significant atrophy that was induced by unloading. (hindawi.com)

In fact, we now think that in response to oxidative stress, the mitochondrion relies on the Lynen Cycle to make more cells and the major source of energy becomes glycolytic, which is at the expense of the lean body mass (muscle), which produces gluconeogenic precursors from muscle proteolysis (cancer cachexia). (pharmaceuticalintelligence.com)

It plays an important role in signal transduction pathways, where it acts as a second messenger, in neurotransmitter release from neurons, contraction of all muscle cell types, and fertilization. (drugbank.com)
MYL6B is expressed in most tissues with neurons and smooth muscle tissue having the highest expression. (scbio.cn)
Independent activation of alpha and gamma motor neurons show that they can each profoundly alter muscle spindle sensory signals, rendering a direct prediction of muscle spindle signals from recordings of movement highly unlikely. (elifesciences.org)

MYL6B (Myosin light chain 6B) is a heavy chain regulator found in smooth muscle and non-muscle Myosin complexes. (scbio.cn)

MMPs could also promote venous dilation by increasing the release of endothelium-derived vasodilators and activating potassium channels, leading to smooth muscle hyperpolarization and relaxation. (oaepublish.com)
Sulodexide has also shown benefits in VLU and CVI, and recent data suggest that it could improve venous smooth muscle contraction. (oaepublish.com)
MMPs are negatively controlled by endogenous tissue inhibitors of metalloproteinases (TIMPs), and an imbalance between MMPs and TIMPs could contribute to venous dysfunction and CVD [ 1 , 5 ] . (oaepublish.com)
pdf Amyloid Precursor Lutea: An venous muscle in the testing, 3 to 5 glucose in tube, much measured new to the discriminating hypertrophy of the chamber and then below the availability of the local Modification. (augenta.net)

Beta-actin N-terminal peptide. (thermofisher.com)

77 Synchronicity of ventricular contraction 78 Reflexes arising from the heart 78 Renal function 78 Extrinsic (autonomic) factors 78 Intrinsic factors (autoregulation) 79 Renal blood flow distribution 79 Kallidin and renal function 80 Catechol amines 80 Norepinephrine refractoriness 80 Action of ephedrine sulfate 80 Laboratory of kidney and electrolyte metabolism. (nih.gov)
85 Cardioglobulin 86 CONTENTS IX Page Laboratory of metabolism 86 Pathway and inhibitors of cholesterol biosyn- thesis 87 Normal pathway of cholesterol biosyn- thesis 87 Desmosterol reductase 87 Desmosterol as precursor of adrenal ste- roids and bile acids 88 Sterol metabolism in skin and optic lens. (nih.gov)
The finding that BDNF is also secreted by differentiated human muscle cells and induces insulin secretion in human islets via TrkB.T1 identifies a new regulatory function of BDNF on metabolism that is independent of CNS activity. (nih.gov)
Much effort is made to develop agents to enhance muscle metabolism and function. (ijbs.com)
Here, we aimed to investigate the beneficial effect of IO extract in muscle regeneration and metabolism. (ijbs.com)
Our current data suggest that IO is a promising natural agent in enhancing muscle regenerative capacity and oxidative metabolism thereby preventing muscle wasting. (ijbs.com)

The nervous system instead uses hormones, neurotransmitters, and other receptors to control smooth muscle spontaneously. (statpearls.com)

Our purpose is to summarize the major effects of space travel on skeletal muscle with particular emphasis on factors that alter function. (biologists.com)
In addition, SICA-HF focussed on skeletal muscle function and wasting as well as on adipose tissue signalling. (europa.eu)
MMPs have also been shown to affect endothelial function and VSM contraction mechanisms [ 3 , 4 ] . (oaepublish.com)
The function of miRNAs in skeletal muscle has been gradually revealed in chicken. (researchsquare.com)

Further, mechanical interactions of the muscle spindle with muscle-tendon dynamics reveal how motor commands to the muscle (alpha drive) versus muscle spindle (gamma drive) can cause highly variable and complex activity during active muscle contraction and muscle stretch that defy simple explanation. (elifesciences.org)

Muscle loss is also associated with an increase in apoptotic signaling in myonuclei and satellite cells in fast- and slow-contracting limb muscles from older animals and humans [ 15 , 22 - 27 ]. (hindawi.com)
Chicken provides humans with a large amount of animal protein every year, in which skeletal muscle plays a leading role. (researchsquare.com)

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder causing progressive muscle degeneration and death. (molvis.org)

MMPs could also affect vascular smooth muscle (VSM) cell proliferation, migration, differentiation and/or apoptosis. (oaepublish.com)
IO treatment in mice improved the regeneration of cardiotoxin-injured muscles accompanied by elevated proliferation and differentiation of muscle stem cells. (ijbs.com)

During this download the signals detail to gain, appear to react phagosome decades and induce several and stable developments of canonical muscles human as cassette recessive professional and NOTCH1 newscasts. (evakoch.com)
In the download Flower Family of Hh formation, POLB-mediated Gli R-Smads bind located to induce a nervous ERBB2 that is into the north-facing and is vitamin sense actin. (evakoch.com)

The nervous system can use smooth muscle to tightly regulate many of the body's subsystems for life with no thought from the user. (statpearls.com)

The study on the skeletal muscle mechanism of chickens would make contributions to future breeding work. (researchsquare.com)

However, studies on circRNAs in the chicken embryo muscle development are still lacking. (researchsquare.com)

Approximately 60% of the body's magnesium is present in bone, 20% is in muscle, and another 20% is in soft tissue and the liver. (medscape.com)

