Proliferating Cell Nuclear AntigenCell AgingCell ProliferationCell CycleCell Cycle ProteinsCell DivisionCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p21Cells, CulturedApoptosisCell Line, TumorSignal TransductionTelomereTumor Suppressor Protein p53beta-GalactosidaseAging, PrematureCell Cycle CheckpointsTelomeraseRetinoblastoma ProteinFibroblastsCell DifferentiationCell LineAgingDNA DamageG1 PhaseBiological ProcessesBlotting, WesternPhosphorylationGene Expression RegulationRNA, MessengerRNA, Small InterferingDown-RegulationFlow CytometryTime FactorsMitosisTelomere ShorteningReverse Transcriptase Polymerase Chain ReactionS PhaseRNA InterferenceCyclinsGene Expression Regulation, NeoplasticUp-RegulationBromodeoxyuridineDNA-Binding ProteinsImmunohistochemistryMice, Inbred C57BLStem CellsCyclin-Dependent Kinase Inhibitor p27TransfectionCell SurvivalEndothelial CellsMice, KnockoutReactive Oxygen SpeciesDose-Response Relationship, DrugPhenotypeOxidative StressCyclin D1Tumor Cells, CulturedTranscription FactorsProtein-Serine-Threonine KinasesTOR Serine-Threonine KinasesMolecular Sequence DataTumor Suppressor ProteinsEnzyme ActivationNuclear ProteinsG2 PhaseMutationHistonesCell MovementModels, BiologicalCell Transformation, NeoplasticG0 PhaseGene ExpressionG1 Phase Cell Cycle CheckpointsDNAKi-67 AntigenCell Growth ProcessesBase SequenceEpithelial CellsCyclin EG2 Phase Cell Cycle CheckpointsCyclin-Dependent Kinase 2Endothelium, VascularLymphocyte ActivationCell NucleusDNA ReplicationMenstrual CycleCyclin-Dependent Kinase 4Transcription, Geneticp38 Mitogen-Activated Protein KinasesAntineoplastic AgentsProto-Oncogene Proteins c-mycGene Expression ProfilingProto-Oncogene ProteinsMice, NudeCyclin AEnzyme InhibitorsThymidineAmino Acid SequenceMice, Transgenic