For full three-quarters, include:( 1) corrosive increases in Matrix Metalloproteinase Inhibitor Research, R. Whittaker, Research Focus, Vol. Patents( 1994) outer): 7-16,( 3) Curr. (augenta.net)

Smooth muscle is present throughout the body, where it serves a variety of functions. (statpearls.com)
Smooth muscle differs from skeletal muscle in a variety of ways, perhaps the most important being its ability to be contracted and controlled involuntarily. (statpearls.com)
Smooth muscle also plays an essential role in the disease process throughout the body. (statpearls.com)
The use of bronchodilators to relax airway smooth muscle is an important and life-saving treatment in asthmatics. (statpearls.com)
[1] Likewise, medications like metoclopramide can stimulate and promote gastric emptying by increasing smooth muscle signaling. (statpearls.com)
Perhaps one of the most well-known uses of medical therapy and smooth muscle is the use of nitrates in the treatment of ischemic heart disease. (statpearls.com)
[3] The uniquely significant impact that smooth muscle has throughout the body makes it an important topic for medical professionals to understand as many treatments at their core rely on modifying the signaling pathways that affect smooth muscle. (statpearls.com)
At a cellular level, smooth muscle functions as an involuntary non-striated muscle. (statpearls.com)
Smooth muscle cytoplasm contains large amounts of actin and myosin. (statpearls.com)
The shape of smooth muscle is fusiform, which is round in the center and tapering at each end. (statpearls.com)
Smooth muscle can tense and relax but has greater elastic properties than striated muscle. (statpearls.com)
this is because smooth muscle contributes to many different tissues throughout the body. (statpearls.com)
We found that fibroblast, smooth muscle and skeletal muscle microtissues strain softened but did not fluidize, and upon loading cessation, they regained their initial mechanical properties. (nature.com)
Smooth muscle cells do not contain troponins. (medscape.com)
Three general classes of Myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. (scbio.cn)

PP2A dephosphorylates MYPT1(pThr696) and thereby stimulates MP activity inducing dephosphorylation of eNOS(pThr497) and the 20 kDa myosin II light chains. (cusabio.com)

Consistently, IO treatment resulted in the activation of AKT, which suppressed muscle-specific ubiquitin E3 ligases induced by dexamethasone. (ijbs.com)

Additionally, BDNF is secreted by skeletal muscle and muscle-specific BDNF knockout phenocopies the β-cell TrkB.T1 deletion metabolic impairments. (nih.gov)
Increase of vinblastine accumulation by inhibitors of calmodulin-dependent cell functions in rat ascites hepatoma AH66 cells. (scbio.cn)
2004. J Muscle Res Cell Motil. (scbio.cn)
Beta-hydroxy-beta-methylbutyrate (HMB), a naturally occurring leucine metabolite, has been shown to attenuate plantar flexor muscle loss and increase myogenic stem cell activation during reloading after a period of significant muscle wasting by disuse in old rodents. (hindawi.com)

There are six different actin isoforms in human. (thermofisher.com)

Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. (lookformedical.com)

In addition, a total of 127 skeletal muscle biopsies and 92 fat tissue biopsies have been collected. (europa.eu)
Other lines of treatment including induction of endogenous tissue inhibitors of metalloproteinases and administration of exogenous synthetic inhibitors of MMPs are being explored, and could provide alternative strategies in the treatment of CVD. (oaepublish.com)

0 KbpsGenre: download isoprenoid synthesis in plants and microorganisms new concepts and experimental, Romance When her thermoplasty is a top book, early Ava electromagnetics with muscle, conducting into a case worksite where she is up fluid Contents and presynaptic synthetic communications. (cdseidel.de)

Organoid models are emerging as valuable tools to investigate viral biology and disease progression of COVID-19 The neuro-serine protease inhibitor (neuroserpin) Spn4A, is an antiviral biologic discovered in the Jean Lab (Department of Microbiology & Immunology, Life Sciences Institute, University of British Columbia) currently being explored as a SARS-CoV-2 entry inhibitor. (bioimagingnorthamerica.org)

[2] Research showed that nitrates, in combination with ace inhibitors, can improve patient mortality. (statpearls.com)

This reduces the number of myonuclei and/or myogenic stem cells (satellite cells) and thereby reduces the potential for muscle growth or repair [ 19 , 28 , 29 ]. (hindawi.com)

Anatomy53

Organisms20

Diseases10

Chemicals and Drugs94

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Psychiatry and Psychology1

Phenomena and Processes61

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Information Science3

Health Care1

Filaments9

Proteins9

Cytoskeleton6

Isoform3

Filament3

Alpha-actin2

Cardiac myosin1

Kinase4

Sarcomeric2

Ryanodine1

Facilitates1

Antibody3

Fibers5

Embryonic3

Cytoskeletal protein1

Plantar flexor muscles2

Contractile4

Regulation2

ATPase1

Phosphatase3

Soluble4

Tropomyosin1

Interacts2

Calcium2

Physiology1

Preceded muscle atrophy1

Fiber3

Acetylcholine2

Adaptations1

Gene2

Assays1

Troponin1

Phosphorylation1

Atrophy3

Proteolysis1

Neurons3

Complexes1

Venous4

Peptide1

Metabolism6

Spontaneously1

Function4

Dynamics1

Humans2

Muscular1

Differentiation2

Induce2

Regulate1

Mechanism1

Chicken1

Bone1

Increases1

Smooth muscle15

Chains1

Ubiquitin1

Cell4

Human1

Commonly1

Tissue2

Electromagnetics1

Disease progression1

Mortality1

Reduces1